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Talphera (TLPH) Competitors

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$0.85 +0.07 (+9.26%)
Closing price 06/8/2026 04:00 PM Eastern
Extended Trading
$0.85 +0.01 (+0.61%)
As of 06/8/2026 07:59 PM Eastern
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TLPH vs. SPRO, PLX, MOLN, ORMP, and OGI

Should you buy Talphera stock or one of its competitors? MarketBeat compares Talphera with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Talphera include Spero Therapeutics (SPRO), Protalix BioTherapeutics (PLX), Molecular Partners (MOLN), Oramed Pharmaceuticals (ORMP), and Organigram Global (OGI). These companies are all part of the "pharmaceutical products" industry.

How does Talphera compare to Spero Therapeutics?

Talphera (NASDAQ:TLPH) and Spero Therapeutics (NASDAQ:SPRO) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, dividends, valuation, earnings, analyst recommendations, media sentiment, risk and institutional ownership.

Talphera has a beta of 0.76, meaning that its stock price is 24% less volatile than the broader market. Comparatively, Spero Therapeutics has a beta of 1.45, meaning that its stock price is 45% more volatile than the broader market.

In the previous week, Talphera had 7 more articles in the media than Spero Therapeutics. MarketBeat recorded 7 mentions for Talphera and 0 mentions for Spero Therapeutics. Talphera's average media sentiment score of 0.90 beat Spero Therapeutics' score of 0.00 indicating that Talphera is being referred to more favorably in the media.

Company Overall Sentiment
Talphera Positive
Spero Therapeutics Neutral

37.7% of Talphera shares are owned by institutional investors. Comparatively, 25.6% of Spero Therapeutics shares are owned by institutional investors. 3.5% of Talphera shares are owned by insiders. Comparatively, 2.9% of Spero Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Spero Therapeutics has a net margin of 24.90% compared to Talphera's net margin of 0.00%. Spero Therapeutics' return on equity of 35.58% beat Talphera's return on equity.

Company Net Margins Return on Equity Return on Assets
TalpheraN/A -92.98% -53.22%
Spero Therapeutics 24.90%35.58%24.95%

Talphera presently has a consensus price target of $3.00, indicating a potential upside of 254.27%. Given Talphera's stronger consensus rating and higher probable upside, analysts plainly believe Talphera is more favorable than Spero Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Talphera
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Spero Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

Spero Therapeutics has higher revenue and earnings than Talphera. Talphera is trading at a lower price-to-earnings ratio than Spero Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Talphera$30K1,464.96-$14.29M-$0.31N/A
Spero Therapeutics$66.80M2.37$8.57M$0.2411.42

Summary

Talphera and Spero Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Talphera compare to Protalix BioTherapeutics?

Talphera (NASDAQ:TLPH) and Protalix BioTherapeutics (NYSE:PLX) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, institutional ownership, dividends, analyst recommendations, profitability, valuation, risk and media sentiment.

Talphera has a beta of 0.76, meaning that its share price is 24% less volatile than the broader market. Comparatively, Protalix BioTherapeutics has a beta of -0.02, meaning that its share price is 102% less volatile than the broader market.

Talphera has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Talphera's return on equity.

Company Net Margins Return on Equity Return on Assets
TalpheraN/A -92.98% -53.22%
Protalix BioTherapeutics -21.03%-30.89%-11.74%

Protalix BioTherapeutics has higher revenue and earnings than Talphera. Talphera is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Talphera$30K1,464.96-$14.29M-$0.31N/A
Protalix BioTherapeutics$76.38M2.07$8.31M$0.1810.89

In the previous week, Talphera had 6 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 7 mentions for Talphera and 1 mentions for Protalix BioTherapeutics. Talphera's average media sentiment score of 0.90 beat Protalix BioTherapeutics' score of 0.00 indicating that Talphera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Talphera
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protalix BioTherapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Talphera currently has a consensus target price of $3.00, indicating a potential upside of 254.27%. Protalix BioTherapeutics has a consensus target price of $12.00, indicating a potential upside of 512.24%. Given Protalix BioTherapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Protalix BioTherapeutics is more favorable than Talphera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Talphera
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00

37.7% of Talphera shares are owned by institutional investors. Comparatively, 16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 3.5% of Talphera shares are owned by company insiders. Comparatively, 6.5% of Protalix BioTherapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

Talphera and Protalix BioTherapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Talphera compare to Molecular Partners?

Talphera (NASDAQ:TLPH) and Molecular Partners (NASDAQ:MOLN) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, media sentiment, profitability, analyst recommendations, risk, valuation and dividends.

Talphera has a beta of 0.76, indicating that its share price is 24% less volatile than the broader market. Comparatively, Molecular Partners has a beta of 1.07, indicating that its share price is 7% more volatile than the broader market.

In the previous week, Talphera had 7 more articles in the media than Molecular Partners. MarketBeat recorded 7 mentions for Talphera and 0 mentions for Molecular Partners. Talphera's average media sentiment score of 0.90 beat Molecular Partners' score of 0.00 indicating that Talphera is being referred to more favorably in the media.

Company Overall Sentiment
Talphera Positive
Molecular Partners Neutral

Talphera presently has a consensus price target of $3.00, indicating a potential upside of 254.27%. Molecular Partners has a consensus price target of $8.38, indicating a potential upside of 100.36%. Given Talphera's stronger consensus rating and higher possible upside, equities analysts clearly believe Talphera is more favorable than Molecular Partners.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Talphera
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Molecular Partners
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Talphera has higher earnings, but lower revenue than Molecular Partners. Talphera is trading at a lower price-to-earnings ratio than Molecular Partners, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Talphera$30K1,464.96-$14.29M-$0.31N/A
Molecular Partners$5.65M29.87-$74.41M-$1.94N/A

37.7% of Talphera shares are owned by institutional investors. Comparatively, 26.6% of Molecular Partners shares are owned by institutional investors. 3.5% of Talphera shares are owned by insiders. Comparatively, 5.9% of Molecular Partners shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Molecular Partners' return on equity of -66.62% beat Talphera's return on equity.

Company Net Margins Return on Equity Return on Assets
TalpheraN/A -92.98% -53.22%
Molecular Partners N/A -66.62%-54.85%

Summary

Talphera beats Molecular Partners on 9 of the 14 factors compared between the two stocks.

How does Talphera compare to Oramed Pharmaceuticals?

Talphera (NASDAQ:TLPH) and Oramed Pharmaceuticals (NASDAQ:ORMP) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, media sentiment, earnings, institutional ownership, dividends, analyst recommendations, valuation and risk.

In the previous week, Talphera had 6 more articles in the media than Oramed Pharmaceuticals. MarketBeat recorded 7 mentions for Talphera and 1 mentions for Oramed Pharmaceuticals. Talphera's average media sentiment score of 0.90 beat Oramed Pharmaceuticals' score of 0.00 indicating that Talphera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Talphera
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Oramed Pharmaceuticals
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Oramed Pharmaceuticals has higher revenue and earnings than Talphera. Talphera is trading at a lower price-to-earnings ratio than Oramed Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Talphera$30K1,464.96-$14.29M-$0.31N/A
Oramed Pharmaceuticals$2M74.49$64.05M$2.591.41

Talphera has a beta of 0.76, suggesting that its share price is 24% less volatile than the broader market. Comparatively, Oramed Pharmaceuticals has a beta of 1.26, suggesting that its share price is 26% more volatile than the broader market.

37.7% of Talphera shares are owned by institutional investors. Comparatively, 12.7% of Oramed Pharmaceuticals shares are owned by institutional investors. 3.5% of Talphera shares are owned by company insiders. Comparatively, 17.8% of Oramed Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Oramed Pharmaceuticals' return on equity of -5.37% beat Talphera's return on equity.

Company Net Margins Return on Equity Return on Assets
TalpheraN/A -92.98% -53.22%
Oramed Pharmaceuticals N/A -5.37%-4.83%

Talphera presently has a consensus price target of $3.00, indicating a potential upside of 254.27%. Given Talphera's stronger consensus rating and higher possible upside, equities analysts plainly believe Talphera is more favorable than Oramed Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Talphera
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Oramed Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Oramed Pharmaceuticals beats Talphera on 8 of the 15 factors compared between the two stocks.

How does Talphera compare to Organigram Global?

Organigram Global (NASDAQ:OGI) and Talphera (NASDAQ:TLPH) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, dividends, risk, analyst recommendations, earnings, valuation, profitability and institutional ownership.

34.6% of Organigram Global shares are held by institutional investors. Comparatively, 37.7% of Talphera shares are held by institutional investors. 0.1% of Organigram Global shares are held by insiders. Comparatively, 3.5% of Talphera shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Talphera has lower revenue, but higher earnings than Organigram Global. Organigram Global is trading at a lower price-to-earnings ratio than Talphera, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Organigram Global$185.07M0.81-$17.70M-$0.13N/A
Talphera$30K1,464.96-$14.29M-$0.31N/A

Organigram Global has a beta of 1.43, meaning that its stock price is 43% more volatile than the broader market. Comparatively, Talphera has a beta of 0.76, meaning that its stock price is 24% less volatile than the broader market.

Talphera has a net margin of 0.00% compared to Organigram Global's net margin of -9.22%. Organigram Global's return on equity of -13.41% beat Talphera's return on equity.

Company Net Margins Return on Equity Return on Assets
Organigram Global-9.22% -13.41% -9.09%
Talphera N/A -92.98%-53.22%

Talphera has a consensus target price of $3.00, indicating a potential upside of 254.27%. Given Talphera's higher possible upside, analysts plainly believe Talphera is more favorable than Organigram Global.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Organigram Global
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Talphera
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

In the previous week, Talphera had 7 more articles in the media than Organigram Global. MarketBeat recorded 7 mentions for Talphera and 0 mentions for Organigram Global. Talphera's average media sentiment score of 0.90 beat Organigram Global's score of 0.00 indicating that Talphera is being referred to more favorably in the news media.

Company Overall Sentiment
Organigram Global Neutral
Talphera Positive

Summary

Talphera beats Organigram Global on 9 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding TLPH and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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TLPH vs. The Competition

MetricTalpheraMED IndustryMedical SectorNASDAQ Exchange
Market Cap$40.22M$2.96B$6.49B$11.99B
Dividend YieldN/A1.70%2.67%5.57%
P/E Ratio-2.7317.6823.6823.74
Price / Sales1,464.96286.81507.33108.39
Price / CashN/A56.1726.9937.25
Price / Book2.293.8310.286.78
Net Income-$14.29M$75.85M$3.57B$337.51M
7 Day Performance9.22%-2.00%0.28%-2.34%
1 Month Performance-6.30%-5.85%3.27%1.88%
1 Year Performance64.40%14.03%22.22%25.55%

Talphera Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
TLPH
Talphera
4.0135 of 5 stars
$0.85
+9.3%
$3.00
+254.3%
+66.0%$40.22M$30KN/A19
SPRO
Spero Therapeutics
1.0193 of 5 stars
$2.83
flat
N/A+9.6%$163.86M$66.80M11.79150
PLX
Protalix BioTherapeutics
2.5646 of 5 stars
$2.00
-3.2%
$12.00
+501.5%
+24.1%$160.74M$76.38MN/A200
MOLN
Molecular Partners
3.2467 of 5 stars
$3.92
-0.8%
$8.38
+113.6%
+13.6%$159.48M$5.65MN/A180
ORMP
Oramed Pharmaceuticals
1.749 of 5 stars
$3.60
-7.5%
N/A+64.0%$159.20M$2M1.3910

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This page (NASDAQ:TLPH) was last updated on 6/9/2026 by MarketBeat.com Staff.
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