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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:KRYS NASDAQ:LENZ NASDAQ:PCVX NASDAQ:PTCT On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeKRYSKrystal Biotech$137.46-2.7%$146.85$122.80▼$207.84$3.98B0.66327,357 shs322,344 shsLENZLENZ Therapeutics$41.71+4.6%$35.34$16.53▼$42.77$1.19B0.45308,549 shs428,107 shsPCVXVaxcyte$32.00-2.2%$33.21$27.66▼$121.06$4.15B1.041.76 million shs2.28 million shsPTCTPTC Therapeutics$58.33-0.2%$49.60$30.98▼$59.00$4.63B0.531.10 million shs917,296 shsA Guide To High-Short-Interest StocksMarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceKRYSKrystal Biotech-2.75%-5.23%+1.84%+1.14%-24.76%LENZLENZ Therapeutics+0.66%+1.63%+15.02%+32.97%+64.90%PCVXVaxcyte+0.96%+3.68%+9.43%-7.67%-71.62%PTCTPTC Therapeutics+2.58%+11.42%+28.74%+14.95%+85.93%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeKRYSKrystal Biotech$137.46-2.7%$146.85$122.80▼$207.84$3.98B0.66327,357 shs322,344 shsLENZLENZ Therapeutics$41.71+4.6%$35.34$16.53▼$42.77$1.19B0.45308,549 shs428,107 shsPCVXVaxcyte$32.00-2.2%$33.21$27.66▼$121.06$4.15B1.041.76 million shs2.28 million shsPTCTPTC Therapeutics$58.33-0.2%$49.60$30.98▼$59.00$4.63B0.531.10 million shs917,296 shsA Guide To High-Short-Interest StocksMarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceKRYSKrystal Biotech-2.75%-5.23%+1.84%+1.14%-24.76%LENZLENZ Therapeutics+0.66%+1.63%+15.02%+32.97%+64.90%PCVXVaxcyte+0.96%+3.68%+9.43%-7.67%-71.62%PTCTPTC Therapeutics+2.58%+11.42%+28.74%+14.95%+85.93%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceKRYSKrystal Biotech 2.88Moderate Buy$210.3853.04% UpsideLENZLENZ Therapeutics 3.00Buy$49.6018.92% UpsidePCVXVaxcyte 3.14Buy$121.75280.47% UpsidePTCTPTC Therapeutics 2.53Moderate Buy$69.0018.29% UpsideCurrent Analyst Ratings BreakdownLatest LENZ, PTCT, KRYS, and PCVX Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails9/3/2025PTCTPTC TherapeuticsCantor FitzgeraldSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOverweight$118.008/22/2025KRYSKrystal BiotechChardan CapitalSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$219.00 ➝ $216.008/22/2025KRYSKrystal BiotechHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$240.008/20/2025PTCTPTC TherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOverweight$79.00 ➝ $73.008/20/2025PTCTPTC TherapeuticsMorgan StanleySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOverweight$76.00 ➝ $71.008/20/2025PTCTPTC TherapeuticsBank of AmericaSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$82.00 ➝ $76.008/8/2025PTCTPTC TherapeuticsRobert W. BairdSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingSet Price Target$70.008/8/2025PTCTPTC TherapeuticsCowenSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingHold8/8/2025PTCTPTC TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOutperform$60.00 ➝ $63.008/8/2025PTCTPTC TherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOverweight$78.00 ➝ $79.008/7/2025PCVXVaxcyteCowenSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy(Data available from 9/10/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookKRYSKrystal Biotech$359.21M11.08$4.39 per share31.31$32.90 per share4.18LENZLENZ TherapeuticsN/AN/AN/AN/A$7.42 per shareN/APCVXVaxcyteN/AN/AN/AN/A$26.52 per shareN/APTCTPTC Therapeutics$806.78M5.74N/AN/A($14.24) per share-4.10Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateKRYSKrystal Biotech$89.16M$4.9227.9413.64N/A40.85%15.21%13.81%11/3/2025 (Estimated)LENZLENZ Therapeutics-$49.77M-$1.90N/AN/AN/AN/A-25.63%-24.43%11/5/2025 (Estimated)PCVXVaxcyte-$463.93M-$4.11N/AN/AN/AN/A-16.85%-15.92%11/4/2025 (Estimated)PTCTPTC Therapeutics-$363.30M$6.978.37N/AN/A35.65%-106.31%30.61%11/6/2025 (Estimated)Latest LENZ, PTCT, KRYS, and PCVX EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025PTCTPTC Therapeutics-$1.07-$0.83+$0.24-$0.83$173.01 million$178.88 million8/6/2025Q2 2025PCVXVaxcyte-$1.12-$1.22-$0.10-$1.22N/AN/A8/4/2025Q2 2025KRYSKrystal Biotech$1.08$1.29+$0.21$1.29$95.42 million$96.04 million7/30/2025Q2 2025LENZLENZ Therapeutics-$0.58-$0.53+$0.05-$0.53$5.00 million$5.00 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthKRYSKrystal BiotechN/AN/AN/AN/AN/ALENZLENZ TherapeuticsN/AN/AN/AN/AN/APCVXVaxcyteN/AN/AN/AN/AN/APTCTPTC TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioKRYSKrystal BiotechN/A9.689.33LENZLENZ TherapeuticsN/A20.5420.54PCVXVaxcyteN/A11.1111.11PTCTPTC TherapeuticsN/A3.623.57Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipKRYSKrystal Biotech86.29%LENZLENZ Therapeutics54.32%PCVXVaxcyte96.78%PTCTPTC TherapeuticsN/AInsider OwnershipCompanyInsider OwnershipKRYSKrystal Biotech13.70%LENZLENZ Therapeutics6.90%PCVXVaxcyte3.10%PTCTPTC Therapeutics5.50%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableKRYSKrystal Biotech21028.94 million24.98 millionOptionableLENZLENZ Therapeutics11028.52 million26.55 millionN/APCVXVaxcyte160129.82 million125.80 millionOptionablePTCTPTC Therapeutics1,41079.44 million75.07 millionOptionableLENZ, PTCT, KRYS, and PCVX HeadlinesRecent News About These CompaniesInsider Selling: PTC Therapeutics (NASDAQ:PTCT) Insider Sells 39,850 Shares of StockSeptember 10 at 6:00 AM | insidertrades.comAQR Capital Management LLC Boosts Stake in PTC Therapeutics, Inc. $PTCTSeptember 10 at 3:53 AM | marketbeat.comCantor Fitzgerald Keeps Their Buy Rating on PTC Therapeutics (PTCT)September 8 at 10:21 PM | theglobeandmail.comPTC Therapeutics, Inc. (PTCT) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference (Transcript)September 8 at 1:09 PM | seekingalpha.comPTC Therapeutics, Inc. $PTCT Shares Bought by Parkman Healthcare Partners LLCSeptember 8 at 7:45 AM | marketbeat.comPTC Therapeutics, Inc. (NASDAQ:PTCT) Receives $69.00 Consensus Price Target from AnalystsSeptember 8 at 2:51 AM | americanbankingnews.comPTC Therapeutics, Inc. (PTCT) Presents At Cantor Global Healthcare Conference 2025 TranscriptSeptember 7 at 11:01 PM | seekingalpha.comPTC Therapeutics, Inc. (PTCT) Presents At Wells Fargo 20th Annual Healthcare Conference 2025 TranscriptSeptember 7 at 10:00 PM | seekingalpha.comAdage Capital Partners GP L.L.C. Increases Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 7 at 5:13 AM | marketbeat.comPTC Therapeutics, Inc. (NASDAQ:PTCT) Receives Average Rating of "Moderate Buy" from AnalystsSeptember 7 at 3:09 AM | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Receives "Overweight" Rating from Cantor FitzgeraldSeptember 5, 2025 | marketbeat.comPDT Partners LLC Has $2.06 Million Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 5, 2025 | marketbeat.comCanada Pension Plan Investment Board Purchases 138,800 Shares of PTC Therapeutics, Inc. $PTCTSeptember 5, 2025 | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Director Sells $83,600.05 in StockSeptember 4, 2025 | marketbeat.comPTC Therapeutics (NASDAQ:PTCT) Stock Price Up 6.1% - Should You Buy?September 4, 2025 | marketbeat.comMPM Bioimpact LLC Has $22.42 Million Holdings in PTC Therapeutics, Inc. $PTCTSeptember 4, 2025 | marketbeat.comPalo Alto Investors LP Grows Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 4, 2025 | marketbeat.comPTC Therapeutics Sees RS Rating Improve To 77September 3, 2025 | msn.comIeq Capital LLC Grows Stock Position in PTC Therapeutics, Inc. $PTCTSeptember 3, 2025 | marketbeat.comPTC Therapeutics, Inc. $PTCT Stock Holdings Decreased by Armistice Capital LLCSeptember 2, 2025 | marketbeat.comTrexquant Investment LP Lowers Position in PTC Therapeutics, Inc. $PTCTSeptember 1, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeLENZ, PTCT, KRYS, and PCVX Company DescriptionsKrystal Biotech NASDAQ:KRYS$137.46 -3.75 (-2.66%) Closing price 04:00 PM EasternExtended Trading$137.49 +0.03 (+0.02%) As of 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, and commercializes genetic medicines for patients with rare diseases in the United States. It commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). The company also develops KB105, which is in Phase 1/2 clinical trials for treating patients with deficient autosomal recessive congenital ichthyosis; KB104 for treating netherton syndrome; KB407 that is in Phase 1 clinical trials for treating cystic fibrosis; KB707 that is in Phase 1 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.LENZ Therapeutics NASDAQ:LENZ$41.71 +1.82 (+4.56%) Closing price 04:00 PM EasternExtended Trading$42.38 +0.67 (+1.61%) As of 06:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.LENZ Therapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing therapies to improve vision in the United States. Its product candidates include LNZ100 and LNZ101 which are in Phase III clinical trials for the treatment of presbyopia. The company is headquartered in Del Mar, California.Vaxcyte NASDAQ:PCVX$32.00 -0.72 (-2.20%) Closing price 04:00 PM EasternExtended Trading$32.53 +0.53 (+1.66%) As of 05:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.PTC Therapeutics NASDAQ:PTCT$58.33 -0.09 (-0.15%) Closing price 04:00 PM EasternExtended Trading$58.32 -0.01 (-0.02%) As of 04:26 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders in the United States and internationally. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy; Upstaza to treat aromatic l-amino acid decarboxylas (AADC) deficiency, a central nervous system disorder; Tegsedi and Waylivra for the treatment of rare diseases; and Evrysdi to treat spinal muscular atrophy (SMA) in adults and children. Its development pipeline products include Sepiapterin for the treatment of phenylketonuria; PTC518 splicing platform, which is being developed for the treatment of Huntington's disease; and ferroptosis and inflammation platforms, including vatiquinone to treat Friedreich ataxia and utreloxastat for the treatment of amyotrophic lateral sclerosis. The company distributes its products through third-party distributors. It has collaborations with F. Hoffman-La Roche Ltd, Hoffman-La Roche Inc., the SMA Foundation, National Taiwan University, Akcea Therapeutics, Inc., and Shiratori Pharmaceutical Co., Ltd. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey. 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