Ra Capital Management, L.P. Top Holdings and 13F Report (2025) About Ra Capital Management, L.P.Investment ActivityRa Capital Management, L.P. has $5.94 billion in total holdings as of June 30, 2025.Ra Capital Management, L.P. owns shares of 63 different stocks, but just 17 companies or ETFs make up 80% of its holdings.Approximately 4.49% of the portfolio was purchased this quarter.About 9.35% of the portfolio was sold this quarter.This quarter, Ra Capital Management, L.P. has purchased 85 new stocks and bought additional shares in 9 stocks.Ra Capital Management, L.P. sold shares of 9 stocks and completely divested from 28 stocks this quarter.Largest Holdings Ascendis Pharma A/S $1,774,586,210Vaxcyte $389,014,367Rhythm Pharmaceuticals $351,422,275Janux Therapeutics $258,481,908Avidity Biosciences $206,355,280 Largest New Holdings this Quarter 433313103 - HINGE HEALTH INC-A $15,525,000 Holding008064206 - JADE BIOSCIENCES INC $10,612,637 Holding87583X109 - Tango Therapeutics $10,240,000 Holding68170A108 - OMADA HEALTH INC $7,320,000 Holding81663L200 - GeneDx $5,358,042 Holding Largest Purchases this Quarter CIDARA THERAPEUTICS INC 2,272,727 shares (about $110.70M)Taysha Gene Therapies 12,683,145 shares (about $29.30M)Avidity Biosciences 965,623 shares (about $27.42M)HINGE HEALTH INC-A 300,000 shares (about $15.53M)Tyra Biosciences 1,561,335 shares (about $14.94M) Largest Sales this Quarter Rhythm Pharmaceuticals 523,053 shares (about $33.05M)10x Genomics 1,468,904 shares (about $17.01M)MBX BIOSCIENCES INC 1,133,493 shares (about $12.93M)Vaxcyte 223,158 shares (about $7.25M)Protara Therapeutics 2,360,705 shares (about $7.15M) Sector Allocation Over TimeMap of 500 Largest Holdings ofRa Capital Management, L.P. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorASNDAscendis Pharma A/S$1,774,586,2100.0%10,281,49629.9%MedicalPCVXVaxcyte$389,014,367$7,254,867 ▼-1.8%11,965,9916.6%MedicalRYTMRhythm Pharmaceuticals$351,422,275$33,051,719 ▼-8.6%5,561,3595.9%MedicalJANXJanux Therapeutics$258,481,9080.0%11,189,6934.4%MedicalRNAAvidity Biosciences$206,355,280$27,423,693 ▲15.3%7,266,0313.5%MedicalACLXArcellx$199,955,3030.0%3,036,5273.4%MedicalETNB89BIO$195,316,6870.0%19,889,6833.3%MedicalSPRYARS Pharmaceuticals$189,524,0490.0%10,860,9773.2%MedicalNAMSNewAmsterdam Pharma$183,616,1670.0%10,138,9383.1%MedicalSIONNA THERAPEUTICS INC$181,226,3370.0%10,445,3223.1%SHCIDARA THERAPEUTICS INC$163,934,625$110,704,532 ▲208.0%3,365,5232.8%SHEWTXEdgewise Therapeutics$129,823,519$13,025,336 ▲11.2%9,902,6332.2%MedicalLENZ THERAPEUTICS INC$122,481,3020.0%4,178,8232.1%SHWVEWAVE Life Sciences$118,313,0590.0%18,202,0092.0%MedicalTYRATyra Biosciences$116,740,841$14,941,976 ▲14.7%12,198,6252.0%MedicalGHRSGH Research$93,578,936$8,923,677 ▲10.5%7,676,6971.6%MedicalDYNE THERAPEUTICS INC$92,481,0120.0%9,714,3921.6%SHGERNGeron$85,134,9060.0%60,379,3661.4%MedicalIRONDisc Medicine$83,523,5340.0%1,577,1061.4%MedicalMLYSMineralys Therapeutics$83,172,6980.0%6,147,2801.4%MedicalSEPTERNA INC$73,946,2190.0%6,995,8581.2%SHFULCFulcrum Therapeutics$70,376,2010.0%10,229,0991.2%MedicalBICARA THERAPEUTICS INC$64,621,1750.0%6,955,9931.1%SHVORVor Biopharma$64,226,5830.0%39,646,0391.1%MedicalTSHATaysha Gene Therapies$54,413,547$29,298,065 ▲116.7%23,555,6480.9%MedicalDIANTHUS THERAPEUTICS INC$53,407,2360.0%2,866,7330.9%SHRXSTRxSight$48,138,571$520,663 ▼-1.1%3,702,9670.8%MedicalTOURMALINE BIO INC$40,597,4110.0%2,538,9250.7%SHSRRKScholar Rock$40,253,1650.0%1,136,4530.7%MedicalELYMEliem Therapeutics$38,959,8910.0%31,419,2670.7%MedicalGPCRStructure Therapeutics$31,471,2490.0%1,517,4180.5%MedicalSLDBSolid Biosciences$28,301,143$7,211,871 ▲34.2%5,811,3230.5%MedicalMETSERA INC$19,218,6860.0%675,5250.3%SHMONOPAR THERAPEUTICS INC$18,290,9860.0%511,2070.3%SHNKTXNkarta$17,936,5140.0%10,805,1290.3%MedicalLRMRLarimar Therapeutics$17,471,0640.0%6,045,3510.3%MedicalABOSAcumen Pharmaceuticals$17,321,1930.0%14,932,0630.3%MedicalELVNEnliven Therapeutics$17,030,6590.0%848,9860.3%MedicalTVTXTravere Therapeutics$17,020,0000.0%1,150,0000.3%MedicalFDMT4D Molecular Therapeutics$16,929,5130.0%4,563,2110.3%MedicalHINGE HEALTH INC-A$15,525,000$15,525,000 ▲New Holding300,0000.3%SHARTIVA BIOTHERAPEUTICS INC$14,878,4860.0%9,853,3020.3%SHPEPGPepGen$11,865,3950.0%10,689,5450.2%MedicalJADE BIOSCIENCES INC$10,612,637$10,612,637 ▲New Holding1,062,3260.2%SHTNGXTango Therapeutics$10,240,000$10,240,000 ▲New Holding2,000,0000.2%MedicalACRVAcrivon Therapeutics$9,925,2050.0%8,340,5080.2%MedicalELDNEledon Pharmaceuticals$9,664,7760.0%3,566,3380.2%MedicalRCUSArcus Biosciences$9,250,0030.0%1,136,3640.2%MedicalPERCEPTIVE CAPITAL SOLUTIONS$7,965,0000.0%750,0000.1%SHOMADA HEALTH INC$7,320,000$7,320,000 ▲New Holding400,0000.1%SHHOWLWerewolf Therapeutics$7,282,625$584,704 ▲8.7%6,681,3070.1%MedicalBETA BIONICS INC$7,280,0000.0%500,0000.1%SHCTMXCytomX Therapeutics$6,041,221$3,771,221 ▲166.1%2,661,3310.1%MedicalTXG10x Genomics$5,504,472$17,009,909 ▼-75.6%475,3430.1%MedicalSURROZEN INC$5,387,476$683,946 ▼-11.3%602,6260.1%SHWGSGeneDx$5,358,042$5,358,042 ▲New Holding58,0440.1%MedicalAVALO THERAPEUTICS INC$4,655,535$169,795 ▼-3.5%932,9730.1%SHACETAdicet Bio$4,600,0100.0%7,541,0000.1%MedicalMBX BIOSCIENCES INC$4,311,166$12,933,156 ▼-75.0%377,8410.1%SHTARAProtara Therapeutics$3,149,064$7,152,936 ▼-69.4%1,039,2950.1%MedicalNAMSWNewAmsterdam Pharma$2,666,6640.0%333,3330.0%MedicalACHCAcadia Healthcare$2,025,355$2,898,376 ▼-58.9%89,2620.0%MedicalIFRXInflaRx$1,558,854$1,558,854 ▲New Holding1,973,2330.0%MedicalAPOGEE THERAPEUTICS INC$0$58,636,184 ▼-100.0%00.0%SHZLABZai Lab$0$46,802,746 ▼-100.0%00.0%MedicalDAWNDay One Biopharmaceuticals$0$45,641,726 ▼-100.0%00.0%MedicalURGNUrogen Pharma$0$35,461,357 ▼-100.0%00.0%MedicalATXSAstria Therapeutics$0$27,261,837 ▼-100.0%00.0%MedicalKURAKura Oncology$0$26,430,426 ▼-100.0%00.0%MedicalAVTEAerovate Therapeutics$0$23,072,151 ▼-100.0%00.0%MedicalIDYAIDEAYA Biosciences$0$22,067,988 ▼-100.0%00.0%MedicalITOSiTeos Therapeutics$0$21,784,870 ▼-100.0%00.0%MedicalGKOSGlaukos$0$18,724,996 ▼-100.0%00.0%MedicalEYPTEyepoint Pharmaceuticals$0$17,245,454 ▼-100.0%00.0%MedicalCERIBELL INC$0$15,840,220 ▼-100.0%00.0%SHNRIXNurix Therapeutics$0$15,839,996 ▼-100.0%00.0%MedicalINSMInsmed$0$15,258,000 ▼-100.0%00.0%MedicalALECAlector$0$11,925,130 ▼-100.0%00.0%MedicalSERASera Prognostics$0$11,160,733 ▼-100.0%00.0%MedicalBCYCBicycle Therapeutics$0$9,283,620 ▼-100.0%00.0%MedicalIMTXImmatics$0$7,892,500 ▼-100.0%00.0%MedicalBright Minds Biosciences Inc$0$7,445,822 ▼-100.0%00.0%SHACRSAclaris Therapeutics$0$7,140,001 ▼-100.0%00.0%MedicalXNCRXencor$0$6,118,000 ▼-100.0%00.0%MedicalHUMAHumacyte$0$5,647,567 ▼-100.0%00.0%MedicalZURAZura Bio$0$4,150,579 ▼-100.0%00.0%MedicalBIOAGE LABS INC$0$3,957,377 ▼-100.0%00.0%SHBOUNDLESS BIO INC$0$3,292,753 ▼-100.0%00.0%SHSTROSutro Biopharma$0$2,885,175 ▼-100.0%00.0%MedicalLEXEO THERAPEUTICS INC$0$1,896,542 ▼-100.0%00.0%SHSCLXScilex$0$257,500 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
MarketBeat All Access