Applied Therapeutics (APLT) Competitors $0.45 +0.03 (+8.24%) Closing price 09/18/2025 04:00 PM EasternExtended Trading$0.44 0.00 (-0.04%) As of 09/18/2025 07:42 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock APLT vs. FENC, RAPT, LYEL, IMMP, EDIT, VYGR, ACIU, VOR, SGMT, and HUMAShould you be buying Applied Therapeutics stock or one of its competitors? The main competitors of Applied Therapeutics include Adherex Technologies (FENC), Rapt Therapeutics (RAPT), Lyell Immunopharma (LYEL), Prima BioMed (IMMP), Editas Medicine (EDIT), Voyager Therapeutics (VYGR), AC Immune (ACIU), Vor Biopharma (VOR), Sagimet Biosciences (SGMT), and Humacyte (HUMA). These companies are all part of the "pharmaceutical products" industry. Applied Therapeutics vs. Its Competitors Adherex Technologies Rapt Therapeutics Lyell Immunopharma Prima BioMed Editas Medicine Voyager Therapeutics AC Immune Vor Biopharma Sagimet Biosciences Humacyte Applied Therapeutics (NASDAQ:APLT) and Adherex Technologies (NASDAQ:FENC) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, analyst recommendations, institutional ownership, dividends, earnings, risk, valuation and profitability. Is APLT or FENC more profitable? Applied Therapeutics has a net margin of 0.00% compared to Adherex Technologies' net margin of -35.05%. Adherex Technologies' return on equity of 0.00% beat Applied Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Applied TherapeuticsN/A -354.24% -144.16% Adherex Technologies -35.05%N/A -23.92% Do analysts prefer APLT or FENC? Applied Therapeutics presently has a consensus price target of $6.10, suggesting a potential upside of 1,270.17%. Adherex Technologies has a consensus price target of $13.33, suggesting a potential upside of 49.31%. Given Applied Therapeutics' higher probable upside, research analysts plainly believe Applied Therapeutics is more favorable than Adherex Technologies.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Applied Therapeutics 0 Sell rating(s) 3 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 2.50Adherex Technologies 0 Sell rating(s) 1 Hold rating(s) 3 Buy rating(s) 1 Strong Buy rating(s) 3.00 Does the media favor APLT or FENC? In the previous week, Adherex Technologies had 1 more articles in the media than Applied Therapeutics. MarketBeat recorded 2 mentions for Adherex Technologies and 1 mentions for Applied Therapeutics. Applied Therapeutics' average media sentiment score of 1.57 beat Adherex Technologies' score of 0.67 indicating that Applied Therapeutics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Applied Therapeutics 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Adherex Technologies 1 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do insiders & institutionals have more ownership in APLT or FENC? 98.3% of Applied Therapeutics shares are owned by institutional investors. Comparatively, 55.5% of Adherex Technologies shares are owned by institutional investors. 1.6% of Applied Therapeutics shares are owned by insiders. Comparatively, 11.8% of Adherex Technologies shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term. Which has more volatility and risk, APLT or FENC? Applied Therapeutics has a beta of 2.06, suggesting that its stock price is 106% more volatile than the S&P 500. Comparatively, Adherex Technologies has a beta of 0.58, suggesting that its stock price is 42% less volatile than the S&P 500. Which has higher earnings and valuation, APLT or FENC? Adherex Technologies has higher revenue and earnings than Applied Therapeutics. Adherex Technologies is trading at a lower price-to-earnings ratio than Applied Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioApplied Therapeutics$121K529.87-$105.62M-$0.45-0.99Adherex Technologies$47.54M5.24-$440K-$0.42-21.26 SummaryAdherex Technologies beats Applied Therapeutics on 9 of the 16 factors compared between the two stocks. Get Applied Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for APLT and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding APLT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart APLT vs. The Competition Export to ExcelMetricApplied TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$59.23M$3.12B$5.77B$10.28BDividend YieldN/A2.37%5.74%4.64%P/E Ratio-0.9921.2276.8626.97Price / Sales529.87472.24544.13128.91Price / CashN/A45.3237.1760.63Price / Book0.919.6913.836.37Net Income-$105.62M-$52.92M$3.29B$271.46M7 Day Performance5.85%2.19%1.57%2.53%1 Month Performance-8.02%8.96%6.86%9.42%1 Year Performance-94.44%10.84%81.58%30.16% Applied Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)APLTApplied Therapeutics4.0697 of 5 stars$0.45+8.2%$4.13+826.5%-94.3%$59.23M$121K-0.9930News CoveragePositive NewsFENCAdherex Technologies2.2606 of 5 stars$9.06+0.5%$13.33+47.2%+71.1%$252.84M$47.54M-21.5710News CoveragePositive NewsRAPTRapt Therapeutics3.6329 of 5 stars$15.10+6.8%$21.57+42.9%+40.8%$249.75M$1.53M-1.0780Gap UpLYELLyell Immunopharma2.4063 of 5 stars$12.93-1.1%$15.00+16.1%-53.2%$248.29M$60K-0.53270IMMPPrima BioMed1.3131 of 5 stars$1.67+2.5%$7.00+319.2%-24.2%$245.14M$6.69M0.002,021EDITEditas Medicine4.0004 of 5 stars$2.71+5.7%$5.10+88.4%-22.7%$243.23M$32.31M-0.95230VYGRVoyager Therapeutics3.9564 of 5 stars$4.39+5.4%$13.25+202.1%-27.9%$242.52M$80M-2.36100News CoverageAnalyst ForecastACIUAC Immune2.7167 of 5 stars$2.34-2.5%$10.00+327.4%-30.6%$234.96M$31.02M-4.03140Positive NewsVORVor Biopharma0.6935 of 5 stars$1.85+2.8%N/AN/A$234.36MN/A-0.14140Positive NewsGap UpSGMTSagimet Biosciences3.3664 of 5 stars$7.16+0.4%$25.67+258.5%+99.7%$232.84M$2M-3.918HUMAHumacyte2.8593 of 5 stars$1.47-1.0%$9.75+565.5%-66.5%$232.01M$1.57M-3.26150Gap Up Related Companies and Tools Related Companies Adherex Technologies Alternatives Rapt Therapeutics Alternatives Lyell Immunopharma Alternatives Prima BioMed Alternatives Editas Medicine Alternatives Voyager Therapeutics Alternatives AC Immune Alternatives Vor Biopharma Alternatives Sagimet Biosciences Alternatives Humacyte Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:APLT) was last updated on 9/19/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. 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