| 06/08/2026 5:23 PM | Carruthers R Michael (1644467) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 5:24 PM | GREY MICHAEL G (1240122) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 5:25 PM | Jansen Valerie Malyvanh (1889716) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 5:26 PM | OnKure Therapeutics (1637715) Issuer Phillips Andrew John (1921956) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 5:27 PM | OnKure Therapeutics (1637715) Issuer Ratcliffe Liam (1547100) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/08/2026 5:32 PM | Mathers Edward T (1328625) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/05/2026 3:15 PM | OnKure Therapeutics (1637715) Filer | Form S-8 Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans | |
| 06/04/2026 3:15 PM | OnKure Therapeutics (1637715) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 05/27/2026 3:37 PM | BIOTECHNOLOGY VALUE FUND L P (918923) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13G | |
| 05/15/2026 7:20 PM | ADAR1 Capital Management, LLC (1940272) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13G/A | |
| 05/05/2026 3:05 PM | OnKure Therapeutics (1637715) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
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| 05/04/2026 11:15 PM | OnKure Therapeutics (1637715) Filer | Form EFFECT | |
| 04/24/2026 3:03 PM | OnKure Therapeutics (1637715) Filer | Form S-3 Registration statement under Securities Act of 1933 | |
| 04/21/2026 3:15 PM | OnKure Therapeutics (1637715) Filer | Form ARS | |
| 04/21/2026 3:15 PM | OnKure Therapeutics (1637715) Filer | Form DEF 14A | |
| 04/21/2026 3:16 PM | OnKure Therapeutics (1637715) Filer | Form DEFA14A | |
| 04/07/2026 8:14 PM | AI Biotechnology LLC (1942670) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13D | |
| 04/07/2026 8:15 PM | Access Industries Holdings LLC (1391297) Reporting ACCESS INDUSTRIES MANAGEMENT, LLC (1508226) Reporting AI Biotechnology LLC (1942670) Reporting Blavatnik Len (1326628) Reporting OnKure Therapeutics (1637715) Issuer | Form 3 Initial statement of beneficial ownership of securities | |
| 04/07/2026 6:21 PM | OnKure Therapeutics (1637715) Subject StepStone Group LP (1502287) Filed by | Form SCHEDULE 13G | |
| 04/07/2026 3:30 PM | OnKure Therapeutics (1637715) Subject Trails Edge Capital Partners, LP (2077247) Filed by | Form SCHEDULE 13G | |
| 04/07/2026 3:13 PM | OnKure Therapeutics (1637715) Subject RA CAPITAL MANAGEMENT, L.P. (1346824) Filed by | Form SCHEDULE 13G | |
| 04/03/2026 2:29 PM | OnKure Therapeutics (1637715) Issuer Saccomano Nicholas A (1609284) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/03/2026 2:25 PM | Agresta Samuel (1748961) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/03/2026 2:26 PM | Hartley Dylan (2037442) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/03/2026 2:27 PM | Leverone Jason A. (1692747) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/01/2026 4:25 PM | OnKure Therapeutics (1637715) Issuer Ratcliffe Liam (1547100) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/01/2026 4:24 PM | OnKure Therapeutics (1637715) Issuer Ratcliffe Liam (1547100) Reporting | Form 3 Initial statement of beneficial ownership of securities | |
| 04/01/2026 10:17 AM | ACORN BIOVENTURES, L.P. (1766853) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13G | |
| 03/30/2026 5:01 AM | OnKure Therapeutics (1637715) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 03/24/2026 5:56 PM | Leverone Jason A. (1692747) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/24/2026 5:57 PM | OnKure Therapeutics (1637715) Issuer Saccomano Nicholas A (1609284) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/17/2026 7:15 PM | ADAR1 Capital Management, LLC (1940272) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13G | |
| 01/02/2026 3:16 PM | Mathers Edward T (1328625) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 01/02/2026 3:10 PM | Manke Isaac (1622769) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/23/2025 7:08 PM | Leverone Jason A. (1692747) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 12/23/2025 7:09 PM | OnKure Therapeutics (1637715) Issuer Saccomano Nicholas A (1609284) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 11/28/2025 7:15 AM | OnKure Therapeutics (1637715) Subject Prosight Management, LP (1617201) Filed by | Form SCHEDULE 13G | |
| 11/21/2025 3:09 PM | OnKure Therapeutics (1637715) Filer | Form 424B3 | |
| 11/18/2025 11:15 PM | OnKure Therapeutics (1637715) Filer | Form EFFECT | |
| 11/06/2025 4:25 PM | OnKure Therapeutics (1637715) Filer | Form POS AM | |
| 11/06/2025 4:08 PM | OnKure Therapeutics (1637715) Filer | Form S-3 Registration statement under Securities Act of 1933 | |
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| 11/06/2025 3:13 PM | OnKure Therapeutics (1637715) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 10/02/2025 3:29 PM | Mathers Edward T (1328625) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/24/2025 6:41 PM | Leverone Jason A. (1692747) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/24/2025 6:42 PM | OnKure Therapeutics (1637715) Issuer Saccomano Nicholas A (1609284) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/14/2025 4:28 PM | OnKure Therapeutics (1637715) Subject Samsara BioCapital, L.P. (1699737) Filed by | Form SCHEDULE 13G/A | |
| 08/14/2025 4:20 PM | OnKure Therapeutics (1637715) Subject PERCEPTIVE ADVISORS LLC (1224962) Filed by | Form SCHEDULE 13G/A | |
| 08/14/2025 3:09 PM | HIGHBRIDGE CAPITAL MANAGEMENT LLC (919185) Filed by OnKure Therapeutics (1637715) Subject | Form SCHEDULE 13G | |
| 08/12/2025 3:20 PM | OnKure Therapeutics (1637715) Filer | Form 424B3 | |
| 08/12/2025 3:20 PM | OnKure Therapeutics (1637715) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 08/12/2025 3:20 PM | OnKure Therapeutics (1637715) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 07/02/2025 3:33 PM | Mathers Edward T (1328625) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/26/2025 3:16 PM | OnKure Therapeutics (1637715) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 06/25/2025 5:52 PM | OnKure Therapeutics (1637715) Issuer Saccomano Nicholas A (1609284) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 06/25/2025 5:49 PM | Leverone Jason A. (1692747) Reporting OnKure Therapeutics (1637715) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |