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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:AXSMNASDAQ:DYNNASDAQ:LEGNNASDAQ:NUVL On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAXSMAxsome Therapeutics$104.92+0.3%$106.72$64.11▼$139.13$5.17B0.46687,285 shs485,793 shsDYNDyne Therapeutics$11.82-3.4%$10.30$6.36▼$47.45$1.36B1.191.63 million shs1.13 million shsLEGNLegend Biotech$28.75-0.8%$31.79$27.34▼$60.87$5.28B0.21.29 million shs2.15 million shsNUVLNuvalent$73.63-1.5%$70.99$55.54▼$113.51$5.37B1.42492,375 shs532,918 shs7 Stocks to Buy And Hold ForeverEnter your email address and we'll send you MarketBeat's list of seven stocks and why their long-term outlooks are very promising. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAXSMAxsome Therapeutics0.00%-0.14%-6.52%-17.74%+39.50%DYNDyne Therapeutics0.00%+1.11%-1.42%-13.15%-61.97%LEGNLegend Biotech0.00%-0.55%-15.34%-17.88%-31.68%NUVLNuvalent0.00%+0.19%-3.41%-1.80%+11.49%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAXSMAxsome Therapeutics4.8084 of 5 stars4.53.00.04.52.64.20.6DYNDyne Therapeutics3.0682 of 5 stars4.51.00.00.02.83.30.0LEGNLegend Biotech3.3307 of 5 stars4.52.00.00.03.51.70.6NUVLNuvalent2.4552 of 5 stars3.52.00.00.02.93.30.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAXSMAxsome Therapeutics 3.07Buy$172.1464.07% UpsideDYNDyne Therapeutics 3.07Buy$47.15298.93% UpsideLEGNLegend Biotech 2.91Moderate Buy$76.20165.04% UpsideNUVLNuvalent 2.90Moderate Buy$115.5056.87% UpsideCurrent Analyst Ratings BreakdownLatest DYN, LEGN, NUVL, and AXSM Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/29/2025DYNDyne TherapeuticsEvercore ISISubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOutperform$46.005/22/2025AXSMAxsome TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$180.00 ➝ $180.005/14/2025AXSMAxsome TherapeuticsCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeStrong-Buy5/14/2025LEGNLegend BiotechTruist FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$88.00 ➝ $71.005/14/2025LEGNLegend BiotechCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOverweight ➝ Overweight$55.00 ➝ $55.005/9/2025DYNDyne TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$46.00 ➝ $38.005/9/2025DYNDyne TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$50.00 ➝ $50.005/7/2025AXSMAxsome TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$200.00 ➝ $180.005/6/2025AXSMAxsome TherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOverweight ➝ Overweight$160.00 ➝ $165.005/6/2025AXSMAxsome TherapeuticsRobert W. BairdSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$160.00 ➝ $162.004/29/2025AXSMAxsome TherapeuticsRoyal Bank of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$190.00 ➝ $193.00(Data available from 6/1/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAXSMAxsome Therapeutics$432.16M11.95N/AN/A$1.18 per share88.92DYNDyne TherapeuticsN/AN/AN/AN/A$1.49 per shareN/ALEGNLegend Biotech$728.30M7.25N/AN/A$6.88 per share4.18NUVLNuvalentN/AN/AN/AN/A$10.94 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAXSMAxsome Therapeutics-$287.22M-$5.77N/A37.21N/A-74.47%-223.51%-39.88%8/4/2025 (Estimated)DYNDyne Therapeutics-$235.94M-$3.59N/AN/AN/AN/A-57.46%-51.62%8/11/2025 (Estimated)LEGNLegend Biotech-$518.25M-$0.59N/AN/AN/A-66.92%-29.69%-19.45%8/8/2025 (Estimated)NUVLNuvalent-$126.22M-$4.39N/AN/AN/AN/A-28.63%-27.15%8/14/2025 (Estimated)Latest DYN, LEGN, NUVL, and AXSM EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/13/2025Q1 2025LEGNLegend Biotech-$0.40-$0.07+$0.33-$0.27$190.83 million$195.05 million5/8/2025Q1 2025DYNDyne Therapeutics-$0.88-$1.05-$0.17-$1.05N/AN/A5/8/2025Q1 2025NUVLNuvalent-$1.14-$1.18-$0.04-$1.18N/AN/A3/11/2025Q4 2024LEGNLegend Biotech-$0.39$0.07+$0.46$0.07$179.00 million$186.50 million3/4/2025Q4 2024DYNDyne Therapeutics-$0.92-$0.88+$0.04-$0.88N/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAXSMAxsome TherapeuticsN/AN/AN/AN/AN/ADYNDyne TherapeuticsN/AN/AN/AN/AN/ALEGNLegend BiotechN/AN/AN/AN/AN/ANUVLNuvalentN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAXSMAxsome Therapeutics3.222.112.04DYNDyne TherapeuticsN/A17.0217.02LEGNLegend Biotech0.274.984.90NUVLNuvalentN/A23.0723.07Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAXSMAxsome Therapeutics81.49%DYNDyne Therapeutics96.68%LEGNLegend Biotech70.89%NUVLNuvalent97.26%Insider OwnershipCompanyInsider OwnershipAXSMAxsome Therapeutics22.30%DYNDyne Therapeutics14.14%LEGNLegend Biotech0.02%NUVLNuvalent12.52%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAXSMAxsome Therapeutics38049.24 million37.84 millionOptionableDYNDyne Therapeutics100113.67 million80.63 millionOptionableLEGNLegend Biotech1,070183.76 million182.60 millionOptionableNUVLNuvalent4071.81 million62.16 millionOptionableDYN, LEGN, NUVL, and AXSM HeadlinesRecent News About These CompaniesNuvalent, Inc. Reports Q1 2025 Financial ResultsMay 31 at 12:07 AM | tipranks.comNuvalent (NASDAQ:NUVL) Stock Price Up 6.2% - Time to Buy?May 30 at 2:31 PM | marketbeat.comSquarepoint Ops LLC Reduces Position in Nuvalent, Inc. (NASDAQ:NUVL)May 29 at 4:19 AM | marketbeat.comNuvalent, Inc. (NASDAQ:NUVL) Shares Sold by Polar Asset Management Partners Inc.May 28, 2025 | marketbeat.comVoloridge Investment Management LLC Has $13.37 Million Holdings in Nuvalent, Inc. (NASDAQ:NUVL)May 26, 2025 | marketbeat.comTwo Sigma Advisers LP Decreases Stake in Nuvalent, Inc. (NASDAQ:NUVL)May 25, 2025 | marketbeat.comTwo Sigma Investments LP Reduces Stock Position in Nuvalent, Inc. (NASDAQ:NUVL)May 25, 2025 | marketbeat.comNuvalent’s SWOT analysis: cancer drug developer’s stock faces pivotal yearMay 24, 2025 | investing.comTwinbeech Capital LP Invests $2.32 Million in Nuvalent, Inc. (NASDAQ:NUVL)May 24, 2025 | marketbeat.comDeutsche Bank AG Has $2.79 Million Stock Holdings in Nuvalent, Inc. (NASDAQ:NUVL)May 24, 2025 | marketbeat.comMan Group plc Purchases 41,447 Shares of Nuvalent, Inc. (NASDAQ:NUVL)May 23, 2025 | marketbeat.comNuvalent, Inc. (NASDAQ:NUVL) Receives Average Rating of "Moderate Buy" from BrokeragesMay 23, 2025 | marketbeat.comWoodline Partners LP Grows Stake in Nuvalent, Inc. (NASDAQ:NUVL)May 22, 2025 | marketbeat.comNuvalent, Inc. (NASDAQ:NUVL) Shares Acquired by Bank of America Corp DEMay 22, 2025 | marketbeat.comBNP Paribas Financial Markets Acquires Shares of 17,366 Nuvalent, Inc. (NASDAQ:NUVL)May 22, 2025 | marketbeat.comVestal Point Capital LP Makes New $46.97 Million Investment in Nuvalent, Inc. (NASDAQ:NUVL)May 21, 2025 | marketbeat.comSoleus Capital Management L.P. Has $8.17 Million Stock Holdings in Nuvalent, Inc. (NASDAQ:NUVL)May 21, 2025 | marketbeat.comRafferty Asset Management LLC Increases Stake in Nuvalent, Inc. (NASDAQ:NUVL)May 21, 2025 | marketbeat.comTema Etfs LLC Acquires New Stake in Nuvalent, Inc. (NASDAQ:NUVL)May 20, 2025 | marketbeat.comSandia Investment Management LP Boosts Holdings in Nuvalent, Inc. (NASDAQ:NUVL)May 19, 2025 | marketbeat.comPolar Asset Management Partners Inc. Sells 43,200 Shares of Nuvalent, Inc. (NASDAQ:NUVL)May 19, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All HeadlinesBullish NVIDIA Market Set to Surge 50% Ahead of Q1 EarningsBy Thomas Hughes | May 27, 2025View Bullish NVIDIA Market Set to Surge 50% Ahead of Q1 Earnings3 Defense Stocks That Will Profit From a Golden DomeBy Chris Markoch | May 30, 2025View 3 Defense Stocks That Will Profit From a Golden DomeAfter Earnings Beats, These 3 Stocks Are on Analysts’ RadarsBy Leo Miller | May 20, 2025View After Earnings Beats, These 3 Stocks Are on Analysts’ RadarsStrategists Say Hold: Stocks May Beat the 'Sell in May' TrendBy Jeffrey Neal Johnson | May 9, 2025View Strategists Say Hold: Stocks May Beat the 'Sell in May' TrendWingstop Stock Jumps on Q1 Beat, Expansion OutlookBy Jeffrey Neal Johnson | May 4, 2025View Wingstop Stock Jumps on Q1 Beat, Expansion OutlookDYN, LEGN, NUVL, and AXSM Company DescriptionsAxsome Therapeutics NASDAQ:AXSM$104.92 +0.28 (+0.27%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$105.00 +0.08 (+0.08%) As of 05/30/2025 06:49 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.Dyne Therapeutics NASDAQ:DYN$11.82 -0.42 (-3.43%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$11.96 +0.15 (+1.23%) As of 05/30/2025 04:21 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Dyne Therapeutics, Inc., a clinical-stage muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. Dyne Therapeutics, Inc. was incorporated in 2017 and is headquartered in Waltham, Massachusetts.Legend Biotech NASDAQ:LEGN$28.75 -0.22 (-0.76%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$28.90 +0.15 (+0.50%) As of 05/30/2025 07:22 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Legend Biotech Corporation, a clinical-stage biopharmaceutical company, through its subsidiaries, engages in the discovery, development, manufacturing, and commercialization of novel cell therapies for oncology and other indications in the United States, China, and internationally. Its lead product candidate, LCAR- B38M, is a chimeric antigen receptor for the treatment of multiple myeloma (MM). The company also has a portfolio of earlier-stage autologous CAR-T product candidates targeting various cancers, including Non-Hodgkins Lymphoma, acute lymphoblastic leukemia, gastric cancer, esophageal cancer, pancreatic cancer, colorectal cancer, hepatocellular carcinoma, small cell lung cancer, and non-small cell lung cancer. It has collaboration and license agreement with Janssen Biotech, Inc. for the development and commercialization of ciltacabtagene autoleucel. The company was founded in 2014 and is based in Somerset, New Jersey. Legend Biotech Corporation is a subsidiary of Genscript Biotech Corporation.Nuvalent NASDAQ:NUVL$73.63 -1.13 (-1.51%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$74.58 +0.95 (+1.30%) As of 05/30/2025 04:29 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts. 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