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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$128.57
-0.8%
$118.06
$75.56
$139.13
$6.40B0.52721,602 shs46,458 shs
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$26.38
-0.9%
$32.62
$25.95
$41.61
$1.52B0.79701,600 shs115,932 shs
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
$33.20
-1.6%
$34.37
$27.34
$47.79
$6.13B0.231.43 million shs284,616 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$43.51
-1.0%
$34.08
$27.66
$118.54
$5.65B1.121.79 million shs272,244 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
+4.91%+9.16%+10.96%+15.45%+49.92%
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
-0.78%+0.26%-18.06%-26.90%-24.99%
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
+1.47%+4.69%-0.47%-19.96%-24.92%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
+2.54%+7.85%+41.74%+17.58%-61.95%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$128.57
-0.8%
$118.06
$75.56
$139.13
$6.40B0.52721,602 shs46,458 shs
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$26.38
-0.9%
$32.62
$25.95
$41.61
$1.52B0.79701,600 shs115,932 shs
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
$33.20
-1.6%
$34.37
$27.34
$47.79
$6.13B0.231.43 million shs284,616 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$43.51
-1.0%
$34.08
$27.66
$118.54
$5.65B1.121.79 million shs272,244 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
+4.91%+9.16%+10.96%+15.45%+49.92%
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
-0.78%+0.26%-18.06%-26.90%-24.99%
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
+1.47%+4.69%-0.47%-19.96%-24.92%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
+2.54%+7.85%+41.74%+17.58%-61.95%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
3.00
Buy$177.9338.40% Upside
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
2.90
Moderate Buy$45.5672.69% Upside
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
2.73
Moderate Buy$69.25108.62% Upside
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
2.75
Moderate Buy$106.25144.22% Upside

Current Analyst Ratings Breakdown

Latest HRMY, AXSM, LEGN, and PCVX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
10/15/2025
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
UBS Group
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetBuy$50.00 ➝ $43.00
10/14/2025
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
Weiss Ratings
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Reiterated RatingHold (C-)
10/14/2025
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
Weiss Ratings
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Reiterated RatingSell (D-)
10/9/2025
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetOverweight$78.00 ➝ $76.00
10/8/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
Weiss Ratings
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Reiterated RatingSell (D-)
10/8/2025
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
Weiss Ratings
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Reiterated RatingSell (D-)
10/7/2025
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
Cantor Fitzgerald
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Initiated CoverageOverweight$40.00
10/1/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
B. Riley
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Initiated CoverageBuy$179.00
9/30/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
B. Riley
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Initiated CoverageBuy$179.00
9/27/2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
Weiss Ratings
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Reiterated RatingSell (D-)
9/27/2025
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
Weiss Ratings
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingHold (C)
(Data available from 10/16/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$495.03M12.96N/AN/A$1.18 per share108.95
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$772.53M1.96$2.90 per share9.11$11.56 per share2.28
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
$627.24M9.77N/AN/A$5.70 per share5.82
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/A$26.52 per shareN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$287.22M-$5.07N/A45.59N/A-49.88%-283.22%-33.06%11/3/2025 (Estimated)
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$145.49M$3.108.518.480.3323.44%26.34%17.71%11/4/2025 (Estimated)
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
-$177.03M-$0.88N/AN/AN/A-40.83%-32.00%-20.07%11/11/2025 (Estimated)
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$463.93M-$4.11N/AN/AN/AN/A-16.85%-15.92%11/4/2025 (Estimated)

Latest HRMY, AXSM, LEGN, and PCVX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
11/11/2025Q3 2025
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
-$0.08N/AN/AN/A$277.91 millionN/A
11/4/2025Q3 2025
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$0.83N/AN/AN/AN/AN/A
11/4/2025Q3 2025
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$1.23N/AN/AN/AN/AN/A
11/3/2025Q3 2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$0.80N/AN/AN/A$162.96 millionN/A
8/11/2025Q2 2025
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
-$0.22-$0.34-$0.12-$0.34$237.49 million$255.06 million
8/6/2025Q2 2025
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$1.12-$1.22-$0.10-$1.22N/AN/A
8/5/2025Q2 2025
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
$0.78$0.68-$0.10$0.68$204.37 million$200.49 million
8/4/2025Q2 2025
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
-$1.00-$0.92+$0.08-$0.97$140.02 million$150.04 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
N/AN/AN/AN/AN/A
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
N/AN/AN/AN/AN/A
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
N/AN/AN/AN/AN/A
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
1.66
1.57
1.51
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
0.20
3.84
3.80
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
0.30
4.71
4.57
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/A
11.11
11.11

Institutional Ownership

CompanyInstitutional Ownership
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
81.49%
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
86.23%
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
70.89%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
96.78%

Insider Ownership

CompanyInsider Ownership
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
22.30%
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
23.60%
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
0.02%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
3.10%
CompanyEmployeesShares OutstandingFree FloatOptionable
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
38049.90 million38.77 millionOptionable
Harmony Biosciences Holdings, Inc. stock logo
HRMY
Harmony Biosciences
20057.53 million43.96 millionOptionable
Legend Biotech Corporation Sponsored ADR stock logo
LEGN
Legend Biotech
2,609184.57 million184.53 millionOptionable
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
160129.82 million125.80 millionOptionable

Recent News About These Companies

Weiss Ratings Reiterates "Sell (D-)" Rating for Vaxcyte (NASDAQ:PCVX)
Vaxcyte's (PCVX) Sell (D-) Rating Reiterated at Weiss Ratings
Vaxcyte (NASDAQ:PCVX) Shares Up 4.6% - Time to Buy?
Vaxcyte Signs 15-Year Agreement with Patheon
111 Capital Takes Position in Vaxcyte, Inc. $PCVX
What Does Wall Street Think About Vaxcyte (PCVX)?
Strs Ohio Buys Shares of 16,600 Vaxcyte, Inc. $PCVX

New MarketBeat Followers Over Time

Media Sentiment Over Time

Axsome Therapeutics stock logo

Axsome Therapeutics NASDAQ:AXSM

$128.56 -1.02 (-0.78%)
As of 10:44 AM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

Harmony Biosciences stock logo

Harmony Biosciences NASDAQ:HRMY

$26.38 -0.25 (-0.94%)
As of 10:44 AM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare and other neurological diseases in the United States. The company offers WAKIX (pitolisant), a molecule with a novel mechanism of action for the treatment of excessive daytime sleepiness in adult patients with narcolepsy. It also offers HBS-102, a melanin-concentrating hormone receptor 1 for MCH neurons. The company was formerly known as Harmony Biosciences II, Inc. and changed its name to Harmony Biosciences Holdings, Inc. in February 2020. Harmony Biosciences Holdings, Inc. was incorporated in 2017 and is headquartered in Plymouth Meeting, Pennsylvania.

Legend Biotech stock logo

Legend Biotech NASDAQ:LEGN

$33.20 -0.53 (-1.56%)
As of 10:44 AM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Legend Biotech Corporation, a clinical-stage biopharmaceutical company, through its subsidiaries, engages in the discovery, development, manufacturing, and commercialization of novel cell therapies for oncology and other indications in the United States, China, and internationally. Its lead product candidate, LCAR- B38M, is a chimeric antigen receptor for the treatment of multiple myeloma (MM). The company also has a portfolio of earlier-stage autologous CAR-T product candidates targeting various cancers, including Non-Hodgkins Lymphoma, acute lymphoblastic leukemia, gastric cancer, esophageal cancer, pancreatic cancer, colorectal cancer, hepatocellular carcinoma, small cell lung cancer, and non-small cell lung cancer. It has collaboration and license agreement with Janssen Biotech, Inc. for the development and commercialization of ciltacabtagene autoleucel. The company was founded in 2014 and is based in Somerset, New Jersey. Legend Biotech Corporation is a subsidiary of Genscript Biotech Corporation.

Vaxcyte stock logo

Vaxcyte NASDAQ:PCVX

$43.50 -0.44 (-0.99%)
As of 10:44 AM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.