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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ALKSNASDAQ:FOLDNASDAQ:IONSNASDAQ:MNKD On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeALKSAlkermes$31.78+3.9%$31.33$22.90▼$36.45$5.24B0.391.77 million shs3.46 million shsFOLDAmicus Therapeutics$6.67-0.1%$7.95$6.20▼$12.65$2.05B0.792.69 million shs6.37 million shsIONSIonis Pharmaceuticals$32.78+3.4%$30.56$23.95▼$52.34$5.21B0.291.55 million shs1.89 million shsMNKDMannKind$5.00+1.0%$4.94$4.17▼$7.63$1.50B1.142.39 million shs1.64 million shsReduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Enter your email address to learn more about using beta to protect your portfolio.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceALKSAlkermes+3.92%+14.15%-2.66%+0.79%+32.36%FOLDAmicus Therapeutics-0.15%-9.25%-16.52%-30.38%-36.05%IONSIonis Pharmaceuticals+3.37%+10.37%+14.18%+2.76%-23.79%MNKDMannKind+1.01%+5.49%-0.40%-13.64%+15.21%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationALKSAlkermes4.1783 of 5 stars3.31.00.04.22.02.51.9FOLDAmicus Therapeutics4.2457 of 5 stars3.42.00.04.33.00.81.9IONSIonis Pharmaceuticals4.3994 of 5 stars4.31.00.03.03.43.30.6MNKDMannKind3.148 of 5 stars3.62.00.00.03.60.81.9Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceALKSAlkermes 2.67Moderate Buy$38.3320.62% UpsideFOLDAmicus Therapeutics 2.70Moderate Buy$16.22143.21% UpsideIONSIonis Pharmaceuticals 2.65Moderate Buy$56.6772.87% UpsideMNKDMannKind 3.22Buy$9.5691.25% UpsideCurrent Analyst Ratings BreakdownLatest MNKD, IONS, ALKS, and FOLD Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/2/2025ALKSAlkermesRoyal Bank of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetSector Perform ➝ Sector Perform$39.00 ➝ $40.005/2/2025ALKSAlkermesRobert W. BairdSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$38.00 ➝ $41.005/2/2025FOLDAmicus TherapeuticsUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$21.00 ➝ $22.005/2/2025FOLDAmicus TherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$12.00 ➝ $9.005/1/2025IONSIonis PharmaceuticalsGuggenheimSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$65.00 ➝ $64.005/1/2025IONSIonis PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$45.00 ➝ $50.004/30/2025IONSIonis PharmaceuticalsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$60.00 ➝ $55.004/28/2025ALKSAlkermesRoyal Bank of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingUnderperform ➝ Underperform4/28/2025ALKSAlkermesUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingSector Perform ➝ Sector Perform4/28/2025ALKSAlkermesUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$38.00 ➝ $33.004/15/2025IONSIonis PharmaceuticalsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$60.00 ➝ $60.00(Data available from 5/3/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookALKSAlkermes$1.56B3.36$2.39 per share13.32$9.05 per share3.51FOLDAmicus Therapeutics$528.30M3.89N/AN/A$0.63 per share10.59IONSIonis Pharmaceuticals$705.14M7.39N/AN/A$3.70 per share8.86MNKDMannKind$285.50M5.32N/AN/A($0.91) per share-5.49Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateALKSAlkermes$367.07M$2.1714.6523.202.2023.57%30.80%19.09%N/AFOLDAmicus Therapeutics-$151.58M-$0.18N/A15.511.51-10.62%12.44%2.60%N/AIONSIonis Pharmaceuticals-$366.29M-$2.99N/AN/AN/A-64.25%-100.05%-15.70%N/AMNKDMannKind-$11.94M$0.1071.4321.74N/A8.07%-17.74%8.68%5/8/2025 (Estimated)Latest MNKD, IONS, ALKS, and FOLD EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/8/2025Q1 2025MNKDMannKind$0.03N/AN/AN/A$75.86 millionN/A5/1/2025Q1 2025ALKSAlkermes$0.32$0.13-$0.19$0.13$307.53 million$306.51 million4/30/2025Q1 2025IONSIonis Pharmaceuticals-$1.07-$0.93+$0.14-$0.93$144.31 million$132.00 million2/26/2025Q4 2024MNKDMannKind$0.03$0.03N/A$0.03$74.99 million$76.78 million2/19/2025Q4 2024IONSIonis Pharmaceuticals-$1.12-$0.66+$0.46-$0.66$140.97 million$227.00 million2/12/2025Q4 2024ALKSAlkermes$0.81$0.92+$0.11$0.88$379.74 millionN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthALKSAlkermesN/AN/AN/AN/AN/AFOLDAmicus TherapeuticsN/AN/AN/AN/AN/AIONSIonis PharmaceuticalsN/AN/AN/AN/AN/AMNKDMannKindN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioALKSAlkermesN/A3.042.65FOLDAmicus Therapeutics2.013.392.42IONSIonis Pharmaceuticals2.128.478.82MNKDMannKindN/A4.544.17Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipALKSAlkermes95.21%FOLDAmicus TherapeuticsN/AIONSIonis Pharmaceuticals93.86%MNKDMannKind49.55%Insider OwnershipCompanyInsider OwnershipALKSAlkermes4.40%FOLDAmicus Therapeutics2.20%IONSIonis Pharmaceuticals2.71%MNKDMannKind2.70%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableALKSAlkermes2,280164.84 million154.66 millionOptionableFOLDAmicus Therapeutics480307.92 million292.23 millionOptionableIONSIonis Pharmaceuticals800158.97 million153.62 millionOptionableMNKDMannKind400303.85 million267.51 millionOptionableMNKD, IONS, ALKS, and FOLD HeadlinesRecent News About These CompaniesApollo Management Holdings L.P. Sells 300,000 Shares of MannKind Co. (NASDAQ:MNKD)May 2 at 8:08 AM | marketbeat.comMannKind Corporation to Hold 2025 First Quarter Financial Results Conference Call on May 8, 2025May 1 at 4:17 PM | globenewswire.comRaymond James Financial Inc. Takes Position in MannKind Co. (NASDAQ:MNKD)April 29, 2025 | marketbeat.comMannKind Co. (NASDAQ:MNKD) Shares Sold by Nitorum Capital L.P.April 28, 2025 | marketbeat.comOberweis Asset Management Inc. Has $6.23 Million Stock Holdings in MannKind Co. (NASDAQ:MNKD)April 27, 2025 | marketbeat.comMariner LLC Buys New Stake in MannKind Co. (NASDAQ:MNKD)April 27, 2025 | marketbeat.comInvesco Ltd. Lowers Stock Position in MannKind Co. (NASDAQ:MNKD)April 27, 2025 | marketbeat.comMarshall Wace LLP Buys 214,873 Shares of MannKind Co. (NASDAQ:MNKD)April 26, 2025 | marketbeat.comWalleye Capital LLC Lowers Stock Holdings in MannKind Co. (NASDAQ:MNKD)April 26, 2025 | marketbeat.comEversept Partners LP Has $5.86 Million Position in MannKind Co. (NASDAQ:MNKD)April 24, 2025 | marketbeat.comRenaissance Technologies LLC Acquires 330,100 Shares of MannKind Co. (NASDAQ:MNKD)April 21, 2025 | marketbeat.comWells Fargo & Company MN Sells 209,520 Shares of MannKind Co. (NASDAQ:MNKD)April 21, 2025 | marketbeat.comRussell Investments Group Ltd. Sells 190,563 Shares of MannKind Co. (NASDAQ:MNKD)April 20, 2025 | marketbeat.comMizuho Upgrades MannKind (NASDAQ:MNKD) to Strong-BuyApril 13, 2025 | marketbeat.comMannKind Co. (NASDAQ:MNKD) Shares Purchased by Vanguard Group Inc.April 12, 2025 | marketbeat.comMannKind Co. (NASDAQ:MNKD) Receives Consensus Rating of "Buy" from BrokeragesApril 12, 2025 | marketbeat.comMannKind (NASDAQ:MNKD) Shares Gap Down - Should You Sell?April 10, 2025 | marketbeat.comMannKind initiated with an Outperform at MizuhoApril 10, 2025 | markets.businessinsider.comMizuho starts MannKind with Outperform on positive Tyvaso checksApril 10, 2025 | markets.businessinsider.comExodusPoint Capital Management LP Has $2.86 Million Stake in MannKind Co. (NASDAQ:MNKD)April 9, 2025 | marketbeat.comPrudential Financial Inc. Lowers Position in MannKind Co. (NASDAQ:MNKD)April 9, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All Headlines2 Defensive Sectors to Protect Your Portfolio During a RecessionBy Ryan Hasson | April 7, 2025View 2 Defensive Sectors to Protect Your Portfolio During a RecessionTime to Buy Alibaba and PDD After Tariff Exemptions?By Gabriel Osorio-Mazilli | April 17, 2025View Time to Buy Alibaba and PDD After Tariff Exemptions?Why Institutions Are Buying Super Micro Computer Stock AgainBy Gabriel Osorio-Mazilli | April 28, 2025View Why Institutions Are Buying Super Micro Computer Stock AgainAT&T, Verizon & T-Mobile: Who Won the Big 3 Telecom Battle in Q1?By Leo Miller | May 1, 2025View AT&T, Verizon & T-Mobile: Who Won the Big 3 Telecom Battle in Q1?United States Steel's Crash: An Unmissable Buying OpportunityBy Gabriel Osorio-Mazilli | April 11, 2025View United States Steel's Crash: An Unmissable Buying OpportunityMNKD, IONS, ALKS, and FOLD Company DescriptionsAlkermes NASDAQ:ALKS$31.78 +1.20 (+3.92%) Closing price 05/2/2025 04:00 PM EasternExtended Trading$31.44 -0.34 (-1.05%) As of 05/2/2025 05:11 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Alkermes plc, a biopharmaceutical company, researches, develops, and commercializes pharmaceutical products to address unmet medical needs of patients in therapeutic areas in the United States, Ireland, and internationally. It has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder and a pipeline of clinical and preclinical product candidates in development for neurological disorders. Its marketed products include ARISTADA, an intramuscular injectable suspension for the treatment of schizophrenia; ARISTADA INITIO for the treatment of schizophrenia in adults; VIVITROL for the treatment of alcohol and prevention of opioid dependence; and LYBALVI, an oral atypical antipsychotic drug candidate for the treatment of adults with schizophrenia and bipolar I disorder. It has collaboration agreements primarily with Janssen Pharmaceutica N.V., Janssen Pharmaceutica Inc, and Janssen Pharmaceutica International. The company also offers proprietary technology platforms to third parties to enable them to develop, commercialize, and manufacture products. Alkermes plc was founded in 1987 and is headquartered in Dublin, Ireland.Amicus Therapeutics NASDAQ:FOLD$6.67 -0.01 (-0.15%) Closing price 05/2/2025 04:00 PM EasternExtended Trading$6.63 -0.04 (-0.54%) As of 05/2/2025 07:25 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant; and Pombiliti + Opfolda, for the treatment of late onset. It has collaboration and license agreements with the University of Pennsylvania to research and develop parvovirus gene therapy products; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Princeton, New Jersey.Ionis Pharmaceuticals NASDAQ:IONS$32.78 +1.07 (+3.37%) Closing price 05/2/2025 04:00 PM EasternExtended Trading$33.06 +0.28 (+0.87%) As of 05/2/2025 07:14 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.MannKind NASDAQ:MNKD$5.00 +0.05 (+1.01%) Closing price 05/2/2025 04:00 PM EasternExtended Trading$4.97 -0.03 (-0.50%) As of 05/2/2025 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.MannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of inhaled therapeutic products for endocrine and orphan lung diseases in the United States. It offers Afrezza, an inhaled insulin used to improve glycemic control in adults with diabetes, and the V-Go wearable insulin delivery device, which provides continuous subcutaneous infusion of insulin in adults. The company's product pipeline also includes Tyvaso DPI (Treprostinil), an inhalation powder for the treatment of pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease; MNKD-101, a nebulized formulation of clofazimine, for the treatment of severe chronic and recurrent pulmonary infections, including nontuberculous mycobacterial lung disease; MNKD-201, a dry-powder formulation of nintedanib, for the treatment of idiopathic pulmonary fibrosis (IPF). In addition, it has collaboration and license agreement with United Therapeutics Corporation for development, regulatory, and commercial activities of Tyvaso DPI; co-promotion agreement with Vertice Pharma to promote Thyquidity; and collaboration agreement with Thirona to evaluate the therapeutic for the treatment of pulmonary fibrosis. Further, the company has supply and distribution agreement with Biomm S.A. for the commercialization of Afrezza in Brazil; and license and distribution agreement with Cipla Ltd. for the marketing and distribution of Afrezza in India. MannKind Corporation was incorporated in 1991 and is headquartered in Danbury, Connecticut. 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