Mineralys Therapeutics (MLYS) Stock Price, News & Analysis

Company Overview

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for cardiovascular and kidney-related diseases. The company’s research is centered on conditions associated with excess aldosterone activity, including uncontrolled and resistant hypertension.

Mineralys’ lead investigational product is lorundrostat, also known as MLS-101, an oral, highly selective aldosterone synthase inhibitor. The company is evaluating lorundrostat in clinical studies as a potential treatment for patients whose blood pressure remains inadequately controlled despite existing therapy. Because the drug is investigational, its safety and effectiveness have not been established for any indication.

Mineralys was founded in 2017 and is based in the United States. The company has advanced lorundrostat through mid-stage clinical development and has pursued later-stage studies in hypertension, with research activities primarily focused on the U.S. market. Mineralys became a publicly traded company in 2023.

Key Stats

• Today's Range: $25.21 to $26.70
• 50-Day Range: $25.27 to $31.12
• 52-Week Range: $22.30 to $47.65
• Volume: 1.19 million shs
• Average Volume: 1.35 million shs
• Market Capitalization: $2.29 billion
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $48.80
• Consensus Rating: Moderate Buy

Mineralys Therapeutics Stock Analysis - MarketRank™

Mineralys Therapeutics scored higher than 55% of companies evaluated by MarketBeat, and ranked 461st out of 907 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.7 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Mineralys Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on no strong buy ratings, 5 buy ratings, 2 hold ratings, and 1 sell rating.

Upside Potential

Mineralys Therapeutics has a consensus price target of $48.80, representing about 88.7% upside from its current price of $25.86.

Amount of Analyst Coverage

Mineralys Therapeutics has only been the subject of 2 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Mineralys Therapeutics are expected to grow in the coming year, from ($4.45) to ($1.92) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Mineralys Therapeutics is -6.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Mineralys Therapeutics is -6.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Mineralys Therapeutics has a P/B Ratio of 3.17. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

12.81% of the float of Mineralys Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Mineralys Therapeutics has a short interest ratio ("days to cover") of 6.36.

Change versus previous month

Short interest in Mineralys Therapeutics has recently decreased by 1.61%, indicating that investor sentiment is improving.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Mineralys Therapeutics does not currently pay a dividend.

Dividend Growth

Mineralys Therapeutics does not have a long track record of dividend growth.

News and Social Media

• Score: 2.2 / 5
• News Sentiment: 0.60

News Sentiment

Mineralys Therapeutics has a news sentiment score of 0.60. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.74 average news sentiment score of Healthcare companies.

News Coverage This Week

MarketBeat has tracked 17 news articles for Mineralys Therapeutics this week, compared to 5 articles on an average week.

Company Ownership

• Score: 2.1 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Mineralys Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $5,778,495.00 in company stock.

Percentage Held by Insiders

18.94% of the stock of Mineralys Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

84.46% of the stock of Mineralys Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

Company Calendar

• Last Earnings: 8/12/2026
• Today: 9/27/2026
• Stifel 2026 Virtual Cardiometabolic Forum: 9/30/2026
• Next Earnings (Estimated): 11/09/2026
• Fiscal Year End: 12/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Healthcare
• Industry: Pharmaceuticals
• Sub-Industry: Pharmaceuticals
• Current Symbol: NASDAQ:MLYS
• CIK: 1933414
• Web: www.mineralystx.com
• Phone: 888-378-6240
• Fax: N/A
• Employees: 76
• Year Founded: 2019

Price Target and Rating

• Average Price Target for Mineralys Therapeutics: $48.80
• High Price Target: $56.00
• Low Price Target: $30.00
• Potential Upside/Downside: +88.7%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.50
• Research Coverage: 8 Analysts

Profitability

• EPS (Trailing Twelve Months): ($4.24)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$154.65 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -57.97%
• Return on Assets: -54.15%

Debt

• Debt-to-Equity Ratio: 0.18
• Current Ratio: 34.46
• Quick Ratio: 34.46

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $8.17 per share
• Price / Book: 3.17

Miscellaneous

• Outstanding Shares: 88,407,000
• Free Float: 71,663,000
• Market Cap: $2.29 billion
• Optionable: Optionable
• Beta: 0.68