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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
CureVac stock logo
CVAC
CureVac
$4.09
-1.7%
$3.22
$2.37
$5.28
$917.54M2.43763,962 shs755,856 shs
Pharvaris stock logo
PHVS
Pharvaris
$15.99
-2.4%
$15.39
$11.51
$25.50
$836.12M-2.8572,739 shs16,327 shs
Acelyrin, Inc. stock logo
SLRN
Acelyrin
$2.27
$2.37
$1.85
$7.25
$229.17M1.071.24 million shsN/A
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$15.01
-0.4%
$14.65
$10.91
$40.26
$904.74M2.78611,682 shs210,288 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
CureVac stock logo
CVAC
CureVac
+6.67%+21.64%+30.41%+26.06%+6.39%
Pharvaris stock logo
PHVS
Pharvaris
-0.06%+3.02%+8.61%-0.61%-17.93%
Acelyrin, Inc. stock logo
SLRN
Acelyrin
-0.35%+4.61%-2.99%-12.69%-49.78%
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
+1.96%+3.65%+7.95%-29.22%-57.61%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
CureVac stock logo
CVAC
CureVac
3.57 of 5 stars
3.51.00.04.81.70.01.3
Pharvaris stock logo
PHVS
Pharvaris
1.2631 of 5 stars
3.51.00.00.01.90.80.0
Acelyrin, Inc. stock logo
SLRN
Acelyrin
3.4982 of 5 stars
3.24.00.00.03.43.31.3
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
2.3312 of 5 stars
3.60.00.00.03.72.50.6
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
CureVac stock logo
CVAC
CureVac
3.00
Buy$14.00242.30% Upside
Pharvaris stock logo
PHVS
Pharvaris
3.00
Buy$40.67154.33% Upside
Acelyrin, Inc. stock logo
SLRN
Acelyrin
2.40
Hold$9.60322.91% Upside
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
3.25
Buy$53.40255.76% Upside

Current Analyst Ratings Breakdown

Latest SLRN, SYRE, PHVS, and CVAC Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/14/2025
Pharvaris stock logo
PHVS
Pharvaris
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetOverweight ➝ Overweight$28.00 ➝ $25.00
5/5/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform$65.00
4/30/2025
CureVac stock logo
CVAC
CureVac
UBS Group
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$13.00 ➝ $12.00
4/29/2025
Pharvaris stock logo
PHVS
Pharvaris
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight$28.00
4/8/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeStrong-Buy
4/8/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Leerink Partners
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$45.00
3/18/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Wolfe Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$27.00
(Data available from 5/23/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
CureVac stock logo
CVAC
CureVac
$535.18M1.71N/AN/A$2.50 per share1.64
Pharvaris stock logo
PHVS
Pharvaris
N/AN/AN/AN/A$7.95 per shareN/A
Acelyrin, Inc. stock logo
SLRN
Acelyrin
N/AN/AN/AN/A$6.74 per shareN/A
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$890K1,016.56N/AN/A($0.22) per share-68.23
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
CureVac stock logo
CVAC
CureVac
-$281.58M$0.827.44N/AN/A20.72%21.98%15.72%N/A
Pharvaris stock logo
PHVS
Pharvaris
-$109.18M-$3.01N/AN/AN/AN/A-38.52%-36.69%N/A
Acelyrin, Inc. stock logo
SLRN
Acelyrin
-$381.64M-$2.69N/AN/AN/AN/A-44.12%-39.02%N/A
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
-$338.79M-$3.77N/AN/AN/AN/A-210.01%-44.40%8/6/2025 (Estimated)

Latest SLRN, SYRE, PHVS, and CVAC Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/22/2025Q1 2025
CureVac stock logo
CVAC
CureVac
-$0.16-$0.24-$0.08-$0.24$4.27 million$0.94 million
5/14/2025Q1 2025
Acelyrin, Inc. stock logo
SLRN
Acelyrin
-$0.95-$0.55+$0.40-$0.55N/AN/A
5/13/2025Q1 2025
Pharvaris stock logo
PHVS
Pharvaris
-$0.80-$0.89-$0.09-$0.89N/AN/A
5/8/2025Q1 2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
-$0.76-$0.74+$0.02-$0.74N/AN/A
4/10/2025Q4 2024
CureVac stock logo
CVAC
CureVac
-$0.14-$0.15-$0.01-$0.15$6.40 million$15.44 million
4/7/2025Q4 2024
Pharvaris stock logo
PHVS
Pharvaris
-$0.74-$0.68+$0.06-$0.68N/AN/A
3/19/2025Q4 2024
Acelyrin, Inc. stock logo
SLRN
Acelyrin
-$0.86-$0.79+$0.07-$0.79N/AN/A
2/27/2025Q4 2024
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
-$0.89-$0.81+$0.08-$0.81$2.10 millionN/A
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
CureVac stock logo
CVAC
CureVac
N/AN/AN/AN/AN/A
Pharvaris stock logo
PHVS
Pharvaris
N/AN/AN/AN/AN/A
Acelyrin, Inc. stock logo
SLRN
Acelyrin
N/AN/AN/AN/AN/A
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
CureVac stock logo
CVAC
CureVac
0.05
6.20
6.19
Pharvaris stock logo
PHVS
Pharvaris
N/A
19.08
19.08
Acelyrin, Inc. stock logo
SLRN
Acelyrin
N/A
7.15
7.15
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
N/A
7.32
7.32

Institutional Ownership

CompanyInstitutional Ownership
CureVac stock logo
CVAC
CureVac
17.26%
Pharvaris stock logo
PHVS
Pharvaris
N/A
Acelyrin, Inc. stock logo
SLRN
Acelyrin
87.31%
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
80.39%

Insider Ownership

CompanyInsider Ownership
CureVac stock logo
CVAC
CureVac
2.15%
Pharvaris stock logo
PHVS
Pharvaris
11.84%
Acelyrin, Inc. stock logo
SLRN
Acelyrin
13.60%
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
15.43%
CompanyEmployeesShares OutstandingFree FloatOptionable
CureVac stock logo
CVAC
CureVac
880224.34 million219.07 millionOptionable
Pharvaris stock logo
PHVS
Pharvaris
3052.29 million46.10 millionNot Optionable
Acelyrin, Inc. stock logo
SLRN
Acelyrin
135100.95 million86.68 millionOptionable
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
7360.28 million48.24 millionOptionable

Recent News About These Companies

New MarketBeat Followers Over Time

Media Sentiment Over Time

CureVac stock logo

CureVac NASDAQ:CVAC

$4.09 -0.07 (-1.68%)
Closing price 04:00 PM Eastern
Extended Trading
$4.15 +0.06 (+1.56%)
As of 06:00 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

CureVac N.V., a biopharmaceutical company, focuses on developing various transformative medicines based on messenger ribonucleic acid (mRNA). It is developing prophylactic vaccines, such as mRNA-based vaccine candidates CV2CoV, which is in Phase 1 clinical trial against SARS-CoV-2; CV7202 which is in Phase 1 clinical trial for the treatment of rabies; and CVSQIV to treat multivalent seasonal influenza; Flu SV mRNA fot treating nucleotides, single antigen seasonal influenza. The company develops CV8102, which is in Phase 1 clinical trial for treating melanoma and adenoidcystic carcinoma, as well as squamous cell cancer of skin, head, and neck; and CVGBM for treating cancer. CureVac N.V. was founded in 2000 and is headquartered in Tübingen, Germany.

Pharvaris stock logo

Pharvaris NASDAQ:PHVS

$15.88 -0.51 (-3.12%)
As of 04:00 PM Eastern
This is a fair market value price provided by Polygon.io. Learn more.

Pharvaris N.V., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases. The company develops PHA121, a small molecule bradykinin B2-receptor antagonist for the treatment of hereditary angioedema (HAE). It also develops PHVS416, an on-demand, rapid exposure soft capsule for patients suffering from acute HAE attacks which is under Phase 2 clinical trial; and PHVS719, a prophylactic extended-release tablet for HAE patients which is under Phase 1 clinical trial. The company operates in the Netherlands, Switzerland, and the United States. Pharvaris N.V. was incorporated in 2015 and is based in Leiden, the Netherlands.

Acelyrin stock logo

Acelyrin NASDAQ:SLRN

$2.27 0.00 (0.00%)
As of 05/21/2025

Acelyrin, Inc., a clinical biopharma company, focuses on identifying, acquiring, and accelerating the development and commercialization of transformative medicines. The company's lead product candidate is izokibep, a small protein therapeutic designed to inhibit IL-17A with high potency, which is in Phase 3 clinical trials for use in the treatment of Hidradenitis Suppurativa, Psoriatic Arthritis, and uveitis, as well as in Phase 2 clinical trials for use in the treatment of Axial Spondyloarthritis. It is also developing lonigutamab, a humanized immunoglobulin G1 (IgG1) monoclonal antibody which is in Phase 1 clinical trials for use in the treatment of thyroid eye disease. In addition, the company's develops SLRN-517, a fully human IgG1 monoclonal antibody targeting c-KIT, which is in preclinical stage for use in the treatment of chronic urticaria. Acelyrin, Inc. was incorporated in 2020 and is headquartered in Agoura Hills, California.

Spyre Therapeutics stock logo

Spyre Therapeutics NASDAQ:SYRE

$15.01 -0.06 (-0.40%)
Closing price 04:00 PM Eastern
Extended Trading
$15.01 0.00 (0.00%)
As of 04:20 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.