Structure Therapeutics (GPCR) Institutional Ownership $19.30 +0.16 (+0.84%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$18.90 -0.40 (-2.07%) As of 08/29/2025 05:41 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Structure Therapeutics (NASDAQ:GPCR)CurrentInstitutional OwnershipPercentage91.78%Number ofInstitutional Buyers(last 12 months)113TotalInstitutional Inflows(last 12 months)$402.17MNumber ofInstitutional Sellers(last 12 months)55TotalInstitutional Outflows(last 12 months)$192.02M Get GPCR Insider Trade Alerts Want to know when executives and insiders are buying or selling Structure Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data GPCR Institutional Buying and Selling by Quarter Structure Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/19/2025 State of Wyoming1,330$28K0.0%N/A0.002% 8/18/2025 MASO CAPITAL PARTNERS Ltd13,000$270K0.5%N/A0.023% 8/16/2025 Headlands Technologies LLC22,338$463K0.1%+555.5%0.039% 8/15/2025 Exome Asset Management LLC53,744$1.12M0.6%-47.8%0.093% 8/15/2025 Vestal Point Capital LP1,200,000$24.89M1.3%-32.9%2.083% 8/15/2025 Sofinnova Investments Inc.34,353$712K0.0%-1.7%0.060% 8/15/2025 Engineers Gate Manager LP15,862$329K0.0%N/A0.028% 8/15/2025 BNP Paribas Financial Markets65,836$1.37M0.0%+1,357.2%0.114% 8/15/2025 Boothbay Fund Management LLC57,622$1.20M0.0%-25.5%0.100% 8/15/2025 Bellevue Group AG348,527$7.23M0.2%+57.2%0.605% Get the Latest News and Ratings for GPCR and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Structure Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 8/15/2025 Birchview Capital LP36,000$747K0.7%N/A0.063% 8/15/2025 Bank of America Corp DE13,908$288K0.0%-74.9%0.024% 8/15/2025 Ameriprise Financial Inc.1,588,198$32.94M0.0%+7.2%2.757% 8/14/2025 First Light Asset Management LLC122,226$2.54M0.3%-7.7%0.212% 8/14/2025 Paloma Partners Management Co20,950$435K0.1%N/A0.036% 8/14/2025 Orbimed Advisors LLC1,199,300$24.87M0.7%+49.5%2.082% 8/14/2025 Raymond James Financial Inc.6,229$129K0.0%N/A0.011% 8/14/2025 Canada Pension Plan Investment Board167,800$3.48M0.0%N/A0.291% 8/14/2025 HighVista Strategies LLC86,621$1.80M0.7%+393.3%0.150% 8/14/2025 Federated Hermes Inc.468,300$9.71M0.0%-60.0%0.813% 8/13/2025 Jump Financial LLC63,234$1.31M0.0%+105.9%0.110% 8/13/2025 Marshall Wace LLP176,060$3.65M0.0%+474.9%0.306% 8/13/2025 Invesco Ltd.424,548$8.81M0.0%+7.6%0.737% 8/13/2025 Quantbot Technologies LP2,888$60K0.0%-79.9%0.005% 8/13/2025 OMERS ADMINISTRATION Corp24,600$510K0.0%N/A0.043% 8/13/2025 Virtus Investment Advisers LLC4,232$88K0.0%-18.3%0.007% 8/13/2025 Tejara Capital Ltd22,400$465K0.2%N/A0.039% 8/13/2025 Quadrature Capital Ltd16,079$334K0.0%N/A0.028% 8/13/2025 Capital Fund Management S.A.14,350$298K0.0%-82.0%0.025% 8/13/2025 Rhenman & Partners Asset Management AB135,100$2.80M0.4%+93.0%0.235% 8/12/2025 Foresite Capital Management VI LLC210,000$4.36M2.4%-50.0%0.365% 8/12/2025 DCF Advisers LLC24,750$513K0.2%N/A0.043% 8/12/2025 American Century Companies Inc.491,193$10.19M0.0%-3.7%0.853% 8/12/2025 Franklin Resources Inc.741,783$15.39M0.0%+0.2%1.288% 8/12/2025 JPMorgan Chase & Co.42,442$880K0.0%-68.4%0.074% 8/12/2025 DNB Asset Management AS10,635$221K0.0%N/A0.018% 8/11/2025 Nomura Asset Management Co. Ltd.24,874$516K0.0%-14.2%0.043% 8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH11,914$247K0.0%-84.5%0.021% 8/8/2025 SG Americas Securities LLC19,239$399K0.0%N/A0.034% 8/8/2025 Good Life Advisors LLC15,000$311K0.0%+15.4%0.026% A New Way to Double Your Retirement Income? (Ad)Bloomberg reports that a new class of investments is “entering a golden era,” with yields fueling a retail boom. For retirees, that could mean a way to generate reliable monthly income—without the outdated 4% withdrawal rule, risky trading, or high-fee annuities. If you’re ready to stop worrying about money running out and start enjoying the freedom to cover expenses, treat loved ones, and live life on your terms, this may be exactly what you’ve been waiting for.Click here to see how to turn your savings into a monthly income machine.8/8/2025 Geode Capital Management LLC54,181$1.12M0.0%+18.5%0.094% 8/8/2025 PNC Financial Services Group Inc.4,415$92K0.0%+29.1%0.008% 8/8/2025 Quinn Opportunity Partners LLC42,000$871K0.1%+90.9%0.073% 8/5/2025 Bank of Montreal Can58,073$1.22M0.0%+9.1%0.101% 8/5/2025 ANTIPODES PARTNERS Ltd2,932$61K0.0%-31.0%0.005% 8/5/2025 Pier Capital LLC198,478$4.12M0.6%-6.6%0.346% 8/4/2025 Assetmark Inc.2,877$60K0.0%+39.9%0.005% 8/1/2025 Envestnet Asset Management Inc.10,676$221K0.0%N/A0.019% 7/30/2025 Pacific Heights Asset Management LLC460,000$9.54M0.5%N/A0.802% 7/29/2025 TrueMark Investments LLC37,765$783K0.2%-3.7%0.066% 7/28/2025 Allianz Asset Management GmbH11,000$228K0.0%N/A0.019% 7/25/2025 Griffin Asset Management Inc.11,205$232K0.0%N/A0.020% 7/24/2025 Aberdeen Group plc401,624$8.33M0.0%+61.4%0.700% 7/16/2025 Signaturefd LLC6,650$138K0.0%+6,550.0%0.012% 7/16/2025 Banque Pictet & Cie SA70,401$1.46M0.0%-13.9%0.123% 7/10/2025 Exchange Traded Concepts LLC61,732$1.28M0.0%+58.6%0.108% 7/8/2025 Parallel Advisors LLC8,264$171K0.0%N/A0.014% 5/16/2025 Woodline Partners LP175,424$3.04M0.0%-47.5%0.306% 5/16/2025 Zimmer Partners LP100,776$1.74M0.0%+77.1%0.176% 5/16/2025 Exome Asset Management LLC102,944$1.78M1.5%-32.3%0.180% 5/16/2025 Millennium Management LLC790,159$13.68M0.0%-19.8%1.378% 5/15/2025 First Light Asset Management LLC132,380$2.29M0.3%-66.8%0.231% 5/15/2025 Vestal Point Capital LP1,788,990$30.97M2.2%+3.7%3.120% 5/15/2025 Cubist Systematic Strategies LLC54,816$949K0.0%+3,326.0%0.096% 5/15/2025 Point72 Europe London LLP90,697$1.57M0.1%+188.7%0.158% 5/15/2025 DAFNA Capital Management LLC59,000$1.02M0.3%+66.2%0.103% 5/15/2025 Driehaus Capital Management LLC1,272,743$22.03M0.2%-38.1%2.220% 5/15/2025 Tema Etfs LLC22,590$391K0.1%-49.1%0.039% 5/15/2025 Trexquant Investment LP120,340$2.08M0.0%+127.6%0.210% 5/14/2025 Jump Financial LLC30,710$532K0.0%N/A0.054% 5/14/2025 Monashee Investment Management LLC292,862$5.07M0.6%+121.9%0.511% 5/14/2025 Candriam S.C.A.214,063$3.71M0.0%-0.6%0.373% 5/14/2025 Capital Fund Management S.A.79,656$1.38M0.0%+18.7%0.139% 5/14/2025 Quantbot Technologies LP14,401$249K0.0%N/A0.025% 5/14/2025 Wellington Management Group LLP7,791,183$134.87M0.0%+0.1%13.587% 5/13/2025 American Century Companies Inc.510,201$8.83M0.0%-16.7%0.890% 5/13/2025 Aberdeen Group plc248,899$4.31M0.0%+45.2%0.434% 5/12/2025 Invesco Ltd.394,386$6.83M0.0%+6.1%0.688% 5/12/2025 National Bank of Canada FI2,957$51K0.0%+1,448.2%0.005% 5/9/2025 Headlands Technologies LLC3,408$59K0.0%-18.1%0.006% 5/8/2025 Federated Hermes Inc.1,170,948$20.27M0.0%-42.8%2.042% 5/7/2025 TD Asset Management Inc43,686$756K0.0%-50.8%0.076% 5/6/2025 ANTIPODES PARTNERS Ltd4,247$74K0.0%+310.7%0.007% 5/6/2025 Readystate Asset Management LP481,241$8.33M0.3%+129.9%0.839% 5/6/2025 Universal Beteiligungs und Servicegesellschaft mbH76,863$1.33M0.0%-32.6%0.134% 4/30/2025 Alps Advisors Inc.43,080$746K0.0%-7.0%0.075% 4/30/2025 Banque Pictet & Cie SA81,766$1.42M0.0%+10.2%0.143% 4/30/2025 China Universal Asset Management Co. Ltd.11,951$207K0.0%-5.4%0.021% 4/28/2025 Principal Financial Group Inc.756,707$13.10M0.0%-4.4%1.320% 4/22/2025 TrueMark Investments LLC39,217$679K0.2%-6.9%0.068% A New Way to Double Your Retirement Income? (Ad)Bloomberg reports that a new class of investments is “entering a golden era,” with yields fueling a retail boom. For retirees, that could mean a way to generate reliable monthly income—without the outdated 4% withdrawal rule, risky trading, or high-fee annuities. If you’re ready to stop worrying about money running out and start enjoying the freedom to cover expenses, treat loved ones, and live life on your terms, this may be exactly what you’ve been waiting for.Click here to see how to turn your savings into a monthly income machine.4/17/2025 Exchange Traded Concepts LLC38,923$674K0.0%-3.7%0.068% 4/15/2025 Handelsbanken Fonder AB380,000$6.58M0.0%+130.3%0.663% 4/7/2025 GAMMA Investing LLC8,776$152K0.0%+663.8%0.015% 2/28/2025 Universal Beteiligungs und Servicegesellschaft mbH113,992$3.09M0.0%N/A0.199% 2/19/2025 GF Fund Management CO. LTD.1,251$34K0.0%N/A0.002% 2/17/2025 Woodline Partners LP333,901$9.06M0.1%+0.7%0.583% 2/17/2025 Zimmer Partners LP56,900$1.54M0.0%-73.0%0.099% 2/17/2025 Vestal Point Capital LP1,725,000$46.78M2.8%+50.0%3.013% 2/17/2025 Wexford Capital LP81,872$2.22M0.4%-16.6%0.143% 2/17/2025 Twinbeech Capital LP28,268$767K0.0%+34.3%0.049% (Data available from 1/1/2016 forward) GPCR Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of GPCR shares? During the previous two years, 181 institutional investors and hedge funds held shares of Structure Therapeutics. The most heavily invested institutionals were FMR LLC ($164.86M), Wellington Management Group LLP ($134.87M), Janus Henderson Group PLC ($112.82M), Capital Research Global Investors ($95.93M), Avoro Capital Advisors LLC ($95.11M), Adage Capital Partners GP L.L.C. ($90.75M), and Deep Track Capital LP ($75.94M).Learn more on Structure Therapeutics' institutional investors. What percentage of Structure Therapeutics' stock is owned by institutional investors? 91.78% of Structure Therapeutics' stock is owned by institutional investors. Learn more on GPCR's institutional investor holdings. Which institutional investors have been buying Structure Therapeutics' stock? Of the 165 institutional investors that purchased Structure Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Wellington Management Group LLP ($4.41M), Adage Capital Partners GP L.L.C. ($1.61M), Deep Track Capital LP ($1.58M), Federated Hermes Inc. ($1.40M), Capital International Investors ($1.38M), Janus Henderson Group PLC ($1.34M), and Avoro Capital Advisors LLC ($1.33M). How much institutional buying is happening at Structure Therapeutics? Institutional investors have bought a total of 13,260,974 shares in the last 24 months. This purchase volume represents approximately $402.17M in transactions. Which of Structure Therapeutics' major shareholders have been selling company stock? Of the 55 institutional investors that sold Structure Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Federated Hermes Inc. ($1.94M), Driehaus Capital Management LLC ($1.25M), Price T Rowe Associates Inc. MD ($690.38K), Vestal Point Capital LP ($588.99K), Deerfield Management Company L.P. Series C ($471K), BVF Inc. IL ($467.57K), and First Light Asset Management LLC ($384.00K). How much institutional selling is happening at Structure Therapeutics? Institutional investors have sold a total of 8,308,789 shares in the last 24 months. This volume of shares sold represents approximately $192.02M in transactions. 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