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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$144.45
+0.1%
$146.80
$122.80
$207.84
$4.18B0.66326,752 shs238,079 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$32.35
-2.1%
$33.18
$27.66
$121.06
$4.20B1.041.75 million shs973,181 shs
Pharvaris N.V. stock logo
PHVS
Pharvaris
$23.37
-0.5%
$21.79
$11.51
$26.33
$1.22B-2.884,001 shs23,694 shs
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$61.04
+0.1%
$50.03
$33.19
$62.18
$4.84B0.531.10 million shs1.21 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
+5.02%-3.60%+0.52%+5.32%-27.38%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
+3.31%+2.83%+10.20%-4.34%-70.89%
Pharvaris N.V. stock logo
PHVS
Pharvaris
+1.08%+6.92%+11.43%+40.72%+12.01%
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
+4.51%+5.09%+34.66%+18.92%+88.91%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$144.45
+0.1%
$146.80
$122.80
$207.84
$4.18B0.66326,752 shs238,079 shs
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$32.35
-2.1%
$33.18
$27.66
$121.06
$4.20B1.041.75 million shs973,181 shs
Pharvaris N.V. stock logo
PHVS
Pharvaris
$23.37
-0.5%
$21.79
$11.51
$26.33
$1.22B-2.884,001 shs23,694 shs
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$61.04
+0.1%
$50.03
$33.19
$62.18
$4.84B0.531.10 million shs1.21 million shs
A Guide To High-Short-Interest Stocks Cover

MarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
+5.02%-3.60%+0.52%+5.32%-27.38%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
+3.31%+2.83%+10.20%-4.34%-70.89%
Pharvaris N.V. stock logo
PHVS
Pharvaris
+1.08%+6.92%+11.43%+40.72%+12.01%
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
+4.51%+5.09%+34.66%+18.92%+88.91%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
2.86
Moderate Buy$209.0045.97% Upside
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
3.00
Buy$106.25229.76% Upside
Pharvaris N.V. stock logo
PHVS
Pharvaris
2.80
Moderate Buy$34.0042.68% Upside
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
2.53
Moderate Buy$69.0013.04% Upside

Current Analyst Ratings Breakdown

Latest PHVS, PTCT, KRYS, and PCVX Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
9/12/2025
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
The Goldman Sachs Group
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageNeutral$38.00
9/3/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingOverweight$118.00
8/22/2025
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
Chardan Capital
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetBuy$219.00 ➝ $216.00
8/22/2025
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy$240.00
8/20/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Wells Fargo & Company
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetOverweight$79.00 ➝ $73.00
8/20/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Morgan Stanley
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetOverweight$76.00 ➝ $71.00
8/20/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Bank of America
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetBuy$82.00 ➝ $76.00
8/18/2025
Pharvaris N.V. stock logo
PHVS
Pharvaris
Zacks Research
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UpgradeStrong SellHold
8/13/2025
Pharvaris N.V. stock logo
PHVS
Pharvaris
JMP Securities
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Lower Price TargetMarket Outperform$55.00 ➝ $52.00
8/8/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Robert W. Baird
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Set Price Target$70.00
8/8/2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
Cowen
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingHold
(Data available from 9/12/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$290.52M14.26$4.83 per share29.64$32.90 per share4.35
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/A$26.52 per shareN/A
Pharvaris N.V. stock logo
PHVS
Pharvaris
N/AN/AN/AN/A$5.54 per shareN/A
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$806.78M6.01N/AN/A($14.24) per share-4.29
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$89.16M$4.9229.1014.20N/A40.85%15.21%13.81%11/3/2025 (Estimated)
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$463.93M-$4.11N/AN/AN/AN/A-16.85%-15.92%11/4/2025 (Estimated)
Pharvaris N.V. stock logo
PHVS
Pharvaris
-$145.24M-$3.36N/AN/AN/AN/A-69.09%-63.34%11/12/2025 (Estimated)
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
-$363.30M$6.978.75N/AN/A35.65%-106.31%30.61%11/6/2025 (Estimated)

Latest PHVS, PTCT, KRYS, and PCVX Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/12/2025Q2 2025
Pharvaris N.V. stock logo
PHVS
Pharvaris
-$0.87-$0.94-$0.07-$0.94N/AN/A
8/7/2025Q2 2025
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
-$1.07-$0.83+$0.24-$0.83$173.01 million$178.88 million
8/6/2025Q2 2025
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
-$1.12-$1.22-$0.10-$1.22N/AN/A
8/4/2025Q2 2025
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$1.08$1.29+$0.21$1.29$95.42 million$96.04 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
N/AN/AN/AN/AN/A
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/AN/AN/AN/AN/A
Pharvaris N.V. stock logo
PHVS
Pharvaris
N/AN/AN/AN/AN/A
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
N/A
9.68
9.33
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
N/A
11.11
11.11
Pharvaris N.V. stock logo
PHVS
Pharvaris
N/A
8.33
8.33
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
N/A
3.62
3.57

Institutional Ownership

CompanyInstitutional Ownership
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
86.29%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
96.78%
Pharvaris N.V. stock logo
PHVS
Pharvaris
N/A
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
N/A

Insider Ownership

CompanyInsider Ownership
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
13.70%
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
3.10%
Pharvaris N.V. stock logo
PHVS
Pharvaris
11.84%
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
5.50%
CompanyEmployeesShares OutstandingFree FloatOptionable
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
21028.94 million24.98 millionOptionable
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
160129.82 million125.80 millionOptionable
Pharvaris N.V. stock logo
PHVS
Pharvaris
3052.29 million46.10 millionNot Optionable
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
1,41079.44 million75.07 millionOptionable

Recent News About These Companies

PTC Therapeutics (NASDAQ:PTCT) Director Sells $700,080.00 in Stock
PTC Therapeutics, Inc. (PTCT) Launches SUFIANCE for PKU

New MarketBeat Followers Over Time

Media Sentiment Over Time

Krystal Biotech stock logo

Krystal Biotech NASDAQ:KRYS

$144.62 +0.26 (+0.18%)
As of 03:44 PM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, and commercializes genetic medicines for patients with rare diseases in the United States. It commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). The company also develops KB105, which is in Phase 1/2 clinical trials for treating patients with deficient autosomal recessive congenital ichthyosis; KB104 for treating netherton syndrome; KB407 that is in Phase 1 clinical trials for treating cystic fibrosis; KB707 that is in Phase 1 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.

Vaxcyte stock logo

Vaxcyte NASDAQ:PCVX

$32.44 -0.62 (-1.86%)
As of 03:44 PM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine for the prevention of invasive pneumococcal disease. The company also develops VAX-31 to protect against emerging strains and to help address antibiotic resistance; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting keystone pathogen responsible for periodontitis; and VAX-GI to prevent Shigella, a bacterial illness. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.

Pharvaris stock logo

Pharvaris NASDAQ:PHVS

$23.39 -0.11 (-0.45%)
As of 03:44 PM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Pharvaris N.V., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases. The company develops PHA121, a small molecule bradykinin B2-receptor antagonist for the treatment of hereditary angioedema (HAE). It also develops PHVS416, an on-demand, rapid exposure soft capsule for patients suffering from acute HAE attacks which is under Phase 2 clinical trial; and PHVS719, a prophylactic extended-release tablet for HAE patients which is under Phase 1 clinical trial. The company operates in the Netherlands, Switzerland, and the United States. Pharvaris N.V. was incorporated in 2015 and is based in Leiden, the Netherlands.

PTC Therapeutics stock logo

PTC Therapeutics NASDAQ:PTCT

$61.04 +0.08 (+0.13%)
As of 03:44 PM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

PTC Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines to patients with rare disorders in the United States and internationally. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy; Upstaza to treat aromatic l-amino acid decarboxylas (AADC) deficiency, a central nervous system disorder; Tegsedi and Waylivra for the treatment of rare diseases; and Evrysdi to treat spinal muscular atrophy (SMA) in adults and children. Its development pipeline products include Sepiapterin for the treatment of phenylketonuria; PTC518 splicing platform, which is being developed for the treatment of Huntington's disease; and ferroptosis and inflammation platforms, including vatiquinone to treat Friedreich ataxia and utreloxastat for the treatment of amyotrophic lateral sclerosis. The company distributes its products through third-party distributors. It has collaborations with F. Hoffman-La Roche Ltd, Hoffman-La Roche Inc., the SMA Foundation, National Taiwan University, Akcea Therapeutics, Inc., and Shiratori Pharmaceutical Co., Ltd. PTC Therapeutics, Inc. was incorporated in 1998 and is headquartered in South Plainfield, New Jersey.