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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
HALO Halozyme Therapeutics	$53.15 +0.1%	$56.88	$42.01 ▼ $70.51	$6.55B	1.19	1.64 million shs	1.40 million shs
LGND Ligand Pharmaceuticals	$114.64 +1.9%	$106.50	$77.53 ▼ $129.90	$2.21B	0.83	116,852 shs	144,654 shs
MDGL Madrigal Pharmaceuticals	$282.72 +1.1%	$295.64	$200.63 ▼ $377.46	$6.28B	-1.08	361,084 shs	303,304 shs
RGEN Repligen	$117.54 -2.9%	$128.79	$102.97 ▼ $182.52	$6.60B	1.1	738,146 shs	1.45 million shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
HALO Halozyme Therapeutics	0.00%	-2.55%	-0.56%	-18.43%	+5.73%
LGND Ligand Pharmaceuticals	0.00%	+0.17%	+9.26%	+6.00%	+42.34%
MDGL Madrigal Pharmaceuticals	0.00%	-4.88%	-3.43%	-17.24%	+2.43%
RGEN Repligen	0.00%	-10.48%	-7.88%	-16.05%	-4.44%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
HALO Halozyme Therapeutics	4.8771 of 5 stars	3.1	2.0	4.4	3.0	2.5	4.4
LGND Ligand Pharmaceuticals	4.4194 of 5 stars	3.5	0.0	4.4	2.5	3.3	1.9
MDGL Madrigal Pharmaceuticals	4.1837 of 5 stars	3.4	1.0	4.6	2.4	3.3	0.6
RGEN Repligen	4.6601 of 5 stars	4.3	1.0	4.5	2.9	1.7	1.9

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
HALO Halozyme Therapeutics	2.17	Hold	$61.90	16.46% Upside
LGND Ligand Pharmaceuticals	3.00	Buy	$146.14	27.48% Upside
MDGL Madrigal Pharmaceuticals	2.89	Moderate Buy	$420.63	48.78% Upside
RGEN Repligen	2.69	Moderate Buy	$173.25	47.40% Upside

Current Analyst Ratings Breakdown

Latest LGND, HALO, MDGL, and RGEN Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
5/29/2025	HALO Halozyme Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$72.00
5/14/2025	HALO Halozyme Therapeutics	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Overweight ➝ Equal Weight	$73.00 ➝ $62.00
5/13/2025	HALO Halozyme Therapeutics	Leerink Partnrs Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Hold ➝ Strong Sell
5/13/2025	HALO Halozyme Therapeutics	Leerink Partners Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Market Perform ➝ Underperform	$47.00
5/9/2025	LGND Ligand Pharmaceuticals	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$142.00 ➝ $145.00
5/7/2025	HALO Halozyme Therapeutics	Benchmark Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Strong-Buy ➝ Hold
5/7/2025	HALO Halozyme Therapeutics	Wells Fargo & Company Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Equal Weight ➝ Equal Weight	$60.00 ➝ $65.00
5/5/2025	RGEN Repligen	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$180.00 ➝ $180.00
5/2/2025	MDGL Madrigal Pharmaceuticals	UBS Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$441.00 ➝ $458.00
5/2/2025	MDGL Madrigal Pharmaceuticals	B. Riley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$422.00 ➝ $460.00
5/2/2025	MDGL Madrigal Pharmaceuticals	Canaccord Genuity Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$394.00 ➝ $420.00

(Data available from 6/20/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
HALO Halozyme Therapeutics	$1.02B	6.45	$4.65 per share	11.42	$2.86 per share	18.58
LGND Ligand Pharmaceuticals	$167.13M	13.23	$1.61 per share	71.35	$43.95 per share	2.61
MDGL Madrigal Pharmaceuticals	$180.13M	34.84	N/A	N/A	$34.59 per share	8.17
RGEN Repligen	$634.44M	10.41	$3.11 per share	37.83	$35.21 per share	3.34

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
HALO Halozyme Therapeutics	$444.09M	$3.76	14.14	8.55	0.35	44.76%	136.91%	26.05%	8/5/2025 (Estimated)
LGND Ligand Pharmaceuticals	-$4.03M	-$7.12	N/A	30.90	N/A	-73.07%	-7.83%	-6.92%	8/5/2025 (Estimated)
MDGL Madrigal Pharmaceuticals	-$465.89M	-$18.05	N/A	N/A	N/A	-123.38%	-50.54%	-37.19%	8/6/2025 (Estimated)
RGEN Repligen	-$25.51M	-$0.45	N/A	49.81	3.37	-3.93%	4.53%	3.17%	7/29/2025 (Estimated)

Latest LGND, HALO, MDGL, and RGEN Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
5/8/2025	Q1 2025	LGND Ligand Pharmaceuticals	$1.23	$1.33	+$0.10	-$2.21	$37.84 million	$45.33 million
5/6/2025	Q1 2025	HALO Halozyme Therapeutics	$0.98	$1.11	+$0.13	$0.93	$231.21 million	$264.86 million
5/1/2025	Q1 2025	MDGL Madrigal Pharmaceuticals	-$3.62	-$3.32	+$0.30	-$3.32	$112.79 million	$137.25 million
4/29/2025	Q1 2025	RGEN Repligen	$0.35	$0.39	+$0.04	$0.10	$163.65 million	$169.17 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
HALO Halozyme Therapeutics	N/A	N/A	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
MDGL Madrigal Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
RGEN Repligen	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
HALO Halozyme Therapeutics	3.13	8.39	7.30
LGND Ligand Pharmaceuticals	N/A	5.27	5.02
MDGL Madrigal Pharmaceuticals	0.17	5.91	5.58
RGEN Repligen	0.27	6.79	5.79

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
HALO Halozyme Therapeutics	97.79%
LGND Ligand Pharmaceuticals	91.28%
MDGL Madrigal Pharmaceuticals	98.50%
RGEN Repligen	97.64%

Insider Ownership

Company	Insider Ownership
HALO Halozyme Therapeutics	2.40%
LGND Ligand Pharmaceuticals	7.00%
MDGL Madrigal Pharmaceuticals	21.50%
RGEN Repligen	1.20%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
HALO Halozyme Therapeutics	390	123.22 million	120.26 million	Optionable
LGND Ligand Pharmaceuticals	80	19.29 million	17.94 million	Optionable
MDGL Madrigal Pharmaceuticals	90	22.20 million	17.43 million	Optionable
RGEN Repligen	1,778	56.18 million	55.51 million	Optionable

LGND, HALO, MDGL, and RGEN Headlines

Recent News About These Companies

Conestoga Capital Advisors LLC Purchases 32,665 Shares of Repligen Co. (NASDAQ:RGEN)

June 17 at 5:20 AM | marketbeat.com

Trust Point Inc. Trims Holdings in Repligen Co. (NASDAQ:RGEN)

June 17 at 4:17 AM | marketbeat.com

Repligen (NASDAQ:RGEN) Shares Down 3.1% - Should You Sell?

June 16, 2025 | marketbeat.com

Azzad Asset Management Inc. ADV Acquires Shares of 21,077 Repligen Co. (NASDAQ:RGEN)

June 15, 2025 | marketbeat.com

Repligen Co. (NASDAQ:RGEN) Receives $173.25 Average PT from Analysts

June 14, 2025 | americanbankingnews.com

Does Repligen Corp (RGEN) Have a Strong Pricing Power?

June 13, 2025 | insidermonkey.com

Repligen Co. (NASDAQ:RGEN) Receives Consensus Rating of "Moderate Buy" from Analysts

June 11, 2025 | marketbeat.com

Repligen: Long-Term Growth Gem Suffers Some Setbacks

June 8, 2025 | seekingalpha.com

Congress Asset Management Co. Grows Holdings in Repligen Co. (NASDAQ:RGEN)

June 8, 2025 | marketbeat.com

NBC Securities Inc. Purchases 2,672 Shares of Repligen Co. (NASDAQ:RGEN)

June 7, 2025 | marketbeat.com

GAMMA Investing LLC Has $15.51 Million Stock Position in Repligen Co. (NASDAQ:RGEN)

June 7, 2025 | marketbeat.com

Drug Development Inputs & Services Stocks Q1 In Review: Repligen (NASDAQ:RGEN) Vs Peers

June 5, 2025 | finance.yahoo.com

Craig-Hallum Sticks to Its Buy Rating for Repligen (RGEN)

June 5, 2025 | theglobeandmail.com

Winners And Losers Of Q1: Repligen (NASDAQ:RGEN) Vs The Rest Of The Drug Development Inputs & Services Stocks

June 5, 2025 | msn.com

Harbor Investment Advisory LLC Has $373,000 Stake in Repligen Co. (NASDAQ:RGEN)

June 4, 2025 | marketbeat.com

Repligen at William Blair Conference: Innovation Drives Growth

June 3, 2025 | investing.com

Repligen Co. (NASDAQ:RGEN) Stock Holdings Cut by Squarepoint Ops LLC

May 30, 2025 | marketbeat.com

Why Is Repligen (RGEN) Down 12.2% Since Last Earnings Report?

May 29, 2025 | zacks.com

Repligen Co. (NASDAQ:RGEN) Position Raised by Polar Asset Management Partners Inc.

May 29, 2025 | marketbeat.com

Tidal Investments LLC Decreases Position in Repligen Co. (NASDAQ:RGEN)

May 29, 2025 | marketbeat.com

UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Has $33.88 Million Stock Position in Repligen Co. (NASDAQ:RGEN)

May 28, 2025 | marketbeat.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

LGND, HALO, MDGL, and RGEN Company Descriptions

Halozyme Therapeutics NASDAQ:HALO

$53.15 +0.04 (+0.08%)

Closing price 06/18/2025 04:00 PM Eastern

Extended Trading

$53.16 +0.01 (+0.01%)

As of 06/18/2025 07:18 PM Eastern

Halozyme Therapeutics, Inc., a biopharma technology platform company, researches, develops, and commercializes proprietary enzymes and devices in the United States, Switzerland, Belgium, Japan, and internationally. The company's products are based on the patented recombinant human hyaluronidase enzyme (rHuPH20) that enables delivery of injectable biologics, such as monoclonal antibodies and other therapeutic molecules, as well as small molecules and fluids. It offers Hylenex recombinant, a formulation of rHuPH20 to facilitate subcutaneous (SC) fluid administration for achieving hydration to enhance the dispersion and absorption of other injected drugs in SC urography and to enhance resorption of radiopaque agents; rilpivirine, cabotegravir, and N6LS BNAB for the treatment of HIV; ocrelizumab for multiple sclerosis; XYOSTED, an injection for SC administration of testosterone replacement therapy; and ATRS-1902, a proprietary drug device combination product. The company also provides Herceptin (trastuzumab), Herceptin Hylecta, and Phesgo to treat breast cancer; Mabthera SC for the treatment of chronic lymphocytic leukemia; HYQVIA to treat primary immunodeficiency disorders; and DARZALEX for patients with amyloidosis, smoldering myeloma, and multiple myeloma. In addition, it offers Epinephrine Injection to treat allergic reactions; nivolumab+relatlimab and ANTI-TIM3 for the treatment of solid tumors; ARGX-117 for multifocal motor neuropathy; atezolizumab; nivolumab; afgartigimod; teriparatide injections; and OTREXUP, a SC methotrexate injection for adults with severe active rheumatoid arthritis and severe recalcitrant psoriasis, as well as children with active polyarticular juvenile idiopathic arthritis. Further, the company provides ATRS-1902 for adrenal crisis rescue; ARGX-113; and ARGX-117 to treat severe autoimmune diseases in multifocal motor neuropathy. Halozyme Therapeutics, Inc. was founded in 1998 and is headquartered in San Diego, California.

Ligand Pharmaceuticals NASDAQ:LGND

$114.64 +2.10 (+1.87%)

Closing price 06/18/2025 04:00 PM Eastern

Extended Trading

$114.47 -0.17 (-0.15%)

As of 06/18/2025 06:07 PM Eastern

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; Filspari, a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for immunoglobulin A nephropathy; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by streptococcus pneumoniae serotypes; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and children aged 8 years and older with Stage 2 T1D; Nexterone, a captisol-enabled formulation of amiodarone; Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression; and Veklury, an antiviral treatment for moderate or severe COVID-19. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of post-menopausal symptoms in women; Exemptia for autoimmune diseases; Vivitra for breast cancer; and Bryxta and Zybev for various indications. The company has alliances, licenses, and other business relationships with Amgen, Merck, Pfizer, Jazz, Takeda, Gilead Sciences, and Baxter International. Further, it sells Captisol materials. Ligand Pharmaceuticals Incorporated was incorporated in 1987 and is based in Jupiter, Florida.

Madrigal Pharmaceuticals NASDAQ:MDGL

$282.72 +3.12 (+1.12%)

Closing price 06/18/2025 04:00 PM Eastern

Extended Trading

$284.75 +2.03 (+0.72%)

As of 06/18/2025 07:26 PM Eastern

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutics for the treatment of non-alcoholic steatohepatitis (NASH) in the United States. Its lead product candidate is resmetirom, a liver-directed thyroid hormone receptor beta agonist, which is in Phase 3 clinical trials for treating NASH. The company is headquartered in West Conshohocken, Pennsylvania.

Repligen NASDAQ:RGEN

$117.54 -3.47 (-2.87%)

Closing price 06/18/2025 04:00 PM Eastern

Extended Trading

$145.50 +27.96 (+23.79%)

As of 06/18/2025 04:51 PM Eastern

Repligen Corporation develops and commercializes bioprocessing technologies and systems for use in biological drug manufacturing process in North America, Europe, the Asia Pacific, and internationally. It offers Protein A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company's chromatography products include OPUS pre-packed chromatography columns, which are used in the purification of biologics; and OPUS smaller-scale columns that are used in the high throughput process development screening, viral clearance validation studies, and scale down validation of chromatography processes. It also offers ELISA test kits; and chromatography resins under the CaptivA brand. In addition, the company provides filtration products, such as XCell Alternating Tangential Flow systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration, buffer exchange, and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; Spectra/Por laboratory and process dialysis products, and ProConnex TFDF flow paths. Further, it provides process analytics products, such as slope spectroscopy systems under the SoloVPE, FlowVPE, and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has collaboration agreements with Navigo Proteins GmbH to develop multiple affinity ligands. The company was incorporated in 1981 and is headquartered in Waltham, Massachusetts.

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Comparative Price Performance Over Time