Frazier Life Sciences Management, L.P. Top Holdings and 13F Report (2025) About Frazier Life Sciences Management, L.P.Investment ActivityFrazier Life Sciences Management, L.P. has $2.50 billion in total holdings as of June 30, 2025.Frazier Life Sciences Management, L.P. owns shares of 49 different stocks, but just 17 companies or ETFs make up 80% of its holdings.Approximately 11.49% of the portfolio was purchased this quarter.About 5.07% of the portfolio was sold this quarter.This quarter, Frazier Life Sciences Management, L.P. has purchased 47 new stocks and bought additional shares in 16 stocks.Frazier Life Sciences Management, L.P. sold shares of 5 stocks and completely divested from 6 stocks this quarter.Largest Holdings Mirum Pharmaceuticals $345,803,708Verona Pharma PLC American Depositary Share $320,053,991NewAmsterdam Pharma $300,754,110BridgeBio Pharma $164,103,733Arcutis Biotherapeutics $138,440,644 Largest New Holdings this Quarter 05153U107 - Aura Biosciences $31,926,000 Holding30052C107 - Evolus $22,431,416 Holding00973Y108 - Akero Therapeutics $19,571,594 Holding23282W605 - Cytokinetics $18,328,312 Holding008064206 - JADE BIOSCIENCES INC $17,703,439 Holding Largest Purchases this Quarter Zai Lab 958,138 shares (about $33.51M)Aura Biosciences 5,100,000 shares (about $31.93M)Phathom Pharmaceuticals 2,357,210 shares (about $22.61M)Evolus 2,435,550 shares (about $22.43M)Akero Therapeutics 366,784 shares (about $19.57M) Largest Sales this Quarter Verona Pharma PLC American Depositary Share 73,900 shares (about $6.99M)Disc Medicine 100,000 shares (about $5.30M)Oric Pharmaceuticals 344,859 shares (about $3.50M)Vaxcyte 65,000 shares (about $2.11M)Silence Therapeutics 178,461 shares (about $1.04M) Sector Allocation Over TimeMap of 500 Largest Holdings ofFrazier Life Sciences Management, L.P. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorMIRMMirum Pharmaceuticals$345,803,7080.0%6,795,12113.8%MedicalVRNAVerona Pharma PLC American Depositary Share$320,053,991$6,989,462 ▼-2.1%3,383,95012.8%MedicalNAMSNewAmsterdam Pharma$300,754,110$8,885,780 ▲3.0%16,607,07412.0%MedicalBBIOBridgeBio Pharma$164,103,7330.0%3,800,4576.6%MedicalARQTArcutis Biotherapeutics$138,440,644$15,270,963 ▲12.4%9,874,5115.5%MedicalPHATPhathom Pharmaceuticals$119,553,630$22,605,644 ▲23.3%12,466,4894.8%MedicalKRYSKrystal Biotech$94,635,7120.0%688,4603.8%MedicalIRONDisc Medicine$87,640,009$5,296,000 ▼-5.7%1,654,8343.5%MedicalMBX BIOSCIENCES INC$68,292,8090.0%5,985,3472.7%COMTARSTarsus Pharmaceuticals$56,613,8190.0%1,397,5272.3%MedicalTRVITrevi Therapeutics$56,118,9670.0%10,259,4092.2%MedicalMAZE THERAPEUTICS INC$56,040,464$5,377,622 ▲10.6%4,567,2752.2%COMKALVKalVista Pharmaceuticals$55,257,3360.0%4,887,8672.2%MedicalZLABZai Lab$45,745,586$33,506,086 ▲273.8%1,308,1381.8%MedicalAGIOAgios Pharmaceuticals$42,564,618$6,981,274 ▲19.6%1,279,7541.7%MedicalRVMDRevolution Medicines$36,696,3690.0%997,4551.5%MedicalRAREUltragenyx Pharmaceutical$35,767,877$11,817,000 ▲49.3%983,7151.4%MedicalAURAAura Biosciences$31,926,000$31,926,000 ▲New Holding5,100,0001.3%MedicalERASErasca$28,866,384$195,053 ▲0.7%22,729,4361.2%MedicalALKSAlkermes$28,628,511$11,430,210 ▲66.5%1,000,6471.1%MedicalSVRASavara$26,134,0460.0%11,462,3011.0%MedicalMREOMereo BioPharma Group$25,582,704$4,390,875 ▲20.7%9,440,1121.0%MedicalASNDAscendis Pharma A/S$23,013,2760.0%133,3330.9%MedicalEOLSEvolus$22,431,416$22,431,416 ▲New Holding2,435,5500.9%MedicalHLVXHilleVax$21,127,9530.0%10,617,0620.8%MedicalCG ONCOLOGY INC$20,020,0000.0%770,0000.8%COMAKROAkero Therapeutics$19,571,594$19,571,594 ▲New Holding366,7840.8%MedicalCYTKCytokinetics$18,328,312$18,328,312 ▲New Holding554,7310.7%MedicalLEXEO THERAPEUTICS INC$17,787,395$13,946,225 ▲363.1%4,424,7250.7%COMRNAAvidity Biosciences$17,750,000$2,840,000 ▲19.0%625,0000.7%MedicalJADE BIOSCIENCES INC$17,703,439$17,703,439 ▲New Holding1,772,1160.7%COM NEWPALVELLA THERAPEUTICS INC NE$16,282,896$730,026 ▲4.7%722,4000.7%COMPCVXVaxcyte$15,422,907$2,113,150 ▼-12.1%474,4050.6%MedicalTVTXTravere Therapeutics$14,830,962$14,830,962 ▲New Holding1,002,0920.6%MedicalDYNE THERAPEUTICS INC$14,336,968$596,361 ▲4.3%1,505,9840.6%COMCOGTCogent Biosciences$12,454,435$5,729,819 ▲85.2%1,734,6010.5%MedicalIMCRImmunocore$12,074,459$2,623,745 ▲27.8%384,7820.5%MedicalORICOric Pharmaceuticals$10,813,140$3,500,319 ▼-24.5%1,065,3340.4%MedicalAUTLAutolus Therapeutics$10,541,1790.0%4,623,3240.4%MedicalVALNValneva$8,239,581$8,239,581 ▲New Holding1,458,3330.3%MedicalCRESCENT BIOPHARMA INC.$7,322,476$7,322,476 ▲New Holding453,6850.3%COMDSGNDesign Therapeutics$6,583,4530.0%1,953,5470.3%MedicalORUKA THERAPEUTICS INC$6,539,0960.0%583,3270.3%COMSLNSilence Therapeutics$5,626,754$1,035,074 ▼-15.5%970,1300.2%MedicalALLOAllogene Therapeutics$4,371,6880.0%3,868,7500.2%MedicalNAMSWNewAmsterdam Pharma$4,002,6640.0%500,3330.2%MedicalMGNXMacroGenics$3,842,5550.0%3,175,6650.2%MedicalADVERUM BIOTECHNOLOGIES INC$2,298,8750.0%1,069,2440.1%COM NEWELEVElevation Oncology$2,200,2430.0%5,993,5790.1%MedicalRYTMRhythm Pharmaceuticals$0$35,953,917 ▼-100.0%00.0%MedicalSLNOSoleno Therapeutics$0$35,664,911 ▼-100.0%00.0%MedicalMRUSMerus$0$15,703,779 ▼-100.0%00.0%MedicalACADACADIA Pharmaceuticals$0$7,812,314 ▼-100.0%00.0%MedicalRCKTRocket Pharmaceuticals$0$7,197,097 ▼-100.0%00.0%MedicalIMTXImmatics$0$5,628,079 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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