| 8/18/2026 | Stonepine Capital Management LLC | 96,172 | $539.04M | 0.3% | N/A | 0.847% | |
| 8/15/2026 | Trails Edge Capital Partners LP | 282,004 | $1.66M | 0.0% | N/A | 2.485% | |
| 8/14/2026 | Hsbc Holdings PLC | 34,228 | $208K | 0.0% | N/A | 0.321% | |
| 8/14/2026 | Cable Car Capital LP | 781,599 | $4.61M | 0.1% | N/A | 7.339% | |
| 8/11/2026 | Blue Owl Capital Holdings LP | 917,692 | $5.41M | 0.8% | N/A | 8.617% | |
| 8/7/2026 | BlackRock Inc. | 135,090 | $797K | 0.0% | N/A | 1.268% | |
| 5/15/2026 | Rangeley Capital LLC | 32,590 | $163K | 0.1% | +78.6% | 0.306% | |
| 5/14/2026 | Renaissance Technologies LLC | 81,696 | $408K | 0.0% | +23.6% | 0.767% | |
| 5/6/2026 | BML Capital Management LLC | 200,730 | $1.00M | 0.6% | +13.4% | 1.885% | |
| 3/20/2026 | Hsbc Holdings PLC | 34,228 | $233K | 0.0% | N/A | 0.306% | |
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| 2/18/2026 | XTX Topco Ltd | 12,177 | $84K | 0.0% | -72.9% | 0.109% | |
| 2/18/2026 | Millennium Management LLC | 11,454 | $79K | 0.0% | N/A | 0.102% | |
| 2/16/2026 | Squarepoint Ops LLC | 48,237 | $333K | 0.0% | +99.6% | 0.431% | |
| 2/16/2026 | Barclays PLC | 10,797 | $74K | 0.0% | +170.8% | 0.097% | |
| 2/12/2026 | Jane Street Group LLC | 14,896 | $103K | 0.0% | N/A | 0.133% | |
| 2/12/2026 | DRW Securities LLC | 43,768 | $302K | 0.0% | N/A | 0.391% | |
| 2/12/2026 | Renaissance Technologies LLC | 66,096 | $456K | 0.0% | +76.8% | 0.591% | |
| 2/12/2026 | Monashee Investment Management LLC | 91,621 | $632K | 0.4% | N/A | 0.820% | |
| 2/11/2026 | T3 Companies LLC | 13,200 | $91K | 0.1% | N/A | 0.118% | |
| 2/10/2026 | Goldman Sachs Group Inc. | 10,950 | $76K | 0.0% | N/A | 0.098% | |
| 2/9/2026 | Geode Capital Management LLC | 54,146 | $374K | 0.0% | +13.5% | 0.484% | |
| 2/9/2026 | Blue Owl Capital Holdings LP | 823,785 | $5.68M | 0.4% | +52.3% | 7.368% | |
| 2/6/2026 | Nano Cap New Millennium Growth Fund L P | 26,500 | $183K | 0.2% | N/A | 0.237% | |
| 2/3/2026 | BML Capital Management LLC | 177,026 | $1.22M | 1.1% | -3.0% | 1.583% | |
| 11/17/2025 | Jacobs Levy Equity Management Inc. | 17,708 | $144K | 0.0% | N/A | 0.442% | |
| 11/17/2025 | NewEdge Advisors LLC | 12,960 | $106K | 0.0% | N/A | 0.323% | |
| 11/17/2025 | Citadel Advisors LLC | 122,247 | $996K | 0.0% | N/A | 3.052% | |
| 11/14/2025 | Deep Track Capital LP | 878,516 | $7.16M | 0.2% | N/A | 21.935% | |
| 11/14/2025 | Bridgeway Capital Management LLC | 12,774 | $104K | 0.0% | N/A | 0.319% | |
| 11/14/2025 | Squarepoint Ops LLC | 24,170 | $197K | 0.0% | N/A | 0.603% | |
| 11/14/2025 | Atlas Venture Life Science Advisors LLC | 377,814 | $3.08M | 0.4% | N/A | 9.434% | |
| 11/13/2025 | Blue Owl Capital Holdings LP | 540,924 | $4.41M | 1.4% | N/A | 13.489% | |
| 11/10/2025 | Aldebaran Capital LLC | 19,562 | $159K | 0.1% | N/A | 0.488% | |
| 11/10/2025 | BML Capital Management LLC | 182,509 | $1.49M | 1.1% | N/A | 4.551% | |
| 11/7/2025 | Vanguard Group Inc. | 233,358 | $1.90M | 0.0% | N/A | 5.819% | |
| 6/27/2025 | Goldman Sachs Group Inc. | 76,464 | $98K | 0.0% | +62.4% | 0.158% | |
| 5/21/2025 | Acadian Asset Management LLC | 209,568 | $266K | 0.0% | -27.3% | 0.434% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 76,464 | $98K | 0.0% | +62.4% | 0.158% | |
| 5/16/2025 | Jacobs Levy Equity Management Inc. | 245,485 | $314K | 0.0% | -25.0% | 0.509% | |
| 5/13/2025 | Gilead Sciences Inc. | 1,159,145 | $1.48M | 0.1% | -42.3% | 2.402% | |
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| 5/13/2025 | Aldebaran Capital LLC | 247,795 | $317K | 0.3% | N/A | 0.513% | |
| 5/8/2025 | XTX Topco Ltd | 56,452 | $72K | 0.0% | +350.6% | 0.117% | |
| 5/7/2025 | BML Capital Management LLC | 3,710,803 | $4.75M | 3.7% | +3.5% | 7.690% | |
| 4/30/2025 | Peapod Lane Capital LLC | 296,437 | $379K | 0.4% | -41.6% | 0.614% | |
| 2/17/2025 | Squarepoint Ops LLC | 43,640 | $72K | 0.0% | N/A | 0.090% | |
| 2/17/2025 | Two Sigma Investments LP | 100,778 | $165K | 0.0% | -35.7% | 0.209% | |
| 2/17/2025 | Two Sigma Advisers LP | 157,400 | $258K | 0.0% | -22.1% | 0.326% | |
| 2/17/2025 | Millennium Management LLC | 199,684 | $327K | 0.0% | -19.9% | 0.414% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 327,410 | $537K | 0.0% | -15.8% | 0.678% | |
| 2/17/2025 | Citadel Advisors LLC | 80,368 | $132K | 0.0% | -51.3% | 0.167% | |
| 2/17/2025 | BVF Inc. IL | 4,006,564 | $6.57M | 0.2% | -16.0% | 8.302% | |
| 2/17/2025 | BNP Paribas Financial Markets | 44,040 | $72K | 0.0% | N/A | 0.091% | |
| 2/14/2025 | Northern Trust Corp | 57,565 | $94K | 0.0% | +19.7% | 0.119% | |
| 2/14/2025 | Vazirani Asset Management LLC | 25,000 | $41K | 0.1% | -78.4% | 0.052% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 800,000 | $1.31M | 0.0% | -19.0% | 1.658% | |
| 2/14/2025 | Gilead Sciences Inc. | 2,008,338 | $3.29M | 0.2% | N/A | 4.161% | |
| 2/13/2025 | Renaissance Technologies LLC | 330,200 | $542K | 0.0% | -17.6% | 0.684% | |
| 2/12/2025 | Geode Capital Management LLC | 327,962 | $538K | 0.0% | +21.0% | 0.680% | |
| 2/12/2025 | JPMorgan Chase & Co. | 155,741 | $255K | 0.0% | +18,244.1% | 0.323% | |
| 2/11/2025 | Prudential Financial Inc. | 18,200 | $30K | 0.0% | -38.9% | 0.038% | |
| 2/7/2025 | BBR Partners LLC | 70,000 | $115K | 0.0% | -46.2% | 0.145% | |
| 2/7/2025 | BML Capital Management LLC | 3,585,866 | $5.88M | 3.7% | +395.8% | 7.430% | |
| 1/29/2025 | Peapod Lane Capital LLC | 507,868 | $833K | 0.8% | N/A | 1.052% | |
| 11/16/2024 | Geode Capital Management LLC | 271,026 | $469K | 0.0% | +5.6% | 0.562% | |
| 11/15/2024 | Jane Street Group LLC | 37,270 | $64K | 0.0% | -33.3% | 0.077% | |
| 11/15/2024 | Jacobs Levy Equity Management Inc. | 388,748 | $673K | 0.0% | -8.4% | 0.806% | |
| 11/15/2024 | Point72 Asia Singapore Pte. Ltd. | 22,146 | $38K | 0.0% | -51.3% | 0.046% | |
| 11/14/2024 | NEA Management Company LLC | 600,063 | $1.04M | 0.1% | +5.3% | 1.243% | |
| 11/14/2024 | BBR Partners LLC | 130,000 | $225K | 0.0% | +550.0% | 0.269% | |
| 11/13/2024 | FMR LLC | 38,374 | $66K | 0.0% | +94.1% | 0.080% | |
| 11/5/2024 | BML Capital Management LLC | 723,288 | $1.25M | 0.7% | +23.6% | 1.499% | |
| 9/16/2024 | Point72 Asia Singapore Pte. Ltd. | 45,520 | $75K | 0.0% | N/A | 0.094% | |
| 8/15/2024 | Blue Owl Capital Holdings LP | 4,091,118 | $6.75M | 1.9% | +5.1% | 8.478% | |
| 8/15/2024 | AQR Capital Management LLC | 21,861 | $36K | 0.0% | N/A | 0.045% | |
| 8/15/2024 | Point72 Asia Singapore Pte. Ltd. | 45,520 | $75K | 0.0% | N/A | 0.094% | |
| 8/14/2024 | Marshall Wace LLP | 44,933 | $74K | 0.0% | -49.3% | 0.093% | |
| 8/12/2024 | XTX Topco Ltd | 16,607 | $27K | 0.0% | -52.9% | 0.034% | |
| 8/12/2024 | Vanguard Personalized Indexing Management LLC | 18,310 | $30K | 0.0% | N/A | 0.038% | |
| 8/10/2024 | Sofinnova Investments Inc. | 382,616 | $631K | 0.0% | +230.7% | 0.793% | |
| 8/9/2024 | Renaissance Technologies LLC | 476,400 | $786K | 0.0% | -38.7% | 0.987% | |
| 8/8/2024 | JBF Capital Inc. | 72,647 | $120K | 0.0% | N/A | 0.151% | |
| 8/6/2024 | Acadian Asset Management LLC | 325,713 | $536K | 0.0% | +15.2% | 0.675% | |
| 8/5/2024 | BBR Partners LLC | 20,000 | $33K | 0.0% | N/A | 0.041% | |
| 7/30/2024 | Deuterium Capital Management LLC | 80,578 | $133K | 0.2% | N/A | 0.167% | |
| 5/16/2024 | Jacobs Levy Equity Management Inc. | 513,440 | $729K | 0.0% | +813.7% | 1.064% | |
| 5/10/2024 | Acadian Asset Management LLC | 282,782 | $400K | 0.0% | +1,201.8% | 0.586% | |
| 5/7/2024 | Marquette Asset Management LLC | 72,890 | $104K | 0.0% | N/A | 0.151% | |
| 2/15/2024 | BVF Inc. IL | 4,769,164 | $9.40M | 0.2% | +50.5% | 9.883% | |
| 2/14/2024 | Vestal Point Capital LP | 322,671 | $636K | 0.1% | N/A | 0.669% | |
| 1/12/2024 | SG Americas Securities LLC | 20,222 | $40K | 0.0% | +88.5% | 0.042% | |
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| 11/15/2023 | Laurion Capital Management LP | 534,657 | $2.32M | 0.0% | +3.3% | 1.264% | |
| 11/15/2023 | Adage Capital Partners GP L.L.C. | 407,900 | $1.77M | 0.0% | +5.2% | 0.964% | |
| 11/13/2023 | CHI Advisors LLC | 2,180,934 | $9.44M | 2.8% | +2.8% | 5.156% | |
| 11/13/2023 | FMR LLC | 4,458,134 | $19.30M | 0.0% | -12.1% | 10.539% | |
| 11/9/2023 | OUP Management Co. LLC | 26,833 | $116K | 0.3% | N/A | 0.063% | |
| 11/7/2023 | Barclays PLC | 206,545 | $894K | 0.0% | +2.1% | 0.488% | |
| 10/24/2023 | Bank of New York Mellon Corp | 69,239 | $300K | 0.0% | +11.1% | 0.164% | |
| 10/13/2023 | SG Americas Securities LLC | 10,727 | $46K | 0.0% | N/A | 0.025% | |
| 10/3/2023 | Vida Ventures Advisors LLC | 225,192 | $975K | 1.5% | N/A | 0.532% | |
| 8/22/2023 | CHI Advisors LLC | 2,122,040 | $13.92M | 4.2% | +27.8% | 5.851% | |