IO Biotech (IOBT) Competitors $1.78 +0.03 (+1.71%) Closing price 09/4/2025 04:00 PM EasternExtended Trading$1.78 +0.00 (+0.28%) As of 04:05 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock IOBT vs. PRTC, RGNX, ERAS, ITOS, CYRX, REPL, CMPS, ESPR, IVA, and CMPXShould you be buying IO Biotech stock or one of its competitors? The main competitors of IO Biotech include PureTech Health (PRTC), REGENXBIO (RGNX), Erasca (ERAS), iTeos Therapeutics (ITOS), CryoPort (CYRX), Replimune Group (REPL), COMPASS Pathways (CMPS), Esperion Therapeutics (ESPR), Inventiva (IVA), and Compass Therapeutics (CMPX). These companies are all part of the "pharmaceutical products" industry. IO Biotech vs. Its Competitors PureTech Health REGENXBIO Erasca iTeos Therapeutics CryoPort Replimune Group COMPASS Pathways Esperion Therapeutics Inventiva Compass Therapeutics PureTech Health (NASDAQ:PRTC) and IO Biotech (NASDAQ:IOBT) are both medical companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, valuation, earnings, profitability, dividends, analyst recommendations, institutional ownership and media sentiment. Do institutionals & insiders believe in PRTC or IOBT? 0.0% of PureTech Health shares are owned by institutional investors. Comparatively, 54.8% of IO Biotech shares are owned by institutional investors. 5.3% of PureTech Health shares are owned by insiders. Comparatively, 4.8% of IO Biotech shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth. Does the media prefer PRTC or IOBT? In the previous week, PureTech Health and PureTech Health both had 2 articles in the media. PureTech Health's average media sentiment score of 0.11 beat IO Biotech's score of 0.00 indicating that PureTech Health is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment PureTech Health 0 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral IO Biotech 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Is PRTC or IOBT more profitable? PureTech Health's return on equity of 0.00% beat IO Biotech's return on equity.Company Net Margins Return on Equity Return on Assets PureTech HealthN/A N/A N/A IO Biotech N/A -281.82%-169.29% Which has stronger earnings and valuation, PRTC or IOBT? PureTech Health has higher revenue and earnings than IO Biotech. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioPureTech Health$4.83M82.72$27.78MN/AN/AIO BiotechN/AN/A-$95.49M-$1.58-1.13 Do analysts recommend PRTC or IOBT? PureTech Health currently has a consensus price target of $45.00, indicating a potential upside of 171.79%. IO Biotech has a consensus price target of $8.00, indicating a potential upside of 349.44%. Given IO Biotech's higher probable upside, analysts clearly believe IO Biotech is more favorable than PureTech Health.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score PureTech Health 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 3.50IO Biotech 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 3.33 Which has more risk & volatility, PRTC or IOBT? PureTech Health has a beta of 1.11, suggesting that its share price is 11% more volatile than the S&P 500. Comparatively, IO Biotech has a beta of 0.41, suggesting that its share price is 59% less volatile than the S&P 500. SummaryPureTech Health beats IO Biotech on 8 of the 11 factors compared between the two stocks. Get IO Biotech News Delivered to You Automatically Sign up to receive the latest news and ratings for IOBT and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding IOBT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart IOBT vs. The Competition Export to ExcelMetricIO BiotechMED IndustryMedical SectorNASDAQ ExchangeMarket CapN/A$3.13B$5.76B$9.85BDividend YieldN/A2.28%6.67%4.51%P/E Ratio-1.1320.8975.9926.43Price / SalesN/A458.96546.94119.09Price / CashN/A44.5237.0558.92Price / Book2.519.9310.916.06Net Income-$95.49M-$53.38M$3.29B$266.28M7 Day Performance12.66%0.63%0.18%-0.32%1 Month Performance-17.21%6.31%6.26%3.44%1 Year Performance98.86%11.63%51.54%23.11% IO Biotech Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)IOBTIO Biotech2.3333 of 5 stars$1.78+1.7%$8.00+349.4%+84.3%$0.00N/A-1.1330Short Interest ↑PRTCPureTech Health2.3482 of 5 stars$19.14+4.0%$45.00+135.1%-23.7%$458.50M$4.83M0.00100Short Interest ↑RGNXREGENXBIO4.3899 of 5 stars$8.97-0.4%$28.38+216.3%-16.5%$455.13M$83.33M-2.61370News CoveragePositive NewsERASErasca2.8718 of 5 stars$1.59-0.6%$4.29+169.5%-47.0%$453.87MN/A-3.53120Analyst ForecastITOSiTeos Therapeutics3.5147 of 5 stars$10.13-0.6%$15.50+53.0%N/A$450.45M$35M-2.1790News CoverageShort Interest ↓CYRXCryoPort4.1148 of 5 stars$8.81-1.8%$12.00+36.2%+3.4%$449.10M$228.38M6.621,186News CoveragePositive NewsREPLReplimune Group4.2238 of 5 stars$5.49-3.2%$7.67+39.6%-44.3%$442.58MN/A-1.69210Trending NewsGap DownCMPSCOMPASS Pathways2.5355 of 5 stars$4.58-0.7%$16.29+255.6%-24.8%$442.29MN/A-2.49120Positive NewsESPREsperion Therapeutics3.9172 of 5 stars$2.15-0.9%$7.00+225.6%+39.0%$437.52M$332.31M-4.39200Options VolumeIVAInventiva2.7337 of 5 stars$4.66+4.3%$10.40+123.2%+144.5%$428.09M$9.95M0.00100News CoverageAnalyst ForecastShort Interest ↑Gap DownCMPXCompass Therapeutics2.7057 of 5 stars$3.02flat$12.89+326.8%+118.8%$417.61M$850K-6.7120Positive News Related Companies and Tools Related Companies PureTech Health Competitors REGENXBIO Competitors Erasca Competitors iTeos Therapeutics Competitors CryoPort Competitors Replimune Group Competitors COMPASS Pathways Competitors Esperion Therapeutics Competitors Inventiva Competitors Compass Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:IOBT) was last updated on 9/5/2025 by MarketBeat.com Staff From Our PartnersHow “Trump’s New Dollar” Could Impact Your WealthPresident Trump just signed a game-changing law… That could soon upgrade the U.S. dollar in your checking a...Brownstone Research | SponsoredForget Tesla — This Tiny AI Stock Is Musk’s Real PlayWhile Wall Street focused on Tesla’s earnings, Elon Musk was quietly building a supercomputer so powerful it c...Behind the Markets | SponsoredRetire Comfortably with These New Monthly Income ETFs?Too many retirees lie awake at night, worried their savings won’t last. 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