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SPDR S&P Pharmaceuticals ETF (XPH) Holdings List

SPDR S&P Pharmaceuticals ETF logo
$70.98 +1.00 (+1.43%)
As of 08/14/2026 04:10 PM Eastern

What stocks does XPH hold?

The SPDR S&P Pharmaceuticals ETF (XPH) top stock holdings include Crinetics Pharmaceuticals, MBX Biosciences, and Definium Therapeutics. The top 25 XPH holdings ordered by weight make up 51.36% of the total fund. XPH is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XPH stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XPH Holdings

RankCompanyCurrent PriceWeightShares Held
1
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$84.70
+0.3%
3.59%215,959
2
MBX Biosciences, Inc. stock logo
MBX
MBX Biosciences
$68.57
+2.2%
3.16%239,167
3
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$42.63
-2.9%
2.82%318,922
4
Atai Beckley N.V. stock logo
ATAI
Atai Beckley
$7.26
+0.1%
2.80%1,960,781
5
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$21.63
-3.8%
2.27%550,650
6
Corcept Therapeutics Incorporated stock logo
CORT
Corcept Therapeutics
$114.47
+3.6%
2.23%94,878
7
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$6.24
+2.2%
2.16%1,618,286
8
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$58.82
+1.3%
2.15%200,318
9
Alumis Inc. stock logo
ALMS
Alumis
$25.31
+3.7%
2.13%369,478
10
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$18.46
+1.7%
2.03%553,115
11
Liquidia Corporation stock logo
LQDA
Liquidia
$74.44
+3.2%
1.96%113,591
12
Nektar Therapeutics stock logo
NKTR
Nektar Therapeutics
$73.02
-3.8%
1.86%130,532
13
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$44.17
+2.3%
1.84%225,144
14
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$18.15
+5.1%
1.78%483,794
15
Ligand Pharmaceuticals Incorporated stock logo
LGND
Ligand Pharmaceuticals
$294.60
+2.0%
1.76%29,860
16
Omeros Corporation stock logo
OMER
Omeros
$17.19
-0.9%
1.73%726,641
17
Bristol Myers Squibb Company stock logo
BMY
Bristol Myers Squibb
$63.86
-1.2%
1.72%133,305
18
Eton Pharmaceuticals, Inc. stock logo
ETON
Eton Pharmaceuticals
$58.86
+44.3%
1.71%175,076
19
Elanco Animal Health Incorporated stock logo
ELAN
Elanco Animal Health
$23.64
+5.0%
1.71%324,081
20
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$23.00
-0.8%
1.70%316,471
21
Viatris Inc. stock logo
VTRS
Viatris
$16.23
+1.2%
1.66%469,989
22
Veradermics, Incorporated stock logo
MANE
Veradermics
$113.18
+2.0%
1.66%79,713
23
Jazz Pharmaceuticals PLC stock logo
JAZZ
Jazz Pharmaceuticals
$244.96
-0.4%
1.66%32,275
24
Maze Therapeutics, Inc. stock logo
MAZE
Maze Therapeutics
$27.18
-1.8%
1.66%301,363
25
Merck & Co., Inc. stock logo
MRK
Merck & Co., Inc.
$135.78
+0.2%
1.61%62,239

XPH Geographic Exposure

XPH's largest geographic exposure is United States at 91.6%, followed by Ireland at 3.3%.

  • United States
    91.6%
  • Ireland
    3.3%
  • Canada
    2.8%
  • Cayman Islands
    0.9%

XPH Currency Exposure

XPH is exclusively exposed to USD.

  • USD
    100.0%

XPH Sector Exposure

XPH's largest sector exposure is Health Care at 83.4%, followed by Energy at 2.3%.

  • Health Care
    83.4%
  • Energy
    2.3%
  • Industrials
    1.0%

XPH Industry Exposure

XPH's largest industry exposure is Biotechnology at 41.6%, followed by Pharmaceuticals at 40.1%.

  • Biotechnology
    41.6%
  • Pharmaceuticals
    40.1%
  • Renewable Energy
    2.3%
  • Health Care Equipment & Supplies
    1.7%
  • Commercial Services & Supplies
    1.0%

XPH Sub-Industry Exposure

XPH's largest sub-industry exposure is Pharmaceuticals at 44.4%, followed by Biotechnology at 32.1%.

  • Pharmaceuticals
    44.4%
  • Biotechnology
    32.1%
  • Renewable Energy Equipment
    2.3%
  • Health Care Supplies
    1.7%

XPH Coupon Exposure

XPH's largest coupon exposure is 2-4 at 0.1%, followed by 0-2 at 0.0%.

  • 2-4
    0.1%

XPH Maturity Exposure

XPH's largest maturity exposure is 20-30 at 0.1%, followed by 3-5 at 0.0%.

  • 20-30
    0.1%

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This page (NYSEARCA:XPH) was last updated on 8/16/2026 by MarketBeat.com Staff.
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