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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:APGE NASDAQ:DYN NASDAQ:IMCR NASDAQ:PRTA On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAPGEApogee Therapeutics$36.05-1.0%$39.91$26.20▼$63.50$1.66B1.43740,884 shs239,069 shsDYNDyne Therapeutics$11.96-2.3%$10.37$6.36▼$47.39$1.70B1.082.63 million shs1.15 million shsIMCRImmunocore$32.55+0.6%$33.45$23.15▼$39.33$1.64B0.77337,334 shs437,921 shsPRTAProthena$8.520.0%$6.62$4.32▼$22.83$458.47M-0.031.06 million shs510,737 shsReduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Enter your email address to learn more about using beta to protect your portfolio.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAPGEApogee Therapeutics-1.33%-0.79%-7.38%-9.38%-27.24%DYNDyne Therapeutics-0.65%+5.42%+35.81%+4.17%-73.44%IMCRImmunocore+0.09%+1.47%-10.93%+2.15%-12.33%PRTAProthena-0.12%+13.00%+36.10%+24.93%-59.79%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAPGEApogee Therapeutics3.5679 of 5 stars4.43.00.00.01.64.20.0DYNDyne Therapeutics3.2958 of 5 stars4.51.00.00.01.45.00.0IMCRImmunocore1.957 of 5 stars3.31.00.00.02.82.50.0PRTAProthena3.2716 of 5 stars4.24.00.00.01.41.70.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAPGEApogee Therapeutics 2.86Moderate Buy$99.00174.60% UpsideDYNDyne Therapeutics 3.00Buy$33.80182.51% UpsideIMCRImmunocore 2.50Moderate Buy$58.0078.19% UpsidePRTAProthena 2.33Hold$30.25255.17% UpsideCurrent Analyst Ratings BreakdownLatest PRTA, APGE, IMCR, and DYN Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/14/2025APGEApogee TherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeStrong-Buy ➝ Hold8/11/2025APGEApogee TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$90.008/6/2025DYNDyne TherapeuticsOppenheimerSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$34.00 ➝ $13.008/5/2025PRTAProthenaRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetSector Perform ➝ Sector Perform$18.00 ➝ $10.008/5/2025PRTAProthenaHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$14.008/5/2025PRTAProthenaChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$18.007/31/2025DYNDyne TherapeuticsStifel NicolausSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$66.00 ➝ $36.007/29/2025DYNDyne TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$25.00 ➝ $23.007/29/2025DYNDyne TherapeuticsRaymond James FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$37.00 ➝ $31.007/29/2025DYNDyne TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$50.00 ➝ $38.007/15/2025DYNDyne TherapeuticsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$10.00 ➝ $9.00(Data available from 8/20/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAPGEApogee TherapeuticsN/AN/AN/AN/A$13.43 per shareN/ADYNDyne TherapeuticsN/AN/AN/AN/A$4.02 per shareN/AIMCRImmunocore$356.15M4.61N/AN/A$7.71 per share4.22PRTAProthena$135.16M3.39N/AN/A$6.03 per share1.41Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAPGEApogee Therapeutics-$182.15M-$4.13N/AN/AN/AN/A-34.65%-32.76%N/ADYNDyne Therapeutics-$317.42M-$3.86N/AN/AN/AN/A-64.12%-56.75%N/AIMCRImmunocore-$51.09M-$0.40N/AN/AN/A-5.70%-5.40%-1.93%11/5/2025 (Estimated)PRTAProthena-$122.31M-$5.64N/AN/AN/A-2,929.30%-62.17%-54.43%N/ALatest PRTA, APGE, IMCR, and DYN EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/11/2025Q2 2025APGEApogee Therapeutics-$1.03-$1.13-$0.10-$1.13N/AN/A8/7/2025Q2 2025IMCRImmunocore-$0.21-$0.20+$0.01-$0.20$122.96 million$130.65 million8/4/2025Q2 2025PRTAProthena-$1.11-$1.86-$0.75-$2.34$5.36 million$4.42 million7/28/2025Q2 2025DYNDyne Therapeutics-$0.99-$0.97+$0.02-$0.97N/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAPGEApogee TherapeuticsN/AN/AN/AN/AN/ADYNDyne TherapeuticsN/AN/AN/AN/AN/AIMCRImmunocoreN/AN/AN/AN/AN/APRTAProthenaN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAPGEApogee TherapeuticsN/A16.3616.36DYNDyne Therapeutics0.1716.8316.83IMCRImmunocore1.015.895.86PRTAProthenaN/A5.685.68Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAPGEApogee Therapeutics79.04%DYNDyne Therapeutics96.68%IMCRImmunocore84.50%PRTAProthena97.08%Insider OwnershipCompanyInsider OwnershipAPGEApogee Therapeutics42.77%DYNDyne Therapeutics20.77%IMCRImmunocore10.40%PRTAProthena9.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAPGEApogee Therapeutics9146.11 million26.39 millionOptionableDYNDyne Therapeutics100142.26 million112.72 millionOptionableIMCRImmunocore32050.39 million45.15 millionOptionablePRTAProthena13053.83 million48.88 millionOptionablePRTA, APGE, IMCR, and DYN HeadlinesRecent News About These CompaniesAnalysts Set Prothena Corporation plc (NASDAQ:PRTA) Price Target at $30.25August 17 at 2:17 AM | americanbankingnews.comProthena Corporation plc (NASDAQ:PRTA) Receives Consensus Recommendation of "Hold" from AnalystsAugust 15, 2025 | marketbeat.comProthena (NASDAQ:PRTA) Stock Price Passes Below Two Hundred Day Moving Average - Should You Sell?August 14, 2025 | marketbeat.comCitizens JMP Remains a Buy on Prothena (PRTA)August 9, 2025 | theglobeandmail.comFY2026 EPS Estimates for Prothena Lifted by Chardan CapitalAugust 9, 2025 | marketbeat.comCantor Fitzgerald Increases Earnings Estimates for ProthenaAugust 8, 2025 | marketbeat.comFY2025 EPS Estimates for Prothena Reduced by HC WainwrightAugust 8, 2025 | marketbeat.comNovo Nordisk Commits To Advancing Prothena Corp-Developed Drug Into Late Stage Trial: Retail Turns HopefulAugust 7, 2025 | msn.comProthena (NASDAQ:PRTA) Price Target Cut to $10.00 by Analysts at Royal Bank Of CanadaAugust 6, 2025 | marketbeat.comProthena Announces that Novo Nordisk Will Advance Coramitug (Formerly PRX004) into Phase 3 Development for ATTR Amyloidosis with CardiomyopathyAugust 6, 2025 | businesswire.comProthena's (PRTA) Buy Rating Reiterated at HC WainwrightAugust 6, 2025 | marketbeat.comProthena (NASDAQ:PRTA) Given "Buy" Rating at Chardan CapitalAugust 6, 2025 | marketbeat.comProthena (NASDAQ:PRTA) Announces Earnings Results, Misses Expectations By $0.80 EPSAugust 5, 2025 | marketbeat.com9 Analysts Assess Prothena Corp: What You Need To KnowAugust 5, 2025 | benzinga.comProthena Reports Q2 2025 Financial Results and Pipeline ProgressAugust 4, 2025 | tipranks.comProthena (PRTA) Reports Q2 Loss, Lags Revenue EstimatesAugust 4, 2025 | zacks.comProthena Reports Second Quarter 2025 Financial Results and Business HighlightsAugust 4, 2025 | businesswire.comProthena Corporation plc (NASDAQ:PRTA) Shares Purchased by DCF Advisers LLCAugust 4, 2025 | marketbeat.comFederated Hermes Inc. Sells 199,922 Shares of Prothena Corporation plc (NASDAQ:PRTA)August 3, 2025 | marketbeat.comA Glimpse of Prothena Corp's Earnings PotentialAugust 2, 2025 | benzinga.comProthena Secures Leadership with New Executive AgreementsJuly 31, 2025 | msn.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimePRTA, APGE, IMCR, and DYN Company DescriptionsApogee Therapeutics NASDAQ:APGE$36.05 -0.36 (-0.98%) Closing price 03:59 PM EasternExtended Trading$36.03 -0.02 (-0.06%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), asthma, chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indications. The company primarily develops APG777, a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for AD; and APG808, an SQ extended half-life mAb for COPD. Its earlier-stage programs comprise APG990, an SQ extended half-life mAb for the treatment of AD; and APG222, an extended half-life SQ antibodies for AD. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.Dyne Therapeutics NASDAQ:DYN$11.96 -0.29 (-2.33%) Closing price 03:59 PM EasternExtended Trading$12.16 +0.20 (+1.64%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Dyne Therapeutics, Inc., a clinical-stage muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. Dyne Therapeutics, Inc. was incorporated in 2017 and is headquartered in Waltham, Massachusetts.Immunocore NASDAQ:IMCR$32.55 +0.21 (+0.65%) Closing price 03:59 PM EasternExtended Trading$32.47 -0.08 (-0.25%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Immunocore Holdings plc, a commercial-stage biotechnology company, engages in the development of immunotherapies for the treatment of cancer, infectious, and autoimmune diseases. The company offers KIMMTRAK for the treatment of patients with unresectable or metastatic uveal melanoma. It also develops other programs for oncology, including tebentafusp that is in Phase 2/3 clinical trial to treat advanced cutaneous melanoma. In addition, the company's product pipeline comprises IMC-F106C, which is in a Phase 3 clinical trial to treat first line advanced cutaneous melanoma; and in a Phase 1/2 clinical trial in multiple tumor types, such as platinum resistant ovarian, non-small cell lung, and endometrial carcinoma. Further, it develops IMC-R117C, which is in phase 1 clinical trial to treat colorectal and gastrointestinal cancers; IMC-M113V, which is in phase 1 clinical trial to treat human immunosuppression virus; IMC-I109V, which is in a Phase I clinical trial in patients with chronic hepatitis B virus; IMC-T119C, which is in preclinical trial for multiple solid tumor cancers; IMC-P115C, which is in preclinical trial to treat multiple solid tumor cancers; and IMC-S118AI to treat type 1 diabetes and is in preclinical trial. Immunocore Holdings plc was founded in 1999 and is headquartered in Abingdon, the United Kingdom.Prothena NASDAQ:PRTA$8.52 0.00 (-0.04%) Closing price 03:59 PM EasternExtended Trading$8.48 -0.04 (-0.43%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation in the United States. The company is involved in developing birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, for the treatment of Parkinson's disease and other related synucleinopathies which is in Phase IIb clinical trial; NNC6019 that is in Phase lI clinical trial for the treatment of ATTR amyloidosis; and BMS-986446 and PRX012, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX123, a dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease; and PRX019 for the treatment of neurogenerative diseases, as well as TDP-43 for the treatment of amyotrophic lateral sclerosis. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and a collaboration agreement with Bristol-Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. The company was incorporated in 2012 and is based in Dublin, Ireland. 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