Denali Therapeutics (DNLI) News Today $13.21 -0.21 (-1.56%) Closing price 05/27/2025 04:00 PM EasternExtended Trading$13.65 +0.44 (+3.32%) As of 05/27/2025 07:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock DNLI Latest News All Sources Trusted Sources MarketBeat Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 October 2022 September 2022 August 2022 July 2022 June 2022 Time Period Polar Asset Management Partners Inc. Increases Stake in Denali Therapeutics Inc. (NASDAQ:DNLI)Polar Asset Management Partners Inc. increased its stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 1,240.9% in the fourth quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The institutional investor owned 551,09May 27 at 7:08 AM | marketbeat.comUBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Cuts Stock Holdings in Denali Therapeutics Inc. (NASDAQ:DNLI)UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC lowered its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 4.4% during the 4th quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission. The fund owned 3,582,May 27 at 4:46 AM | marketbeat.comWoodline Partners LP Makes New $2.04 Million Investment in Denali Therapeutics Inc. (NASDAQ:DNLI)Woodline Partners LP bought a new position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) in the fourth quarter, according to the company in its most recent Form 13F filing with the SEC. The fund bought 100,000 shares of the company's stock, valued at approximately $2,038,000. Woodline ParMay 27 at 4:31 AM | marketbeat.comMillennium Management LLC Acquires 344,056 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Millennium Management LLC grew its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 571.8% during the fourth quarter, according to its most recent disclosure with the Securities & Exchange Commission. The fund owned 404,224 shares of the company's stock after purchasing an adMay 27 at 3:38 AM | marketbeat.comTwinbeech Capital LP Invests $5.19 Million in Denali Therapeutics Inc. (NASDAQ:DNLI)Twinbeech Capital LP purchased a new position in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) in the fourth quarter, according to its most recent filing with the Securities and Exchange Commission. The institutional investor purchased 254,586 shares of the company's stock, valuedMay 23, 2025 | marketbeat.comRafferty Asset Management LLC Buys 23,629 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Rafferty Asset Management LLC increased its stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 20.1% in the fourth quarter, according to the company in its most recent Form 13F filing with the Securities & Exchange Commission. The fund owned 141,310 shares of the company's stock aMay 22, 2025 | marketbeat.comPoint72 Asset Management L.P. Has $11.18 Million Position in Denali Therapeutics Inc. (NASDAQ:DNLI)Point72 Asset Management L.P. grew its position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 64.5% in the fourth quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The firm owned 548,739 shares of the company's stock afteMay 21, 2025 | marketbeat.comDeutsche Bank AG Buys 37,907 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Deutsche Bank AG increased its stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 15.8% in the 4th quarter, according to its most recent 13F filing with the SEC. The firm owned 277,853 shares of the company's stock after buying an additional 37,907 shares during the period.May 21, 2025 | marketbeat.comDenali Therapeutics (NASDAQ:DNLI) Price Target Cut to $27.00 by Analysts at Bank of AmericaMay 20, 2025 | americanbankingnews.comAnalysts Set Denali Therapeutics Inc. (NASDAQ:DNLI) Price Target at $33.79May 18, 2025 | americanbankingnews.comDenali Therapeutics Inc. (NASDAQ:DNLI) Shares Acquired by Polar Asset Management Partners Inc.Polar Asset Management Partners Inc. raised its stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 1,240.9% in the 4th quarter, according to its most recent filing with the SEC. The fund owned 551,092 shares of the company's stock after purchasing an additional 509,992 shares during tMay 17, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Receives Average Recommendation of "Buy" from AnalystsDenali Therapeutics Inc. (NASDAQ:DNLI - Get Free Report) has earned an average recommendation of "Buy" from the seventeen analysts that are covering the stock, Marketbeat.com reports. One investment analyst has rated the stock with a hold rating, fourteen have issued a buy rating and two have givMay 17, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Shares Bought by Northern Trust CorpNorthern Trust Corp grew its stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 10.7% in the fourth quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission. The firm owned 1,201,518 shares of the company's stock after acquiMay 15, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Shares Sold by Jane Street Group LLCJane Street Group LLC lowered its position in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 37.6% in the fourth quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund owned 229,165 shares of the company's stock after selMay 13, 2025 | marketbeat.comQ3 EPS Estimate for Denali Therapeutics Lowered by AnalystDenali Therapeutics Inc. (NASDAQ:DNLI - Free Report) - Leerink Partnrs decreased their Q3 2025 earnings estimates for shares of Denali Therapeutics in a report issued on Wednesday, May 7th. Leerink Partnrs analyst M. Goodman now expects that the company will post earnings per share of ($0.68) forMay 13, 2025 | marketbeat.comB. Riley Forecasts Lower Earnings for Denali TherapeuticsDenali Therapeutics Inc. (NASDAQ:DNLI - Free Report) - Equities researchers at B. Riley lowered their Q2 2025 earnings per share (EPS) estimates for shares of Denali Therapeutics in a research report issued on Wednesday, May 7th. B. Riley analyst M. Mamtani now expects that the company will postMay 13, 2025 | marketbeat.comHC Wainwright Issues Optimistic Estimate for DNLI EarningsDenali Therapeutics Inc. (NASDAQ:DNLI - Free Report) - Equities research analysts at HC Wainwright lifted their Q2 2025 earnings estimates for Denali Therapeutics in a research note issued on Wednesday, May 7th. HC Wainwright analyst A. Fein now expects that the company will earn ($0.68) per sharMay 13, 2025 | marketbeat.comQ2 EPS Estimates for Denali Therapeutics Raised by WedbushDenali Therapeutics Inc. (NASDAQ:DNLI - Free Report) - Analysts at Wedbush upped their Q2 2025 earnings per share estimates for Denali Therapeutics in a report released on Wednesday, May 7th. Wedbush analyst L. Chico now expects that the company will earn ($0.76) per share for the quarter, up froMay 13, 2025 | marketbeat.comFred Alger Management LLC Sells 29,509 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Fred Alger Management LLC lowered its holdings in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 24.3% in the 4th quarter, according to its most recent Form 13F filing with the Securities & Exchange Commission. The fund owned 91,807 shares of the company's stock after sellingMay 12, 2025 | marketbeat.comBalyasny Asset Management L.P. Grows Stock Holdings in Denali Therapeutics Inc. (NASDAQ:DNLI)Balyasny Asset Management L.P. boosted its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 822.4% in the fourth quarter, according to its most recent filing with the SEC. The institutional investor owned 416,074 shares of the company's stock after buying an additional 370,966 sMay 12, 2025 | marketbeat.comRaymond James Financial Inc. Invests $533,000 in Denali Therapeutics Inc. (NASDAQ:DNLI)Raymond James Financial Inc. acquired a new stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) in the 4th quarter, according to its most recent Form 13F filing with the SEC. The institutional investor acquired 26,143 shares of the company's stock, valued at approximately $533,000. A numMay 11, 2025 | marketbeat.comRobert W. Baird Has Lowered Expectations for Denali Therapeutics (NASDAQ:DNLI) Stock PriceRobert W. Baird lowered their target price on shares of Denali Therapeutics from $30.00 to $29.00 and set an "outperform" rating on the stock in a report on Thursday.May 10, 2025 | marketbeat.comHC Wainwright Cuts Denali Therapeutics (NASDAQ:DNLI) Price Target to $32.00HC Wainwright dropped their price target on shares of Denali Therapeutics from $80.00 to $32.00 and set a "buy" rating for the company in a research note on Wednesday.May 9, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Stock Position Decreased by Axa S.A.Axa S.A. decreased its position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 14.8% in the 4th quarter, according to the company in its most recent 13F filing with the SEC. The institutional investor owned 293,755 shares of the company's stock after selling 51,128 shares during the quMay 9, 2025 | marketbeat.comFirst Trust Advisors LP Acquires 47,308 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)First Trust Advisors LP lifted its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 260.9% during the fourth quarter, according to the company in its most recent Form 13F filing with the Securities & Exchange Commission. The institutional investor owned 65,442 shares of theMay 9, 2025 | marketbeat.comWilliam Blair Keeps Their Buy Rating on Denali Therapeutics (DNLI)May 8, 2025 | theglobeandmail.comDenali Therapeutics price target lowered to $29 from $30 at BairdMay 8, 2025 | msn.comCompanies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In GrowthMay 8, 2025 | finance.yahoo.comCrestline Management LP Has $87.85 Million Stake in Denali Therapeutics Inc. (NASDAQ:DNLI)Crestline Management LP decreased its position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 3.4% in the 4th quarter, according to the company in its most recent filing with the Securities & Exchange Commission. The institutional investor owned 4,310,732 shares of the company's stMay 8, 2025 | marketbeat.comDimensional Fund Advisors LP Has $37.81 Million Stock Position in Denali Therapeutics Inc. (NASDAQ:DNLI)Dimensional Fund Advisors LP lifted its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 19.0% in the 4th quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission. The fund owned 1,855,036 shares of the company's stock after purcMay 7, 2025 | marketbeat.comDenali Therapeutics Reports First Quarter 2025 Financial Results and Business Highlights Including Completion of BLA Rolling Submission for Tividenofusp Alfa for Hunter SyndromeMay 6, 2025 | globenewswire.comAquatic Capital Management LLC Purchases Shares of 15,694 Denali Therapeutics Inc. (NASDAQ:DNLI)Aquatic Capital Management LLC acquired a new position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) during the fourth quarter, according to its most recent filing with the SEC. The firm acquired 15,694 shares of the company's stock, valued at approximately $320,000. Several other hedge fMay 6, 2025 | marketbeat.comDenali Therapeutics (DNLI) Projected to Post Quarterly Earnings on TuesdayDenali Therapeutics (NASDAQ:DNLI) will be releasing its Q1 2025 earnings before the market opens on Tuesday, May 6. (View Earnings Report at https://www.marketbeat.com/earnings/reports/2025-5-6-denali-therapeutics-inc-stock/)May 1, 2025 | marketbeat.comSusquehanna Fundamental Investments LLC Acquires New Position in Denali Therapeutics Inc. (NASDAQ:DNLI)Susquehanna Fundamental Investments LLC bought a new position in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) during the 4th quarter, according to the company in its most recent filing with the SEC. The fund bought 192,563 shares of the company's stock, valued at approximately $3,May 1, 2025 | marketbeat.comPrice T Rowe Associates Inc. MD Grows Position in Denali Therapeutics Inc. (NASDAQ:DNLI)Price T Rowe Associates Inc. MD lifted its holdings in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 6.6% during the 4th quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund owned 3,058,615 shares of the company's stocMay 1, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Shares Sold by Invesco Ltd.Invesco Ltd. cut its position in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 41.1% in the fourth quarter, according to its most recent disclosure with the Securities and Exchange Commission. The institutional investor owned 121,478 shares of the company's stock after sellingApril 30, 2025 | marketbeat.comDenali Therapeutics (NASDAQ:DNLI) Upgraded to Strong-Buy at William BlairWilliam Blair raised Denali Therapeutics to a "strong-buy" rating in a report on Thursday.April 28, 2025 | marketbeat.comBarclays PLC Has $5.67 Million Stock Holdings in Denali Therapeutics Inc. (NASDAQ:DNLI)Barclays PLC grew its stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 8.7% during the 4th quarter, according to its most recent 13F filing with the Securities & Exchange Commission. The fund owned 278,067 shares of the company's stock after purchasing an additional 22April 28, 2025 | marketbeat.com24,820 Shares in Denali Therapeutics Inc. (NASDAQ:DNLI) Bought by Walleye Capital LLCWalleye Capital LLC bought a new stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) during the fourth quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund bought 24,820 shares of the company's stock, valued at approxiApril 26, 2025 | marketbeat.comGuggenheim Capital LLC Acquires 27,518 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Guggenheim Capital LLC lifted its holdings in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 133.5% during the fourth quarter, according to the company in its most recent Form 13F filing with the Securities & Exchange Commission. The institutional investor owned 48,131 shares of the cApril 25, 2025 | marketbeat.com60,000 Shares in Denali Therapeutics Inc. (NASDAQ:DNLI) Bought by Diadema Partners LPDiadema Partners LP purchased a new stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) during the fourth quarter, according to its most recent Form 13F filing with the Securities & Exchange Commission. The firm purchased 60,000 shares of the company's stock, valued at approApril 24, 2025 | marketbeat.comDenali Therapeutics (NASDAQ:DNLI) Stock Price Up 6.6% - Time to Buy?Denali Therapeutics (NASDAQ:DNLI) Stock Price Up 6.6% - Here's What HappenedApril 23, 2025 | marketbeat.comCapital Research Global Investors Decreases Stake in Denali Therapeutics Inc. (NASDAQ:DNLI)Capital Research Global Investors lowered its stake in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 30.7% in the 4th quarter, according to its most recent disclosure with the SEC. The fund owned 5,477,211 shares of the company's stock after selling 2,431,903 shares during the quarter. CaApril 23, 2025 | marketbeat.comMarshall Wace LLP Sells 178,404 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Marshall Wace LLP lessened its stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 9.1% in the 4th quarter, according to its most recent disclosure with the SEC. The firm owned 1,788,737 shares of the company's stock after selling 178,404 shares during the period. Marshall WaApril 21, 2025 | marketbeat.comDenali Therapeutics Inc. (NASDAQ:DNLI) Receives Consensus Recommendation of "Buy" from BrokeragesShares of Denali Therapeutics Inc. (NASDAQ:DNLI - Get Free Report) have received a consensus rating of "Buy" from the seventeen research firms that are presently covering the firm, Marketbeat Ratings reports. One investment analyst has rated the stock with a hold rating, fifteen have assigned a bApril 21, 2025 | marketbeat.comFmr LLC Buys 188,368 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Fmr LLC lifted its position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 2.4% during the 4th quarter, according to the company in its most recent filing with the SEC. The fund owned 8,019,746 shares of the company's stock after purchasing an additional 188,368 shares during the quarteApril 15, 2025 | marketbeat.comGeode Capital Management LLC Trims Stake in Denali Therapeutics Inc. (NASDAQ:DNLI)Geode Capital Management LLC lowered its position in Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 0.7% in the 4th quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission (SEC). The fund owned 2,935,283 shares of the company's stock afteApril 15, 2025 | marketbeat.comCantor Fitzgerald Analysts Lower Earnings Estimates for DNLIDenali Therapeutics Inc. (NASDAQ:DNLI - Free Report) - Equities researchers at Cantor Fitzgerald decreased their FY2025 earnings estimates for Denali Therapeutics in a research report issued to clients and investors on Thursday, April 10th. Cantor Fitzgerald analyst J. Schimmer now forecasts thatApril 15, 2025 | marketbeat.comDenali Therapeutics (NASDAQ:DNLI) Stock Rating Upgraded by Cantor FitzgeraldCantor Fitzgerald raised Denali Therapeutics from a "neutral" rating to an "overweight" rating in a research report on Thursday.April 12, 2025 | marketbeat.comTrexquant Investment LP Buys 36,122 Shares of Denali Therapeutics Inc. (NASDAQ:DNLI)Trexquant Investment LP increased its stake in shares of Denali Therapeutics Inc. (NASDAQ:DNLI - Free Report) by 147.2% during the 4th quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission (SEC). The fund owned 60,656 shares of the company's stock after pApril 12, 2025 | marketbeat.com Get Denali Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for DNLI and its competitors with MarketBeat's FREE daily newsletter. Email Address DNLI Media Mentions By Week DNLI Media Sentiment Learn about the media sentiment score. Each headline receives a score ranging from 2 (good news) to -2 (bad news). Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. DNLI News Sentiment▼1.531.03▲Average Medical News Sentiment DNLI News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. DNLI Articles This Week▼96▲DNLI Articles Average Week Get Denali Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for DNLI and its competitors with MarketBeat's FREE daily newsletter. 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