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NASDAQ:AGIO

Agios Pharmaceuticals (AGIO) Stock Price, News & Analysis

Agios Pharmaceuticals logo
$33.10 0.00 (0.00%)
Closing price 09/4/2026 04:00 PM Eastern
Extended Trading
$33.10 0.00 (0.00%)
As of 08:48 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

About Agios Pharmaceuticals Stock (NASDAQ:AGIO)

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Key Stats

Today's Range
$32.92
$33.50
50-Day Range
$30.02
$44.01
52-Week Range
$22.24
$46.00
Volume
480,161 shs
Average Volume
896,759 shs
Market Capitalization
$1.98 billion
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$41.25
Consensus Rating
Moderate Buy

Company Overview

Agios Pharmaceuticals, Inc. is a biopharmaceutical company founded in 2008 as a spin-out from research at Dana-Farber Cancer Institute and the Broad Institute. Headquartered in Cambridge, Massachusetts, Agios focuses on understanding and targeting cellular metabolism to develop novel therapies for cancer and rare genetic diseases. The company’s scientific platform integrates genomic discovery, metabolic profiling and precision medicine approaches to identify and advance small-molecule candidates that correct or exploit metabolic dysfunction.

Agios’s lead products are IDH (isocitrate dehydrogenase) inhibitors that target specific cancer mutations. Tibsovo (ivosidenib) is approved for treating relapsed or refractory acute myeloid leukemia (AML) with an IDH1 mutation and for certain advanced cholangiocarcinoma patients. Idhifa (enasidenib) addresses AML patients bearing an IDH2 mutation. These targeted therapies represent some of the first metabolism-based oncology treatments on the market.

Beyond its approved products, Agios maintains a diverse pipeline in both oncology and rare genetic diseases. The company is developing mitapivat, a pyruvate kinase activator for chronic hemolytic anemias, in collaboration with Servier for ex-U.S. commercialization. Additional research programs leverage Agios’s expertise in metabolic targets to pursue next-generation candidates for hematologic malignancies and solid tumors. Agios markets its therapies directly in the United States and partners with global pharmaceutical companies for commercialization in Europe and other regions.

Agios went public in 2013 and has maintained its headquarters and core research operations in Cambridge. Leadership is currently headed by President and CEO Jackie Fouse, with Catherine Shacklett serving as Chief Financial Officer. The company continues to expand its scientific capabilities and strategic collaborations as it advances its mission of translating metabolism research into life-changing treatments.

AI Generated. May Contain Errors.

Agios Pharmaceuticals Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
54th Percentile Overall Score

AGIO MarketRank™: 

Agios Pharmaceuticals scored higher than 54% of companies evaluated by MarketBeat, and ranked 431st out of 906 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Agios Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.55, and is based on 1 strong buy rating, 5 buy ratings, 4 hold ratings, and 1 sell rating.

  • Upside Potential

    Agios Pharmaceuticals has a consensus price target of $41.25, representing about 24.6% upside from its current price of $33.10.

  • Amount of Analyst Coverage

    Agios Pharmaceuticals has been the subject of 8 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

  • Read more about Agios Pharmaceuticals' stock forecast and price target.
  • Earnings Growth

    Earnings for Agios Pharmaceuticals are expected to grow in the coming year, from ($5.82) to ($4.15) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Agios Pharmaceuticals is -4.72, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Agios Pharmaceuticals is -4.72, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Agios Pharmaceuticals has a P/B Ratio of 1.62. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

  • Read more about Agios Pharmaceuticals' valuation and earnings.
  • Percentage of Shares Shorted

    13.51% of the float of Agios Pharmaceuticals has been sold short.
  • Short Interest Ratio / Days to Cover

    Agios Pharmaceuticals has a short interest ratio ("days to cover") of 6.99.
  • Change versus previous month

    Short interest in Agios Pharmaceuticals has recently increased by 11.52%, indicating that investor sentiment is decreasing significantly.
  • Dividend Yield

    Agios Pharmaceuticals does not currently pay a dividend.

  • Dividend Growth

    Agios Pharmaceuticals does not have a long track record of dividend growth.

  • News Sentiment

    Agios Pharmaceuticals has a news sentiment score of 1.33. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.79 average news sentiment score of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 4 news articles for Agios Pharmaceuticals this week, compared to 9 articles on an average week.
  • Insider Buying vs. Insider Selling

    In the past three months, Agios Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $914,400.00 in company stock.

  • Percentage Held by Insiders

    5.40% of the stock of Agios Pharmaceuticals is held by insiders.

  • Percentage Held by Institutions

    Agios Pharmaceuticals has minimal institutional ownership at this time.

  • Read more about Agios Pharmaceuticals' insider trading history.
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AGIO Stock News Headlines

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AGIO Stock Analysis - Frequently Asked Questions

Agios Pharmaceuticals' stock was trading at $27.22 at the beginning of the year. Since then, AGIO shares have increased by 21.6% and is now trading at $33.10.

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) issued its earnings results on Thursday, July, 30th. The biopharmaceutical company reported ($1.69) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($1.65) by $0.04. The biopharmaceutical company earned $44.75 million during the quarter, compared to analysts' expectations of $26.40 million. Agios Pharmaceuticals had a negative trailing twelve-month return on equity of 35.67% and a negative net margin of 418.24%.
Read the conference call transcript
.

Agios Pharmaceuticals (AGIO) raised $88 million in an initial public offering on Wednesday, July 24th 2013. The company issued 5,888,888 shares at a price of $14.00-$16.00 per share.

Top institutional investors of Agios Pharmaceuticals include BlackRock Inc. (10.81%), California State Teachers Retirement System (4.15%), ADAR1 Capital Management LLC (2.16%) and Parkman Healthcare Partners LLC (1.12%). Insiders that own company stock include Jacqualyn A Fouse, Brian Goff, Cecilia Jones, Sarah Gheuens, James William Burns, Tsveta Milanova, David Scadden, Kaye I Foster-Cheek, Krishnan Viswanadhan and Theodore James Jr Washburn.
View institutional ownership trends
.

Shares of AGIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Agios Pharmaceuticals investors own include Waste Connections (WCN), American Water Works (AWK), DiamondRock Hospitality (DRH), The RMR Group (RMR), AUO (AUOTY), iShares Micro-Cap ETF (IWC) and Voyager Therapeutics (VYGR).

Company Calendar

Last Earnings
7/30/2026
Today
9/08/2026
Next Earnings (Estimated)
10/29/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:AGIO
CIK
1439222
Fax
N/A
Employees
390
Year Founded
2008

Price Target and Rating

High Price Target
$55.00
Low Price Target
$32.00
Potential Upside/Downside
+24.6%
Consensus Rating
Moderate Buy
Rating Score (0-4)
2.55
Research Coverage
11 Analysts

Profitability

EPS (Trailing Twelve Months)
($7.01)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$412.78 million
Net Margins
-418.24%
Pretax Margin
-419.27%
Return on Equity
-35.67%
Return on Assets
-33.06%

Debt

Debt-to-Equity Ratio
N/A
Current Ratio
10.22
Quick Ratio
9.79

Sales & Book Value

Annual Sales
$54.03 million
Price / Sales
36.57
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$20.46 per share
Price / Book
1.62

Miscellaneous

Outstanding Shares
59,700,000
Free Float
56,478,000
Market Cap
$1.98 billion
Optionable
Optionable
Beta
0.60

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This page (NASDAQ:AGIO) was last updated on 9/8/2026 by MarketBeat.com Staff.
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