NASDAQ:STOK Stoke Therapeutics (STOK) Stock Price, News & Analysis $19.69 +0.39 (+2.02%) As of 03:23 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock About Stoke Therapeutics Stock (NASDAQ:STOK) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Stoke Therapeutics alerts:Sign Up Key Stats Today's Range$19.07▼$19.9750-Day Range$11.35▼$19.6852-Week Range$5.35▼$19.97Volume352,783 shsAverage Volume805,489 shsMarket Capitalization$1.08 billionP/E Ratio23.11Dividend YieldN/APrice Target$25.57Consensus RatingBuy Company Overview Stoke Therapeutics, Inc., an early-stage biopharmaceutical company, develops medicines to treat the underlying causes of severe genetic diseases in the United States. The company utilizes its proprietary targeted augmentation of nuclear gene output to develop antisense oligonucleotides to selectively restore protein levels. Its lead clinical candidate is STK-002, which is in preclinical stage for the treatment of autosomal dominant optic atrophy. The company also develops STK-001, which is in phase I/II clinical trial to treat Dravet syndrome; and programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye. The company has a license and collaboration agreement with Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of severe and rare genetic neurodevelopmental diseases of the central nervous system. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts. Read More Stoke Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks90th Percentile Overall ScoreSTOK MarketRank™: Stoke Therapeutics scored higher than 90% of companies evaluated by MarketBeat, and ranked 125th out of 949 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.6 / 5Analyst RatingBuy Consensus RatingStoke Therapeutics has received a consensus rating of Buy. The company's average rating score is 3.22, and is based on 7 buy ratings, no hold ratings, and no sell ratings.Amount of Analyst CoverageStoke Therapeutics has been the subject of 5 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Stoke Therapeutics' stock forecast and price target. Earnings and Valuation1.3 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Stoke Therapeutics are expected to decrease in the coming year, from ($2.01) to ($2.27) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Stoke Therapeutics is 23.11, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 28.70.Price to Earnings Ratio vs. SectorThe P/E ratio of Stoke Therapeutics is 23.11, which means that it is trading at a less expensive P/E ratio than the Medical sector average P/E ratio of about 31.31.Price to Book Value per Share RatioStoke Therapeutics has a P/B Ratio of 3.22. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Stoke Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted23.13% of the float of Stoke Therapeutics has been sold short.Short Interest Ratio / Days to CoverStoke Therapeutics has a short interest ratio ("days to cover") of 17.5, which indicates bearish sentiment.Change versus previous monthShort interest in Stoke Therapeutics has recently decreased by 0.61%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldStoke Therapeutics does not currently pay a dividend.Dividend GrowthStoke Therapeutics does not have a long track record of dividend growth. Sustainability and ESG4.8 / 5Environmental Score-0.59 Percentage of Shares Shorted23.13% of the float of Stoke Therapeutics has been sold short.Short Interest Ratio / Days to CoverStoke Therapeutics has a short interest ratio ("days to cover") of 17.5, which indicates bearish sentiment.Change versus previous monthShort interest in Stoke Therapeutics has recently decreased by 0.61%, indicating that investor sentiment is improving. News and Social Media2.1 / 5News Sentiment0.84 News SentimentStoke Therapeutics has a news sentiment score of 0.84. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.99 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 5 news articles for Stoke Therapeutics this week, compared to 6 articles on an average week.Search Interest15 people have searched for STOK on MarketBeat in the last 30 days. This is an increase of 67% compared to the previous 30 days.MarketBeat FollowsOnly 2 people have added Stoke Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -82% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Stoke Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $345,775.00 in company stock.Percentage Held by InsidersOnly 9.50% of the stock of Stoke Therapeutics is held by insiders.Read more about Stoke Therapeutics' insider trading history. Receive STOK Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Stoke Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. STOK Stock News HeadlinesInsider Selling: Stoke Therapeutics, Inc. (NASDAQ:STOK) General Counsel Sells 13,712 Shares of StockAugust 16, 2025 | insidertrades.comStoke Therapeutics: Vulnerable To Profit TakingAugust 27 at 10:06 AM | seekingalpha.comElon’s BIGGEST warning yet?Tesla's About to Prove Everyone Wrong... Again Back in 2018, when Jeff Brown told everyone to buy Tesla… The "experts" said Elon was finished and Tesla was headed for bankruptcy. Now they're saying the same thing, but Jeff has uncovered Tesla's next breakthrough.August 28 at 2:00 AM | Brownstone Research (Ad)Stoke Therapeutics price target lowered to $28 from $29 at BTIGAugust 18, 2025 | msn.comSHAREHOLDER ALERT: Purcell & Lefkowitz LLP Announces Shareholder Investigation of Stoke Therapeutics, Inc. (NASDAQ: STOK)August 18, 2025 | prnewswire.comFY2025 Earnings Estimate for STOK Issued By Chardan CapitalAugust 18, 2025 | americanbankingnews.comLeerink Partnrs Has Optimistic Outlook of STOK Q3 EarningsAugust 17, 2025 | americanbankingnews.comHC Wainwright Issues Optimistic Forecast for STOK EarningsAugust 17, 2025 | americanbankingnews.comSee More Headlines STOK Stock Analysis - Frequently Asked Questions How have STOK shares performed this year? Stoke Therapeutics' stock was trading at $11.03 at the beginning of the year. Since then, STOK stock has increased by 78.5% and is now trading at $19.69. How were Stoke Therapeutics' earnings last quarter? Stoke Therapeutics, Inc. (NASDAQ:STOK) announced its quarterly earnings results on Tuesday, August, 12th. The company reported ($0.40) earnings per share for the quarter, topping analysts' consensus estimates of ($0.57) by $0.17. The business earned $13.82 million during the quarter, compared to the consensus estimate of $31.51 million. Stoke Therapeutics had a trailing twelve-month return on equity of 18.32% and a net margin of 26.25%. Read the conference call transcript. When did Stoke Therapeutics IPO? Stoke Therapeutics (STOK) raised $100 million in an IPO on Wednesday, June 19th 2019. The company issued 6,700,000 shares at $14.00-$16.00 per share. J.P. Morgan, Cowen and Credit Suisse served as the underwriters for the IPO and Canaccord Genuity was co-manager. Who are Stoke Therapeutics' major shareholders? Stoke Therapeutics' top institutional shareholders include Redmile Group LLC (8.01%), Skorpios Trust (5.96%), Marshall Wace LLP (4.21%) and Geode Capital Management LLC (1.78%). Insiders that own company stock include Skorpios Trust, Edward M Md Kaye, Stephen J Tulipano, Jonathan Allan and Barry Ticho. View institutional ownership trends. How do I buy shares of Stoke Therapeutics? Shares of STOK stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Stoke Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Stoke Therapeutics investors own include Enovix (ENVX), Rambus (RMBS), COMPASS Pathways (CMPS), Globant (GLOB), Ginkgo Bioworks (DNA), Toast (TOST) and Saia (SAIA). Company Calendar Last Earnings8/12/2025Today8/28/2025Next Earnings (Estimated)11/04/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:STOK CIK1623526 Webwww.stoketherapeutics.com Phone(781) 430-8200FaxN/AEmployees100Year FoundedN/APrice Target and Rating Average Price Target for Stoke Therapeutics$25.57 High Price Target$35.00 Low Price Target$18.00 Potential Upside/Downside+32.5%Consensus RatingBuy Rating Score (0-4)3.22 Research Coverage9 Analysts Profitability EPS (Trailing Twelve Months)$0.85 Trailing P/E Ratio22.71 Forward P/E RatioN/A P/E GrowthN/ANet Income-$88.98 million Net Margins26.25% Pretax Margin26.90% Return on Equity18.32% Return on Assets15.48% Debt Debt-to-Equity RatioN/A Current Ratio6.98 Quick Ratio6.98 Sales & Book Value Annual Sales$36.56 million Price / Sales28.93 Cash FlowN/A Price / Cash FlowN/A Book Value$6.11 per share Price / Book3.16Miscellaneous Outstanding Shares54,800,000Free Float49,591,000Market Cap$1.06 billion OptionableOptionable Beta1.15 Social Links (Almost) Everything You Need To Know About The EV MarketLooking to profit from the electric vehicle mega-trend? 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