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SPDR S&P Pharmaceuticals ETF (XPH) Holdings List

SPDR S&P Pharmaceuticals ETF logo
$70.79 -1.62 (-2.24%)
As of 08/28/2026 04:10 PM Eastern

What stocks does XPH hold?

The SPDR S&P Pharmaceuticals ETF (XPH) top stock holdings include Crinetics Pharmaceuticals, MBX Biosciences, and Atai Beckley. The top 25 XPH holdings ordered by weight make up 51.49% of the total fund. XPH is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XPH stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XPH Holdings

RankCompanyCurrent PriceWeightShares Held
1
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$84.84
0.0%
3.62%226,466
2
MBX Biosciences, Inc. stock logo
MBX
MBX Biosciences
$63.00
-5.1%
3.19%250,803
3
Atai Beckley N.V. stock logo
ATAI
Atai Beckley
$7.29
-0.8%
2.82%2,056,188
4
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$40.98
-6.5%
2.78%334,441
5
Omeros Corporation stock logo
OMER
Omeros
$18.61
-3.3%
2.50%761,998
6
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$34.74
-6.6%
2.46%577,445
7
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$57.86
-4.4%
2.31%210,063
8
Corcept Therapeutics Incorporated stock logo
CORT
Corcept Therapeutics
$113.88
-2.6%
2.08%99,495
9
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$16.79
-6.5%
1.99%580,030
10
Nektar Therapeutics stock logo
NKTR
Nektar Therapeutics
$72.52
-2.7%
1.97%136,881
11
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$6.70
-4.1%
1.96%1,697,029
12
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$42.76
-3.2%
1.93%236,099
13
Alumis Inc. stock logo
ALMS
Alumis
$22.38
-3.6%
1.79%387,454
14
Veradermics, Incorporated stock logo
MANE
Veradermics
$97.64
-4.1%
1.76%83,591
15
Ligand Pharmaceuticals Incorporated stock logo
LGND
Ligand Pharmaceuticals
$280.49
-1.4%
1.71%31,316
16
Bristol Myers Squibb Company stock logo
BMY
Bristol Myers Squibb
$66.62
-0.5%
1.71%139,794
17
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$10.36
-4.3%
1.70%889,291
18
Perrigo Company plc stock logo
PRGO
Perrigo
$14.54
+1.2%
1.69%695,828
19
Merck & Co., Inc. stock logo
MRK
Merck & Co., Inc.
$148.30
-0.8%
1.68%65,270
20
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$17.54
-2.6%
1.66%507,335
21
Maze Therapeutics, Inc. stock logo
MAZE
Maze Therapeutics
$27.44
-4.1%
1.66%316,028
22
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$71.76
-0.2%
1.66%126,856
23
Liquidia Corporation stock logo
LQDA
Liquidia
$67.69
-3.2%
1.63%119,121
24
Johnson & Johnson stock logo
JNJ
Johnson & Johnson
$268.30
+1.0%
1.62%32,590
25
Eyepoint Pharmaceuticals, Inc. stock logo
EYPT
Eyepoint Pharmaceuticals
$4.48
-3.2%
1.61%630,365

XPH Geographic Exposure

XPH's largest geographic exposure is United States at 91.6%, followed by Ireland at 3.4%.

  • United States
    91.6%
  • Ireland
    3.4%
  • Canada
    2.7%
  • Cayman Islands
    0.9%

XPH Currency Exposure

XPH is exclusively exposed to USD.

  • USD
    100.0%

XPH Sector Exposure

XPH's largest sector exposure is Health Care at 84.0%, followed by Energy at 2.3%.

  • Health Care
    84.0%
  • Energy
    2.3%
  • Industrials
    1.0%

XPH Industry Exposure

XPH's largest industry exposure is Biotechnology at 41.8%, followed by Pharmaceuticals at 40.5%.

  • Biotechnology
    41.8%
  • Pharmaceuticals
    40.5%
  • Renewable Energy
    2.3%
  • Health Care Equipment & Supplies
    1.8%
  • Commercial Services & Supplies
    1.0%

XPH Sub-Industry Exposure

XPH's largest sub-industry exposure is Pharmaceuticals at 45.4%, followed by Biotechnology at 31.9%.

  • Pharmaceuticals
    45.4%
  • Biotechnology
    31.9%
  • Renewable Energy Equipment
    2.3%
  • Health Care Supplies
    1.8%

XPH Coupon Exposure

XPH's largest coupon exposure is 2-4 at 0.1%.

  • 2-4
    0.1%

XPH Maturity Exposure

XPH's largest maturity exposure is 20-30 at 0.1%, followed by 3-5 at 0.0%.

  • 20-30
    0.1%

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MarketBeat tracks SPDR S&P Pharmaceuticals ETF holdings and portfolio composition, last updated on 8/18/2026.
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