Stonepine Capital Management, LLC Top Holdings and 13F Report (2021) About Stonepine Capital Management, LLCInvestment ActivityStonepine Capital Management, LLC has $213.62 million in total holdings as of September 30, 2021.Stonepine Capital Management, LLC owns shares of 93 different stocks, but just 31 companies or ETFs make up 80% of its holdings.Approximately 45.08% of the portfolio was purchased this quarter.About 67.85% of the portfolio was sold this quarter.This quarter, Stonepine Capital Management, LLC has purchased 72 new stocks and bought additional shares in 28 stocks.Stonepine Capital Management, LLC sold shares of 28 stocks and completely divested from 12 stocks this quarter.Largest Holdings Evolus $14,185,724ADMA Biologics $14,143,800Verastem $12,795,575Aytu BioPharma $9,623,729TENAX THERAPEUTICS INC $9,603,000 Largest New Holdings this Quarter 05479L302 - AZITRA INC $7,981,143 Holding90400D108 - Ultragenyx Pharmaceutical $6,334,750 Holding29014R301 - ELOXX PHARMACEUTICALS INC $6,206,581 Holding457669307 - Insmed $5,600,000 HoldingG5960L103 - Medtronic $4,375,000 Holding Largest Purchases this Quarter Aytu BioPharma 4,197,949 shares (about $8.10M)AZITRA INC 81,797,553 shares (about $7.98M)Ultragenyx Pharmaceutical 225,000 shares (about $6.33M)ELOXX PHARMACEUTICALS INC 447,160 shares (about $6.21M)CNS PHARMACEUTICALS INC 1,284,921 shares (about $6.14M) Largest Sales this Quarter ADMA Biologics 500,000 shares (about $5.09M)TENAX THERAPEUTICS INC 315,200 shares (about $4.59M)Zevra Therapeutics 221,299 shares (about $3.17M)Abeona Therapeutics 289,303 shares (about $1.79M)Evolus 168,929 shares (about $1.19M) Sector Allocation Over TimeMap of 500 Largest Holdings ofStonepine Capital Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorEOLSEvolus$14,185,724$1,192,133 â–¼-7.8%2,010,1626.6%HealthcareADMAADMA Biologics$14,143,800$5,087,698 â–¼-26.5%1,390,0006.6%HealthcareVSTMVerastem$12,795,575$180,789 â–²1.4%3,349,6276.0%HealthcareAYTUAytu BioPharma$9,623,729$8,095,791 â–²529.9%4,990,2384.5%HealthcareTENAX THERAPEUTICS INC$9,603,000$4,586,160 â–¼-32.3%660,0004.5%COM NEWNEKTAR THERAPEUTICS$8,422,856$2,489,006 â–²41.9%120,6543.9%COM NEWAZITRA INC$7,981,143$7,981,143 â–²New Holding81,797,5533.7%COM NEWCNS PHARMACEUTICALS INC$6,433,502$6,141,922 â–²2,106.4%1,345,9213.0%COMRAREUltragenyx Pharmaceutical$6,334,750$6,334,750 â–²New Holding225,0003.0%HealthcareELOXX PHARMACEUTICALS INC$6,206,581$6,206,581 â–²New Holding447,1602.9%COM NEWCAMP4 THERAPEUTICS CORP$6,072,6480.0%1,389,6222.8%COM 13469V AB 4 CAMTEK LTD NOTE 12/0INSMInsmed$5,600,000$5,600,000 â–²New Holding40,0002.6%HealthcareKAZIA THERAPEUTICS LTD$4,860,1200.0%345,1792.3%SPONSORED ADSSURROZEN INC$4,709,606$2,423,749 â–²106.0%68,0012.2%COM NEWMDTMedtronic$4,375,000$4,375,000 â–²New Holding50,0002.0%HealthcareINDIVIOR PHARMACEUTICALS INC$4,103,000$4,103,000 â–²New Holding100,0001.9%COMCRBPCorbus Pharmaceuticals$3,986,500$389,626 â–²10.8%425,0001.9%HealthcareABTAbbott Laboratories$3,800,000$3,800,000 â–²New Holding40,0001.8%HealthcareSATELLOS BIOSCIENCE INC$3,723,291$2,965,946 â–²391.6%491,6241.7%COMZVRAZevra Therapeutics$3,709,772$3,173,427 â–¼-46.1%258,7011.7%HealthcareABEOAbeona Therapeutics$3,444,015$1,787,892 â–¼-34.2%557,2841.6%HealthcareBSXBoston Scientific$3,250,000$3,250,000 â–²New Holding50,0001.5%HealthcareEDESA BIOTECH INC$3,190,807$2,981,087 â–²1,421.5%456,4391.5%COM NEWCURIS INC$3,150,280$2,330,054 â–²284.1%14,312,1871.5%COMBMRNBioMarin Pharmaceutical$3,125,000$3,125,000 â–²New Holding50,0001.5%HealthcareCABACabaletta Bio$2,852,181$2,696,681 â–²1,734.2%917,1001.3%HealthcareAN2 THERAPEUTICS INC$2,670,190$784,821 â–¼-22.7%551,6921.2%COMINHIBIKASE THERAPEUTICS INC$2,379,231$1,456,680 â–²157.9%2,468,5951.1%COM NEWIN8BIO INC$2,290,633$1,355,222 â–²144.9%1,624,5621.1%COM NEWXILIO THERAPEUTICS INC$2,165,023$1,550,351 â–²252.2%225,9941.0%COMADICET BIO INC$2,121,276$203,584 â–²10.6%245,5181.0%COM NEWXERSXeris Biopharma$2,100,000$300,225 â–¼-12.5%280,0001.0%HealthcareQUOIN PHARMACEUTICALS LTD$2,041,567$1,898,999 â–²1,332.0%765,5461.0%SPONSORED ADSTELATELA Bio$1,996,820$33,881 â–²1.7%2,662,4270.9%HealthcareHRTXHeron Therapeutics$1,709,468$1,045,096 â–¼-37.9%1,490,7870.8%HealthcareADIAL PHARMACEUTICALS INC$1,583,177$1,583,177 â–²New Holding727,5630.7%COM NEWSPRUCE BIOSCIENCES INC$1,554,930$1,554,930 â–²New Holding28,7950.7%COM NEWSIBNSiBone$1,500,000$224,460 â–¼-13.0%100,0000.7%HealthcareOKYOOKYO Pharma$1,294,494$19,494 â–²1.5%862,9960.6%HealthcareCALCCalciMedica$1,262,930$1,262,930 â–²New Holding2,128,5970.6%HealthcareNEUMORA THERAPEUTICS INC.$1,250,000$250,000 â–¼-16.7%500,0000.6%COMPASITHEA THERAPEUTICS CORP$1,134,637$706,184 â–²164.8%2,201,4680.5%COM NEWSOL-GEL TECHNOLOGIES LTD$1,072,732$986,730 â–¼-47.9%14,4690.5%SHS NEWLUNGPulmonx$1,060,067$61,292 â–²6.1%815,4360.5%HealthcareX4 PHARMACEUTICALS INC$1,050,699$515,195 â–¼-32.9%224,9890.5%COM NEWARDXArdelyx$1,050,0000.0%150,0000.5%HealthcareDCTHDelcath Systems$1,000,0000.0%100,0000.5%HealthcareMLTXMoonLake Immunotherapeutics$973,500$973,500 â–²New Holding50,0000.5%HealthcareCYBIN INC$965,796$574,078 â–²146.6%330,5300.5%COM NEWMXCTMaxCyte$924,475$311,272 â–¼-25.2%751,6060.4%HealthcarePHATPhathom Pharmaceuticals$922,358$379,750 â–²70.0%85,0100.4%HealthcareCONNECT BIOPHARMA HLDGS LTD$866,925$129,125 â–²17.5%364,2540.4%SHSRADIOPHARM THERANOSTICS LTD$794,013$397,007 â–²100.0%102,000,0000.4%SPONSORED ADSZNTLZentalis Pharmaceuticals$783,678$521,458 â–¼-40.0%161,5830.4%HealthcareCTMXCytomX Therapeutics$768,750$731,250 â–¼-48.8%205,0000.4%HealthcareMNKDMannKind$750,000$798,900 â–¼-51.6%250,0000.4%HealthcareNGENFNervGen Pharma$740,220$740,220 â–²New Holding571,6780.3%HealthcareNVCTNuvectis Pharma$735,600$735,600 â–²New Holding40,0000.3%HealthcareCRESCENT BIOPHARMA INC.$720,000$810,000 â–¼-52.9%40,0000.3%COMPMVPPMV Pharmaceuticals$718,355$230,501 â–¼-24.3%536,0860.3%HealthcareORUKA THERAPEUTICS INC$713,775$713,775 â–²New Holding7,5000.3%COMONKURE THERAPEUTICS INC$595,919$8,637 â–¼-1.4%130,6840.3%COM CL ASINTX TECHNOLOGIES INC$558,432$558,432 â–²New Holding627,6150.3%COM NEWIMAGENEBIO INC$539,044$539,044 â–²New Holding96,1720.3%COMARVNArvinas$498,600$270,075 â–²118.2%60,0000.2%HealthcareBIOAGE LABS INC$490,200$735,300 â–¼-60.0%20,0000.2%COMOPUS GENETICS INC$413,951$131,643 â–²46.6%100,7180.2%COMQT IMAGING HLDGS INC$407,000$407,000 â–²New Holding100,0000.2%COMBOUNDLESS BIO INC$386,488$1,107,719 â–¼-74.1%154,5950.2%COMMLSSMilestone Scientific$348,565$348,565 â–²New Holding666,6660.2%HealthcareCELLECTAR BIOSCIENCES INC$290,649$290,649 â–²New Holding104,5500.1%COM NEWEUPRAXIA PHARMACEUTICALS INC$287,476$287,476 â–²New Holding43,4910.1%COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1SAB BIOTHERAPEUTICS INC$285,757$90,757 â–²46.5%73,2710.1%COM NEWADLAI NORTYE LTD$278,956$278,956 â–²New Holding24,2570.1%SPONSORED ADSSENSEONICS HLDGS INC$276,502$276,502 â–²New Holding48,6800.1%COMPLRXPliant Therapeutics$262,813$6,712 â–²2.6%230,5380.1%HealthcareCDXSCodexis$247,836$696,830 â–¼-73.8%109,6620.1%HealthcareVERRICA PHARMACEUTICALS INC$241,454$30,908 â–¼-11.3%88,4170.1%COM SHSPOCIPrecision Optics$236,589$273,411 â–¼-53.6%46,3900.1%HealthcareUPSTREAM BIO INC$231,349$10,851 â–¼-4.5%33,4320.1%COMREIN THERAPEUTICS INC$226,760$226,760 â–²New Holding218,0380.1%COM NEWINOVIO PHARMACEUTICALS INC$210,176$210,176 â–²New Holding1,345,2370.1%COM SHSHUMAHumacyte$180,506$180,506 â–²New Holding231,2990.1%HealthcarePRECISION BIOSCIENCES INC$128,418$128,418 â–²New Holding40,0000.1%COM NEWKALARIS THERAPEUTICS INC$122,597$39,569 â–²47.7%30,1220.1%COMTNYATenaya Therapeutics$107,429$107,429 â–²New Holding352,0010.1%HealthcarePROCESSA PHARMACEUTICALS INC$105,6000.0%55,0000.0%COM SHSBIOATLA INC$68,028$68,028 â–²New Holding16,4320.0%COM NEWCGENCompugen$67,168$156,033 â–¼-69.9%31,3870.0%HealthcareGRACE THERAPEUTICS INC$62,125$62,125 â–²New Holding294,5500.0%COMOVIDOvid Therapeutics$57,297$50,303 â–¼-46.8%21,3000.0%HealthcareEVAXION AS$54,442$6,668 â–¼-10.9%17,5620.0%SPONSORED ADSAPREAprea Therapeutics$0New Holding137,1740.0%HealthcareXBISPDR S&P Biotech ETF$0$102,184,000 â–¼-100.0%00.0%ETFTERNTerns Pharmaceuticals$0$5,272,000 â–¼-100.0%00.0%HealthcareESTAEstablishment Labs$0$3,179,680 â–¼-100.0%00.0%HealthcareAREAlexandria Real Estate Equities$0$2,321,000 â–¼-100.0%00.0%Real EstateACADACADIA Pharmaceuticals$0$2,226,000 â–¼-100.0%00.0%HealthcareXOMAXOMA Royalty$0$2,180,215 â–¼-100.0%00.0%HealthcareCADLCandel Therapeutics$0$502,250 â–¼-100.0%00.0%HealthcareShowing largest 100 holdings. 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