Sofinnova Investments, Inc. Top Holdings and 13F Report (2025) About Sofinnova Investments, Inc.Investment ActivitySofinnova Investments, Inc. has $1.53 billion in total holdings as of March 31, 2025.Sofinnova Investments, Inc. owns shares of 62 different stocks, but just 25 companies or ETFs make up 80% of its holdings.Approximately 43.21% of the portfolio was purchased this quarter.About 23.32% of the portfolio was sold this quarter.This quarter, Sofinnova Investments, Inc. has purchased 60 new stocks and bought additional shares in 22 stocks.Sofinnova Investments, Inc. sold shares of 11 stocks and completely divested from 16 stocks this quarter.Largest Holdings Natera $219,225,095Stryker $111,141,566Invesco QQQ $82,061,000Soleno Therapeutics $72,433,938iShares Russell 2000 ETF $69,821,500 Largest New Holdings this Quarter 46090E103 - Invesco QQQ $82,061,000 Holding464287655 - iShares Russell 2000 ETF $69,821,500 HoldingG5960L103 - Medtronic $50,590,461 Holding69366J200 - PTC Therapeutics $29,523,115 Holding10806X102 - BridgeBio Pharma $25,382,227 Holding Largest Purchases this Quarter Invesco QQQ 175,000 shares (about $82.06M)iShares Russell 2000 ETF 350,000 shares (about $69.82M)Stryker 182,562 shares (about $67.96M)Medtronic 562,992 shares (about $50.59M)Eli Lilly and Company 38,436 shares (about $31.74M) Largest Sales this Quarter Axsome Therapeutics 416,409 shares (about $48.57M)Gilead Sciences 355,327 shares (about $39.81M)Intuitive Surgical 25,912 shares (about $12.83M)Incyte 166,467 shares (about $10.08M)Replimune Group 669,583 shares (about $6.53M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSofinnova Investments, Inc. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNTRANatera$219,225,0950.0%1,550,28014.3%MedicalSYKStryker$111,141,566$67,958,705 ▲157.4%298,5677.3%MedicalQQQInvesco QQQ$82,061,000$82,061,000 ▲New Holding175,0005.4%FinanceSLNOSoleno Therapeutics$72,433,938$18,328,568 ▲33.9%1,013,7714.7%MedicalIWMiShares Russell 2000 ETF$69,821,500$69,821,500 ▲New Holding350,0004.6%FinanceVERAVera Therapeutics$67,111,5680.0%2,793,9874.4%MedicalJAZZJazz Pharmaceuticals$63,322,708$727,147 ▲1.2%510,0504.1%MedicalMDTMedtronic$50,590,461$50,590,461 ▲New Holding562,9923.3%MedicalALNYAlnylam Pharmaceuticals$47,572,394$17,827,801 ▲59.9%176,1813.1%MedicalGILDGilead Sciences$46,937,745$39,814,390 ▼-45.9%418,9003.1%MedicalLLYEli Lilly and Company$43,608,048$31,744,677 ▲267.6%52,8002.8%MedicalIDYAIDEAYA Biosciences$42,951,505$25,439,811 ▲145.3%2,622,1922.8%MedicalArrivent BioPharma Inc$31,372,9440.0%1,696,7522.0%COMPTCTPTC Therapeutics$29,523,115$29,523,115 ▲New Holding579,3391.9%MedicalSNDXSyndax Pharmaceuticals$27,951,115$19,859,882 ▲245.4%2,275,2231.8%MedicalDXCMDexCom$27,041,133$7,222,692 ▲36.4%395,9751.8%MedicalBBIOBridgeBio Pharma$25,382,227$25,382,227 ▲New Holding734,2271.7%MedicalREPLReplimune Group$24,179,405$6,528,434 ▼-21.3%2,479,9391.6%MedicalRYTMRhythm Pharmaceuticals$23,669,062$2,617,301 ▲12.4%446,8391.5%MedicalINSMInsmed$23,211,538$3,659,860 ▲18.7%304,2541.5%MedicalBPMCBlueprint Medicines$23,104,562$23,104,562 ▲New Holding261,0391.5%MedicalBMYBristol-Myers Squibb$22,657,602$22,657,602 ▲New Holding371,4971.5%MedicalINCYIncyte$21,664,790$10,079,577 ▼-31.8%357,8001.4%MedicalANABAnaptysBio$21,565,013$19,093,900 ▲772.7%1,160,0331.4%MedicalSRPTSarepta Therapeutics$20,908,581$6,455,585 ▼-23.6%327,6181.4%MedicalAKROAkero Therapeutics$20,645,610$20,645,610 ▲New Holding510,0201.3%MedicalAXSMAxsome Therapeutics$20,447,222$48,565,782 ▼-70.4%175,3171.3%MedicalRapport Therapeutics Inc$20,015,8080.0%1,995,5941.3%COMSUPNSupernus Pharmaceuticals$17,052,205$17,052,205 ▲New Holding520,6781.1%MedicalSVRASavara$15,184,215$28,717 ▲0.2%5,481,6661.0%MedicalEWTXEdgewise Therapeutics$14,577,596$5,716,590 ▲64.5%662,6181.0%MedicalCOGTCogent Biosciences$13,070,905$8,140,177 ▲165.1%2,182,1210.9%MedicalROIVRoivant Sciences$12,910,256$12,910,256 ▲New Holding1,279,5100.8%MedicalDHRDanaher$12,014,230$9,964,230 ▲486.1%58,6060.8%MedicalPENPenumbra$11,481,516$11,481,516 ▲New Holding42,9360.7%MedicalRNAAvidity Biosciences$11,215,563$10,808,512 ▲2,655.3%379,9310.7%MedicalInhibrx Biosciences Inc$9,763,845$2,388,457 ▲32.4%697,9160.6%COMYMABY-mAbs Therapeutics$9,720,6520.0%2,194,2780.6%MedicalAVTEAerovate Therapeutics$9,434,3020.0%3,758,6860.6%MedicalPHVSPharvaris$9,316,427$513,076 ▲5.8%593,4030.6%MedicalBioAge Labs Inc$8,666,4280.0%2,304,9010.6%COMACADACADIA Pharmaceuticals$8,305,000$8,305,000 ▲New Holding500,0000.5%MedicalRCUSArcus Biosciences$8,146,542$8,146,542 ▲New Holding1,037,7760.5%MedicalDyne Therapeutics Inc$7,498,732$3,709,137 ▼-33.1%716,8960.5%COMIMTXImmatics$7,009,911$5,462,052 ▲352.9%1,554,3040.5%MedicalPraxis Precision Medicines I$5,969,827$5,969,827 ▲New Holding157,6400.4%COMISRGIntuitive Surgical$5,935,316$12,833,437 ▼-68.4%11,9840.4%MedicalQUREuniQure$5,785,173$5,785,173 ▲New Holding545,7710.4%MedicalIMNMImmunome$5,307,722$281,597 ▲5.6%788,6660.3%MedicalKURAKura Oncology$5,225,002$5,225,002 ▲New Holding791,6670.3%MedicalINZYInozyme Pharma$3,895,0800.0%4,280,3080.3%MedicalSRRKScholar Rock$3,733,162$3,733,162 ▲New Holding116,1170.2%MedicalERASErasca$2,571,606$111,251 ▲4.5%1,877,0850.2%MedicalNXTCNextCure$1,283,2920.0%2,671,8560.1%MedicalESTAEstablishment Labs$1,170,083$2,718,836 ▼-69.9%28,6750.1%MedicalBOLTBolt Biotherapeutics$1,101,7750.0%2,754,4370.1%MedicalMetsera Inc$1,001,696$1,001,696 ▲New Holding36,8000.1%COMELVNEnliven Therapeutics$660,205$9,407 ▼-1.4%33,5470.0%MedicalGPCRStructure Therapeutics$605,019$243,379 ▲67.3%34,9520.0%MedicalVIRVir Biotechnology$537,905$201,664 ▼-27.3%83,0100.0%MedicalIKNAIkena Oncology$489,7480.0%382,6160.0%MedicalIRONDisc Medicine$371,555$757,853 ▼-67.1%7,4850.0%MedicalABBVAbbVie$0$63,864,136 ▼-100.0%00.0%MedicalAZNAstraZeneca$0$42,676,059 ▼-100.0%00.0%MedicalBSXBoston Scientific$0$30,955,722 ▼-100.0%00.0%MedicalALKSAlkermes$0$25,719,090 ▼-100.0%00.0%MedicalGMEDGlobus Medical$0$20,239,137 ▼-100.0%00.0%MedicalJANXJanux Therapeutics$0$13,559,647 ▼-100.0%00.0%MedicalNARIInari Medical$0$9,212,279 ▼-100.0%00.0%MedicalACHVAchieve Life Sciences$0$4,598,817 ▼-100.0%00.0%MedicalAVTRAvantor$0$4,214,000 ▼-100.0%00.0%MedicalEWEdwards Lifesciences$0$2,961,200 ▼-100.0%00.0%MedicalEXASExact Sciences$0$2,924,240 ▼-100.0%00.0%MedicalKROSKeros Therapeutics$0$1,509,786 ▼-100.0%00.0%MedicalBDXBecton, Dickinson and Company$0$1,123,233 ▼-100.0%00.0%MedicalICUIICU Medical$0$775,850 ▼-100.0%00.0%MedicalTVTXTravere Therapeutics$0$568,171 ▼-100.0%00.0%MedicalLUNGPulmonx$0$416,404 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
