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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ACTUNASDAQ:GLSINASDAQ:KPTINASDAQ:LYEL On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACTUActuate Therapeutics$11.36+7.5%$8.88$5.51▼$11.99$222.88MN/A49,016 shs276,732 shsGLSIGreenwich LifeSciences$9.81-1.1%$9.66$8.06▼$18.75$131.14M1.7446,460 shs18,251 shsKPTIKaryopharm Therapeutics$4.30-5.1%$5.03$3.51▼$17.40$37.15M0.3382,106 shs112,584 shsLYELLyell Immunopharma$0.41+1.9%$0.44$0.39▼$2.80$118.61M-0.251.03 million shs865,368 shs10 "Recession Proof" Stocks That Will Thrive in Any MarketWhich stocks are likely to thrive in today's challenging market? Enter your email address and we'll send you MarketBeat's list of ten stocks that will drive in any economic environment.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACTUActuate Therapeutics+7.47%+9.97%+23.48%+56.91%+1,135,999,900.00%GLSIGreenwich LifeSciences-1.11%0.00%-2.87%-19.72%-25.51%KPTIKaryopharm Therapeutics-5.08%-6.32%-36.30%-45.91%-70.21%LYELLyell Immunopharma+1.92%-2.10%-13.87%-42.42%-84.01%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationACTUActuate TherapeuticsN/AN/AN/AN/AN/AN/AN/AN/AGLSIGreenwich LifeSciences2.0535 of 5 stars3.50.00.00.03.33.30.0KPTIKaryopharm Therapeutics3.9067 of 5 stars3.50.00.04.63.02.50.6LYELLyell Immunopharma2.2082 of 5 stars2.80.00.00.01.95.01.3Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceACTUActuate Therapeutics 3.00Buy$20.5080.46% UpsideGLSIGreenwich LifeSciences 3.00Buy$39.00297.55% UpsideKPTIKaryopharm Therapeutics 3.00Buy$43.20904.65% UpsideLYELLyell Immunopharma 1.50Reduce$1.00144.32% UpsideCurrent Analyst Ratings BreakdownLatest KPTI, ACTU, LYEL, and GLSI Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/13/2025KPTIKaryopharm TherapeuticsRoyal Bank of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$34.00 ➝ $33.005/13/2025KPTIKaryopharm TherapeuticsBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$5.00 ➝ $10.005/13/2025KPTIKaryopharm TherapeuticsRobert W. BairdSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$54.00 ➝ $42.004/22/2025ACTUActuate TherapeuticsCraig HallumSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$21.004/21/2025GLSIGreenwich LifeSciencesHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$38.00 ➝ $39.004/16/2025LYELLyell ImmunopharmaHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingNeutral ➝ Neutral$1.00 ➝ $1.003/17/2025ACTUActuate TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$20.003/13/2025LYELLyell ImmunopharmaHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingNeutral ➝ Neutral$1.00 ➝ $1.003/3/2025KPTIKaryopharm TherapeuticsRobert W. BairdSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$75.00 ➝ $54.00(Data available from 5/31/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookACTUActuate TherapeuticsN/AN/AN/AN/AN/AN/AGLSIGreenwich LifeSciencesN/AN/AN/AN/A$0.52 per shareN/AKPTIKaryopharm Therapeutics$142.13M0.26N/AN/A($1.47) per share-2.93LYELLyell Immunopharma$65K1,859.72N/AN/A$2.60 per share0.16Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateACTUActuate Therapeutics-$24.75MN/A0.00∞N/AN/AN/AN/AN/AGLSIGreenwich LifeSciences-$8.89M-$1.26N/AN/AN/AN/A-185.12%-164.27%8/12/2025 (Estimated)KPTIKaryopharm Therapeutics-$143.10M-$13.26N/AN/AN/A-52.62%N/A-39.58%8/5/2025 (Estimated)LYELLyell Immunopharma-$234.63M-$1.25N/AN/AN/A-323,792.09%-34.64%-30.02%8/6/2025 (Estimated)Latest KPTI, ACTU, LYEL, and GLSI EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/20/2025Q1 2025GLSIGreenwich LifeSciences-$0.24-$0.25-$0.01-$0.25N/AN/A5/15/2025Q1 2025ACTUActuate Therapeutics-$0.26-$0.32-$0.06-$0.32N/AN/A5/13/2025Q1 2025LYELLyell Immunopharma-$0.19-$0.18+$0.01-$0.18N/A$0.01 million5/12/2025Q1 2025KPTIKaryopharm Therapeutics-$4.21-$2.77+$1.44-$2.77$35.12 million$30.02 million4/15/2025Q4 2024GLSIGreenwich LifeSciences-$0.21-$0.61-$0.40-$0.61N/AN/A3/12/2025Q4 2024LYELLyell Immunopharma-$0.20-$0.72-$0.52-$0.72N/A$0.01 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthACTUActuate TherapeuticsN/AN/AN/AN/AN/AGLSIGreenwich LifeSciencesN/AN/AN/AN/AN/AKPTIKaryopharm TherapeuticsN/AN/AN/AN/AN/ALYELLyell ImmunopharmaN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioACTUActuate TherapeuticsN/A1.681.68GLSIGreenwich LifeSciencesN/A6.916.91KPTIKaryopharm TherapeuticsN/A1.702.93LYELLyell ImmunopharmaN/A13.4313.43Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipACTUActuate TherapeuticsN/AGLSIGreenwich LifeSciences4.16%KPTIKaryopharm Therapeutics66.44%LYELLyell Immunopharma66.05%Insider OwnershipCompanyInsider OwnershipACTUActuate Therapeutics69.34%GLSIGreenwich LifeSciences51.67%KPTIKaryopharm Therapeutics2.75%LYELLyell Immunopharma25.10%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableACTUActuate Therapeutics1019.62 millionN/AN/AGLSIGreenwich LifeSciences313.37 million6.35 millionNot OptionableKPTIKaryopharm Therapeutics3808.64 million122.72 millionOptionableLYELLyell Immunopharma270295.34 million218.83 millionOptionableKPTI, ACTU, LYEL, and GLSI HeadlinesRecent News About These CompaniesLyell Immunopharma trading halted, news pendingMay 31 at 1:49 AM | msn.comvenBio Partners LLC Makes New Investment in Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 22, 2025 | marketbeat.comJacobs Levy Equity Management Inc. Acquires New Holdings in Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 19, 2025 | marketbeat.comLyell Immunopharma, Inc: Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2025May 17, 2025 | finanznachrichten.deOrbimed Advisors LLC Decreases Stock Position in Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 15, 2025 | marketbeat.comLyell Immunopharma Advances CAR T-Cell Therapy PipelineMay 14, 2025 | tipranks.comLyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2025May 13, 2025 | globenewswire.comForesite Capital Management V LLC Invests $5.21 Million in Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 12, 2025 | marketbeat.comAlmitas Capital LLC Takes Position in Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 4, 2025 | marketbeat.comRenaissance Technologies LLC Purchases 1,414,746 Shares of Lyell Immunopharma, Inc. (NASDAQ:LYEL)May 3, 2025 | marketbeat.comLyell Immunopharma Announces Oral Presentation of New Clinical Data from the Phase 1/2 Trial of LYL314 for the Treatment of Large B-cell Lymphoma at the International Conference on Malignant Lymphoma (ICML) 2025May 1, 2025 | globenewswire.comLyell Immunopharma (LYEL) Projected to Post Earnings on MondayApril 30, 2025 | marketbeat.comLyell Immunopharma announces FDA granted RMAT designation to LYL314April 17, 2025 | markets.businessinsider.comWhy Lyell Immunopharma, Inc.’s (LYEL) Stock Is Up 7.22%April 16, 2025 | aaii.comLyell Immunopharma Receives Regenerative Medicine Advanced Therapy (RMAT) Designation for LYL314 for the Treatment of Relapsed and/or Refractory Large B-Cell LymphomaApril 15, 2025 | globenewswire.comCAR-T developer Lyell lays off 73 ImmPact staffers, shutters LA facility shortly after acquisitionApril 8, 2025 | fiercepharma.comLyell Cuts 73 Employees as Part of LA Site ClosureApril 7, 2025 | biospace.comOtis W. Brawley Buys 35,640 Shares of Lyell Immunopharma, Inc. (NASDAQ:LYEL) StockApril 3, 2025 | insidertrades.comBank of America Securities Keeps Their Sell Rating on Lyell Immunopharma (LYEL)March 28, 2025 | markets.businessinsider.comIs Lyell Immunopharma, Inc. (LYEL) the Cheapest Stock Insiders Are Buying In March?March 28, 2025 | insidermonkey.comWhy Lyell Immunopharma, Inc.’s (LYEL) Stock Is Up 20.28%March 20, 2025 | aaii.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All HeadlinesNavitas Soars on NVIDIA Deal: Breaking Down Its Tech and OutlookBy Leo Miller | May 27, 2025View Navitas Soars on NVIDIA Deal: Breaking Down Its Tech and OutlookNVIDIA’s NVLink Fusion Ups the Ante for AI InfrastructureBy Thomas Hughes | May 19, 2025View NVIDIA’s NVLink Fusion Ups the Ante for AI InfrastructureToyota Supercharges Joby: $250M Capital Infusion Ignites Stock By Jeffrey Neal Johnson | May 28, 2025View Toyota Supercharges Joby: $250M Capital Infusion Ignites Stock Can Shopify Stock Make a Comeback After an Earnings Sell-Off?By Gabriel Osorio-Mazilli | May 12, 2025View Can Shopify Stock Make a Comeback After an Earnings Sell-Off?Rockwell Automation: Tailwinds From Onshoring U.S. ProductionBy Thomas Hughes | May 8, 2025View Rockwell Automation: Tailwinds From Onshoring U.S. ProductionKPTI, ACTU, LYEL, and GLSI Company DescriptionsActuate Therapeutics NASDAQ:ACTU$11.36 +0.79 (+7.47%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$11.88 +0.52 (+4.58%) As of 05/30/2025 07:21 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing therapies for the treatment of cancers. The company's lead product candidate is Elraglusib Injection, a novel glycogen synthase kinase-3 inhibitor to treat metastatic pancreatic ductal adenocarcinoma. It also develops Elraglusib for the treatment of Ewing sarcoma, metastatic melanoma, and colorectal cancer. The company was formerly known as Apotheca Therapeutics, Inc. and changed its name to Actuate Therapeutics, Inc. in October 2015. The company was incorporated in 2015 and is based in Fort Worth, Texas.Greenwich LifeSciences NASDAQ:GLSI$9.81 -0.11 (-1.11%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$9.94 +0.13 (+1.27%) As of 05/30/2025 07:27 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Greenwich LifeSciences, Inc., a clinical-stage biopharmaceutical company, develops novel cancer immunotherapies for breast cancer and other HER2/neu-expressing cancers. Its lead product candidate is GP2, an immunotherapy, which is in Phase III clinical trial to prevent breast cancer recurrences in patients who have previously undergone surgery. The company was formerly known as Norwell, Inc. and changed its name to Greenwich LifeSciences, Inc. in March 2018. Greenwich LifeSciences, Inc. was incorporated in 2006 and is headquartered in Stafford, Texas.Karyopharm Therapeutics NASDAQ:KPTI$4.30 -0.23 (-5.08%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$4.24 -0.06 (-1.49%) As of 05/30/2025 06:54 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. The company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, it has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.Lyell Immunopharma NASDAQ:LYEL$0.41 +0.01 (+1.92%) Closing price 05/30/2025 04:00 PM EasternExtended Trading$0.43 +0.02 (+4.57%) As of 05/30/2025 07:43 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops T cell reprogramming technologies for patients with solid tumors. The company develops therapies using an ex vivo genetic reprogramming technologies, such as c Jun overexpression and NR4A3 gene knockout, to endow resistance to T cell exhaustion; and an ex vivo epigenetic reprogramming technologies, including Epi R to generate population of T cells with durable stemness, and Stim R, a proprietary synthetic cell mimetic. It is also developing LYL797, a genetically and epigenetically reprogrammed ROR1 chimeric antigen receptor (CAR) T cell product candidate that is in Phase 1 clinical trial for the treatment of various solid tumors; and LYL845, a novel epigenetically reprogrammed tumor-infiltrating lymphocytes product candidate, which is in Phase 1 clinical trial targeting multiple solid tumor indications. In addition, the company's preclinical product candidates include LYL119, a ROR1 CAR T-cell product for the treatment of enhanced cytotoxicity; and second generation TIL product. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California. 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