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Zai Lab (ZLAB) Competitors

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$27.00 +0.52 (+1.96%)
As of 09/3/2026 04:00 PM Eastern

ZLAB vs. IONS, PRAX, SMMT, ABVX, and KRYS

Should you buy Zai Lab stock or one of its competitors? Zai Lab's main competitors and comparable companies include Ionis Pharmaceuticals (IONS), Praxis Precision Medicines (PRAX), Summit Therapeutics (SMMT), Abivax (ABVX), and Krystal Biotech (KRYS). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Zai Lab compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and Zai Lab (NASDAQ:ZLAB) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, dividends, risk, institutional ownership, valuation, profitability, media sentiment and analyst recommendations.

Ionis Pharmaceuticals has a beta of 0.42, suggesting that its stock price is 58% less volatile than the broader market. Comparatively, Zai Lab has a beta of 0.83, suggesting that its stock price is 17% less volatile than the broader market.

In the previous week, Ionis Pharmaceuticals had 22 more articles in the media than Zai Lab. MarketBeat recorded 26 mentions for Ionis Pharmaceuticals and 4 mentions for Zai Lab. Ionis Pharmaceuticals' average media sentiment score of 1.18 beat Zai Lab's score of 0.34 indicating that Ionis Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
17 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive
Zai Lab
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. Comparatively, 41.7% of Zai Lab shares are owned by institutional investors. 1.8% of Ionis Pharmaceuticals shares are owned by company insiders. Comparatively, 4.9% of Zai Lab shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Zai Lab has a net margin of -41.86% compared to Ionis Pharmaceuticals' net margin of -64.76%. Zai Lab's return on equity of -27.43% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-64.76% -111.08% -17.41%
Zai Lab -41.86%-27.43%-16.72%

Ionis Pharmaceuticals currently has a consensus target price of $94.15, suggesting a potential upside of 61.96%. Zai Lab has a consensus target price of $37.25, suggesting a potential upside of 37.96%. Given Ionis Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts clearly believe Ionis Pharmaceuticals is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

Zai Lab has lower revenue, but higher earnings than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Zai Lab, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M10.23-$381.39M-$3.46N/A
Zai Lab$460.16M6.68-$175.54M-$1.71N/A

Summary

Zai Lab beats Ionis Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Zai Lab compare to Praxis Precision Medicines?

Praxis Precision Medicines (NASDAQ:PRAX) and Zai Lab (NASDAQ:ZLAB) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their valuation, institutional ownership, analyst recommendations, media sentiment, profitability, earnings, dividends and risk.

Zai Lab has higher revenue and earnings than Praxis Precision Medicines. Praxis Precision Medicines is trading at a lower price-to-earnings ratio than Zai Lab, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Praxis Precision Medicines$8.55M1,159.74-$303.27M-$12.93N/A
Zai Lab$460.16M6.68-$175.54M-$1.71N/A

Praxis Precision Medicines has a net margin of 0.00% compared to Zai Lab's net margin of -41.86%. Zai Lab's return on equity of -27.43% beat Praxis Precision Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Praxis Precision MedicinesN/A -34.15% -32.42%
Zai Lab -41.86%-27.43%-16.72%

67.8% of Praxis Precision Medicines shares are held by institutional investors. Comparatively, 41.7% of Zai Lab shares are held by institutional investors. 3.0% of Praxis Precision Medicines shares are held by company insiders. Comparatively, 4.9% of Zai Lab shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

In the previous week, Praxis Precision Medicines and Praxis Precision Medicines both had 4 articles in the media. Praxis Precision Medicines' average media sentiment score of 1.02 beat Zai Lab's score of 0.34 indicating that Praxis Precision Medicines is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Praxis Precision Medicines
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Zai Lab
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Praxis Precision Medicines has a beta of 2.76, meaning that its stock price is 176% more volatile than the broader market. Comparatively, Zai Lab has a beta of 0.83, meaning that its stock price is 17% less volatile than the broader market.

Praxis Precision Medicines currently has a consensus price target of $585.95, suggesting a potential upside of 64.99%. Zai Lab has a consensus price target of $37.25, suggesting a potential upside of 37.96%. Given Praxis Precision Medicines' stronger consensus rating and higher probable upside, analysts clearly believe Praxis Precision Medicines is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Praxis Precision Medicines
2 Sell rating(s)
0 Hold rating(s)
16 Buy rating(s)
3 Strong Buy rating(s)
2.95
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

Summary

Praxis Precision Medicines beats Zai Lab on 9 of the 16 factors compared between the two stocks.

How does Zai Lab compare to Summit Therapeutics?

Zai Lab (NASDAQ:ZLAB) and Summit Therapeutics (NASDAQ:SMMT) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their dividends, risk, analyst recommendations, earnings, profitability, media sentiment, institutional ownership and valuation.

In the previous week, Summit Therapeutics had 12 more articles in the media than Zai Lab. MarketBeat recorded 16 mentions for Summit Therapeutics and 4 mentions for Zai Lab. Summit Therapeutics' average media sentiment score of 0.62 beat Zai Lab's score of 0.34 indicating that Summit Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zai Lab
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Summit Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive

41.7% of Zai Lab shares are owned by institutional investors. Comparatively, 4.6% of Summit Therapeutics shares are owned by institutional investors. 4.9% of Zai Lab shares are owned by company insiders. Comparatively, 83.5% of Summit Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Zai Lab presently has a consensus price target of $37.25, indicating a potential upside of 37.96%. Summit Therapeutics has a consensus price target of $24.07, indicating a potential upside of 40.53%. Given Summit Therapeutics' higher probable upside, analysts plainly believe Summit Therapeutics is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71
Summit Therapeutics
1 Sell rating(s)
8 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.44

Zai Lab has higher revenue and earnings than Summit Therapeutics. Zai Lab is trading at a lower price-to-earnings ratio than Summit Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zai Lab$460.16M6.68-$175.54M-$1.71N/A
Summit TherapeuticsN/AN/A-$1.08B-$1.12N/A

Zai Lab has a beta of 0.83, suggesting that its stock price is 17% less volatile than the broader market. Comparatively, Summit Therapeutics has a beta of -1.24, suggesting that its stock price is 224% less volatile than the broader market.

Summit Therapeutics has a net margin of 0.00% compared to Zai Lab's net margin of -41.86%. Zai Lab's return on equity of -27.43% beat Summit Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Zai Lab-41.86% -27.43% -16.72%
Summit Therapeutics N/A -168.94%-141.92%

Summary

Summit Therapeutics beats Zai Lab on 8 of the 15 factors compared between the two stocks.

How does Zai Lab compare to Abivax?

Abivax (NASDAQ:ABVX) and Zai Lab (NASDAQ:ZLAB) are both mid-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their dividends, analyst recommendations, valuation, profitability, earnings, media sentiment, institutional ownership and risk.

In the previous week, Zai Lab had 3 more articles in the media than Abivax. MarketBeat recorded 4 mentions for Zai Lab and 1 mentions for Abivax. Abivax's average media sentiment score of 1.19 beat Zai Lab's score of 0.34 indicating that Abivax is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Abivax
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zai Lab
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Zai Lab has higher revenue and earnings than Abivax. Abivax is trading at a lower price-to-earnings ratio than Zai Lab, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
AbivaxN/AN/A-$380.27M-$5.21N/A
Zai Lab$460.16M6.68-$175.54M-$1.71N/A

Abivax presently has a consensus price target of $156.50, indicating a potential upside of 37.23%. Zai Lab has a consensus price target of $37.25, indicating a potential upside of 37.96%. Given Zai Lab's higher possible upside, analysts plainly believe Zai Lab is more favorable than Abivax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Abivax
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.80
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

47.9% of Abivax shares are owned by institutional investors. Comparatively, 41.7% of Zai Lab shares are owned by institutional investors. 4.9% of Zai Lab shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Abivax has a net margin of 0.00% compared to Zai Lab's net margin of -41.86%. Zai Lab's return on equity of -27.43% beat Abivax's return on equity.

Company Net Margins Return on Equity Return on Assets
AbivaxN/A -99.02% -70.26%
Zai Lab -41.86%-27.43%-16.72%

Abivax has a beta of 0.96, suggesting that its share price is 4% less volatile than the broader market. Comparatively, Zai Lab has a beta of 0.83, suggesting that its share price is 17% less volatile than the broader market.

Summary

Zai Lab beats Abivax on 10 of the 16 factors compared between the two stocks.

How does Zai Lab compare to Krystal Biotech?

Krystal Biotech (NASDAQ:KRYS) and Zai Lab (NASDAQ:ZLAB) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, analyst recommendations, dividends, valuation, risk, profitability, institutional ownership and media sentiment.

In the previous week, Krystal Biotech had 5 more articles in the media than Zai Lab. MarketBeat recorded 9 mentions for Krystal Biotech and 4 mentions for Zai Lab. Krystal Biotech's average media sentiment score of 1.52 beat Zai Lab's score of 0.34 indicating that Krystal Biotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Krystal Biotech
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Zai Lab
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Krystal Biotech currently has a consensus target price of $365.40, indicating a potential downside of 1.63%. Zai Lab has a consensus target price of $37.25, indicating a potential upside of 37.96%. Given Zai Lab's higher probable upside, analysts plainly believe Zai Lab is more favorable than Krystal Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Krystal Biotech
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

Krystal Biotech has higher earnings, but lower revenue than Zai Lab. Zai Lab is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Krystal Biotech$389.13M28.26$204.83M$7.9846.55
Zai Lab$460.16M6.68-$175.54M-$1.71N/A

86.3% of Krystal Biotech shares are owned by institutional investors. Comparatively, 41.7% of Zai Lab shares are owned by institutional investors. 13.1% of Krystal Biotech shares are owned by insiders. Comparatively, 4.9% of Zai Lab shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Krystal Biotech has a beta of 0.54, meaning that its stock price is 46% less volatile than the broader market. Comparatively, Zai Lab has a beta of 0.83, meaning that its stock price is 17% less volatile than the broader market.

Krystal Biotech has a net margin of 54.82% compared to Zai Lab's net margin of -41.86%. Krystal Biotech's return on equity of 19.34% beat Zai Lab's return on equity.

Company Net Margins Return on Equity Return on Assets
Krystal Biotech54.82% 19.34% 17.65%
Zai Lab -41.86%-27.43%-16.72%

Summary

Krystal Biotech beats Zai Lab on 13 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ZLAB and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ZLAB vs. The Competition

MetricZai LabBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$3.01B$4.03B$7.26B$12.73B
Dividend YieldN/A3.60%2.53%8.86%
P/E Ratio-15.7912.66273.2925.38
Price / Sales6.681,309.08613.4592.55
Price / CashN/A106.8777.8252.26
Price / Book5.0616.2912.896.14
Net Income-$175.54M-$22.72M$3.47B$349.01M
7 Day Performance3.53%0.34%0.60%-0.27%
1 Month Performance46.02%8.52%5.73%0.68%
1 Year Performance-10.00%52.66%25.35%14.84%

Zai Lab Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ZLAB
Zai Lab
2.5634 of 5 stars
$27.00
+2.0%
$37.25
+38.0%
-13.7%$3.01B$460.16MN/A1,784
IONS
Ionis Pharmaceuticals
3.7346 of 5 stars
$63.57
+2.5%
$94.15
+48.1%
-3.9%$10.31B$944MN/A1,402
PRAX
Praxis Precision Medicines
3.175 of 5 stars
$368.02
0.0%
$585.95
+59.2%
+662.9%$10.28B$8.55MN/A110
SMMT
Summit Therapeutics
3.4991 of 5 stars
$13.36
+4.9%
$24.07
+80.2%
-27.2%$10.16BN/AN/A110
ABVX
Abivax
2.5152 of 5 stars
$117.93
+1.5%
$156.50
+32.7%
+36.3%$10.13BN/AN/A61

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This page (NASDAQ:ZLAB) was last updated on 9/4/2026 by MarketBeat.com Staff.
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