IO Biotech (IOBT) Competitors $1.31 +0.26 (+24.76%) Closing price 08/12/2025 04:00 PM EasternExtended Trading$1.30 -0.01 (-0.76%) As of 07:52 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock IOBT vs. PHAT, KROS, RLAY, BCAX, TLRY, ORGO, XNCR, MRVI, TSHA, and TRMLShould you be buying IO Biotech stock or one of its competitors? The main competitors of IO Biotech include Phathom Pharmaceuticals (PHAT), Keros Therapeutics (KROS), Relay Therapeutics (RLAY), Bicara Therapeutics (BCAX), Tilray Brands (TLRY), Organogenesis (ORGO), Xencor (XNCR), Maravai LifeSciences (MRVI), Taysha Gene Therapies (TSHA), and Tourmaline Bio (TRML). These companies are all part of the "pharmaceutical products" industry. IO Biotech vs. Its Competitors Phathom Pharmaceuticals Keros Therapeutics Relay Therapeutics Bicara Therapeutics Tilray Brands Organogenesis Xencor Maravai LifeSciences Taysha Gene Therapies Tourmaline Bio Phathom Pharmaceuticals (NASDAQ:PHAT) and IO Biotech (NASDAQ:IOBT) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, analyst recommendations, valuation, dividends, risk, profitability, earnings and media sentiment. Which has better earnings and valuation, PHAT or IOBT? IO Biotech has lower revenue, but higher earnings than Phathom Pharmaceuticals. Phathom Pharmaceuticals is trading at a lower price-to-earnings ratio than IO Biotech, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioPhathom Pharmaceuticals$55.25M13.33-$334.33M-$4.73-2.19IO BiotechN/AN/A-$95.49M-$1.49-0.88 Do analysts prefer PHAT or IOBT? Phathom Pharmaceuticals currently has a consensus price target of $17.50, suggesting a potential upside of 68.59%. IO Biotech has a consensus price target of $8.67, suggesting a potential upside of 561.58%. Given IO Biotech's stronger consensus rating and higher possible upside, analysts plainly believe IO Biotech is more favorable than Phathom Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Phathom Pharmaceuticals 0 Sell rating(s) 1 Hold rating(s) 4 Buy rating(s) 1 Strong Buy rating(s) 3.00IO Biotech 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 3.33 Does the media prefer PHAT or IOBT? In the previous week, IO Biotech had 2 more articles in the media than Phathom Pharmaceuticals. MarketBeat recorded 16 mentions for IO Biotech and 14 mentions for Phathom Pharmaceuticals. Phathom Pharmaceuticals' average media sentiment score of 0.08 beat IO Biotech's score of -0.07 indicating that Phathom Pharmaceuticals is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Phathom Pharmaceuticals 2 Very Positive mention(s) 2 Positive mention(s) 7 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral IO Biotech 3 Very Positive mention(s) 1 Positive mention(s) 5 Neutral mention(s) 3 Negative mention(s) 2 Very Negative mention(s) Neutral Which has more volatility & risk, PHAT or IOBT? Phathom Pharmaceuticals has a beta of 0.45, meaning that its share price is 55% less volatile than the S&P 500. Comparatively, IO Biotech has a beta of 0.44, meaning that its share price is 56% less volatile than the S&P 500. Is PHAT or IOBT more profitable? IO Biotech has a net margin of 0.00% compared to Phathom Pharmaceuticals' net margin of -289.51%. Phathom Pharmaceuticals' return on equity of 0.00% beat IO Biotech's return on equity.Company Net Margins Return on Equity Return on Assets Phathom Pharmaceuticals-289.51% N/A -90.40% IO Biotech N/A -162.55%-125.08% Do insiders and institutionals have more ownership in PHAT or IOBT? 99.0% of Phathom Pharmaceuticals shares are owned by institutional investors. Comparatively, 54.8% of IO Biotech shares are owned by institutional investors. 24.1% of Phathom Pharmaceuticals shares are owned by insiders. Comparatively, 2.3% of IO Biotech shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term. SummaryPhathom Pharmaceuticals beats IO Biotech on 8 of the 15 factors compared between the two stocks. Get IO Biotech News Delivered to You Automatically Sign up to receive the latest news and ratings for IOBT and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding IOBT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart IOBT vs. The Competition Export to ExcelMetricIO BiotechMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$69.18M$2.99B$5.49B$9.68BDividend YieldN/A2.29%4.64%4.14%P/E Ratio-0.8819.9630.3825.31Price / SalesN/A354.13449.32102.31Price / CashN/A40.7837.7258.50Price / Book1.857.658.316.01Net Income-$95.49M-$54.75M$3.26B$265.10M7 Day Performance-33.16%0.95%1.53%1.39%1 Month Performance-10.88%8.12%3.73%2.43%1 Year Performance-14.38%10.97%41.10%24.74% IO Biotech Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)IOBTIO Biotech3.0023 of 5 stars$1.31+24.8%$8.67+561.6%+0.8%$69.18MN/A-0.8830Trending NewsAnalyst ForecastGap UpHigh Trading VolumePHATPhathom Pharmaceuticals3.2793 of 5 stars$8.64+3.5%$17.50+102.5%-13.7%$582.95M$55.25M-1.65110KROSKeros Therapeutics2.6166 of 5 stars$14.62+2.1%$30.56+109.0%-69.4%$581.61M$3.55M-81.22100Trending NewsEarnings ReportAnalyst RevisionRLAYRelay Therapeutics1.9679 of 5 stars$3.65+8.6%$17.67+384.0%-48.5%$576.05M$10.01M-1.64330Earnings ReportBCAXBicara TherapeuticsN/A$11.12+5.6%$31.86+186.5%N/A$574.27MN/A0.0032News CoveragePositive NewsEarnings ReportAnalyst ForecastTLRYTilray Brands2.9131 of 5 stars$0.61+6.9%$1.92+215.3%-46.8%$572.39M$821.31M-0.262,650Trending NewsOptions VolumeGap UpORGOOrganogenesis4.3367 of 5 stars$4.60+2.0%$6.50+41.3%+102.1%$572.11M$482.04M-27.06950Earnings ReportXNCRXencor3.5534 of 5 stars$7.95-0.4%$28.00+252.2%-50.9%$567.94M$110.49M-2.60280Trending NewsEarnings ReportAnalyst RevisionMRVIMaravai LifeSciences3.3847 of 5 stars$2.27+2.3%$6.64+192.5%-69.1%$565.34M$259.18M-1.99610Trending NewsAnalyst ForecastGap UpTSHATaysha Gene Therapies3.0104 of 5 stars$2.71+3.0%$8.17+201.4%+42.6%$564.56M$8.33M-7.97180News CoverageEarnings ReportAnalyst ForecastTRMLTourmaline Bio1.8979 of 5 stars$21.59-0.8%$49.33+128.5%+52.9%$558.91MN/A-6.7344Upcoming Earnings Related Companies and Tools Related Companies Phathom Pharmaceuticals Competitors Keros Therapeutics Competitors Relay Therapeutics Competitors Bicara Therapeutics Competitors Tilray Brands Competitors Organogenesis Competitors Xencor Competitors Maravai LifeSciences Competitors Taysha Gene Therapies Competitors Tourmaline Bio Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:IOBT) was last updated on 8/13/2025 by MarketBeat.com Staff From Our PartnersYour blueprint for crypto wealthMark August 12th on your calendar. 27 of crypto's most successful minds are about to reveal everything…Crypto 101 Media | SponsoredTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredThe Robotics Revolution has arrived … and one $7 stock could take off as a result.Something big is brewing in Washington. 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