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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:COLL NASDAQ:KRYS NASDAQ:PCVX NASDAQ:PTCT On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCOLLCollegium Pharmaceutical$37.32-4.5%$35.00$23.23▼$42.29$1.23B0.63413,714 shs412,936 shsKRYSKrystal Biotech$143.68-0.5%$146.81$122.80▼$207.84$4.18B0.66250,236 shs350,777 shsPCVXVaxcyte$32.17-2.7%$33.16$27.66▼$121.06$4.29B1.041.41 million shs1.47 million shsPTCTPTC Therapeutics$61.09+0.2%$50.27$33.19▼$62.18$4.84B0.531.28 million shs1.76 million shsThe Best High-Yield Dividend Stocks for 2025Discover the 10 Best High-Yield Dividend Stocks for 2025 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCOLLCollegium Pharmaceutical+3.58%-0.43%+3.14%+33.86%+7.90%KRYSKrystal Biotech+5.02%-3.60%+0.52%+5.32%-27.38%PCVXVaxcyte+3.31%+2.83%+10.20%-4.34%-70.89%PTCTPTC Therapeutics+4.51%+5.09%+34.66%+18.92%+88.91%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCOLLCollegium Pharmaceutical$37.32-4.5%$35.00$23.23▼$42.29$1.23B0.63413,714 shs412,936 shsKRYSKrystal Biotech$143.68-0.5%$146.81$122.80▼$207.84$4.18B0.66250,236 shs350,777 shsPCVXVaxcyte$32.17-2.7%$33.16$27.66▼$121.06$4.29B1.041.41 million shs1.47 million shsPTCTPTC Therapeutics$61.09+0.2%$50.27$33.19▼$62.18$4.84B0.531.28 million shs1.76 million shsThe Best High-Yield Dividend Stocks for 2025Discover the 10 Best High-Yield Dividend Stocks for 2025 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCOLLCollegium Pharmaceutical+3.58%-0.43%+3.14%+33.86%+7.90%KRYSKrystal Biotech+5.02%-3.60%+0.52%+5.32%-27.38%PCVXVaxcyte+3.31%+2.83%+10.20%-4.34%-70.89%PTCTPTC Therapeutics+4.51%+5.09%+34.66%+18.92%+88.91%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCOLLCollegium Pharmaceutical 3.00Buy$42.3313.43% UpsideKRYSKrystal Biotech 2.86Moderate Buy$209.0045.46% UpsidePCVXVaxcyte 3.00Buy$106.25230.28% UpsidePTCTPTC Therapeutics 2.53Moderate Buy$69.0012.95% UpsideCurrent Analyst Ratings BreakdownLatest COLL, PTCT, KRYS, and PCVX Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails9/12/2025PCVXVaxcyteThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageNeutral$38.009/3/2025PTCTPTC TherapeuticsCantor FitzgeraldSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOverweight$118.008/22/2025KRYSKrystal BiotechChardan CapitalSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$219.00 ➝ $216.008/22/2025KRYSKrystal BiotechHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$240.008/20/2025PTCTPTC TherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOverweight$79.00 ➝ $73.008/20/2025PTCTPTC TherapeuticsMorgan StanleySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOverweight$76.00 ➝ $71.008/20/2025PTCTPTC TherapeuticsBank of AmericaSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$82.00 ➝ $76.008/11/2025COLLCollegium PharmaceuticalHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong-Buy$44.008/8/2025PTCTPTC TherapeuticsRobert W. BairdSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingSet Price Target$70.008/8/2025PTCTPTC TherapeuticsCowenSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingHold8/8/2025PTCTPTC TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOutperform$60.00 ➝ $63.00(Data available from 9/12/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCOLLCollegium Pharmaceutical$631.45M1.86$11.81 per share3.16$7.10 per share5.26KRYSKrystal Biotech$359.21M11.58$4.62 per share31.13$32.90 per share4.37PCVXVaxcyteN/AN/AN/AN/A$26.52 per shareN/APTCTPTC Therapeutics$806.78M6.02N/AN/A($14.24) per share-4.29Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCOLLCollegium Pharmaceutical$69.19M$1.0435.886.20N/A5.13%97.28%13.87%11/6/2025 (Estimated)KRYSKrystal Biotech$89.16M$4.9229.2014.25N/A40.85%15.21%13.81%11/3/2025 (Estimated)PCVXVaxcyte-$463.93M-$4.11N/AN/AN/AN/A-16.85%-15.92%11/4/2025 (Estimated)PTCTPTC Therapeutics-$363.30M$6.978.76N/AN/A35.65%-106.31%30.61%11/6/2025 (Estimated)Latest COLL, PTCT, KRYS, and PCVX EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025PTCTPTC Therapeutics-$1.07-$0.83+$0.24-$0.83$173.01 million$178.88 million8/6/2025Q2 2025PCVXVaxcyte-$1.12-$1.22-$0.10-$1.22N/AN/A8/4/2025Q2 2025KRYSKrystal Biotech$1.08$1.29+$0.21$1.29$95.42 million$96.04 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCOLLCollegium PharmaceuticalN/AN/AN/AN/AN/AKRYSKrystal BiotechN/AN/AN/AN/AN/APCVXVaxcyteN/AN/AN/AN/AN/APTCTPTC TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCOLLCollegium Pharmaceutical3.271.181.10KRYSKrystal BiotechN/A9.689.33PCVXVaxcyteN/A11.1111.11PTCTPTC TherapeuticsN/A3.623.57Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCOLLCollegium PharmaceuticalN/AKRYSKrystal Biotech86.29%PCVXVaxcyte96.78%PTCTPTC TherapeuticsN/AInsider OwnershipCompanyInsider OwnershipCOLLCollegium Pharmaceutical2.51%KRYSKrystal Biotech13.70%PCVXVaxcyte3.10%PTCTPTC Therapeutics5.50%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCOLLCollegium Pharmaceutical21031.50 million30.71 millionOptionableKRYSKrystal Biotech21028.94 million24.98 millionOptionablePCVXVaxcyte160129.82 million125.80 millionOptionablePTCTPTC Therapeutics1,41079.44 million75.07 millionOptionableCOLL, PTCT, KRYS, and PCVX HeadlinesRecent News About These CompaniesPTC Therapeutics (NASDAQ:PTCT) Director Sells $700,080.00 in StockSeptember 12 at 7:41 AM | insidertrades.comBayforest Capital Ltd Purchases New Shares in PTC Therapeutics, Inc. $PTCTSeptember 12 at 7:17 AM | marketbeat.comEric Pauwels Sells 39,850 Shares of PTC Therapeutics (NASDAQ:PTCT) StockSeptember 11 at 5:42 PM | marketbeat.comPTC Therapeutics, Inc. (PTCT) Launches SUFIANCE for PKUSeptember 11 at 1:28 PM | msn.comInsider Selling: PTC Therapeutics (NASDAQ:PTCT) Insider Sells 39,850 Shares of StockSeptember 10 at 6:00 AM | insidertrades.comAQR Capital Management LLC Boosts Stake in PTC Therapeutics, Inc. $PTCTSeptember 10 at 3:53 AM | marketbeat.comCantor Fitzgerald Keeps Their Buy Rating on PTC Therapeutics (PTCT)September 8, 2025 | theglobeandmail.comPTC Therapeutics, Inc. (PTCT) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference (Transcript)September 8, 2025 | seekingalpha.comPTC Therapeutics, Inc. $PTCT Shares Bought by Parkman Healthcare Partners LLCSeptember 8, 2025 | marketbeat.comPTC Therapeutics, Inc. (NASDAQ:PTCT) Receives $69.00 Consensus Price Target from AnalystsSeptember 8, 2025 | americanbankingnews.comPTC Therapeutics, Inc. (PTCT) Presents At Cantor Global Healthcare Conference 2025 TranscriptSeptember 7, 2025 | seekingalpha.comPTC Therapeutics, Inc. (PTCT) Presents At Wells Fargo 20th Annual Healthcare Conference 2025 TranscriptSeptember 7, 2025 | seekingalpha.comAdage Capital Partners GP L.L.C. Increases Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 7, 2025 | marketbeat.comPTC Therapeutics, Inc. (NASDAQ:PTCT) Receives Average Rating of "Moderate Buy" from AnalystsSeptember 7, 2025 | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Receives "Overweight" Rating from Cantor FitzgeraldSeptember 5, 2025 | marketbeat.comPDT Partners LLC Has $2.06 Million Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 5, 2025 | marketbeat.comCanada Pension Plan Investment Board Purchases 138,800 Shares of PTC Therapeutics, Inc. $PTCTSeptember 5, 2025 | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Director Sells $83,600.05 in StockSeptember 4, 2025 | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Stock Price Up 6.1% - Should You Buy?September 4, 2025 | marketbeat.comMPM Bioimpact LLC Has $22.42 Million Holdings in PTC Therapeutics, Inc. $PTCTSeptember 4, 2025 | marketbeat.comPalo Alto Investors LP Grows Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 4, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeCOLL, PTCT, KRYS, and PCVX Company DescriptionsCollegium Pharmaceutical NASDAQ:COLL$37.32 -1.74 (-4.45%) Closing price 04:00 PM EasternExtended Trading$37.32 0.00 (0.00%) As of 04:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. Its portfolio includes Xtampza ER, an abuse-deterrent, extended-release, and oral formulation of oxycodone for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment; Nucynta ER and Nucynta IR, which are extended-release and immediate-release formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; Belbuca, a buccal film that contains buprenorphine; and Symproic, an oral formulation of naldemedine for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain. The company was formerly known as Collegium Pharmaceuticals, Inc. and changed its name to Collegium Pharmaceutical, Inc. in October 2003. Collegium Pharmaceutical, Inc. was incorporated in 2002 and is headquartered in Stoughton, Massachusetts.Krystal Biotech NASDAQ:KRYS$143.68 -0.68 (-0.47%) Closing price 04:00 PM EasternExtended Trading$144.18 +0.50 (+0.34%) As of 04:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, and commercializes genetic medicines for patients with rare diseases in the United States. It commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). The company also develops KB105, which is in Phase 1/2 clinical trials for treating patients with deficient autosomal recessive congenital ichthyosis; KB104 for treating netherton syndrome; KB407 that is in Phase 1 clinical trials for treating cystic fibrosis; KB707 that is in Phase 1 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.Vaxcyte NASDAQ:PCVX$32.17 -0.89 (-2.69%) Closing price 04:00 PM EasternExtended Trading$32.17 +0.00 (+0.02%) As of 06:41 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.PTC Therapeutics NASDAQ:PTCT$61.09 +0.13 (+0.21%) Closing price 04:00 PM EasternExtended Trading$61.11 +0.02 (+0.03%) As of 07:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders in the United States and internationally. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy; Upstaza to treat aromatic l-amino acid decarboxylas (AADC) deficiency, a central nervous system disorder; Tegsedi and Waylivra for the treatment of rare diseases; and Evrysdi to treat spinal muscular atrophy (SMA) in adults and children. Its development pipeline products include Sepiapterin for the treatment of phenylketonuria; PTC518 splicing platform, which is being developed for the treatment of Huntington's disease; and ferroptosis and inflammation platforms, including vatiquinone to treat Friedreich ataxia and utreloxastat for the treatment of amyotrophic lateral sclerosis. The company distributes its products through third-party distributors. It has collaborations with F. Hoffman-La Roche Ltd, Hoffman-La Roche Inc., the SMA Foundation, National Taiwan University, Akcea Therapeutics, Inc., and Shiratori Pharmaceutical Co., Ltd. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey. 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