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Denali Therapeutics (DNLI) Institutional Ownership

Denali Therapeutics logo
$19.71 -0.70 (-3.43%)
Closing price 05/7/2026 04:00 PM Eastern
Extended Trading
$19.50 -0.21 (-1.06%)
As of 05/7/2026 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)

Current
Institutional Ownership
Percentage
92.92%
Number of
Institutional Buyers
(last 12 months)
158
Total
Institutional Inflows
(last 12 months)
$758.95M
Number of
Institutional Sellers
(last 12 months)
89
Total
Institutional Outflows
(last 12 months)
$250.54M
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DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/7/2026Dimensional Fund Advisors LP2,692,175$51.69M0.0%+13.4%1.697%
5/7/2026KBC Group NV4,943$95K0.0%-21.1%0.003%
5/5/2026 D.A. Davidson & CO.110,235$2.12M0.0%+3.1%0.069%
5/5/2026 Bank of New York Mellon Corp768,039$14.75M0.0%+0.8%0.484%
5/4/2026 Principal Financial Group Inc.1,478,486$28.39M0.0%-3.0%0.932%
5/4/2026 Teachers Retirement System of The State of Kentucky166,181$3.19M0.0%+8.1%0.105%
5/1/2026 Fifth Third Bancorp2,847$55K0.0%N/A0.002%
5/1/2026 Candriam S.C.A.1,099,845$21.12M0.1%-5.7%0.693%
4/27/2026 Y Intercept Hong Kong Ltd78,007$1.50M0.0%-16.6%0.049%
4/22/2026 Pictet Asset Management Holding SA2,558,865$48.44M0.1%+92.5%1.614%
4/22/2026 Sterling Capital Management LLC4,493$86K0.0%-37.9%0.003%
4/21/2026 Contravisory Investment Management Inc.14,451$277K0.1%N/A0.009%
4/20/2026 Breakwater Capital Group15,586$299K0.0%-4.8%0.010%
4/16/2026 SG Americas Securities LLC46,642$896K0.0%-68.8%0.029%
2/27/2026Groupama Asset Managment151,591$2.50M0.0%+11.7%0.103%
2/19/2026T. Rowe Price Investment Management Inc.7,254,132$119.77M0.1%+28.7%4.946%
2/19/2026Invesco Ltd.291,936$4.82M0.0%+17.0%0.199%
2/18/2026Voloridge Investment Management LLC591,461$9.77M0.0%-36.8%0.403%
2/18/2026Vestal Point Capital LP465,000$7.68M0.3%N/A0.317%
2/18/2026Virtus Investment Advisers LLC14,795$244K0.1%+94.1%0.010%
2/18/2026Wellington Management Group LLP54,543$901K0.0%-7.9%0.037%
2/18/2026Susquehanna Portfolio Strategies LLC167,713$2.77M0.0%N/A0.114%
2/18/2026Tudor Investment Corp ET AL53,683$886K0.0%-4.8%0.037%
2/18/2026Millennium Management LLC369,767$6.11M0.0%-71.7%0.252%
2/18/2026Man Group plc48,994$809K0.0%N/A0.033%
2/18/2026Ishara Investments LP70,000$1.16M1.3%N/A0.048%
2/18/2026Casdin Capital LLC1,840,000$30.38M1.9%+106.7%1.255%
2/18/2026Clough Capital Partners L P51,830$856K0.1%N/A0.035%
2/17/2026Guggenheim Capital LLC12,468$206K0.0%-74.8%0.009%
2/17/2026ADAR1 Capital Management LLC52,116$860K0.1%+1.2%0.036%
2/17/2026Burkehill Global Management LP200,000$3.30M0.2%N/A0.136%
2/17/2026AQR Capital Management LLC38,438$635K0.0%+59.2%0.026%
2/17/2026Trexquant Investment LP209,609$3.46M0.0%-51.3%0.143%
2/17/2026Jump Financial LLC40,608$670K0.0%-75.6%0.028%
2/17/2026Price T Rowe Associates Inc. MD3,915,951$64.65M0.0%-14.3%2.670%
2/17/2026T. Rowe Price Investment Management Inc.1,245,994$20.57M0.0%-77.9%0.850%
2/17/2026Ghisallo Capital Management LLC100,000$1.65M0.1%N/A0.068%
2/17/2026State of Wisconsin Investment Board73,581$1.22M0.0%-8.2%0.050%
2/17/2026ExodusPoint Capital Management LP1,023,253$16.89M0.1%N/A0.698%
2/17/2026Royal Bank of Canada11,335$187K0.0%-97.0%0.008%
2/17/2026Graham Capital Management L.P.18,121$299K0.0%-53.9%0.012%
2/17/2026Persistent Asset Partners Ltd5,670$94K0.0%N/A0.004%
2/17/2026Aster Capital Management DIFC Ltd3,451$57K0.0%N/A0.002%
2/17/2026Temasek Holdings Private Ltd7,012,974$115.78M0.4%+30.9%4.782%
2/16/2026Barclays PLC407,359$6.73M0.0%-6.8%0.278%
2/13/2026Marshall Wace LLP763,892$12.61M0.0%-2.9%0.521%
2/13/2026The Manufacturers Life Insurance Company 184,238$3.03M0.0%-10.5%0.126%
2/13/2026Segall Bryant & Hamill LLC537,000$8.87M0.1%+4.7%0.366%
2/13/2026Hudson Bay Capital Management LP450,000$7.43M0.0%+47.5%0.307%
2/13/2026Quarry LP7,000$116K0.0%+60.0%0.005%
2/13/2026Schroder Investment Management Group450,985$7.40M0.0%+115.2%0.308%
2/13/2026Rafferty Asset Management LLC191,567$3.16M0.0%+4.7%0.131%
2/13/2026Headlands Technologies LLC46,383$766K0.1%N/A0.032%
2/13/2026Integrated Wealth Concepts LLC94,582$1.56M0.0%+3.9%0.064%
2/13/2026Alyeska Investment Group L.P.859,108$14.18M0.0%N/A0.586%
2/13/2026Siren L.L.C.1,396,513$23.06M0.7%+70.0%0.952%
2/13/2026Charles Schwab Investment Management Inc.1,200,475$19.82M0.0%+4.3%0.819%
2/13/2026State Street Corp6,263,371$103.41M0.0%+14.6%4.271%
2/13/2026Martingale Asset Management L P18,535$306K0.0%N/A0.013%
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC4,983,726$82.28M0.0%-8.8%3.398%
2/13/2026Wells Fargo & Company MN193,681$3.20M0.0%+85.9%0.132%
2/12/2026HRT Financial LP78,352$1.29M0.0%N/A0.053%
2/12/2026MetLife Investment Management LLC75,164$1.24M0.0%-4.9%0.051%
2/12/2026Renaissance Technologies LLC10,700$177K0.0%-82.1%0.007%
2/12/2026Dimensional Fund Advisors LP2,374,303$39.20M0.0%+0.7%1.619%
2/12/2026Ensign Peak Advisors Inc515,721$8.52M0.0%-3.4%0.352%
2/12/2026Marex Group plc287,001$4.74M0.0%-1.4%0.196%
2/12/2026Ironwood Investment Management LLC50,933$841K0.4%-3.5%0.035%
2/12/2026Alps Advisors Inc.120,718$1.99M0.0%+71.9%0.082%
2/12/2026Swiss National Bank273,800$4.52M0.0%+2.4%0.187%
2/12/2026Polen Capital Management LLC26,900$444K0.0%N/A0.018%
2/12/2026Monashee Investment Management LLC91,620$1.51M0.9%N/A0.062%
2/12/2026 Nuveen LLC275,508$4.55M0.0%-3.3%0.188%
2/11/2026 Deutsche Bank AG105,086$1.74M0.0%-49.4%0.072%
2/11/2026Franklin Resources Inc.60,270$995K0.0%-6.8%0.041%
2/11/2026Capital Research Global Investors3,729,244$61.57M0.0%-21.7%2.543%
2/11/2026WINTON GROUP Ltd12,700$210K0.0%N/A0.009%
2/11/2026State of Wyoming2,686$44K0.0%+24.7%0.002%
2/10/2026TD Asset Management Inc339,410$5.60M0.0%-14.0%0.231%
2/10/2026 1492 Capital Management LLC67,487$1.11M0.4%N/A0.046%
2/10/2026Goldman Sachs Group Inc.3,835,803$63.33M0.0%+77.3%2.615%
2/10/2026Norges Bank5,119,622$84.53M0.0%N/A3.491%
2/10/2026Eurizon Capital SGR S.p.A.5,045$83K0.0%N/A0.003%
2/10/2026 SBI Okasan Asset Management Co.Ltd.18,000$298K0.0%N/A0.012%
2/10/2026Intech Investment Management LLC52,632$869K0.0%+12.5%0.036%
2/9/2026Geode Capital Management LLC3,458,131$57.10M0.0%-0.2%2.358%
2/9/2026Knights of Columbus Asset Advisors LLC49,007$809K0.0%-2.4%0.033%
2/9/2026Employees Retirement System of Texas47,177$779K0.0%+7.8%0.032%
2/9/2026 Fisher Asset Management LLC2,589,403$42.75M0.0%+58.7%1.766%
2/6/2026 PSP Research LLC31,762$524K0.5%N/A0.022%
2/6/2026 Intrust Bank NA11,164$184K0.0%+5.6%0.008%
2/6/2026 Handelsbanken Fonder AB43,800$723K0.0%+14.4%0.030%
2/6/2026 Profund Advisors LLC71,634$1.18M0.0%+78.4%0.049%
2/6/2026 ProShare Advisors LLC30,682$507K0.0%+10.1%0.021%
2/6/2026 HighTower Advisors LLC11,757$194K0.0%-44.9%0.008%
2/4/2026Pier 88 Investment Partners LLC68,200$1.13M0.3%+1.1%0.047%
1/30/2026 State of New Jersey Common Pension Fund D47,410$783K0.0%-66.1%0.032%
1/29/2026 D.A. Davidson & CO.106,933$1.77M0.0%N/A0.073%
1/29/2026 Pictet Asset Management Holding SA1,329,108$21.98M0.0%+166.3%0.906%
1/29/2026 UBS Group AG2,404,704$39.70M0.0%+19.5%1.640%


DNLI Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of DNLI shares?

During the previous two years, 249 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were Vanguard Group Inc. ($215.59M), Baillie Gifford & Co. ($203.25M), FMR LLC ($163.44M), T. Rowe Price Investment Management Inc. ($119.77M), Temasek Holdings Private Ltd ($115.78M), State Street Corp ($103.41M), and Norges Bank ($84.53M).Learn more on Denali Therapeutics' institutional investors.

What percentage of Denali Therapeutics' stock is owned by institutional investors?

92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings.

Which institutional investors have been buying Denali Therapeutics' stock?

Of the 218 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Norges Bank ($10.13M), FMR LLC ($7.78M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), Holocene Advisors LP ($3.17M), Capital Research Global Investors ($3.15M), Wellington Management Group LLP ($2.47M), and Goldman Sachs Group Inc. ($2.29M).

How much institutional buying is happening at Denali Therapeutics?

Institutional investors have bought a total of 49,604,477 shares in the last 24 months. This purchase volume represents approximately $758.95M in transactions.

Which of Denali Therapeutics' major shareholders have been selling company stock?

Of the 88 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($4.39M), Marshall Wace LLP ($1.42M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($1.28M), Capital Research Global Investors ($1.03M), Millennium Management LLC ($937.40K), Camber Capital Management LP ($850K), and Price T Rowe Associates Inc. MD ($652.42K).

How much institutional selling is happening at Denali Therapeutics?

Institutional investors have sold a total of 16,135,105 shares in the last 24 months. This volume of shares sold represents approximately $250.54M in transactions.


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This page (NASDAQ:DNLI) was last updated on 5/8/2026 by MarketBeat.com Staff.
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