Denali Therapeutics (DNLI) Short Interest Ratio & Short Volume

Short interest is the volume of Denali Therapeutics shares that have been sold short but have not yet been covered or closed out. As of May 31st, investors have sold 12,220,000 shares of DNLI short. 9.72% of Denali Therapeutics' shares are currently sold short. Learn More on Denali Therapeutics' current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. DNLI shares currently have a short interest ratio of 8.0. Learn More on Denali Therapeutics's short interest ratio.

As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Denali Therapeutics: Caption Management LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 9.72% of Denali Therapeutics' floating shares are currently sold short.

Denali Therapeutics saw a increase in short interest in May. As of May 31st, there was short interest totaling 12,220,000 shares, an increase of 1.0% from the previous total of 12,100,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

Denali Therapeutics currently has issued a total of 145,276,000 shares. Some of Denali Therapeutics' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Denali Therapeutics currently has a public float of 125,730,000 shares.

9.72% of Denali Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Denali Therapeutics: Blueprint Medicines Co. (9.93%), Roivant Sciences Ltd. (10.63%), Revolution Medicines, Inc. (11.86%), BridgeBio Pharma, Inc. (15.35%), Elanco Animal Health Incorporated (5.32%), Verona Pharma plc (9.37%), Legend Biotech Co. (7.03%), TG Therapeutics, Inc. (16.93%), Grifols, S.A. (1.19%), Lantheus Holdings, Inc. (11.91%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($64.96 billion), Invesco QQQ ($27.88 billion), iShares Russell 2000 ETF ($19.94 billion), iShares 20+ Year Treasury Bond ETF ($9.69 billion), Strategy Incorporated ($8.58 billion), SPDR S&P Biotech ETF ($5.72 billion), Invesco S&P 500 Equal Weight ETF ($5.45 billion), iShares iBoxx $ Investment Grade Corporate Bond ETF ($4.70 billion), Charter Communications, Inc. ($4.54 billion), and Industrial Select Sector SPDR Fund ($4.49 billion). View all of the most shorted stocks.

Short selling DNLI is an investing strategy that aims to generate trading profit from Denali Therapeutics as its price is falling. DNLI shares are trading down $0.07 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for Denali Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of DNLI, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including DNLI, twice per month. The most recent reporting period available is May, 31 2025.