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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
EGRX Eagle Pharmaceuticals	$3.74 +5.4%	$2.35	$1.50 ▼ $3.87	$48.57M	0.83	8,144 shs	7,169 shs
KPTI Karyopharm Therapeutics	$4.77 +4.8%	$4.77	$3.51 ▼ $16.95	$41.21M	0.24	84,920 shs	337,474 shs
MRSN Mersana Therapeutics	$0.34 -0.3%	$0.35	$0.26 ▼ $2.83	$42.75M	0.79	2.76 million shs	1.33 million shs
TLPH Talphera	$0.47 -8.9%	$0.49	$0.38 ▼ $1.19	$9.72M	-0.11	131,014 shs	14.92 million shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
EGRX Eagle Pharmaceuticals	+5.35%	+24.67%	+55.83%	+107.78%	-37.87%
KPTI Karyopharm Therapeutics	+4.84%	+12.77%	+8.66%	+11.97%	-66.30%
MRSN Mersana Therapeutics	-0.26%	+12.72%	-6.59%	-1.58%	-83.51%
TLPH Talphera	-8.87%	+2.35%	-5.22%	-3.97%	-49.04%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
EGRX Eagle Pharmaceuticals	2.4778 of 5 stars	0.0	3.0	3.9	0.6	3.3	0.0
KPTI Karyopharm Therapeutics	4.0215 of 5 stars	3.5	0.0	4.6	2.9	2.5	0.6
MRSN Mersana Therapeutics	4.1989 of 5 stars	3.5	3.0	4.1	2.7	2.5	0.0
TLPH Talphera	2.0119 of 5 stars	3.8	2.0	0.0	3.3	0.0	0.0

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
EGRX Eagle Pharmaceuticals	0.00	N/A	N/A	N/A
KPTI Karyopharm Therapeutics	3.00	Buy	$37.40	684.07% Upside
MRSN Mersana Therapeutics	3.00	Buy	$5.20	1,416.03% Upside
TLPH Talphera	3.50	Strong Buy	$5.00	955.07% Upside

Current Analyst Ratings Breakdown

Latest TLPH, EGRX, MRSN, and KPTI Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
7/11/2025	KPTI Karyopharm Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy	$27.00
6/3/2025	MRSN Mersana Therapeutics	William Blair Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform
5/16/2025	MRSN Mersana Therapeutics	Truist Financial Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$9.00 ➝ $10.00
5/16/2025	MRSN Mersana Therapeutics	Guggenheim Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$5.00 ➝ $5.00
5/15/2025	MRSN Mersana Therapeutics	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform	$3.00
5/13/2025	KPTI Karyopharm Therapeutics	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Outperform ➝ Outperform	$34.00 ➝ $33.00
5/13/2025	KPTI Karyopharm Therapeutics	Barclays Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Overweight ➝ Overweight	$5.00 ➝ $10.00
5/13/2025	KPTI Karyopharm Therapeutics	Robert W. Baird Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Outperform ➝ Outperform	$54.00 ➝ $42.00
5/6/2025	MRSN Mersana Therapeutics	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform	$4.00 ➝ $3.00

(Data available from 7/15/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
EGRX Eagle Pharmaceuticals	$257.55M	0.19	$9.35 per share	0.40	N/A	∞
KPTI Karyopharm Therapeutics	$145.24M	0.28	N/A	N/A	($22.10) per share	-0.22
MRSN Mersana Therapeutics	$40.50M	1.06	N/A	N/A	($0.08) per share	-4.29
TLPH Talphera	$27K	359.87	N/A	N/A	$0.47 per share	1.01

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
EGRX Eagle Pharmaceuticals	$35.64M	N/A	0.00	∞	N/A	N/A	N/A	N/A	N/A
KPTI Karyopharm Therapeutics	-$76.42M	-$13.26	N/A	N/A	N/A	-43.99%	N/A	-35.95%	8/5/2025 (Estimated)
MRSN Mersana Therapeutics	-$69.19M	-$0.59	N/A	N/A	N/A	-217.63%	-990.16%	-48.87%	8/12/2025 (Estimated)
TLPH Talphera	-$13M	-$0.45	N/A	N/A	N/A	N/A	-130.28%	-59.25%	8/13/2025 (Estimated)

Latest TLPH, EGRX, MRSN, and KPTI Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/12/2025	Q2 2025	MRSN Mersana Therapeutics	-$0.18	N/A	N/A	N/A	$6.06 million	N/A
8/5/2025	Q2 2025	KPTI Karyopharm Therapeutics	-$3.72	N/A	N/A	N/A	$37.92 million	N/A
5/15/2025	Q1 2025	MRSN Mersana Therapeutics	-$0.21	-$0.19	+$0.02	-$0.19	$6.05 million	$2.75 million
5/12/2025	Q1 2025	KPTI Karyopharm Therapeutics	-$4.21	-$2.77	+$1.44	-$2.77	$35.12 million	$30.02 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
EGRX Eagle Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
KPTI Karyopharm Therapeutics	N/A	N/A	N/A	N/A	N/A
MRSN Mersana Therapeutics	N/A	N/A	N/A	N/A	N/A
TLPH Talphera	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
EGRX Eagle Pharmaceuticals	N/A	N/A	N/A
KPTI Karyopharm Therapeutics	N/A	1.33	1.28
MRSN Mersana Therapeutics	N/A	1.83	1.83
TLPH Talphera	N/A	3.11	3.11

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
EGRX Eagle Pharmaceuticals	85.36%
KPTI Karyopharm Therapeutics	66.44%
MRSN Mersana Therapeutics	93.92%
TLPH Talphera	37.67%

Insider Ownership

Company	Insider Ownership
EGRX Eagle Pharmaceuticals	28.90%
KPTI Karyopharm Therapeutics	2.75%
MRSN Mersana Therapeutics	13.00%
TLPH Talphera	3.20%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
EGRX Eagle Pharmaceuticals	100	12.99 million	9.23 million	No Data
KPTI Karyopharm Therapeutics	380	8.64 million	8.40 million	Optionable
MRSN Mersana Therapeutics	150	124.63 million	108.43 million	Optionable
TLPH Talphera	19	20.50 million	19.85 million	Optionable

TLPH, EGRX, MRSN, and KPTI Headlines

Recent News About These Companies

talphera receives extension to meet nasdaq listing requirements

June 7, 2025 | investing.com

Talphera Granted Extension for Nasdaq Compliance

June 5, 2025 | tipranks.com

Talphera, Inc.: Talphera Announces First Quarter 2025 Financial Results and Provides Corporate Update

May 17, 2025 | finanznachrichten.de

Earnings call transcript: Talphera Inc. outlines strategic shifts in Q1 2025

May 16, 2025 | uk.investing.com

Talphera, Inc. (NASDAQ:TLPH) Q1 2025 Earnings Call Transcript

May 16, 2025 | msn.com

Talphera outlines accelerated NEPHRO CRRT study timeline with completion targeted by end of 2025, supported by new site activations and $14.8M financing

May 15, 2025 | msn.com

Talphera, Inc. (TLPH) Q1 2025 Earnings Call Transcript

May 14, 2025 | seekingalpha.com

Talphera Announces First Quarter 2025 Financial Results and Provides Corporate Update

May 14, 2025 | prnewswire.com

Talphera to Host First Quarter Financial Results and Corporate Update Call and Webcast on Wednesday, May 14, 2025

May 7, 2025 | prnewswire.com

All You Need to Know About Talphera (TLPH) Rating Upgrade to Strong Buy

May 7, 2025 | msn.com

Talphera (TLPH) Upgraded to Buy: What Does It Mean for the Stock?

April 5, 2025 | msn.com

Talphera reports Q4 EPS (7c) vs. (25c) last year

April 1, 2025 | markets.businessinsider.com

Talphera, Inc. (NASDAQ:TLPH) Q4 2024 Earnings Call Transcript

April 1, 2025 | msn.com

Talphera announces agreement with FDA to reduce NEPHRO CRRT study size

April 1, 2025 | markets.businessinsider.com

Talphera Reports 2024 Financial Results and Study Update

March 31, 2025 | tipranks.com

Talphera outlines 2025 timeline for NEPHRO CRRT study completion and FDA approval of Niyad

March 31, 2025 | msn.com

Talphera, Inc. (TLPH) Q4 2024 Earnings Call Transcript

March 31, 2025 | seekingalpha.com

Talphera Announces Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update

March 31, 2025 | prnewswire.com

Talphera Announces Agreement with the FDA to Reduce the NEPHRO CRRT Study Size to 70 Patients From 166 and a Private Placement Financing Priced At-the Market of up to $14.8 Million

March 31, 2025 | prnewswire.com

7TLPH : Earnings Outlook For Talphera

March 28, 2025 | benzinga.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

TLPH, EGRX, MRSN, and KPTI Company Descriptions

Eagle Pharmaceuticals NASDAQ:EGRX

$3.74 +0.19 (+5.35%)

As of 07/14/2025 03:40 PM Eastern

Eagle Pharmaceuticals, Inc., a pharmaceutical company, focuses on developing and commercializing product candidates to treat diseases of the central nervous system or metabolic critical care, and oncology in the United States. The company offers Ryanodex for malignant hyperthermia; and Belrapzo and Bendeka for chronic lymphocytic leukemia and indolent B-cell non-Hodgkin's lymphoma. Its product candidates also include EP-4104, a dantrolene sodium to treat organophosphate exposure; PEMFEXY, a ready-to-use/dilute liquid form of pemetrexed for non-small cell lung cancer and mesothelioma; EA-114 (fulvestrant) for HR+/HER- breast cancer; and Vasopressin injection, which is indicated to enhance blood pressure in adults with vasodilatory shock. The company has license and collaboration agreements with Combioxin, SA for the development and commercialization rights to CAL02, an antitoxin agent for the treatment of severe pneumonia in combination with traditional antibacterial drugs; and AOP Orphan Pharmaceuticals GmbH for the commercial rights of Landiolol, a novel therapeutic product candidate for the short-term reduction of ventricular rate in patients with supraventricular tachycardia, including atrial fibrillation and atrial flutter. It has a strategic collaboration with Tyme Technologies, Inc. for the development of SM-88 to treat breast cancer (HR+/HER2-) and high-risk metastatic sarcomas. Eagle Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Woodcliff Lake, New Jersey.

Karyopharm Therapeutics NASDAQ:KPTI

$4.77 +0.22 (+4.84%)

Closing price 07/14/2025 04:00 PM Eastern

Extended Trading

$4.77 0.00 (0.00%)

As of 07/14/2025 07:31 PM Eastern

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. The company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, it has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Mersana Therapeutics NASDAQ:MRSN

$0.34 0.00 (-0.26%)

Closing price 07/14/2025 04:00 PM Eastern

Extended Trading

$0.34 0.00 (0.00%)

As of 07/14/2025 07:56 PM Eastern

Mersana Therapeutics, Inc., a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet needs. The company develops XMT-1660, a B7-H4-targeted Dolasynthen ADC candidate; and XMT-2056, an immunosynthen ADC. It has research and development collaborations with Janssen Biotech, Inc., Ares Trading S.A., Merck KGaA, and Asana BioSciences, LLC for the development of ADC product candidates. The company was formerly known as Nanopharma Corp. and changed its name to Mersana Therapeutics, Inc. in November 2005. Mersana Therapeutics, Inc. was incorporated in 2001 and is headquartered in Cambridge, Massachusetts.

Talphera NASDAQ:TLPH

$0.47 -0.05 (-8.87%)

Closing price 07/14/2025 04:00 PM Eastern

Extended Trading

$0.42 -0.05 (-10.95%)

As of 07/14/2025 07:59 PM Eastern

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. Its lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, an anti-inflammatory and antiviral potential for the treatment of multiple conditions, including disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis; Fedsyra, a pre-filled ephedrine syringe; and PFS-02, a pre-filled phenylephrine syringe. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is headquartered in San Mateo, California.

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Comparative Price Performance Over Time