| 5/19/2025 | Jane Street Group LLC | 31,198 | $174K | 0.0% | +56.0% | 0.044% | |
| 5/19/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 509,179 | $2.84M | 0.0% | +1,331.1% | 0.716% | |
| 5/16/2025 | Fred Alger Management LLC | 178,722 | $997K | 0.0% | -18.5% | 0.251% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 294,784 | $1.65M | 0.0% | +9.2% | 0.415% | |
| 5/16/2025 | Parkman Healthcare Partners LLC | 203,006 | $1.13M | 0.1% | N/A | 0.286% | |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 40,201 | $226K | 0.0% | +8.4% | 0.057% | |
| 5/16/2025 | AQR Capital Management LLC | 49,530 | $276K | 0.0% | N/A | 0.070% | |
| 5/16/2025 | Alkeon Capital Management LLC | 4,004,096 | $22.34M | 0.0% | +2.6% | 5.633% | |
| 5/15/2025 | MPM Bioimpact LLC | 1,399,514 | $7.81M | 1.3% | N/A | 1.969% | |
| 5/15/2025 | Frazier Life Sciences Management L.P. | 1,410,193 | $7.87M | 0.4% | -63.7% | 1.984% | |
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| 5/15/2025 | DAFNA Capital Management LLC | 242,000 | $1.35M | 0.4% | N/A | 0.340% | |
| 5/15/2025 | Tema Etfs LLC | 40,934 | $228K | 0.1% | -10.0% | 0.058% | |
| 5/15/2025 | Trexquant Investment LP | 76,093 | $425K | 0.0% | N/A | 0.107% | |
| 5/14/2025 | Rafferty Asset Management LLC | 77,424 | $432K | 0.0% | +50.7% | 0.109% | |
| 5/14/2025 | AlphaQuest LLC | 42,677 | $238K | 0.0% | +50.1% | 0.060% | |
| 5/14/2025 | Hsbc Holdings PLC | 17,983 | $102K | 0.0% | N/A | 0.025% | |
| 5/14/2025 | Wellington Management Group LLP | 178,217 | $994K | 0.0% | -4.4% | 0.251% | |
| 5/13/2025 | American Century Companies Inc. | 112,628 | $628K | 0.0% | +4.4% | 0.158% | |
| 5/12/2025 | Nuveen LLC | 167,502 | $935K | 0.0% | N/A | 0.236% | |
| 5/12/2025 | Invesco Ltd. | 40,419 | $226K | 0.0% | +68.7% | 0.057% | |
| 5/12/2025 | Vivo Capital LLC | 2,080,450 | $11.61M | 1.5% | +62.8% | 2.927% | |
| 5/12/2025 | Swiss National Bank | 68,400 | $382K | 0.0% | +9.6% | 0.096% | |
| 5/9/2025 | Deutsche Bank AG | 51,976 | $290K | 0.0% | -9.5% | 0.073% | |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 408,505 | $2.28M | 0.0% | -2.3% | 0.575% | |
| 5/9/2025 | Vanguard Group Inc. | 3,215,887 | $17.95M | 0.0% | +0.4% | 4.524% | |
| 5/9/2025 | PNC Financial Services Group Inc. | 11,590 | $65K | 0.0% | -14.3% | 0.016% | |
| 5/8/2025 | XTX Topco Ltd | 19,077 | $106K | 0.0% | -26.5% | 0.027% | |
| 5/7/2025 | TD Asset Management Inc | 152,700 | $852K | 0.0% | +3.3% | 0.215% | |
| 5/6/2025 | Legato Capital Management LLC | 19,523 | $109K | 0.0% | N/A | 0.027% | |
| 5/2/2025 | Victory Capital Management Inc. | 150,260 | $838K | 0.0% | +54.1% | 0.211% | |
| 5/1/2025 | New York State Common Retirement Fund | 38,486 | $215K | 0.0% | +137.1% | 0.054% | |
| 5/1/2025 | Arizona State Retirement System | 10,088 | $56K | 0.0% | N/A | 0.014% | |
| 4/10/2025 | Hennion & Walsh Asset Management Inc. | 156,643 | $874K | 0.0% | -3.8% | 0.221% | |
| 4/8/2025 | Rhumbline Advisers | 88,753 | $495K | 0.0% | -4.9% | 0.125% | |
| 3/24/2025 | Wellington Management Group LLP | 186,430 | $1.50M | 0.0% | +6.9% | 0.262% | |
| 2/18/2025 | Frazier Life Sciences Management L.P. | 3,888,238 | $31.38M | 1.3% | -6.1% | 5.510% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 35,579 | $287K | 0.0% | +54.5% | 0.050% | |
| 2/17/2025 | Two Sigma Advisers LP | 66,500 | $537K | 0.0% | +14.3% | 0.094% | |
| 2/17/2025 | Two Sigma Investments LP | 139,683 | $1.13M | 0.0% | -24.1% | 0.198% | |
| 2/17/2025 | Tema Etfs LLC | 45,476 | $367K | 0.2% | N/A | 0.064% | |
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| 2/17/2025 | Sphera Funds Management LTD. | 273,213 | $2.21M | 0.4% | +112.8% | 0.387% | |
| 2/17/2025 | Rafferty Asset Management LLC | 51,392 | $415K | 0.0% | -20.4% | 0.073% | |
| 2/17/2025 | ProShare Advisors LLC | 20,683 | $167K | 0.0% | +30.9% | 0.029% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 174,846 | $1.41M | 0.1% | +22.0% | 0.248% | |
| 2/17/2025 | NEA Management Company LLC | 1,566,081 | $12.64M | 0.7% | +4.4% | 2.219% | |
| 2/17/2025 | Millennium Management LLC | 27,634 | $223K | 0.0% | -90.6% | 0.039% | |
| 2/17/2025 | Janus Henderson Group PLC | 14,600 | $118K | 0.0% | N/A | 0.021% | |
| 2/17/2025 | Deutsche Bank AG | 57,437 | $464K | 0.0% | +48.4% | 0.081% | |
| 2/17/2025 | Cantor Fitzgerald L. P. | 22,704 | $183K | 0.0% | N/A | 0.032% | |
| 2/17/2025 | Balyasny Asset Management L.P. | 1,555,260 | $12.55M | 0.0% | +37.5% | 2.204% | |
| 2/17/2025 | Bank of America Corp DE | 112,520 | $908K | 0.0% | +34.0% | 0.159% | |
| 2/17/2025 | BNP Paribas Financial Markets | 8,801 | $71K | 0.0% | N/A | 0.012% | |
| 2/17/2025 | ArrowMark Colorado Holdings LLC | 1,395,352 | $11.26M | 0.2% | +3.0% | 1.977% | |
| 2/14/2025 | Boxer Capital Management LLC | 1,732,571 | $13.98M | 1.2% | N/A | 2.455% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 724,319 | $5.85M | 0.0% | N/A | 1.026% | |
| 2/14/2025 | Northern Trust Corp | 553,993 | $4.47M | 0.0% | +5.3% | 0.785% | |
| 2/14/2025 | Susquehanna Fundamental Investments LLC | 20,275 | $164K | 0.0% | N/A | 0.029% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 8,434 | $68K | 0.0% | -29.7% | 0.012% | |
| 2/14/2025 | Voya Investment Management LLC | 18,789 | $152K | 0.0% | -8.8% | 0.027% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 500,000 | $4.04M | 0.0% | -13.0% | 0.709% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 1,295,025 | $10.45M | 0.0% | +16.2% | 1.835% | |
| 2/14/2025 | Silverarc Capital Management LLC | 1,178,300 | $9.51M | 2.1% | +7.2% | 1.670% | |
| 2/14/2025 | Diadema Partners LP | 214,291 | $1.73M | 0.7% | N/A | 0.304% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 14,661 | $118K | 0.0% | +1,048.1% | 0.021% | |
| 2/14/2025 | MetLife Investment Management LLC | 41,608 | $336K | 0.0% | +15.3% | 0.059% | |
| 2/14/2025 | Natixis | 79,900 | $645K | 0.0% | N/A | 0.113% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 717,188 | $5.79M | 0.0% | +16.8% | 1.016% | |
| 2/13/2025 | XTX Topco Ltd | 25,966 | $210K | 0.0% | +120.9% | 0.037% | |
| 2/13/2025 | Barclays PLC | 114,692 | $927K | 0.0% | +6.9% | 0.163% | |
| 2/13/2025 | Legal & General Group Plc | 32,928 | $266K | 0.0% | -14.2% | 0.047% | |
| 2/13/2025 | Invesco Ltd. | 23,958 | $193K | 0.0% | +8.5% | 0.034% | |
| 2/13/2025 | Wells Fargo & Company MN | 35,857 | $289K | 0.0% | +30.2% | 0.051% | |
| 2/12/2025 | ExodusPoint Capital Management LP | 23,417 | $189K | 0.0% | N/A | 0.033% | |
| 2/12/2025 | Geode Capital Management LLC | 1,278,713 | $10.32M | 0.0% | +0.4% | 1.812% | |
| 2/12/2025 | Alliancebernstein L.P. | 53,870 | $435K | 0.0% | -12.9% | 0.076% | |
| 2/12/2025 | Wellington Management Group LLP | 186,430 | $1.50M | 0.0% | +6.9% | 0.264% | |
| 2/12/2025 | NEOS Investment Management LLC | 45,476 | $367K | 0.0% | N/A | 0.064% | |
| 2/12/2025 | JPMorgan Chase & Co. | 33,736 | $272K | 0.0% | -4.3% | 0.048% | |
| 2/11/2025 | Corebridge Financial Inc. | 30,610 | $247K | 0.0% | -7.0% | 0.043% | |
| 2/11/2025 | Vanguard Group Inc. | 3,203,789 | $25.86M | 0.0% | +1.2% | 4.540% | |
| 2/11/2025 | KLP Kapitalforvaltning AS | 6,200 | $50K | 0.0% | N/A | 0.009% | |
| 2/11/2025 | American Century Companies Inc. | 107,862 | $870K | 0.0% | +8.4% | 0.153% | |
| 2/10/2025 | Monaco Asset Management SAM | 135,561 | $1.09M | 0.2% | -10.0% | 0.192% | |
| 2/10/2025 | Swiss National Bank | 62,400 | $504K | 0.0% | +5.4% | 0.088% | |
| 2/7/2025 | AlphaQuest LLC | 28,435 | $229K | 0.0% | +2,597.8% | 0.040% | |
| 2/7/2025 | PNC Financial Services Group Inc. | 13,517 | $109K | 0.0% | +22.9% | 0.019% | |
| 2/6/2025 | M&T Bank Corp | 99,234 | $801K | 0.0% | +16.6% | 0.141% | |
| 2/6/2025 | Victory Capital Management Inc. | 97,500 | $787K | 0.0% | -2.3% | 0.138% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 417,955 | $3.37M | 0.0% | +1.9% | 0.592% | |
| 1/30/2025 | Rhumbline Advisers | 93,319 | $753K | 0.0% | +4.6% | 0.132% | |
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| 1/24/2025 | China Universal Asset Management Co. Ltd. | 14,963 | $121K | 0.0% | +10.3% | 0.021% | |
| 1/17/2025 | SG Americas Securities LLC | 66,364 | $536K | 0.0% | -4.7% | 0.094% | |
| 1/15/2025 | Hennion & Walsh Asset Management Inc. | 162,909 | $1.32M | 0.1% | +18.1% | 0.231% | |
| 12/26/2024 | JPMorgan Chase & Co. | 35,251 | $361K | 0.0% | +3.8% | 0.050% | |
| 11/27/2024 | Franklin Resources Inc. | 950,459 | $9.07M | 0.0% | +26.1% | 1.347% | |
| 11/19/2024 | Barclays PLC | 107,261 | $1.10M | 0.0% | +111.2% | 0.152% | |
| 11/16/2024 | Geode Capital Management LLC | 1,273,513 | $13.06M | 0.0% | +4.2% | 1.805% | |
| 11/15/2024 | M&T Bank Corp | 85,137 | $873K | 0.0% | +19.2% | 0.121% | |
| 11/15/2024 | Barclays PLC | 107,261 | $1.10M | 0.0% | +111.2% | 0.152% | |
| 11/15/2024 | XTX Topco Ltd | 11,757 | $121K | 0.0% | -45.7% | 0.017% | |
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