Applied Therapeutics (APLT) Competitors $0.36 -0.01 (-1.83%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock APLT vs. AVTE, SOPH, NLTX, CTMX, IPHA, BTMD, DRUG, CYBN, PRQR, and INBXShould you be buying Applied Therapeutics stock or one of its competitors? The main competitors of Applied Therapeutics include Aerovate Therapeutics (AVTE), SOPHiA GENETICS (SOPH), Neoleukin Therapeutics (NLTX), CytomX Therapeutics (CTMX), Innate Pharma (IPHA), biote (BTMD), Bright Minds Biosciences (DRUG), Cybin (CYBN), ProQR Therapeutics (PRQR), and Inhibrx (INBX). These companies are all part of the "pharmaceutical products" industry. Applied Therapeutics vs. Its Competitors Aerovate Therapeutics SOPHiA GENETICS Neoleukin Therapeutics CytomX Therapeutics Innate Pharma biote Bright Minds Biosciences Cybin ProQR Therapeutics Inhibrx Aerovate Therapeutics (NASDAQ:AVTE) and Applied Therapeutics (NASDAQ:APLT) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, earnings, valuation, dividends, community ranking, media sentiment, risk, profitability and institutional ownership. Do insiders & institutionals have more ownership in AVTE or APLT? 98.3% of Applied Therapeutics shares are held by institutional investors. 24.9% of Aerovate Therapeutics shares are held by company insiders. Comparatively, 1.6% of Applied Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term. Does the MarketBeat Community favor AVTE or APLT? Applied Therapeutics received 61 more outperform votes than Aerovate Therapeutics when rated by MarketBeat users. Likewise, 56.74% of users gave Applied Therapeutics an outperform vote while only 54.29% of users gave Aerovate Therapeutics an outperform vote. CompanyUnderperformOutperformAerovate TherapeuticsOutperform Votes1954.29% Underperform Votes1645.71% Applied TherapeuticsOutperform Votes8056.74% Underperform Votes6143.26% Does the media favor AVTE or APLT? In the previous week, Applied Therapeutics had 1 more articles in the media than Aerovate Therapeutics. MarketBeat recorded 2 mentions for Applied Therapeutics and 1 mentions for Aerovate Therapeutics. Aerovate Therapeutics' average media sentiment score of 1.61 beat Applied Therapeutics' score of 0.98 indicating that Aerovate Therapeutics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Aerovate Therapeutics 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Applied Therapeutics 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has more risk and volatility, AVTE or APLT? Aerovate Therapeutics has a beta of 0.95, indicating that its stock price is 5% less volatile than the S&P 500. Comparatively, Applied Therapeutics has a beta of 1.86, indicating that its stock price is 86% more volatile than the S&P 500. Do analysts rate AVTE or APLT? Aerovate Therapeutics currently has a consensus price target of $78.75, suggesting a potential upside of 1,020.20%. Applied Therapeutics has a consensus price target of $6.10, suggesting a potential upside of 1,571.23%. Given Applied Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Applied Therapeutics is more favorable than Aerovate Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Aerovate Therapeutics 0 Sell rating(s) 6 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 2.00Applied Therapeutics 0 Sell rating(s) 3 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 2.50 Is AVTE or APLT more profitable? Aerovate Therapeutics' return on equity of -90.19% beat Applied Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Aerovate TherapeuticsN/A -90.19% -77.47% Applied Therapeutics N/A -260.75%-76.04% Which has higher earnings and valuation, AVTE or APLT? Aerovate Therapeutics has higher earnings, but lower revenue than Applied Therapeutics. Aerovate Therapeutics is trading at a lower price-to-earnings ratio than Applied Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAerovate TherapeuticsN/AN/A-$75.52M-$1.70-4.14Applied Therapeutics$265K195.00-$119.76M-$0.43-0.85 SummaryApplied Therapeutics beats Aerovate Therapeutics on 12 of the 16 factors compared between the two stocks. Get Applied Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for APLT and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding APLT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart APLT vs. The Competition Export to ExcelMetricApplied TherapeuticsPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$51.68M$6.92B$5.61B$8.62BDividend YieldN/A2.55%5.28%4.17%P/E Ratio-0.238.6727.1419.96Price / Sales195.00262.53411.83157.63Price / CashN/A65.8538.2534.64Price / Book-1.836.597.064.69Net Income-$119.76M$143.75M$3.23B$248.14M7 Day Performance0.33%3.72%2.67%2.39%1 Month Performance-21.10%11.01%8.82%6.05%1 Year Performance-93.07%3.87%31.44%13.60% Applied Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)APLTApplied Therapeutics4.2842 of 5 stars$0.37-1.8%$6.10+1,571.2%-92.7%$51.68M$265K-0.2330AVTEAerovate Therapeutics1.8539 of 5 stars$7.21-0.6%$78.75+992.2%-99.1%$208.98MN/A-2.4120Positive NewsHigh Trading VolumeSOPHSOPHiA GENETICS1.8285 of 5 stars$3.07+2.3%$6.80+121.5%-38.1%$206.40M$67.17M-2.84520News CoverageGap DownNLTXNeoleukin TherapeuticsN/A$21.67+5.4%N/A-42.2%$203.66MN/A-6.9790High Trading VolumeCTMXCytomX Therapeutics4.3022 of 5 stars$2.47-1.8%$5.33+116.4%+89.3%$202.28M$147.56M14.76170Positive NewsIPHAInnate Pharma3.3016 of 5 stars$2.19+2.3%$11.00+402.3%-22.5%$201.87M$12.62M0.00220Positive NewsGap DownBTMDbiote3.726 of 5 stars$3.56+0.6%$8.00+124.7%-35.4%$195.04M$199.38M13.71194DRUGBright Minds Biosciences3.341 of 5 stars$27.50-0.2%$83.25+202.8%+2,469.4%$194.72MN/A-162.60N/APositive NewsAnalyst RevisionCYBNCybin3.0203 of 5 stars$8.89+3.6%$86.00+867.9%N/A$190.50MN/A-2.0250News CoverageAnalyst RevisionPRQRProQR Therapeutics3.0236 of 5 stars$1.80-0.8%$8.00+345.7%-0.5%$188.86M$18.97M-5.61180Positive NewsAnalyst RevisionINBXInhibrx3.1086 of 5 stars$13.01+0.0%N/A-12.8%$188.55M$200K0.11166Positive NewsUpcoming Earnings Related Companies and Tools Related Companies Aerovate Therapeutics Alternatives SOPHiA GENETICS Alternatives Neoleukin Therapeutics Alternatives CytomX Therapeutics Alternatives Innate Pharma Alternatives biote Alternatives Bright Minds Biosciences Alternatives Cybin Alternatives ProQR Therapeutics Alternatives Inhibrx Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:APLT) was last updated on 6/12/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | SponsoredElon’s NEXT Big IPO?Cancel your internet TODAY!? 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