NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $32.69 +0.04 (+0.12%) Closing price 08/1/2025 04:10 PM EasternExtended Trading$32.41 -0.28 (-0.86%) As of 08/1/2025 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SBIO alerts:Sign Up Key Stats Today's Range$32.41▼$32.7450-Day Range$28.23▼$33.5052-Week Range$22.33▼$42.73Volume4,715 shsAverage Volume14,564 shsMarket Capitalization$78.46 millionAssets Under Management$76.84 millionDividend Yield3.58%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.56%0.56%0.51%0.53%Other Expenses0.00%0.47%0.56%0.59%0.56%Total Expense0.50%0.75%0.76%0.74%0.73%Fee Waiver0.00%-0.67%-0.66%-0.71%-0.63%Net Expense0.50%0.60%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Email Address SBIO ETF News HeadlinesALPS MEDICAL BREAKTHROUGHS ETF ETFs - Markets InsiderJuly 3, 2025 | markets.businessinsider.comSBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tariffs just lit the fuse. Millions of investors are blindsided as stocks plunge… but this is only Phase 1. If you're still holding the wrong assets, you could lose 30% or more in the coming weeks. | American Alternative (Ad)Advacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comWhy Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comALPS Medical Breakthroughs ETF (^SBIO-IV)July 19, 2024 | finance.yahoo.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 at the start of the year. Since then, SBIO shares have decreased by 1.0% and is now trading at $32.69. Who are ALPS Medical Breakthroughs ETF's major shareholders? ALPS Medical Breakthroughs ETF's top institutional investors include DAVENPORT & Co LLC (28.57%), Strategic Financial Services Inc. (1.58%), NTV Asset Management LLC (0.85%) and Moran Wealth Management LLC (0.42%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AU Optronics (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings109 Fund Statistics Assets Under Management$76.84 million Average Daily Volume$6.14 thousand Discount/Premium-0.01% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume3 Put Options8 Call Options3 Short Interest16,100 shs Miscellaneous Outstanding Shares2,400,000Beta0.92 Creation Unit50,000 Creation Fee$500.00 7 Stocks That Could Be Bigger Than Tesla, Nvidia, and GoogleLooking for the next FAANG stock before everyone has heard about it? Enter your email address to see which stocks MarketBeat analysts think might become the next trillion dollar tech company.Get This Free Report Top 10 SBIO HoldingsRhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 3.46%Axsome Therapeutics (NASDAQ:AXSM)Holding Weight: 3.38%Nuvalent (NASDAQ:NUVL)Holding Weight: 3.38%Alkermes (NASDAQ:ALKS)Holding Weight: 3.14%Vaxcyte (NASDAQ:PCVX)Holding Weight: 2.92%Cytokinetics (NASDAQ:CYTK)Holding Weight: 2.78%Krystal Biotech (NASDAQ:KRYS)Holding Weight: 2.68%Metsera (NASDAQ:MTSR)Holding Weight: 2.60%Akero Therapeutics (NASDAQ:AKRO)Holding Weight: 2.58%Merus (NASDAQ:MRUS)Holding Weight: 2.55%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 8/4/2025 by MarketBeat.com Staff From Our PartnersTrump set to Boost Social Security Checks by 400%?If you're collecting or planning to collect social security... You should see this presentation about Presi...InvestorPlace | SponsoredWall Street Laughed. 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