NASDAQ:STOK Stoke Therapeutics (STOK) Stock Price, News & Analysis $31.11 +0.14 (+0.45%) As of 06/23/2026 04:00 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Stoke Therapeutics Stock (NASDAQ:STOK) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Stoke Therapeutics alerts:Sign Up Key Stats Today's Range$30.74▼$32.3650-Day Range$28.48▼$37.2752-Week Range$11.17▼$40.22Volume1.18 million shsAverage Volume577,291 shsMarket Capitalization$1.94 billionP/E RatioN/ADividend YieldN/APrice Target$41.83Consensus RatingModerate Buy Company Overview Stoke Therapeutics, headquartered in Bedford, Massachusetts, is a clinical-stage biopharmaceutical company focused on developing genetic medicines to upregulate protein production for the treatment of rare neuromuscular and neurological disorders. Founded in 2014, the company applies its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO™) platform to design antisense oligonucleotides that selectively modulate RNA splicing and enhance expression of functional proteins. The company’s lead program, STK-001, is an antisense oligonucleotide therapy designed to increase production of the sodium channel protein SCN1A and is currently in clinical development for Dravet syndrome, a severe childhood-onset epilepsy. In addition to STK-001, Stoke is advancing STK-002, its preclinical candidate for spinocerebellar ataxia type 6 (SCA6), along with other discovery-stage programs targeting genetic diseases characterized by insufficient protein levels. Stoke’s approach aims to address the underlying genetic deficiency rather than solely treating symptoms, positioning its pipeline to potentially benefit a range of patient populations with high unmet medical needs. Since going public on the Nasdaq exchange in early 2020, Stoke Therapeutics has grown its research capabilities and established strategic collaborations to support its development efforts. The company’s leadership team brings together expertise in molecular biology, neurology and clinical development, guiding Stoke’s mission to translate its TANGO platform into transformative therapies. Stoke serves patient communities and clinical partners globally, with ongoing and planned trials conducted across North America and Europe.AI Generated. May Contain Errors. Read More Stoke Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks50th Percentile Overall ScoreSTOK MarketRank™: Stoke Therapeutics scored higher than 50% of companies evaluated by MarketBeat, and ranked 452nd out of 850 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.8 / 5Analyst RatingModerate Buy Consensus RatingStoke Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.73, and is based on no strong buy ratings, 9 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialStoke Therapeutics has a consensus price target of $41.83, representing about 34.5% upside from its current price of $31.11.Amount of Analyst CoverageStoke Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Stoke Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Stoke Therapeutics are expected to grow in the coming year, from ($3.22) to ($2.90) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Stoke Therapeutics is -11.07, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Stoke Therapeutics is -11.07, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioStoke Therapeutics has a P/B Ratio of 5.04. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Stoke Therapeutics' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted19.92% of the float of Stoke Therapeutics has been sold short.Short Interest Ratio / Days to CoverStoke Therapeutics has a short interest ratio ("days to cover") of 19.13, which indicates bearish sentiment.Change versus previous monthShort interest in Stoke Therapeutics has recently decreased by 13.09%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldStoke Therapeutics does not currently pay a dividend.Dividend GrowthStoke Therapeutics does not have a long track record of dividend growth. News and Social Media1.6 / 5News Sentiment0.64 News SentimentStoke Therapeutics has a news sentiment score of 0.64. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Medical companies.News Coverage This WeekMarketBeat has tracked 4 news articles for Stoke Therapeutics this week, compared to 5 articles on an average week.MarketBeat FollowsOnly 1 people have added Stoke Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership1.1 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Stoke Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $98,528.00 in company stock.Percentage Held by Insiders9.50% of the stock of Stoke Therapeutics is held by insiders.Percentage Held by InstitutionsStoke Therapeutics has minimal institutional ownership at this time.Read more about Stoke Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. STOK Stock News HeadlinesStoke Therapeutics (NASDAQ:STOK) General Counsel Sells $43,637.15 in StockJune 21 at 4:42 AM | americanbankingnews.comJonathan Allan Sells 1,457 Shares of Stoke Therapeutics (NASDAQ:STOK) StockJune 19, 2026 | insidertrades.comThe Treasury just bought its own debtOn April 16th, the U.S. Treasury executed a $15 billion buyback of its own debt - the largest in history - while former Treasury Secretary Hank Paulson publicly warned of collapsing demand for U.S. bonds. According to Garrett Goggin, CFA, CMT, with 20 years studying gold and debt cycles, this is the moment miners priced for a world that no longer exists stand to benefit most. As natural bond buyers disappear and the Fed steps in, the move in gold may only be beginning. | Golden Portfolio (Ad)Stoke Therapeutics, Inc. (NASDAQ:STOK) Receives Average Recommendation of "Moderate Buy" from AnalystsJune 15, 2026 | americanbankingnews.comStoke Therapeutics, Inc. (STOK) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 TranscriptJune 8, 2026 | seekingalpha.comStoke Therapeutics Stockholders Approve Directors and Governance ItemsJune 4, 2026 | tipranks.comBarry Ticho Sells 1,795 Shares of Stoke Therapeutics (NASDAQ:STOK) StockJune 4, 2026 | insidertrades.comStoke Therapeutics, Inc. (STOK) Reports Q1 Results and Business UpdatesJune 1, 2026 | insidermonkey.comSee More Headlines STOK Stock Analysis - Frequently Asked Questions How have STOK shares performed this year? Stoke Therapeutics' stock was trading at $31.74 at the start of the year. Since then, STOK stock has decreased by 2.0% and is now trading at $31.11. How were Stoke Therapeutics' earnings last quarter? Stoke Therapeutics, Inc. (NASDAQ:STOK) announced its earnings results on Thursday, May, 7th. The company reported ($0.79) earnings per share (EPS) for the quarter, topping analysts' consensus estimates of ($0.80) by $0.01. The company earned $6.23 million during the quarter, compared to the consensus estimate of $6.48 million. Stoke Therapeutics had a negative trailing twelve-month return on equity of 48.84% and a negative net margin of 529.20%. Read the conference call transcript. When did Stoke Therapeutics IPO? Stoke Therapeutics (STOK) raised $118 million in an IPO on Wednesday, June 19th 2019. The company issued 7,891,110 shares at $14.00-$16.00 per share. J.P. Morgan, Cowen and Credit Suisse acted as the underwriters for the IPO and Canaccord Genuity was co-manager. Who are Stoke Therapeutics' major shareholders? Stoke Therapeutics' top institutional shareholders include Redmile Group LLC (6.69%), Siren L.L.C. (3.20%), Janus Henderson Group PLC (2.59%) and Dimensional Fund Advisors LP (1.59%). Insiders that own company stock include Skorpios Trust, Adrian R Krainer, Edward M Md Kaye, Barry Ticho, Arthur Tzianabos, Stephen J Tulipano, Jonathan Allan, Jason Hoitt, Thomas Leggett and Arthur A Levin. View institutional ownership trends. How do I buy shares of Stoke Therapeutics? Shares of STOK stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Stoke Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Stoke Therapeutics investors own include Enovix (ENVX), Rambus (RMBS), Compass Pathways (CMPS), Globant (GLOB), Ginkgo Bioworks (DNA), Toast (TOST) and Saia (SAIA). Company Calendar Last Earnings5/07/2026Today6/23/2026Next Earnings (Estimated)8/11/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (7m+) 1-Year History Jun 25 Sep 25 Dec 25 Mar 26 Jun 26 STOK's financial health is in the Green zone, according to TradeSmith. STOK has been in this zone for over 7 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:STOK CIK1623526 Webwww.stoketherapeutics.com Phone(781) 430-8200FaxN/AEmployees100Year Founded2014Price Target and Rating Average Price Target for Stoke Therapeutics$41.83 High Price Target$60.00 Low Price Target$25.00 Potential Upside/Downside+34.5%Consensus RatingModerate Buy Rating Score (0-4)2.73 Research Coverage11 Analysts Profitability EPS (Trailing Twelve Months)($2.81) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$6.89 million Net Margins-529.20% Pretax Margin-533.18% Return on Equity-48.84% Return on Assets-42.27% Debt Debt-to-Equity RatioN/A Current Ratio8.99 Quick Ratio8.99 Sales & Book Value Annual Sales$184.42 million Price / Sales10.51 Cash FlowN/A Price / Cash FlowN/A Book Value$6.17 per share Price / Book5.04Miscellaneous Outstanding Shares62,280,000Free Float56,365,000Market Cap$1.94 billion OptionableOptionable Beta1.17 Social Links 5G Stocks: The Path Forward is ProfitableClick the link to see MarketBeat's guide to investing in 5G and which 5G stocks show the most promise. 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