Luca Issi Analyst PerformanceSenior Biotechnology Analyst at Royal Bank Of CanadaLuca Issi is a stock analyst at Royal Bank Of Canada focused in the healthcare sector, covering 30 publicly traded companies. Over the past year, Luca Issi has issued 58 stock ratings, including buy and hold recommendations. While full access to Luca Issi's proprietary MarketBeat Analyst Ranking is reserved for MarketBeat All Access subscribers, the rating is updated daily to reflect the most recent analyst activity. This profile highlights Luca Issi's coverage history, rating activity, and performance tendencies - helping individual investors make more informed trading decisions. Analyst Rankings, Coverage, and Performance StatisticsAnalyst RankingSubscribe to MarketBeat All Access for the analyst's recommendation accuracy rating MarketBeatAverage Return00.00% 12-Month ROISuccess Rate00.00% Profitable RatingsTotal Ratings94 Last 1 YearsBuy Recommendations62.77% 59 Buy RatingsCompanies Covered30 Unique Companies Ratings Distribution94RatingsDistribution of strong buy, buy, hold, and sell ratings by Luca Issi.RatingPercentageCount Strong Buy0.0%0 ratings Buy62.8%59 ratings Hold37.2%35 ratings Sell0.0%0 ratingsOut of 94 total stock ratings issued by Luca Issi at Royal Bank Of Canada, the majority (62.8%) have been Buy recommendations, followed by 37.2% Hold.Best & Worst CallsBest Call0000.0%ARWRAug 2025Subscribe to MarketBeat All Access to get analyst recommendation ROI.Worst Call000.0%KRROMar 2025Subscribe to MarketBeat All Access to get analyst recommendation ROI.Exchange CoverageExchangePercentageCountNASDAQ96.7% of companies on NASDAQ29 companiesNYSE3.3% of companies on NYSE1 companyLuca Issi, an analyst at Royal Bank Of Canada, currently covers 30 companies listed on NASDAQ and NYSE, with the majority traded on NASDAQ.Coverage FocusSector IconSectorPercentageHealthcare29 companies96.7%Energy1 company3.3%Luca Issi of Royal Bank Of Canada specializes in stock coverage within the Healthcare sector, with additional focus on Energy companies.Coverage IndustriesIndustryPercentageBIOTECHNOLOGY28 companies93.3%PHARMACEUTICALS1 company3.3%ENERGY EQUIPMENT & SERVICES1 company3.3% Luca Issi's Ratings History at Royal Bank Of Canada Custom Range 1 Month 3 Months 6 Months Year-to-Date 1 Year 2 Years 3 Years 4 Years 5 Years All Time Timeframe Start Date End Date All Ratings Strong Buy Buy Hold Sell Rating Recommendation ROI is the percentage between the price on the Report Date to the price 12 months after the report date.Available with a MarketBeat All Access Subscription12-Month ROIUpgrade to All Access to use the All ROI Filter Export CompanyReport DateActionReport Date Price12-MonthPrice TargetRating12-MonthPrice & ROIDetailsMRNAModerna8/19/2026Reiterated Rating$144.21$130.00Sector Perform$0.0000.00% ROIARGXargenex8/18/2026Boost Price Target$987.84$1,100.00Outperform$0.0000.00% ROIASNDAscendis Pharma A/S8/14/2026Boost Price Target$247.75$290.00Outperform$0.0000.00% ROIAMGNAmgen8/5/2026Boost Price Target$390.63$400.00Outperform$0.0000.00% ROIALNYAlnylam Pharmaceuticals7/31/2026Lower Price Target$203.09$350.00Outperform$0.0000.00% ROIDYNDyne Therapeutics7/30/2026Boost Price Target$25.20$35.00Outperform$0.0000.00% ROIARGXargenex7/24/2026Boost Price Target$919.54$1,025.00Outperform$0.0000.00% ROIIONSIonis Pharmaceuticals7/13/2026Lower Price Target$56.83$85.00Outperform$0.0000.00% ROIMRNAModerna7/7/2026Boost Price Target$81.80$45.00Sector Perform$0.0000.00% ROIASNDAscendis Pharma A/S7/7/2026Boost Price Target$267.92$280.00Outperform$0.0000.00% ROI Get the Latest News and Ratings for Your StocksEnter your email address below to receive the latest headlines and analysts' recommendations for your stocks with our free daily email newsletter. AGIOAgios Pharmaceuticals7/7/2026Boost Price Target$37.39$32.00Sector Perform$0.0000.00% ROIRAREUltragenyx Pharmaceutical7/7/2026Boost Price Target$35.89$40.00Outperform$0.0000.00% ROIBMRNBioMarin Pharmaceutical7/7/2026Lower Price Target$59.50$62.00Sector Perform$0.0000.00% ROIARGXargenex7/7/2026Boost Price Target$925.81$945.00Outperform$0.0000.00% ROIQUREuniQure6/18/2026Boost Price Target$48.16$65.00Outperform$0.0000.00% ROIARWRArrowhead Pharmaceuticals5/8/2026Boost Price Target$74.04$87.00Outperform$0.0000.00% ROIBMRNBioMarin Pharmaceutical5/5/2026Reiterated Rating$54.43$66.00Sector Perform$0.0000.00% ROIMRNAModerna5/4/2026Boost Price Target$46.82$38.00Sector Perform$0.0000.00% ROIALNYAlnylam Pharmaceuticals5/1/2026Lower Price Target$300.78$445.00Outperform$0.0000.00% ROIIONSIonis Pharmaceuticals4/30/2026Boost Price Target$74.76$100.00Outperform$0.0000.00% ROIBBIOBridgeBio Pharma4/9/2026Initiated Coverage$74.14$100.00Outperform$0.0000.00% ROIBBIOBridgeBio Pharma4/8/2026Upgrade$75.52Moderate Buy$0.0000.00% ROIQUREuniQure3/9/2026Upgrade$14.27$35.00Outperform$0.0000.00% ROINTLAIntellia Therapeutics3/3/2026Boost Price Target$14.00$15.00Sector Perform$0.0000.00% ROIASNDAscendis Pharma A/S3/2/2026Boost Price Target$242.09$275.00Outperform$0.0000.00% ROIQUREuniQure3/2/2026Downgrade$10.37$11.00Sector Perform$0.0000.00% ROIARGXargenex2/27/2026Lower Price Target$773.97$890.00Outperform$0.0000.00% ROIQUREuniQure2/26/2026Reiterated Rating$17.11$11.00Sector Perform$0.0000.00% ROIIONSIonis Pharmaceuticals2/25/2026Reiterated Rating$81.09Outperform$0.0000.00% ROIBEAMBeam Therapeutics2/25/2026Boost Price Target$32.40$26.00Sector Perform$0.0000.00% ROIMRNAModerna2/17/2026Boost Price Target$43.20$30.00Sector Perform$0.0000.00% ROIASNDAscendis Pharma A/S1/20/2026Boost Price Target$205.83$250.00Outperform$0.0000.00% ROIALNYAlnylam Pharmaceuticals1/20/2026Lower Price Target$349.07$465.00Outperform$0.0000.00% ROIMRNAModerna1/12/2026Reiterated Rating$33.85Sector Perform$0.0000.00% ROIIONSIonis Pharmaceuticals12/17/2025Boost Price Target$78.37$95.00Outperform$0.0000.00% ROIARGXargenex12/17/2025Boost Price Target$861.66$925.00Outperform$0.0000.00% ROIARWRArrowhead Pharmaceuticals12/11/2025Boost Price Target$70.05$80.00Outperform$0.0000.00% ROIWVEWAVE Life Sciences12/8/2025Upgrade$18.52$27.00Outperform$0.0000.00% ROIFULCFulcrum Therapeutics12/8/2025Boost Price Target$8.90$10.00Sector Perform$0.0000.00% ROIMRNAModerna11/21/2025Lower Price Target$22.90$25.00Sector Perform$0.0000.00% ROIMILLIONAIRE MASTERCLASS INVITE: Altucher (Ad)James Altucher says Elon Musk is preparing an unprecedented project set to surface on September 25. Altucher is hosting a free masterclass revealing what he says is locked inside a sealed briefcase detailing Musk's plans. Attendees who join early can also access a $1,000 bonus offer included with the presentation.Watch James Altucher's free masterclass before September 25ARWRArrowhead Pharmaceuticals11/19/2025Boost Price Target$40.85$52.00Outperform$0.0000.00% ROIAGIOAgios Pharmaceuticals11/19/2025Downgrade$22.69$28.00Sector Perform$0.0000.00% ROIKRROKorro Bio11/13/2025Downgrade$31.42Sector Perform$0.0000.00% ROICRSPCRISPR Therapeutics11/11/2025Boost Price Target$54.58$50.00Sector Perform$0.0000.00% ROINTLAIntellia Therapeutics11/7/2025Lower Price Target$9.19$9.00Sector Perform$0.0000.00% ROIRGNXREGENXBIO11/7/2025Boost Price Target$11.27$19.00Outperform$0.0000.00% ROIDYNDyne Therapeutics11/6/2025Boost Price Target$17.87$30.00Outperform$0.0000.00% ROIQUREuniQure11/3/2025Lower Price Target$34.29$45.00Outperform$0.0000.00% ROIARGXargenex10/31/2025Boost Price Target$816.27$860.00Outperform$0.0000.00% ROIFULCFulcrum Therapeutics10/30/2025Boost Price Target$9.29$7.00Sector Perform$0.0000.00% ROIIONSIonis Pharmaceuticals10/30/2025Boost Price Target$73.96$82.00Outperform$0.0000.00% ROIBMRNBioMarin Pharmaceutical10/28/2025Reiterated Rating$53.68$66.00Sector Perform$0.0000.00% ROINTLAIntellia Therapeutics10/28/2025Reiterated Rating$14.79$14.00Sector Perform$0.0000.00% ROIRNAAvidity Biosciences10/28/2025Reiterated Rating$70.00$72.00Sector Perform$0.0000.00% ROINTLAIntellia Therapeutics10/28/2025Downgrade$13.96$14.00Sector Perform$0.0000.00% ROIRNAAvidity Biosciences10/28/2025Downgrade$69.93$72.00Sector Perform$0.0000.00% ROIALNYAlnylam Pharmaceuticals9/19/2025Boost Price Target$452.17$500.00Outperform$0.0000.00% ROIIONSIonis Pharmaceuticals9/4/2025Boost Price Target$60.56$80.00Outperform$0.0000.00% ROIARGXargenex8/25/2025Initiated Coverage$660.00$850.00Outperform$0000.0000.00% ROINTLAIntellia Therapeutics8/8/2025Lower Price Target$10.72$21.00Outperform$00.0000.00% ROIASNDAscendis Pharma A/S8/8/2025Boost Price Target$190.21$230.00Outperform$000.0000.00% ROIARWRArrowhead Pharmaceuticals8/8/2025Lower Price Target$16.10$38.00Outperform$00.0000.00% ROIRGNXREGENXBIO8/8/2025Lower Price Target$7.82$17.00Outperform$00.0000.00% ROICRSPCRISPR Therapeutics8/5/2025Boost Price Target$53.14$42.00Sector Perform$00.0000.00% ROIFULCFulcrum Therapeutics7/30/2025Boost Price Target$6.96$5.00Sector Perform$0.0000.00% ROIDYNDyne Therapeutics7/29/2025Lower Price Target$8.94$23.00Outperform$00.0000.00% ROIADVMAdverum Biotechnologies5/15/2025Lower Price Target$1.91$4.00Sector Perform$0.0000.00% ROIALLOAllogene Therapeutics5/14/2025Reiterated Rating$0.90$10.00Outperform$0.0000.00% ROIAPLSApellis Pharmaceuticals5/8/2025Lower Price Target$18.14$18.00Sector Perform$00.0000.00% ROIMRNAModerna5/2/2025Lower Price Target$27.54$28.00Sector Perform$00.0000.00% ROIASNDAscendis Pharma A/S4/16/2025Initiated Coverage$153.92$205.00Outperform$000.0000.00% ROIADVMAdverum Biotechnologies4/16/2025Lower Price Target$3.20$5.00Sector Perform$0.0000.00% ROILXEOLexeo Therapeutics3/25/2025Lower Price Target$3.88$20.00Outperform$0.0000.00% ROIALNYAlnylam Pharmaceuticals3/21/2025Boost Price Target$281.35$330.00Outperform$000.0000.00% ROIKRROKorro Bio3/19/2025Lower Price Target$24.13$95.00Outperform$00.0000.00% ROIOCULOcular Therapeutix3/18/2025Initiated Coverage$7.94$17.00Outperform$0.0000.00% ROISGMOSangamo Therapeutics3/18/2025Reiterated Rating$0.86$2.00Sector Perform$0.0000.00% ROIMGTXMeiraGTx3/17/2025Boost Price Target$7.77$13.00Outperform$0.0000.00% ROIALLOAllogene Therapeutics3/14/2025Reiterated Rating$1.90$10.00Outperform$0.0000.00% ROIFDMT4D Molecular Therapeutics3/3/2025Lower Price Target$4.47$35.00Outperform$0.0000.00% ROIALNYAlnylam Pharmaceuticals2/26/2025Reiterated Rating$249.62$310.00Outperform$000.0000.00% ROIBEAMBeam Therapeutics2/26/2025Boost Price Target$28.85$26.00Sector Perform$00.0000.00% ROIBMRNBioMarin Pharmaceutical2/20/2025Reiterated Rating$68.99$70.00Sector Perform$00.0000.00% ROIIONSIonis Pharmaceuticals2/20/2025Reiterated Rating$32.26$70.00Outperform$00.0000.00% ROIMRNAModerna2/18/2025Reiterated Rating$35.72$40.00Sector Perform$00.0000.00% ROICRSPCRISPR Therapeutics2/12/2025Lower Price Target$42.75$48.00Sector Perform$00.0000.00% ROIARWRArrowhead Pharmaceuticals2/11/2025Reiterated Rating$18.56$42.00Outperform$00.0000.00% ROIALNYAlnylam Pharmaceuticals2/11/2025Reiterated Rating$269.35$300.00Outperform$000.0000.00% ROIRGNXREGENXBIO1/21/2025Reiterated Rating$7.39$30.00Outperform$00.0000.00% ROILXEOLexeo Therapeutics1/21/2025Reiterated Rating$4.93$24.00Outperform$0.0000.00% ROIBezos… DOOMED (Ad)A single FCC filing hints Elon Musk is planning his biggest project yet - bigger than Tesla, SpaceX, and X combined - aimed at the $25 trillion AI industry. James Altucher says the plan could cut Amazon out of the AI race and disrupt Blue Origin, with a key deadline landing September 25.Watch James Altucher's free video breakdown before the September 25 deadline.ALNYAlnylam Pharmaceuticals1/21/2025Reiterated Rating$257.98$300.00Outperform$000.0000.00% ROIQUREuniQure1/21/2025Reiterated Rating$14.50$24.00Outperform$00.0000.00% ROISLBSLB1/21/2025Reiterated Rating$44.09$57.00Outperform$00.0000.00% ROIIONSIonis Pharmaceuticals1/15/2025Reiterated Rating$33.69$70.00Outperform$00.0000.00% ROI Stock Forecasts and Research Tools Today's Analyst Ratings U.S. Ratings U.K. Ratings Canadian Ratings All Upgrades All Downgrades All Initiations All Price Target Changes Top-Rated Stocks Top Rated Stocks Top-Rated Dividend Stocks Top-Rated Small-Cap Stocks Top-Rated Tech Stocks Most-Upgraded Stocks Most-Downgraded Stocks Lowest-Rated Stocks More Ratings Tools Stock Ratings by Issuer Top-Rated Analysts Top-Rated Brokerages Stock Ratings Screener Free Ratings Newsletter Price Forecasts for Popular Stocks Alphabet (Google) Stock ForecastAmazon Stock ForecastApple Stock ForecastMeta (Facebook) Stock ForecastMicrosoft Stock ForecastNetflix Stock ForecastNvidia Stock ForecastTesla Stock Forecast Top Stock Recommendations by BrokerageWall Street ZenCitigroupUBS GroupBarclaysRoyal Bank Of CanadaMorgan StanleyWells Fargo & CompanyJPMorgan Chase & Co.Jefferies Financial GroupThe Goldman Sachs GroupTD CowenPiper SandlerDeutsche Bank AktiengesellschaftBMO Capital MarketsMizuho Unlock superior investment research and tools. 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