C4 Therapeutics (CCCC) Short Interest Ratio & Short Volume $1.34 -0.14 (-9.12%) As of 02:25 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock C4 Therapeutics Short Interest DataC4 Therapeutics (CCCC) has a short interest of 6.41 million shares. This marks a -17.08% decrease in short interest from the previous month. The short interest ratio (days to cover) is 5.1, indicating that it would take 5.1 days of the average trading volume of 1.39 million shares to cover all short positions.Current Short Interest6,410,000 sharesPrevious Short Interest7,730,000 sharesChange Vs. Previous Month-17.08%Dollar Volume Sold Short$10.51 millionShort Interest Ratio5.1 Days to CoverLast Record DateApril 30, 2025Outstanding Shares71,007,000 sharesPercentage of Shares Shorted9.03%Today's Trading Volume529,108 sharesAverage Trading Volume1,390,040 sharesToday's Volume Vs. Average38% Short Selling C4 Therapeutics? Sign up to receive the latest short interest report for C4 Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartCCCC Short Interest Over TimeCCCC Days to Cover Over TimeCCCC Percentage of Float Shorted Over Time C4 Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 4/30/20256,410,000 shares $10.51 million -17.1%N/A5.1 $1.64 4/15/20257,730,000 shares $9.20 million -0.4%12.0%5.6 $1.19 3/31/20257,760,000 shares $12.42 million -5.0%12.0%5.4 $1.60 3/15/20258,170,000 shares $16.59 million -4.4%12.7%5 $2.03 2/28/20258,550,000 shares $23.17 million +6.1%13.2%4.7 $2.71 2/15/20258,060,000 shares $25.63 million +8.9%12.5%4.4 $3.18 1/31/20257,400,000 shares $25.68 million -20.3%N/A4.4 $3.47 1/15/20259,280,000 shares $37.49 million +7.9%N/A6 $4.04 12/31/20248,600,000 shares $30.96 million -3.0%N/A6.4 $3.60 12/15/20248,870,000 shares $38.85 million +11.0%N/A7.3 $4.38 Get the Latest News and Ratings for CCCC and Related StocksEnter your email address below to receive the latest news and analysts' ratings for C4 Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 11/30/20247,990,000 shares $36.35 million +8.0%N/A7.3 $4.55 11/15/20247,400,000 shares $31.89 million +26.5%N/A7.3 $4.31 10/31/20245,850,000 shares $31.18 million -12.0%N/A6 $5.33 10/15/20246,650,000 shares $41.90 million -39.6%N/A6.7 $6.30 9/30/202411,010,000 shares $62.76 million -7.6%N/A9 $5.70 9/15/202411,920,000 shares $76.76 million +2.5%N/A8.1 $6.44 8/31/202411,630,000 shares $73.50 million +10.8%N/A7.4 $6.32 8/15/202410,500,000 shares $61.53 million +0.3%N/A6.6 $5.86 7/31/202410,470,000 shares $70.15 million -10.0%N/A6.3 $6.70 7/15/202411,630,000 shares $75.48 million +32.0%N/A7 $6.49 6/30/20248,810,000 shares $40.70 million -39.4%N/A5.7 $4.62 6/15/202414,540,000 shares $63.69 million +9.7%N/A10.2 $4.38 5/31/202413,260,000 shares $66.30 million +16.9%N/A8.4 $5.00 5/15/202411,340,000 shares $69.29 million +11.8%N/A5.9 $6.11 4/30/202410,140,000 shares $63.88 million +6.1%N/A4.5 $6.30 4/15/20249,560,000 shares $65.58 million +4.5%N/A3.7 $6.86 3/31/20249,150,000 shares $74.76 million +73.0%N/A2.4 $8.17 3/15/20245,290,000 shares $47.24 million +78.1%N/A1.1 $8.93 2/29/20242,970,000 shares $32.61 million -6.6%N/A0.2 $10.98 2/15/20243,180,000 shares $25.12 million -5.1%N/A0.2 $7.90 1/31/20243,350,000 shares $20.70 million -39.6%8.7%0.2 $6.18 1/15/20245,550,000 shares $37.74 million +22.3%14.5%0.4 $6.80 12/31/20234,540,000 shares $25.65 million -44.0%10.8%0.3 $5.65 12/15/20238,100,000 shares $40.10 million +330.9%19.3%0.7 $4.95 11/30/20231,880,000 shares $3.06 million -3.6%4.5%3.4 $1.63 11/15/20231,950,000 shares $3.51 million +2.1%4.7%4.1 $1.80 10/31/20231,910,000 shares $2.85 million +4.4%4.6%3.9 $1.49 10/15/20231,830,000 shares $3.64 million -19.0%4.6%3.8 $1.99 9/30/20232,260,000 shares $4.20 million -5.0%5.6%5.2 $1.86 9/15/20232,380,000 shares $5.31 million +14.4%5.9%2.4 $2.23Trump wipes out trillions overnight… (Ad)Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out nearly $5 trillion in wealth from the S&P 500 and $6.4 trillion from the Dow Jones… Not to mention the countless trillions of dollars lost in every market around the world… leaving the major political powers scrambling in fear of Trump’s next move.Whether you take some of that wealth for yourself depends on if you watch this controversial exposé 8/31/20232,080,000 shares $6.03 million +9.5%5.2%1.9 $2.90 8/15/20231,900,000 shares $6.42 million -10.0%4.7%1.6 $3.38 7/31/20232,110,000 shares $8.21 million -5.8%5.3%1.7 $3.89 7/15/20232,240,000 shares $7.50 million -8.9%5.6%1.8 $3.35 6/30/20232,460,000 shares $6.77 million -26.4%6.1%2 $2.75 6/15/20233,340,000 shares $12.06 million +2.8%8.3%5.1 $3.61 5/31/20233,250,000 shares $11.02 million +12.1%8.1%5.4 $3.39 5/15/20232,900,000 shares $9.69 million +0.7%7.2%5.2 $3.34 4/30/20232,880,000 shares $8.70 million +1.8%7.0%5 $3.02 4/15/20232,830,000 shares $9.48 million +7.6%6.9%4.9 $3.35 3/31/20232,630,000 shares $8.26 million -9.9%6.5%4.5 $3.14 3/15/20232,920,000 shares $12.59 million -10.2%7.2%5.1 $4.31 2/28/20233,250,000 shares $17.13 million +0.9%8.0%6.3 $5.27 2/15/20233,220,000 shares $18.58 million -12.5%7.9%6.1 $5.77 1/31/20233,680,000 shares $28.67 million +2.8%9.0%7 $7.79 1/15/20233,580,000 shares $30.57 million +2.0%8.8%7.8 $8.54 12/30/20223,510,000 shares $20.71 million -3.6%8.6%7.8 $5.90 12/15/20223,640,000 shares $29.48 million +0.3%8.9%8 $8.10 11/30/20223,630,000 shares $31.11 million -8.1%8.9%7.5 $8.57 11/15/20223,950,000 shares $38.39 million -19.1%9.7%8.5 $9.72 10/31/20224,880,000 shares $46.95 million -1.2%11.9%11.4 $9.62 10/15/20224,940,000 shares $39.32 million -2.0%12.9%12.1 $7.96 9/30/20225,040,000 shares $44.20 million +11.0%13.2%11.9 $8.77 9/15/20224,540,000 shares $51.57 million -6.8%11.8%9.8 $11.36 8/31/20224,870,000 shares $49.09 million -5.1%12.7%9.9 $10.08 8/15/20225,130,000 shares $62.23 million -3.2%13.4%9.2 $12.13 7/31/20225,300,000 shares $51.09 million +1.5%13.9%8.2 $9.64 7/15/20225,220,000 shares $52.30 million +2.8%13.7%7.2 $10.02 6/30/20225,080,000 shares $38.30 million +20.7%13.3%4.7 $7.54 6/15/20224,210,000 shares $23.11 million -2.1%11.0%3.7 $5.49 5/31/20224,300,000 shares $31.22 million +10.3%11.3%4.2 $7.26 5/15/20223,900,000 shares $27.89 million -23.7%10.2%3.9 $7.15 4/30/20225,110,000 shares $43.79 million -4.7%13.4%5.4 $8.57 4/15/20225,360,000 shares $47.97 million +4.7%14.0%5.8 $8.95 3/31/20225,120,000 shares $124.21 million +8.5%13.4%7.2 $24.26 3/15/20224,720,000 shares $101.48 million +29.7%12.4%9.8 $21.50 2/28/20223,640,000 shares $81.65 million +8.7%9.5%7.6 $22.43 2/15/20223,350,000 shares $80.03 million +23.2%8.8%7.7 $23.89 1/31/20222,720,000 shares $66.45 million -13.1%7.1%6.7 $24.43 1/15/20223,130,000 shares $86.20 million -1.6%8.1%9.5 $27.54 12/31/20213,180,000 shares $102.40 million +6.0%8.3%10.9 $32.20 12/15/20213,000,000 shares $91.50 million +8.3%7.8%11 $30.50 11/30/20212,770,000 shares $102.82 million +0.4%7.2%10.6 $37.12 11/15/20212,760,000 shares $115.09 million +2.2%7.2%10.3 $41.70 10/29/20212,700,000 shares $119.93 million +1.5%7.0%9.9 $44.42 10/15/20212,660,000 shares $116.75 million No Change6.9%8.7 $43.89 9/30/20212,660,000 shares $118.85 million +17.2%6.9%7.9 $44.68 9/15/20212,270,000 shares $110.75 million -6.2%5.9%5.7 $48.79 8/31/20212,420,000 shares $97.11 million -11.7%6.6%5.5 $40.13 8/13/20212,740,000 shares $107.82 million +3.4%7.4%6 $39.35Trump’s Bitcoin Reserve is No Accident… (Ad)Bryce Paul believes this is the #1 coin to buy right now The catalyst behind this surge is a massive new blockchain development…Just click here to get all the details on this crypto coin now 7/30/20212,650,000 shares $114.32 million No Change8.1%5.5 $43.14 7/15/20212,650,000 shares $98.90 million -5.0%8.1%5.8 $37.32 6/30/20212,790,000 shares $105.57 million +18.2%8.5%6 $37.84 6/15/20212,360,000 shares $88.88 million -3.7%7.2%5.5 $37.66 5/28/20212,450,000 shares $90.53 million -7.9%7.4%6.4 $36.95 5/14/20212,660,000 shares $90.60 million +1.9%8.0%7.7 $34.06 4/30/20212,610,000 shares $89.37 million -12.1%7.9%8.6 $34.24 4/15/20212,970,000 shares $98.54 million -19.1%9.0%10.3 $33.18 3/31/20213,670,000 shares $120.74 million +77.3%11.1%13.8 $32.90 3/15/20212,070,000 shares $92.40 million +6.7%6.4%8 $44.64 2/26/20211,940,000 shares $81.00 million +21.3%5.9%7.7 $41.75 2/12/20211,600,000 shares $72.86 million +3.9%4.8%5.5 $45.54 1/29/20211,540,000 shares $55.70 million -14.9%4.4%3.9 $36.17 1/15/20211,810,000 shares $68.73 million No Change5.2%3.8 $37.97 CCCC Short Interest - Frequently Asked Questions What is C4 Therapeutics' current short interest? Short interest is the volume of C4 Therapeutics shares that have been sold short but have not yet been closed out or covered. As of April 30th, traders have sold 6,410,000 shares of CCCC short. Learn More on C4 Therapeutics' current short interest. What is a good short interest ratio for C4 Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. CCCC shares currently have a short interest ratio of 5.0. Learn More on C4 Therapeutics's short interest ratio. Which institutional investors are shorting C4 Therapeutics? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of C4 Therapeutics: Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is C4 Therapeutics' short interest increasing or decreasing? C4 Therapeutics saw a decrease in short interest in April. As of April 30th, there was short interest totaling 6,410,000 shares, a decrease of 17.1% from the previous total of 7,730,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does C4 Therapeutics' short interest compare to its competitors? Here is how the short interest of companies in the industry of "pharmaceutical products" compare to C4 Therapeutics: SIGA Technologies, Inc. (10.24%), Zevra Therapeutics, Inc. (10.35%), Sage Therapeutics, Inc. (8.48%), Amylyx Pharmaceuticals, Inc. (6.30%), Prothena Co. plc (13.84%), PureTech Health plc (0.04%), ABIVAX Société Anonyme (2.48%), Tourmaline Bio, Inc. (19.89%), Precigen, Inc. (16.99%), REGENXBIO Inc. (10.31%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Spotify Technology S.A. ($4.67 billion), Charter Communications, Inc. ($4.58 billion), Capital One Financial Co. ($4.47 billion), The Kroger Co. ($2.56 billion), Reddit, Inc. ($2.23 billion), Rivian Automotive, Inc. ($2.16 billion), Live Nation Entertainment, Inc. ($1.90 billion), SoFi Technologies, Inc. ($1.85 billion), Zscaler, Inc. ($1.75 billion), and Omnicom Group Inc. ($1.75 billion). View all of the most shorted stocks. What does it mean to sell short C4 Therapeutics stock? Short selling CCCC is an investing strategy that aims to generate trading profit from C4 Therapeutics as its price is falling. CCCC shares are trading down $0.14 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against C4 Therapeutics? A short squeeze for C4 Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of CCCC, which in turn drives the price of the stock up even further. How often is C4 Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including CCCC, twice per month. The most recent reporting period available is April, 30 2025. More Short Interest Resources from MarketBeat Related Companies SIGA Short Interest ZVRA Short Interest SAGE Short Interest AMLX Short Interest PRTA Short Interest PRTC Short Interest ABVX Short Interest TRML Short Interest PGEN Short Interest RGNX Short Interest Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:CCCC) was last updated on 5/21/2025 by MarketBeat.com Staff From Our PartnersMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. By the time he left, it had soared to $1,839. ...Premier Gold Co | SponsoredWhite House to reset Social Security?Elon Musk's parting DOGE gift looks set to shock America... 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