Stonepine Capital Management, LLC Top Holdings and 13F Report (2021) About Stonepine Capital Management, LLCInvestment ActivityStonepine Capital Management, LLC has $177.26 million in total holdings as of September 30, 2021.Stonepine Capital Management, LLC owns shares of 83 different stocks, but just 28 companies or ETFs make up 80% of its holdings.Approximately 34.27% of the portfolio was purchased this quarter.About 83.42% of the portfolio was sold this quarter.This quarter, Stonepine Capital Management, LLC has purchased 72 new stocks and bought additional shares in 22 stocks.Stonepine Capital Management, LLC sold shares of 31 stocks and completely divested from 13 stocks this quarter.Largest Holdings Evolus $14,185,724ADMA Biologics $14,143,800Verastem $12,795,575TENAX THERAPEUTICS INC $9,603,000NEKTAR THERAPEUTICS $8,422,856 Largest New Holdings this Quarter 90400D108 - Ultragenyx Pharmaceutical $6,334,750 Holding457669307 - Insmed $5,600,000 Holding29014R301 - ELOXX PHARMACEUTICALS INC $5,512,581 HoldingG5960L103 - Medtronic $4,375,000 Holding45579U109 - INDIVIOR PHARMACEUTICALS INC $4,103,000 Holding Largest Purchases this Quarter Ultragenyx Pharmaceutical 225,000 shares (about $6.33M)Insmed 40,000 shares (about $5.60M)ELOXX PHARMACEUTICALS INC 397,160 shares (about $5.51M)Medtronic 50,000 shares (about $4.38M)INDIVIOR PHARMACEUTICALS INC 100,000 shares (about $4.10M) Largest Sales this Quarter ADMA Biologics 500,000 shares (about $5.09M)TENAX THERAPEUTICS INC 315,200 shares (about $4.59M)Zevra Therapeutics 221,299 shares (about $3.17M)Abeona Therapeutics 289,303 shares (about $1.79M)Evolus 168,929 shares (about $1.19M) Sector Allocation Over TimeMap of 500 Largest Holdings ofStonepine Capital Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorEOLSEvolus$14,185,724$1,192,133 ▼-7.8%2,010,1628.0%HealthcareADMAADMA Biologics$14,143,800$5,087,698 ▼-26.5%1,390,0008.0%HealthcareVSTMVerastem$12,795,575$180,789 ▲1.4%3,349,6277.2%HealthcareTENAX THERAPEUTICS INC$9,603,000$4,586,160 ▼-32.3%660,0005.4%COM NEWNEKTAR THERAPEUTICS$8,422,856$2,489,006 ▲41.9%120,6544.8%COM NEWRAREUltragenyx Pharmaceutical$6,334,750$6,334,750 ▲New Holding225,0003.6%HealthcareCAMP4 THERAPEUTICS CORP$6,072,6480.0%1,389,6223.4%COM 13469V AB 4 CAMTEK LTD NOTE 12/0INSMInsmed$5,600,000$5,600,000 ▲New Holding40,0003.2%HealthcareELOXX PHARMACEUTICALS INC$5,512,581$5,512,581 ▲New Holding397,1603.1%COM NEWKAZIA THERAPEUTICS LTD$4,860,1200.0%345,1792.7%SPONSORED ADSMDTMedtronic$4,375,000$4,375,000 ▲New Holding50,0002.5%HealthcareINDIVIOR PHARMACEUTICALS INC$4,103,000$4,103,000 ▲New Holding100,0002.3%COMCRBPCorbus Pharmaceuticals$3,986,500$389,626 ▲10.8%425,0002.2%HealthcareABTAbbott Laboratories$3,800,000$3,800,000 ▲New Holding40,0002.1%HealthcareSATELLOS BIOSCIENCE INC$3,723,291$2,965,946 ▲391.6%491,6242.1%COMZVRAZevra Therapeutics$3,709,772$3,173,427 ▼-46.1%258,7012.1%HealthcareABEOAbeona Therapeutics$3,444,015$1,787,892 ▼-34.2%557,2841.9%HealthcareBSXBoston Scientific$3,250,000$3,250,000 ▲New Holding50,0001.8%HealthcareEDESA BIOTECH INC$3,190,807$2,981,087 ▲1,421.5%456,4391.8%COM NEWBMRNBioMarin Pharmaceutical$3,125,000$3,125,000 ▲New Holding50,0001.8%HealthcareCABACabaletta Bio$2,852,181$2,696,681 ▲1,734.2%917,1001.6%HealthcareAN2 THERAPEUTICS INC$2,670,190$784,821 ▼-22.7%551,6921.5%COMXILIO THERAPEUTICS INC$2,165,023$1,550,351 ▲252.2%225,9941.2%COMADICET BIO INC$2,121,276$203,584 ▲10.6%245,5181.2%COM NEWXERSXeris Biopharma$2,100,000$300,225 ▼-12.5%280,0001.2%HealthcareTELATELA Bio$1,996,820$33,881 ▲1.7%2,662,4271.1%HealthcareAYTUAytu BioPharma$1,962,780$259,359 ▲15.2%912,9211.1%HealthcareCURIS INC$1,729,292$216,265 ▼-11.1%3,312,1851.0%COMHRTXHeron Therapeutics$1,709,468$1,045,096 ▼-37.9%1,490,7871.0%HealthcareSPRUCE BIOSCIENCES INC$1,554,930$1,554,930 ▲New Holding28,7950.9%COM NEWSIBNSiBone$1,500,000$224,460 ▼-13.0%100,0000.8%HealthcareOKYOOKYO Pharma$1,294,494$19,494 ▲1.5%862,9960.7%HealthcareNEUMORA THERAPEUTICS INC.$1,250,000$250,000 ▼-16.7%500,0000.7%COMPASITHEA THERAPEUTICS CORP$1,134,637$706,184 ▲164.8%2,201,4680.6%COM NEWSOL-GEL TECHNOLOGIES LTD$1,072,732$986,730 ▼-47.9%14,4690.6%SHS NEWLUNGPulmonx$1,060,067$61,292 ▲6.1%815,4360.6%HealthcareX4 PHARMACEUTICALS INC$1,050,699$515,195 ▼-32.9%224,9890.6%COM NEWARDXArdelyx$1,050,0000.0%150,0000.6%HealthcareDCTHDelcath Systems$1,000,0000.0%100,0000.6%HealthcareIN8BIO INC$980,355$44,944 ▲4.8%695,2870.6%COM NEWMLTXMoonLake Immunotherapeutics$973,500$973,500 ▲New Holding50,0000.5%HealthcareQUOIN PHARMACEUTICALS LTD$965,512$706,766 ▲273.2%199,4860.5%SPONSORED ADSMXCTMaxCyte$924,475$311,272 ▼-25.2%751,6060.5%HealthcarePHATPhathom Pharmaceuticals$922,358$379,750 ▲70.0%85,0100.5%HealthcareAZITRA INC$886,903$886,903 ▲New Holding5,285,4760.5%COM NEWCONNECT BIOPHARMA HLDGS LTD$866,925$129,125 ▲17.5%364,2540.5%SHSCYBIN INC$854,541$31,596 ▼-3.6%129,2800.5%COM NEWINHIBIKASE THERAPEUTICS INC$804,243$1,138,876 ▼-58.6%396,1790.5%COM NEWZNTLZentalis Pharmaceuticals$783,678$521,458 ▼-40.0%161,5830.4%HealthcareCTMXCytomX Therapeutics$768,750$731,250 ▼-48.8%205,0000.4%HealthcareMNKDMannKind$750,000$798,900 ▼-51.6%250,0000.4%HealthcareNVCTNuvectis Pharma$735,600$735,600 ▲New Holding40,0000.4%HealthcareCRESCENT BIOPHARMA INC.$720,000$810,000 ▼-52.9%40,0000.4%COMPMVPPMV Pharmaceuticals$718,355$230,501 ▼-24.3%536,0860.4%HealthcareORUKA THERAPEUTICS INC$713,775$713,775 ▲New Holding7,5000.4%COMRADIOPHARM THERANOSTICS LTD$670,5000.0%51,000,0000.4%SPONSORED ADSONKURE THERAPEUTICS INC$595,919$8,637 ▼-1.4%130,6840.3%COM CL ANGENFNervGen Pharma$559,657$559,657 ▲New Holding271,6780.3%HealthcareCALCCalciMedica$544,939$544,939 ▲New Holding622,4320.3%HealthcareARVNArvinas$498,600$270,075 ▲118.2%60,0000.3%HealthcareBIOAGE LABS INC$490,200$735,300 ▼-60.0%20,0000.3%COMOPUS GENETICS INC$413,951$131,643 ▲46.6%100,7180.2%COMQT IMAGING HLDGS INC$407,000$407,000 ▲New Holding100,0000.2%COMBOUNDLESS BIO INC$386,488$1,107,719 ▼-74.1%154,5950.2%COMSINTX TECHNOLOGIES INC$332,531$332,531 ▲New Holding209,2050.2%COM NEWCELLECTAR BIOSCIENCES INC$290,649$290,649 ▲New Holding104,5500.2%COM NEWEUPRAXIA PHARMACEUTICALS INC$287,476$287,476 ▲New Holding43,4910.2%COM 298736 AL 3 EURONET WORLDWIDE INC NOTE 0.750% 3/1SAB BIOTHERAPEUTICS INC$285,757$90,757 ▲46.5%73,2710.2%COM NEWADLAI NORTYE LTD$278,956$278,956 ▲New Holding24,2570.2%SPONSORED ADSSENSEONICS HLDGS INC$276,502$276,502 ▲New Holding48,6800.2%COMPLRXPliant Therapeutics$262,813$6,712 ▲2.6%230,5380.1%HealthcareCDXSCodexis$247,836$696,830 ▼-73.8%109,6620.1%HealthcarePOCIPrecision Optics$236,589$273,411 ▼-53.6%46,3900.1%HealthcareUPSTREAM BIO INC$231,349$10,851 ▼-4.5%33,4320.1%COMREIN THERAPEUTICS INC$226,760$226,760 ▲New Holding218,0380.1%COM NEWCNS PHARMACEUTICALS INC$198,719$92,861 ▼-31.8%41,5730.1%COMHUMAHumacyte$180,506$180,506 ▲New Holding231,2990.1%HealthcareKALARIS THERAPEUTICS INC$122,597$39,569 ▲47.7%30,1220.1%COMPROCESSA PHARMACEUTICALS INC$105,6000.0%55,0000.1%COM SHSBIOATLA INC$68,028$68,028 ▲New Holding16,4320.0%COM NEWCGENCompugen$67,168$156,033 ▼-69.9%31,3870.0%HealthcareOVIDOvid Therapeutics$57,297$50,303 ▼-46.8%21,3000.0%HealthcareEVAXION AS$54,442$6,668 ▼-10.9%17,5620.0%SPONSORED ADSXBISPDR S&P Biotech ETF$0$102,184,000 ▼-100.0%00.0%ETFTERNTerns Pharmaceuticals$0$5,272,000 ▼-100.0%00.0%HealthcareESTAEstablishment Labs$0$3,179,680 ▼-100.0%00.0%HealthcareAREAlexandria Real Estate Equities$0$2,321,000 ▼-100.0%00.0%Real EstateACADACADIA Pharmaceuticals$0$2,226,000 ▼-100.0%00.0%HealthcareXOMAXOMA Royalty$0$2,180,215 ▼-100.0%00.0%HealthcareSURROZEN INC$0$961,436 ▼-100.0%00.0%COM NEWVERRICA PHARMACEUTICALS INC$0$527,598 ▼-100.0%00.0%COM SHSCADLCandel Therapeutics$0$502,250 ▼-100.0%00.0%HealthcareJANXJanux Therapeutics$0$278,000 ▼-100.0%00.0%HealthcareOABIOmniAb$0$257,551 ▼-100.0%00.0%HealthcareELDNEledon Pharmaceuticals$0$107,800 ▼-100.0%00.0%HealthcareBCABBioAtla$0$10,527 ▼-100.0%00.0%HealthcareShowing largest 100 holdings. 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