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NASDAQ:GUTS

Fractyl Health (GUTS) Stock Price, News & Analysis

Fractyl Health logo
$4.42 +0.19 (+4.49%)
Closing price 10/9/2026 04:00 PM Eastern
Extended Trading
$4.50 +0.08 (+1.81%)
As of 10/9/2026 07:51 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

About Fractyl Health Stock (NASDAQ:GUTS)

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Key Stats

Today's Range
$4.20
▼
$4.55
50-Day Range
$4.23
▼
$9.41
52-Week Range
$4.14
▼
$29.34
Volume
197,876 shs
Average Volume
180,418 shs
Market Capitalization
$58.61 million
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$66.00
Consensus Rating
Hold

Company Overview

Fractyl Health, Inc. is a clinical-stage biotechnology company focused on developing therapies for metabolic diseases, including type 2 diabetes and obesity. The company’s approach is based on targeting the biology of the gastrointestinal system and developing treatments intended to address underlying disease mechanisms rather than relying solely on chronic medication.

Fractyl Health’s lead product candidate is Revita, an investigational, minimally invasive endoscopic procedure designed to resurface the duodenal lining. The company has studied Revita in patients with type 2 diabetes and is evaluating its potential to improve metabolic control. Fractyl is also developing a gene therapy platform intended to enable durable, potentially long-term production of metabolic hormones such as GLP-1, with the goal of creating a one-time treatment approach for obesity and related metabolic conditions.

Founded in 2015 and headquartered in Lexington, Massachusetts, Fractyl Health conducts clinical-stage research and development for its metabolic disease programs. The company was co-founded and is led by Harith Rajagopalan, M.D., Ph.D., who serves as chief executive officer. Fractyl Health became a publicly traded company in 2024 and trades on the Nasdaq under the symbol GUTS.

AI Generated. May Contain Errors.

Fractyl Health Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
55th Percentile Overall Score

GUTS MarketRank™: 

Fractyl Health scored higher than 55% of companies evaluated by MarketBeat, and ranked 495th out of 883 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Fractyl Health has received a consensus rating of Hold. The company's average rating score is 2.40, and is based on no strong buy ratings, 3 buy ratings, 1 hold rating, and 1 sell rating.

  • Upside Potential

    Fractyl Health has a consensus price target of $66.00, representing about 1,393.2% upside from its current price of $4.42.

  • Amount of Analyst Coverage

    Fractyl Health has only been the subject of 1 research reports in the past 90 days.

  • Read more about Fractyl Health's stock forecast and price target.
  • Earnings Growth

    Earnings for Fractyl Health are expected to grow in the coming year, from ($6.32) to ($4.98) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Fractyl Health is -0.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Fractyl Health is -0.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Fractyl Health has a P/B Ratio of 5.33. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

  • Read more about Fractyl Health's valuation and earnings.
  • Percentage of Shares Shorted

    17.70% of the float of Fractyl Health has been sold short.
  • Short Interest Ratio / Days to Cover

    Fractyl Health has a short interest ratio ("days to cover") of 1.2, which is generally considered an acceptable ratio of short interest to trading volume.
  • Change versus previous month

    Short interest in Fractyl Health has recently decreased by 20.25%, indicating that investor sentiment is improving significantly.
  • Dividend Yield

    Fractyl Health does not currently pay a dividend.

  • Dividend Growth

    Fractyl Health does not have a long track record of dividend growth.

  • News Sentiment

    Fractyl Health has a news sentiment score of 0.04. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.66 average news sentiment score of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 18 news articles for Fractyl Health this week, compared to 5 articles on an average week.
  • Search Interest

    12 people have searched for GUTS on MarketBeat in the last 30 days. This is an increase of 9% compared to the previous 30 days.
  • MarketBeat Follows

    3 people have added Fractyl Health to their MarketBeat watchlist in the last 30 days. This is an increase of 200% compared to the previous 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Fractyl Health insiders have not sold or bought any company stock.

  • Percentage Held by Insiders

    8.36% of the stock of Fractyl Health is held by insiders.

  • Percentage Held by Institutions

    Fractyl Health has minimal institutional ownership at this time.

  • Read more about Fractyl Health's insider trading history.
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GUTS Stock News Headlines

Trump’s issues shocking Executive Order on U.S. Dollar
Three days into his second term, President Trump signed Executive Order 14178 a move the press barely covered. Buried inside is what some call the legal groundwork for the biggest change to American money in over a century, with a key Treasury vote potentially as soon as January 18. Ian King, Chief Strategist at Strategic Fortunes, breaks down what the order could mean for the dollar and the financial system.tc pixel
See More Headlines

GUTS Stock Analysis - Frequently Asked Questions

Fractyl Health's stock was trading at $26.40 at the beginning of the year. Since then, GUTS stock has decreased by 83.3% and is now trading at $4.42.

Fractyl Health, Inc. (NASDAQ:GUTS) announced its earnings results on Monday, August, 10th. The company reported ($1.44) EPS for the quarter, topping the consensus estimate of ($1.62) by $0.18.
Read the conference call transcript
.

Fractyl Health's stock reverse split on Monday, October 5th 2026.A 1-12 reverse split was announced. The number of shares owned by shareholders was adjusted after the market closes on Sunday, October 4th 2026. An investor that had 100 shares of stock prior to the reverse split would have 8 shares after the split.

Fractyl Health (GUTS) raised $110 million in an initial public offering (IPO) on Friday, February 2nd 2024. The company issued 7,333,333 shares at a price of $14.00-$16.00 per share.

Shares of GUTS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Fractyl Health investors own include SoFi Technologies (SOFI), NVIDIA (NVDA), Meta Platforms (META), Tesla (TSLA), Alphabet (GOOG), JPMorgan Chase & Co. (JPM) and Advanced Micro Devices (AMD).

Company Calendar

Last Earnings
8/10/2026
Today
10/10/2026
Next Earnings (Estimated)
11/11/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:GUTS
Previous Symbol
NASDAQ:GUTS
CIK
1572616
Fax
N/A
Employees
73
Year Founded
2010

Price Target and Rating

High Price Target
$96.00
Low Price Target
$24.00
Potential Upside/Downside
+1,393.2%
Consensus Rating
Hold
Rating Score (0-4)
2.40
Research Coverage
5 Analysts

Profitability

EPS (Trailing Twelve Months)
($0.88)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$140.95 million
Net Margins
N/A
Pretax Margin
N/A
Return on Equity
-1,362.10%
Return on Assets
-84.89%

Debt

Debt-to-Equity Ratio
1.41
Current Ratio
3.15
Quick Ratio
3.15

Sales & Book Value

Annual Sales
$90 thousand
Price / Sales
651.21
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$0.83 per share
Price / Book
5.33

Miscellaneous

Outstanding Shares
13,260,000
Free Float
12,151,000
Market Cap
$58.61 million
Optionable
N/A
Beta
2.42

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This page (NASDAQ:GUTS) was last updated on 10/10/2026 by MarketBeat.com Staff.
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