Ardelyx (ARDX) Competitors $4.41 -0.11 (-2.43%) Closing price 07/18/2025 04:00 PM EasternExtended Trading$4.39 -0.02 (-0.45%) As of 07/18/2025 07:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock ARDX vs. KRYS, AKRO, RNA, PTCT, ACLX, MRUS, ZLAB, SRRK, ACAD, and VKTXShould you be buying Ardelyx stock or one of its competitors? The main competitors of Ardelyx include Krystal Biotech (KRYS), Akero Therapeutics (AKRO), Avidity Biosciences (RNA), PTC Therapeutics (PTCT), Arcellx (ACLX), Merus (MRUS), Zai Lab (ZLAB), Scholar Rock (SRRK), ACADIA Pharmaceuticals (ACAD), and Viking Therapeutics (VKTX). These companies are all part of the "pharmaceutical products" industry. Ardelyx vs. Its Competitors Krystal Biotech Akero Therapeutics Avidity Biosciences PTC Therapeutics Arcellx Merus Zai Lab Scholar Rock ACADIA Pharmaceuticals Viking Therapeutics Ardelyx (NASDAQ:ARDX) and Krystal Biotech (NASDAQ:KRYS) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, earnings, media sentiment, analyst recommendations, dividends, valuation, profitability and institutional ownership. Which has preferable valuation & earnings, ARDX or KRYS? Krystal Biotech has lower revenue, but higher earnings than Ardelyx. Ardelyx is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioArdelyx$333.61M3.16-$39.14M-$0.22-20.05Krystal Biotech$290.52M14.67$89.16M$4.1635.45 Do institutionals & insiders hold more shares of ARDX or KRYS? 58.9% of Ardelyx shares are held by institutional investors. Comparatively, 86.3% of Krystal Biotech shares are held by institutional investors. 4.8% of Ardelyx shares are held by company insiders. Comparatively, 13.7% of Krystal Biotech shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth. Which has more risk and volatility, ARDX or KRYS? Ardelyx has a beta of 0.6, indicating that its share price is 40% less volatile than the S&P 500. Comparatively, Krystal Biotech has a beta of 0.67, indicating that its share price is 33% less volatile than the S&P 500. Does the media prefer ARDX or KRYS? In the previous week, Krystal Biotech had 19 more articles in the media than Ardelyx. MarketBeat recorded 30 mentions for Krystal Biotech and 11 mentions for Ardelyx. Krystal Biotech's average media sentiment score of -0.13 beat Ardelyx's score of -0.19 indicating that Krystal Biotech is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Ardelyx 2 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 1 Very Negative mention(s) Neutral Krystal Biotech 11 Very Positive mention(s) 1 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Do analysts rate ARDX or KRYS? Ardelyx currently has a consensus price target of $10.89, suggesting a potential upside of 146.91%. Krystal Biotech has a consensus price target of $213.75, suggesting a potential upside of 44.93%. Given Ardelyx's higher probable upside, research analysts plainly believe Ardelyx is more favorable than Krystal Biotech.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Ardelyx 0 Sell rating(s) 1 Hold rating(s) 8 Buy rating(s) 1 Strong Buy rating(s) 3.00Krystal Biotech 0 Sell rating(s) 1 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 3.00 Is ARDX or KRYS more profitable? Krystal Biotech has a net margin of 37.17% compared to Ardelyx's net margin of -14.86%. Krystal Biotech's return on equity of 14.64% beat Ardelyx's return on equity.Company Net Margins Return on Equity Return on Assets Ardelyx-14.86% -34.45% -13.81% Krystal Biotech 37.17%14.64%13.28% SummaryKrystal Biotech beats Ardelyx on 12 of the 15 factors compared between the two stocks. Get Ardelyx News Delivered to You Automatically Sign up to receive the latest news and ratings for ARDX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding ARDX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart ARDX vs. The Competition Export to ExcelMetricArdelyxMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.08B$2.46B$5.55B$9.40BDividend YieldN/A1.80%3.75%4.03%P/E Ratio-20.058.9428.0119.82Price / Sales3.16709.92432.8198.20Price / CashN/A164.7736.1658.27Price / Book6.045.008.125.65Net Income-$39.14M$30.99M$3.25B$257.91M7 Day Performance-1.78%1.69%1.68%3.38%1 Month Performance22.16%9.20%7.30%11.11%1 Year Performance-19.96%0.43%32.89%18.99% Ardelyx Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)ARDXArdelyx4.1578 of 5 stars$4.41-2.4%$10.89+146.9%-19.7%$1.08B$333.61M-20.0590Analyst RevisionKRYSKrystal Biotech4.5465 of 5 stars$150.41+1.5%$213.75+42.1%-26.6%$4.35B$290.52M36.16210Insider TradeAnalyst RevisionAKROAkero Therapeutics3.6777 of 5 stars$52.73+2.2%$82.50+56.5%+92.3%$4.20BN/A-27.0430Insider TradeRNAAvidity Biosciences2.1807 of 5 stars$33.57+6.7%$66.35+97.7%-24.6%$4.05B$8.93M-11.19190High Trading VolumePTCTPTC Therapeutics4.4424 of 5 stars$49.46+1.9%$65.00+31.4%+45.2%$3.92B$806.78M7.601,410News CoverageInsider TradeAnalyst RevisionACLXArcellx2.5401 of 5 stars$69.92+1.4%$111.23+59.1%+8.6%$3.85B$76.81M-23.3880Positive NewsMRUSMerus1.9294 of 5 stars$55.62+2.1%$84.64+52.2%+15.4%$3.85B$36.13M-13.6337News CoverageInsider TradeZLABZai Lab3.3156 of 5 stars$34.28+4.7%$54.28+58.3%+78.6%$3.81B$398.99M-13.771,869SRRKScholar Rock3.0783 of 5 stars$38.59+3.1%$42.67+10.6%+365.4%$3.66B$33.19M-15.25140Analyst ForecastInsider TradeACADACADIA Pharmaceuticals3.9843 of 5 stars$21.89+4.3%$27.88+27.3%+25.3%$3.66B$957.80M15.98510VKTXViking Therapeutics4.637 of 5 stars$31.63+1.7%$87.15+175.5%-36.1%$3.55BN/A-27.5020Positive NewsUpcoming Earnings Related Companies and Tools Related Companies KRYS Competitors AKRO Competitors RNA Competitors PTCT Competitors ACLX Competitors MRUS Competitors ZLAB Competitors SRRK Competitors ACAD Competitors VKTX Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:ARDX) was last updated on 7/19/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredPresidential Bombshell: $150T Resource to Be Released as soon as this Summer?Something extraordinary is happening in Washington. 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