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SPDR S&P Pharmaceuticals ETF (XPH) Holdings List

SPDR S&P Pharmaceuticals ETF logo
$67.51 -0.50 (-0.74%)
Closing price 09/11/2026 04:10 PM Eastern
Extended Trading
$67.67 +0.16 (+0.24%)
As of 09/11/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

What stocks does XPH hold?

The SPDR S&P Pharmaceuticals ETF (XPH) top stock holdings include Amylyx Pharmaceuticals, Crinetics Pharmaceuticals, and MBX Biosciences. The top 25 XPH holdings ordered by weight make up 52.99% of the total fund. XPH is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XPH stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XPH Holdings

RankCompanyCurrent PriceWeightShares Held
1
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$31.62
-1.5%
3.98%592,761
2
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$84.95
3.43%232,474
3
MBX Biosciences, Inc. stock logo
MBX
MBX Biosciences
$59.02
-3.2%
3.07%257,455
4
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$38.89
+3.1%
2.74%343,312
5
Atai Beckley N.V. stock logo
ATAI
Atai Beckley
$7.35
2.71%2,110,723
6
Omeros Corporation stock logo
OMER
Omeros
$18.28
-1.7%
2.50%782,209
7
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$54.32
-3.4%
2.23%215,635
8
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$6.11
-2.8%
2.20%1,742,037
9
Corcept Therapeutics Incorporated stock logo
CORT
Corcept Therapeutics
$112.79
-1.9%
2.12%102,135
10
Eton Pharmaceuticals, Inc. stock logo
ETON
Eton Pharmaceuticals
$57.08
-1.4%
2.02%188,463
11
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$44.40
+3.5%
1.96%242,359
12
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$15.90
-0.1%
1.95%595,414
13
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$10.49
-1.2%
1.86%912,878
14
Nektar Therapeutics stock logo
NKTR
Nektar Therapeutics
$69.76
-1.3%
1.86%140,513
15
Merck & Co., Inc. stock logo
MRK
Merck & Co., Inc.
$144.02
-0.5%
1.78%67,002
16
Perrigo Company plc stock logo
PRGO
Perrigo
$13.66
+0.5%
1.74%714,284
17
Bristol Myers Squibb Company stock logo
BMY
Bristol Myers Squibb
$63.53
-0.4%
1.69%143,502
18
Maze Therapeutics, Inc. stock logo
MAZE
Maze Therapeutics
$24.60
-0.9%
1.68%324,408
19
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$79.31
-2.2%
1.67%130,220
20
Veradermics, Incorporated stock logo
MANE
Veradermics
$99.20
+1.1%
1.66%85,807
21
Alumis Inc. stock logo
ALMS
Alumis
$9.18
-7.3%
1.66%397,730
22
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$17.01
+0.8%
1.64%520,791
23
Ligand Pharmaceuticals Incorporated stock logo
LGND
Ligand Pharmaceuticals
$284.47
-1.7%
1.63%32,148
24
Harrow, Inc. stock logo
HROW
Harrow
$34.48
-5.7%
1.61%222,243
25
Liquidia Corporation stock logo
LQDA
Liquidia
$66.74
-1.6%
1.60%122,281

XPH Geographic Exposure

XPH's largest geographic exposure is United States at 91.2%, followed by Ireland at 3.7%.

  • United States
    91.2%
  • Ireland
    3.7%
  • Canada
    2.6%
  • Cayman Islands
    1.0%

XPH Currency Exposure

XPH is exclusively exposed to USD.

  • USD
    100.0%

XPH Sector Exposure

XPH's largest sector exposure is Health Care at 86.0%, followed by Energy at 2.4%.

  • Health Care
    86.0%
  • Energy
    2.4%
  • Industrials
    1.1%

XPH Industry Exposure

XPH's largest industry exposure is Biotechnology at 42.1%, followed by Pharmaceuticals at 42.0%.

  • Biotechnology
    42.1%
  • Pharmaceuticals
    42.0%
  • Renewable Energy
    2.4%
  • Health Care Equipment & Supplies
    2.0%
  • Commercial Services & Supplies
    1.1%

XPH Sub-Industry Exposure

XPH's largest sub-industry exposure is Pharmaceuticals at 47.3%, followed by Biotechnology at 31.3%.

  • Pharmaceuticals
    47.3%
  • Biotechnology
    31.3%
  • Renewable Energy Equipment
    2.4%
  • Health Care Supplies
    2.0%

XPH Coupon Exposure

XPH's largest coupon exposure is 2-4 at 0.1%, followed by 0-2 at 0.0%.

  • 2-4
    0.1%

XPH Maturity Exposure

XPH's largest maturity exposure is 3-5 at 0.1%.

  • 3-5
    0.1%

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MarketBeat tracks SPDR S&P Pharmaceuticals ETF holdings and portfolio composition, last updated on 9/11/2026.
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