Ardelyx (ARDX) Competitors $6.21 -0.21 (-3.27%) Closing price 09/19/2025 04:00 PM EasternExtended Trading$6.21 0.00 (0.00%) As of 09/19/2025 07:36 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock ARDX vs. AXSM, NUVL, TGTX, MRUS, CRSP, PTCT, KRYS, PCVX, ACAD, and ACLXShould you be buying Ardelyx stock or one of its competitors? The main competitors of Ardelyx include Axsome Therapeutics (AXSM), Nuvalent (NUVL), TG Therapeutics (TGTX), Merus (MRUS), CRISPR Therapeutics (CRSP), PTC Therapeutics (PTCT), Krystal Biotech (KRYS), Vaxcyte (PCVX), ACADIA Pharmaceuticals (ACAD), and Arcellx (ACLX). These companies are all part of the "pharmaceutical products" industry. Ardelyx vs. Its Competitors Axsome Therapeutics Nuvalent TG Therapeutics Merus CRISPR Therapeutics PTC Therapeutics Krystal Biotech Vaxcyte ACADIA Pharmaceuticals Arcellx Axsome Therapeutics (NASDAQ:AXSM) and Ardelyx (NASDAQ:ARDX) are both medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, media sentiment, profitability, analyst recommendations, institutional ownership, earnings, valuation and dividends. Do analysts prefer AXSM or ARDX? Axsome Therapeutics currently has a consensus target price of $177.86, suggesting a potential upside of 53.39%. Ardelyx has a consensus target price of $11.70, suggesting a potential upside of 88.41%. Given Ardelyx's higher possible upside, analysts clearly believe Ardelyx is more favorable than Axsome Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Axsome Therapeutics 0 Sell rating(s) 0 Hold rating(s) 13 Buy rating(s) 2 Strong Buy rating(s) 3.13Ardelyx 0 Sell rating(s) 1 Hold rating(s) 7 Buy rating(s) 2 Strong Buy rating(s) 3.10 Which has preferable valuation and earnings, AXSM or ARDX? Ardelyx has lower revenue, but higher earnings than Axsome Therapeutics. Ardelyx is trading at a lower price-to-earnings ratio than Axsome Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAxsome Therapeutics$385.69M15.00-$287.22M-$5.07-22.87Ardelyx$333.61M4.49-$39.14M-$0.23-27.00 Which has more risk & volatility, AXSM or ARDX? Axsome Therapeutics has a beta of 0.54, indicating that its stock price is 46% less volatile than the S&P 500. Comparatively, Ardelyx has a beta of 0.74, indicating that its stock price is 26% less volatile than the S&P 500. Does the media refer more to AXSM or ARDX? In the previous week, Axsome Therapeutics had 20 more articles in the media than Ardelyx. MarketBeat recorded 24 mentions for Axsome Therapeutics and 4 mentions for Ardelyx. Ardelyx's average media sentiment score of 1.21 beat Axsome Therapeutics' score of 0.73 indicating that Ardelyx is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Axsome Therapeutics 16 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Positive Ardelyx 3 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is AXSM or ARDX more profitable? Ardelyx has a net margin of -14.60% compared to Axsome Therapeutics' net margin of -49.88%. Ardelyx's return on equity of -36.57% beat Axsome Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Axsome Therapeutics-49.88% -283.22% -33.06% Ardelyx -14.60%-36.57%-13.42% Do institutionals & insiders hold more shares of AXSM or ARDX? 81.5% of Axsome Therapeutics shares are owned by institutional investors. Comparatively, 58.9% of Ardelyx shares are owned by institutional investors. 22.3% of Axsome Therapeutics shares are owned by company insiders. Comparatively, 4.8% of Ardelyx shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term. SummaryAxsome Therapeutics and Ardelyx tied by winning 8 of the 16 factors compared between the two stocks. Get Ardelyx News Delivered to You Automatically Sign up to receive the latest news and ratings for ARDX and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding ARDX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart ARDX vs. The Competition Export to ExcelMetricArdelyxMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.55B$2.58B$5.80B$10.40BDividend YieldN/A55.37%5.63%4.60%P/E Ratio-27.0023.0276.8226.78Price / Sales4.49689.96532.95124.28Price / CashN/A175.2537.9961.55Price / Book8.515.3513.746.40Net Income-$39.14M$32.95M$3.30B$271.80M7 Day Performance-6.05%0.90%2.65%3.48%1 Month Performance3.67%5.76%6.04%9.89%1 Year Performance1.31%-3.43%80.14%28.51% Ardelyx Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)ARDXArdelyx4.3859 of 5 stars$6.21-3.3%$11.70+88.4%+3.7%$1.55B$333.61M-27.0090Positive NewsAXSMAxsome Therapeutics4.8602 of 5 stars$129.29+3.3%$177.86+37.6%+22.9%$6.25B$385.69M-25.50380Insider TradeAnalyst RevisionNUVLNuvalent3.0199 of 5 stars$79.83-1.3%$120.91+51.5%-25.7%$5.83BN/A-16.2940Positive NewsInsider TradeTGTXTG Therapeutics4.2926 of 5 stars$32.38+0.5%$46.25+42.8%+28.0%$5.11B$329M87.51290Trending NewsAnalyst ForecastAnalyst RevisionMRUSMerus2.838 of 5 stars$67.19-0.4%$88.75+32.1%+34.3%$5.10B$36.13M-12.2237Analyst ForecastCRSPCRISPR Therapeutics2.9404 of 5 stars$54.10-1.4%$71.60+32.3%+25.9%$4.99B$37.31M-9.96460News CoverageAnalyst ForecastPTCTPTC Therapeutics3.886 of 5 stars$56.95-0.5%$69.00+21.2%+67.3%$4.55B$806.78M8.171,410Insider TradeKRYSKrystal Biotech4.9356 of 5 stars$145.20-3.4%$210.38+44.9%-11.3%$4.35B$290.52M29.51210PCVXVaxcyte2.0099 of 5 stars$32.41-1.8%$130.00+301.1%-72.9%$4.29BN/A-7.89160Positive NewsACADACADIA Pharmaceuticals4.2723 of 5 stars$25.39+0.5%$28.88+13.7%+48.7%$4.26B$957.80M19.09510Positive NewsACLXArcellx2.3288 of 5 stars$71.11-2.1%$114.31+60.7%-8.9%$4.03B$107.94M-20.7980Insider Trade Related Companies and Tools Related Companies AXSM Competitors NUVL Competitors TGTX Competitors MRUS Competitors CRSP Competitors PTCT Competitors KRYS Competitors PCVX Competitors ACAD Competitors ACLX Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:ARDX) was last updated on 9/20/2025 by MarketBeat.com Staff From Our PartnersREVEALED: Something Big Happening Behind White House Doorswhat I just learned about what’s unfolding in the White House is truly stunning… And you need to see it for...Paradigm Press | SponsoredCrypto Gets Official Government Backing—Here's the WinnerTrump Just Signed the GENIUS Act—One Coin is About to Explode We're at the BEGINNING of smart money really ...Crypto 101 Media | SponsoredCollege grad makes $64,000 a monthA Wall Street legend just helped train our own proprietary AI system in the stock market (a project that took ...Stansberry Research | SponsoredFront-Run Buffett's Shocking Gold MoveA Historic Gold Announcement Is About to Rock Wall Street? 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