Denali Therapeutics (DNLI) Earnings Date, Estimates & Call Transcripts $13.06 -0.20 (-1.51%) Closing price 04:00 PM EasternExtended Trading$13.38 +0.32 (+2.45%) As of 05:11 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Earnings Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Denali Therapeutics Earnings Summary Denali Therapeutics posted Q2 2025 earnings on August 11, 2025, reporting an EPS of -$0.72, which topped the consensus estimate of -$0.74 by $0.02. With a trailing EPS of -$2.80, Denali Therapeutics' earnings are expected to decrease next year, from ($2.71) to ($3.03) per share. Upcoming Q3 Earnings DateNov. 5Before Market OpensEstimatedConsensus EPS (Aug. 11) -$0.74 Actual EPS (Aug. 11) -$0.72 Beat By $0.02 Q2 2025 Earnings ResourcesQ2 2025 Earnings Report Press Release (8-K) Quarterly Report (10-Q)SEC FilingDNLI Upcoming EarningsDenali Therapeutics' next earnings date is estimated for Wednesday, November 5, 2025, based on past reporting schedules. Powered by Get Denali Therapeutics Earnings Alerts Want to stay updated on the latest earnings announcements and upcoming reports? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Denali Therapeutics and other key companies, straight to your inbox. Sign Up View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. 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The dark blue line represents the company's actual revenue. The light blue line represents the company's estimated revenue based on the consensus of Wall Street analysts for each quarter. Denali Therapeutics Analyst EPS EstimatesQuarterNumber of EstimatesLow EstimateHigh EstimateAverage EstimateQ1 20254-$0.83-$0.69-$0.78Q2 20255-$0.86-$0.68-$0.77Q3 20256-$0.84-$0.68-$0.76Q4 20256-$0.84-$0.71-$0.80 FY 2025 21 -$3.37 -$2.76 -$3.11 Q1 20262-$0.85-$0.79-$0.82Q2 20262-$0.79-$0.78-$0.79Q3 20262-$0.79-$0.78-$0.79Q4 20262-$0.78-$0.77-$0.78 FY 2026 8 -$3.21 -$3.12 -$3.17 Q1 20271-$0.74-$0.74-$0.74 Denali Therapeutics Earnings History by Quarter Custom Range 3 Months 6 Months Year-to-Date 1 Year 2 Years 3 Years 5 Years 10 Years Time Frame Start Date End Date Export to Excel DateQuarterConsensus EstimateReported EPSBeat/MissGAAP EPSRevenue EstimateActual RevenueDetails 11/5/2025(Estimated)--------8/11/2025Q2 2025-$0.74-$0.72+$0.02-$0.72$5.64M-5/6/2025Q1 2025-$0.71-$0.78 -$0.07-$0.78$3.24M-2/27/2025Q4 2024-$0.75-$0.67+$0.08-$0.67$12.75M-11/6/2024Q3 2024-$0.60-$0.63 -$0.03-$0.63$6.30M-8/1/2024Q2 2024-$0.68-$0.59+$0.09-$0.59$10.00M$1.00M5/7/2024Q1 2024-$0.69-$0.68+$0.01-$0.68$14.02M-2/27/2024Q4 2023-$0.81-$0.86 -$0.05-$0.86$3.38M-11/7/2023Q3 2023-$0.81-$0.72+$0.09-$0.72$11.16M$1.30M Denali Therapeutics Earnings - Frequently Asked Questions When is Denali Therapeutics' earnings date? Denali Therapeutics has not confirmed its next earnings publication date, but the company's estimated earnings date is Wednesday, November 5th, 2025 based off last year's report dates. Learn more on DNLI's earnings history. Did Denali Therapeutics beat their earnings estimates last quarter? In the previous quarter, Denali Therapeutics (NASDAQ:DNLI) reported ($0.72) earnings per share (EPS) to beat the analysts' consensus estimate of ($0.74) by $0.02. Learn more on analysts' earnings estimate vs. DNLI's actual earnings. How can I view Denali Therapeutics' earnings report? Denali Therapeutics' earnings report can be found in their filing with the SEC. View SEC filing How much revenue does Denali Therapeutics generate each year? Denali Therapeutics (NASDAQ:DNLI) has a recorded annual revenue of $330.53 million. How much profit does Denali Therapeutics generate each year? Denali Therapeutics (NASDAQ:DNLI) has a recorded net income of -$422.77 million. DNLI has generated -$2.80 earnings per share over the last four quarters. What is Denali Therapeutics' EPS forecast for next year? Denali Therapeutics' earnings are expected to decrease from ($2.71) per share to ($3.03) per share in the next year. 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