Frazier Life Sciences Management, L.P. Top Holdings and 13F Report (2025) About Frazier Life Sciences Management, L.P.Investment ActivityFrazier Life Sciences Management, L.P. has $2.19 billion in total holdings as of March 31, 2025.Frazier Life Sciences Management, L.P. owns shares of 47 different stocks, but just 15 companies or ETFs make up 80% of its holdings.Approximately 6.13% of the portfolio was purchased this quarter.About 10.27% of the portfolio was sold this quarter.This quarter, Frazier Life Sciences Management, L.P. has purchased 50 new stocks and bought additional shares in 10 stocks.Frazier Life Sciences Management, L.P. sold shares of 8 stocks and completely divested from 7 stocks this quarter.Largest Holdings NewAmsterdam Pharma $329,903,076Mirum Pharmaceuticals $306,120,201Verona Pharma $219,538,897Arcutis Biotherapeutics $137,401,842BridgeBio Pharma $131,381,798 Largest New Holdings this Quarter 578784100 - MAZE THERAPEUTICS INC $45,460,301 Holding05370A108 - Avidity Biosciences $15,498,000 Holding26818M108 - DYNE THERAPEUTICS INC $15,097,347 Holding98887Q104 - Zai Lab $12,649,000 Holding Largest Purchases this Quarter MAZE THERAPEUTICS INC 4,129,001 shares (about $45.46M)Avidity Biosciences 525,000 shares (about $15.50M)DYNE THERAPEUTICS INC 1,443,341 shares (about $15.10M)Zai Lab 350,000 shares (about $12.65M)Mirum Pharmaceuticals 224,729 shares (about $10.12M) Largest Sales this Quarter Rhythm Pharmaceuticals 1,191,048 shares (about $63.09M)Krystal Biotech 100,000 shares (about $18.03M)Soleno Therapeutics 200,000 shares (about $14.29M)ORIC Pharmaceuticals 2,478,045 shares (about $13.83M)Tarsus Pharmaceuticals 190,000 shares (about $9.76M) Sector Allocation Over TimeMap of 500 Largest Holdings ofFrazier Life Sciences Management, L.P. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNAMSNewAmsterdam Pharma$329,903,076$4,094,000 ▲1.3%16,116,41815.1%MedicalMIRMMirum Pharmaceuticals$306,120,201$10,124,041 ▲3.4%6,795,12114.0%MedicalVRNAVerona Pharma$219,538,897$4,691,911 ▲2.2%3,457,85010.0%MedicalARQTArcutis Biotherapeutics$137,401,8420.0%8,785,2846.3%MedicalBBIOBridgeBio Pharma$131,381,7980.0%3,800,4576.0%MedicalKRYSKrystal Biotech$124,129,338$18,030,000 ▼-12.7%688,4605.7%MedicalIRONDisc Medicine$87,109,9600.0%1,754,8344.0%MedicalTARSTarsus Pharmaceuticals$71,790,962$9,760,300 ▼-12.0%1,397,5273.3%MedicalTRVITrevi Therapeutics$64,531,683$2,549,746 ▼-3.8%10,259,4092.9%MedicalPHATPhathom Pharmaceuticals$63,385,1790.0%10,109,2792.9%MedicalKALVKalVista Pharmaceuticals$56,405,9850.0%4,887,8672.6%MedicalMAZE THERAPEUTICS INC$45,460,301$45,460,301 ▲New Holding4,129,0012.1%COMMBX BIOSCIENCES INC$44,171,8610.0%5,985,3472.0%COMRYTMRhythm Pharmaceuticals$35,953,917$63,089,812 ▼-63.7%678,7601.6%MedicalSLNOSoleno Therapeutics$35,664,911$14,290,000 ▼-28.6%499,1591.6%MedicalRVMDRevolution Medicines$35,270,0090.0%997,4551.6%MedicalSVRASavara$31,750,574$7,761,324 ▲32.4%11,462,3011.5%MedicalAGIOAgios Pharmaceuticals$31,346,722$2,930 ▲0.0%1,069,8541.4%MedicalERASErasca$30,928,916$4,362,305 ▲16.4%22,575,8511.4%MedicalRAREUltragenyx Pharmaceutical$23,852,0700.0%658,7151.1%MedicalASNDAscendis Pharma A/S$20,781,2810.0%133,3330.9%MedicalPCVXVaxcyte$20,367,9330.0%539,4050.9%MedicalALKSAlkermes$19,849,2800.0%601,1290.9%MedicalPALVELLA THERAPEUTICS INC NE$19,313,436$1,010,999 ▲5.5%690,0120.9%COMCG ONCOLOGY INC$18,857,3000.0%770,0000.9%COMMREOMereo BioPharma Group$17,594,692$6,124,689 ▲53.4%7,819,8630.8%MedicalMRUSMerus$15,703,7790.0%373,1000.7%MedicalRNAAvidity Biosciences$15,498,000$15,498,000 ▲New Holding525,0000.7%MedicalHLVXHilleVax$15,394,7400.0%10,617,0620.7%MedicalDYNE THERAPEUTICS INC$15,097,347$15,097,347 ▲New Holding1,443,3410.7%COMZLABZai Lab$12,649,000$12,649,000 ▲New Holding350,0000.6%MedicalIMCRImmunocore$8,935,714$5,708,745 ▲176.9%301,1700.4%MedicalORICORIC Pharmaceuticals$7,868,877$13,827,491 ▼-63.7%1,410,1930.4%MedicalACADACADIA Pharmaceuticals$7,812,3140.0%470,3380.4%MedicalDSGNDesign Therapeutics$7,540,6910.0%1,953,5470.3%MedicalRCKTRocket Pharmaceuticals$7,197,097$2,668,000 ▼-27.0%1,079,0250.3%MedicalAUTLAutolus Therapeutics$7,166,1520.0%4,623,3240.3%MedicalORUKA THERAPEUTICS INC$5,984,9350.0%583,3270.3%COMALLOAllogene Therapeutics$5,648,375$1,461,460 ▲34.9%3,868,7500.3%MedicalIMTXImmatics$5,628,079$4,059,000 ▼-41.9%1,247,9110.3%MedicalCOGTCogent Biosciences$5,610,0900.0%936,5760.3%MedicalADVERUM BIOTECHNOLOGIES INC$4,672,5960.0%1,069,2440.2%COM NEWNAMSWNewAmsterdam Pharma$4,497,9940.0%500,3330.2%MedicalMGNXMacroGenics$4,033,0950.0%3,175,6650.2%MedicalLEXEO THERAPEUTICS INC$3,315,6370.0%955,5150.2%COMSLNSilence Therapeutics$3,239,0270.0%1,148,5910.1%MedicalELEVElevation Oncology$1,552,9360.0%5,993,5790.1%MedicalEWTXEdgewise Therapeutics$0$33,942,242 ▼-100.0%00.0%MedicalANABAnaptysBio$0$20,836,040 ▼-100.0%00.0%MedicalPLRXPliant Therapeutics$0$14,760,976 ▼-100.0%00.0%MedicalDAWNDay One Biopharmaceuticals$0$8,737,929 ▼-100.0%00.0%MedicalETNB89bio$0$7,820,000 ▼-100.0%00.0%MedicalARVNArvinas$0$5,469,795 ▼-100.0%00.0%MedicalELDNEledon Pharmaceuticals$0$4,848,148 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
