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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
$17.14
+3.1%
$16.77
$8.72
$27.41
$617.70M1.23278,615 shs229,861 shs
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
$4.31
+5.6%
$3.99
$1.01
$5.78
$674.18M0.22.19 million shs2.33 million shs
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
$3.99
+2.3%
$4.23
$2.23
$5.38
$157.54M0.29121,250 shs216,704 shs
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
$6.47
$6.47
$5.73
$8.75
$644.66M0.79N/AN/A
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
+1.22%+1.22%+8.62%-16.73%+19.64%
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
-5.56%-4.23%+2.51%+13.97%+274.31%
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-0.76%-6.02%-7.58%+23.42%+62.50%
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
0.00%0.00%0.00%0.00%0.00%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
$17.14
+3.1%
$16.77
$8.72
$27.41
$617.70M1.23278,615 shs229,861 shs
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
$4.31
+5.6%
$3.99
$1.01
$5.78
$674.18M0.22.19 million shs2.33 million shs
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
$3.99
+2.3%
$4.23
$2.23
$5.38
$157.54M0.29121,250 shs216,704 shs
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
$6.47
$6.47
$5.73
$8.75
$644.66M0.79N/AN/A
The 7 Hottest IPO Stories of 2026 Cover

MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.

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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
+1.22%+1.22%+8.62%-16.73%+19.64%
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
-5.56%-4.23%+2.51%+13.97%+274.31%
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-0.76%-6.02%-7.58%+23.42%+62.50%
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
0.00%0.00%0.00%0.00%0.00%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
2.60
Moderate Buy$29.4071.53% Upside
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
2.57
Moderate Buy$6.2344.62% Upside
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
2.25
Hold$17.50338.60% Upside
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
0.00
N/AN/AN/A

Current Analyst Ratings Breakdown

Latest OKUR, IRWD, SVA, and CBIO Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
8/14/2026
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
Reiterated RatingOutperform$14.00
8/7/2026
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
Reiterated RatingSell (D-)
8/7/2026
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
UpgradeSell (D+)Hold (C-)
7/30/2026
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
DowngradeStrong-BuyHold
7/28/2026
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
DowngradeSell (D-)Sell (E+)
7/24/2026
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
Reiterated RatingSell (D+)
7/20/2026
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
Lower Price TargetBuy$21.00
7/16/2026
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
Reiterated RatingNeutral
7/1/2026
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
UpgradeHoldStrong-Buy
5/29/2026
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
UpgradeSell (E+)Sell (D-)
(Data available from 8/14/2023 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
$10.84M58.73N/AN/A$4.29 per share4.00
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
$296.15M2.40$0.27 per share15.85($0.98) per share-4.40
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/AN/AN/AN/A$4.26 per shareN/A
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
$386.01M1.67$0.54 per share11.89$89.01 per share0.07
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
-$153.94M-$6.72N/AN/AN/AN/A-101.50%-86.86%N/A
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
$24.02M$0.775.60N/AN/A33.36%-58.38%34.93%N/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-$59.52M-$3.50N/AN/AN/AN/A-49.01%-45.77%N/A
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
-$59.68MN/AN/AN/AN/AN/AN/AN/AN/A

Latest OKUR, IRWD, SVA, and CBIO Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/6/2026Q2 2026
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
$0.32$0.31-$0.01$0.31$114.84 million$113.04 million
8/4/2026Q2 2026
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-$0.5350-$0.31+$0.2250-$0.31$0.17 millionN/A
7/30/2026Q2 2026
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
-$0.7357-$0.74-$0.0043-$0.74$0.36 millionN/A
CompanyAnnual PayoutDividend Yield5-Year Annualized Dividend GrowthPayout RatioYears of Consecutive Growth
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
N/AN/AN/AN/AN/A
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
N/AN/AN/AN/AN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/AN/AN/AN/AN/A
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
N/A
9.66
9.66
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
N/A
6.06
1.41
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/A
26.75
26.75
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
0.04
4.59
4.53

Institutional Ownership

CompanyInstitutional Ownership
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
75.19%
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
N/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
90.98%
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
N/A

Insider Ownership

CompanyInsider Ownership
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
24.84%
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
9.30%
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
2.17%
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
12.79%
CompanyEmployeesShares OutstandingFree FloatOptionable
Crescent Biopharma, Inc. stock logo
CBIO
Crescent Biopharma
5037.14 million27.92 millionNo Data
Ironwood Pharmaceuticals, Inc. stock logo
IRWD
Ironwood Pharmaceuticals
220165.24 million147.89 millionOptionable
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/A40.40 million39.52 millionN/A
Sinovac Biotech, Ltd. stock logo
SVA
Sinovac Biotech
3,00899.64 million86.89 millionOptionable

Recent News About These Companies

Reviewing Sinovac Biotech (NASDAQ:SVA) & Burning Rock Biotech (NASDAQ:BNR)
Sinovac Biotech Ltd.
SVA Share News Today
Sinovac Biotech Delays Key Annual 20-F Filing
Sinovac Controlling Shareholders Escape Investor Disclosure Suit

New MarketBeat Followers Over Time

Media Sentiment Over Time

Crescent Biopharma stock logo

Crescent Biopharma NASDAQ:CBIO

$17.14 +0.51 (+3.07%)
Closing price 04:00 PM Eastern
Extended Trading
$17.14 +0.00 (+0.03%)
As of 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Crescent Biopharma, Inc. operates as a biopharmaceutical company that develops and designs small molecule therapeutics to treat cancers. The company was founded on September 19, 2024 and is headquartered in Waltham, MA.

Ironwood Pharmaceuticals stock logo

Ironwood Pharmaceuticals NASDAQ:IRWD

$4.31 +0.23 (+5.64%)
Closing price 04:00 PM Eastern
Extended Trading
$4.23 -0.08 (-1.86%)
As of 07:43 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Ironwood Pharmaceuticals, Inc., a healthcare company, focuses on the development and commercialization of gastrointestinal (GI) products. It markets linaclotide, a guanylate cyclase type-C (GC-C) agonist for the treatment of adults suffering from irritable bowel syndrome with constipation or chronic idiopathic constipation under the LINZESS name in the United States, Mexico, Japan, Saudi Arabia, and China, as well as under the CONSTELLA name in the Canada and European countries. The company is also developing IW-3300, a GC-C agonist for the treatment of visceral pain conditions, including interstitial cystitis/bladder pain syndrome and endometriosis; Apraglutide, a next-generation, long-acting synthetic peptide analog of glucagon-like peptide-2, as a differentiated therapeutic for rare diseases, including short bowel syndrome dependent on parenteral support and acute graft versus host disease; and CNP-104, an immune nanoparticle for the treatment of primary biliary cholangitis. The company has strategic partnerships with AbbVie Inc., AstraZeneca AB, and Astellas Pharma Inc. for the development and commercialization of linaclotide. The company was formerly known as Microbia, Inc. and changed its name to Ironwood Pharmaceuticals, Inc. in April 2008. Ironwood Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Boston, Massachusetts.

OnKure Therapeutics stock logo

OnKure Therapeutics NASDAQ:OKUR

$3.99 +0.09 (+2.31%)
Closing price 04:00 PM Eastern
Extended Trading
$3.97 -0.02 (-0.50%)
As of 04:39 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

OnKure Therapeutics, Inc. engages in discovering and developing precision medicines that target biologically validated drivers of cancers underserved by available therapies. The company uses a structure and computational chemistry driven drug design platform, committed to improving clinical outcomes for patients by building a robust pipeline of small molecule drugs designed to selectively target specific mutations thought to be key drivers of cancer. It is headquartered in Boulder, CO.

Sinovac Biotech stock logo

Sinovac Biotech NASDAQ:SVA

$6.47 0.00 (0.00%)
As of 08/13/2026

Sinovac Biotech Ltd., a biopharmaceutical company, focuses in the research, development, manufacture, and commercialization of vaccines against human infectious diseases in the People's Republic of China. The company's product portfolio includes vaccines against hepatitis A and B; hand, foot, and mouth diseases caused by enterovirus 71 (EV71); seasonal influenza; H5N1 and H1N1 pandemic influenza; coronavirus; varicella; and mumps. Its marketed products include Healive, an inactivated hepatitis A vaccine; Bilive, a combined inactivated hepatitis A and B vaccine; Anflu, a split viron influenza vaccine; Panflu, a vaccine against the H5N1 influenza virus; Panflu.1, a vaccine against the influenza A H1N1 virus; mumps vaccine to treat viral disease in human species; split viron pandemic influenza vaccine; and Inlive, an EV71 vaccine. The company also offers varicella, a vaccine to treat contagious infectious disease; pneumococcal polysaccharide vaccine, a vaccine to prevent streptococcus pneumoniae infections, such as pneumonia and septicemia; quadrivalent influenza vaccine, a vaccine to protect against two influenza A viruses and two influenza B viruses; and CoronaVac, a vaccine against COVID-19. In addition, its pipeline products include sabin inactivated polio vaccine, a vaccine to treat Poliomyelitis that has completed phase III clinical trial; and rubella vaccine. The company has collaboration agreements with GlaxoSmithKline Biologicals SA to develop combination vaccines containing measles for the China market; Tianjin CanSino Biotechnology Inc. to develop a pneumococcal vaccine; and Instituto Butantan to advance the clinical trials of CoronaVac, an inactivated vaccine candidate against COVID-19 to Phase III. Sinovac Biotech Ltd. was founded in 1993 and is headquartered in Beijing, the People's Republic of China.