Ironwood Pharmaceuticals (IRWD) Competitors $0.72 -0.08 (-9.69%) Closing price 06/11/2025 04:00 PM EasternExtended Trading$0.72 +0.00 (+0.04%) As of 04:00 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock IRWD vs. RIGL, EBS, VSTM, XOMA, VNDA, LXRX, CDXS, ACHV, AGEN, and SGMOShould you be buying Ironwood Pharmaceuticals stock or one of its competitors? The main competitors of Ironwood Pharmaceuticals include Rigel Pharmaceuticals (RIGL), Emergent BioSolutions (EBS), Verastem (VSTM), XOMA (XOMA), Vanda Pharmaceuticals (VNDA), Lexicon Pharmaceuticals (LXRX), Codexis (CDXS), Achieve Life Sciences (ACHV), Agenus (AGEN), and Sangamo Therapeutics (SGMO). These companies are all part of the "biotechnology" industry. Ironwood Pharmaceuticals vs. Its Competitors Rigel Pharmaceuticals Emergent BioSolutions Verastem XOMA Vanda Pharmaceuticals Lexicon Pharmaceuticals Codexis Achieve Life Sciences Agenus Sangamo Therapeutics Rigel Pharmaceuticals (NASDAQ:RIGL) and Ironwood Pharmaceuticals (NASDAQ:IRWD) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, media sentiment, earnings, institutional ownership, profitability, community ranking, valuation, dividends and risk. Which has higher earnings and valuation, RIGL or IRWD? Rigel Pharmaceuticals has higher earnings, but lower revenue than Ironwood Pharmaceuticals. Ironwood Pharmaceuticals is trading at a lower price-to-earnings ratio than Rigel Pharmaceuticals, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioRigel Pharmaceuticals$203.08M1.86-$25.09M$2.0710.24Ironwood Pharmaceuticals$317.68M0.37-$1.00B-$0.20-3.61 Do analysts recommend RIGL or IRWD? Rigel Pharmaceuticals presently has a consensus price target of $36.40, suggesting a potential upside of 71.78%. Ironwood Pharmaceuticals has a consensus price target of $4.78, suggesting a potential upside of 562.79%. Given Ironwood Pharmaceuticals' higher probable upside, analysts plainly believe Ironwood Pharmaceuticals is more favorable than Rigel Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Rigel Pharmaceuticals 0 Sell rating(s) 3 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 2.40Ironwood Pharmaceuticals 0 Sell rating(s) 7 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 2.13 Which has more volatility and risk, RIGL or IRWD? Rigel Pharmaceuticals has a beta of 1.29, suggesting that its stock price is 29% more volatile than the S&P 500. Comparatively, Ironwood Pharmaceuticals has a beta of 0.24, suggesting that its stock price is 76% less volatile than the S&P 500. Does the MarketBeat Community believe in RIGL or IRWD? Ironwood Pharmaceuticals received 48 more outperform votes than Rigel Pharmaceuticals when rated by MarketBeat users. However, 68.88% of users gave Rigel Pharmaceuticals an outperform vote while only 60.73% of users gave Ironwood Pharmaceuticals an outperform vote. CompanyUnderperformOutperformRigel PharmaceuticalsOutperform Votes46768.88% Underperform Votes21131.12% Ironwood PharmaceuticalsOutperform Votes51560.73% Underperform Votes33339.27% Do institutionals & insiders believe in RIGL or IRWD? 66.2% of Rigel Pharmaceuticals shares are held by institutional investors. 9.5% of Rigel Pharmaceuticals shares are held by insiders. Comparatively, 12.7% of Ironwood Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term. Does the media favor RIGL or IRWD? In the previous week, Rigel Pharmaceuticals had 7 more articles in the media than Ironwood Pharmaceuticals. MarketBeat recorded 8 mentions for Rigel Pharmaceuticals and 1 mentions for Ironwood Pharmaceuticals. Rigel Pharmaceuticals' average media sentiment score of 1.40 beat Ironwood Pharmaceuticals' score of 0.43 indicating that Rigel Pharmaceuticals is being referred to more favorably in the media. Company Overall Sentiment Rigel Pharmaceuticals Positive Ironwood Pharmaceuticals Neutral Is RIGL or IRWD more profitable? Rigel Pharmaceuticals has a net margin of 2.46% compared to Ironwood Pharmaceuticals' net margin of -0.65%. Ironwood Pharmaceuticals' return on equity of -0.96% beat Rigel Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Rigel Pharmaceuticals2.46% -14.80% 3.03% Ironwood Pharmaceuticals -0.65%-0.96%0.74% SummaryRigel Pharmaceuticals beats Ironwood Pharmaceuticals on 13 of the 18 factors compared between the two stocks. Get Ironwood Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for IRWD and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding IRWD and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart IRWD vs. The Competition Export to ExcelMetricIronwood PharmaceuticalsPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$116.79M$6.85B$5.57B$8.62BDividend YieldN/A2.56%5.28%4.18%P/E Ratio-24.068.7827.1720.06Price / Sales0.37255.64410.88157.10Price / CashN/A65.8538.2534.64Price / Book-0.336.557.094.70Net Income-$1.00B$143.93M$3.23B$247.88M7 Day Performance26.39%3.97%2.91%2.66%1 Month Performance-1.65%11.32%9.09%6.40%1 Year Performance-88.69%4.20%31.75%14.07% Ironwood Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)IRWDIronwood Pharmaceuticals4.5334 of 5 stars$0.72-9.7%$4.78+562.8%-88.5%$116.79M$317.68M-24.06220Gap DownRIGLRigel Pharmaceuticals3.2834 of 5 stars$20.15+4.9%$36.40+80.6%+107.7%$360.12M$203.08M143.94160Positive NewsAnalyst RevisionEBSEmergent BioSolutions4.377 of 5 stars$6.30-0.3%$14.33+127.5%+3.0%$341.95M$930.30M-1.542,420VSTMVerastem3.217 of 5 stars$6.02-19.9%$13.63+126.3%+72.0%$330.79M$10M-1.8950Positive NewsHigh Trading VolumeXOMAXOMA4.2339 of 5 stars$24.22-2.2%$69.50+187.0%+4.5%$289.84M$13.05M-6.9610VNDAVanda Pharmaceuticals4.6414 of 5 stars$4.30-0.9%$16.50+283.7%-23.5%$253.42M$201.35M-13.44290Positive NewsAnalyst RevisionLXRXLexicon Pharmaceuticals2.6702 of 5 stars$0.62-0.8%$3.67+489.9%-63.6%$224.70M$31.21M-0.83140Positive NewsCDXSCodexis3.9704 of 5 stars$2.25-2.2%$8.00+255.6%-28.9%$186.40M$49.82M-2.59250Positive NewsAnalyst RevisionACHVAchieve Life Sciences2.547 of 5 stars$3.90+8.9%$14.33+267.5%-32.1%$135.27MN/A-3.4520Positive NewsHigh Trading VolumeAGENAgenus4.2181 of 5 stars$4.13+20.4%$9.00+117.9%-69.2%$113.23M$99.52M-0.37440High Trading VolumeSGMOSangamo Therapeutics2.1957 of 5 stars$0.47+1.7%$4.50+851.6%-14.6%$110.27M$63.76M-0.63480Positive News Related Companies and Tools Related Companies Rigel Pharmaceuticals Alternatives Emergent BioSolutions Alternatives Verastem Alternatives XOMA Alternatives Vanda Pharmaceuticals Alternatives Lexicon Pharmaceuticals Alternatives Codexis Alternatives Achieve Life Sciences Alternatives Agenus Alternatives Sangamo Therapeutics Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:IRWD) was last updated on 6/12/2025 by MarketBeat.com Staff From Our PartnersTrump’s Exec Order #14154 could be a “Millionaire-Maker”Former Presidential Advisor, Jim Rickards, says Trump could “rewire our economy and hand millions of Americans...Paradigm Press | SponsoredTrump wipes out trillions overnight…Is there anybody more powerful than Donald Trump right now? 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