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Lexicon Pharmaceuticals (LXRX) Competitors

Lexicon Pharmaceuticals logo
$2.33 -0.02 (-0.64%)
As of 11:45 AM Eastern
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LXRX vs. CLDX, BCRX, ZBIO, INVA, and NVAX

Should you buy Lexicon Pharmaceuticals stock or one of its competitors? MarketBeat compares Lexicon Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Lexicon Pharmaceuticals include Celldex Therapeutics (CLDX), BioCryst Pharmaceuticals (BCRX), Zenas BioPharma (ZBIO), Innoviva (INVA), and Novavax (NVAX). These companies are all part of the "biotechnology" industry.

How does Lexicon Pharmaceuticals compare to Celldex Therapeutics?

Celldex Therapeutics (NASDAQ:CLDX) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both medical companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, risk, dividends, profitability, media sentiment and analyst recommendations.

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 5.2% of Celldex Therapeutics shares are owned by company insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Celldex Therapeutics presently has a consensus price target of $54.62, suggesting a potential upside of 45.95%. Lexicon Pharmaceuticals has a consensus price target of $4.55, suggesting a potential upside of 95.70%. Given Lexicon Pharmaceuticals' higher possible upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Celldex Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

Celldex Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -37.46%. Lexicon Pharmaceuticals' return on equity of -18.64% beat Celldex Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Celldex TherapeuticsN/A -50.72% -46.59%
Lexicon Pharmaceuticals -37.46%-18.64%-11.79%

Celldex Therapeutics has a beta of 0.9, indicating that its share price is 10% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.05, indicating that its share price is 5% more volatile than the broader market.

In the previous week, Celldex Therapeutics had 10 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 17 mentions for Celldex Therapeutics and 7 mentions for Lexicon Pharmaceuticals. Lexicon Pharmaceuticals' average media sentiment score of 0.83 beat Celldex Therapeutics' score of 0.74 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Celldex Therapeutics
10 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Lexicon Pharmaceuticals has higher revenue and earnings than Celldex Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Celldex Therapeutics$865K3,395.57-$258.76M-$4.26N/A
Lexicon Pharmaceuticals$49.80M20.74-$50.34M-$0.07N/A

Summary

Lexicon Pharmaceuticals beats Celldex Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to BioCryst Pharmaceuticals?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, valuation, media sentiment, analyst recommendations, profitability, earnings, dividends and institutional ownership.

Lexicon Pharmaceuticals has a net margin of -37.46% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Lexicon Pharmaceuticals' return on equity of -18.64% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-51.71% -76.36% 60.12%
Lexicon Pharmaceuticals -37.46%-18.64%-11.79%

In the previous week, BioCryst Pharmaceuticals had 3 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 10 mentions for BioCryst Pharmaceuticals and 7 mentions for Lexicon Pharmaceuticals. BioCryst Pharmaceuticals' average media sentiment score of 1.13 beat Lexicon Pharmaceuticals' score of 0.83 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioCryst Pharmaceuticals
6 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

BioCryst Pharmaceuticals has a beta of 0.55, suggesting that its stock price is 45% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.05, suggesting that its stock price is 5% more volatile than the broader market.

BioCryst Pharmaceuticals has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$874.84M2.60$263.86M-$1.78N/A
Lexicon Pharmaceuticals$49.80M20.74-$50.34M-$0.07N/A

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 3.8% of BioCryst Pharmaceuticals shares are owned by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

BioCryst Pharmaceuticals currently has a consensus target price of $20.80, indicating a potential upside of 132.01%. Lexicon Pharmaceuticals has a consensus target price of $4.55, indicating a potential upside of 95.70%. Given BioCryst Pharmaceuticals' higher probable upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

Summary

BioCryst Pharmaceuticals beats Lexicon Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Zenas BioPharma?

Zenas BioPharma (NASDAQ:ZBIO) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, analyst recommendations, dividends, valuation, risk, profitability, institutional ownership and media sentiment.

Zenas BioPharma currently has a consensus target price of $44.29, indicating a potential upside of 40.41%. Lexicon Pharmaceuticals has a consensus target price of $4.55, indicating a potential upside of 95.70%. Given Lexicon Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Zenas BioPharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zenas BioPharma
1 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.56
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 22.0% of Zenas BioPharma shares are owned by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Lexicon Pharmaceuticals had 2 more articles in the media than Zenas BioPharma. MarketBeat recorded 7 mentions for Lexicon Pharmaceuticals and 5 mentions for Zenas BioPharma. Zenas BioPharma's average media sentiment score of 1.24 beat Lexicon Pharmaceuticals' score of 0.83 indicating that Zenas BioPharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zenas BioPharma
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Zenas BioPharma has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -37.46%. Lexicon Pharmaceuticals' return on equity of -18.64% beat Zenas BioPharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Zenas BioPharmaN/A -99.99% -58.06%
Lexicon Pharmaceuticals -37.46%-18.64%-11.79%

Lexicon Pharmaceuticals has higher revenue and earnings than Zenas BioPharma. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Zenas BioPharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zenas BioPharma$10M199.11-$377.74M-$8.47N/A
Lexicon Pharmaceuticals$49.80M20.74-$50.34M-$0.07N/A

Zenas BioPharma has a beta of -0.96, meaning that its stock price is 196% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.05, meaning that its stock price is 5% more volatile than the broader market.

Summary

Lexicon Pharmaceuticals beats Zenas BioPharma on 11 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Innoviva?

Innoviva (NASDAQ:INVA) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, risk, media sentiment, earnings, institutional ownership, valuation, dividends and profitability.

In the previous week, Innoviva had 1 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 8 mentions for Innoviva and 7 mentions for Lexicon Pharmaceuticals. Innoviva's average media sentiment score of 1.45 beat Lexicon Pharmaceuticals' score of 0.83 indicating that Innoviva is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Innoviva
6 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

99.1% of Innoviva shares are held by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. 2.0% of Innoviva shares are held by company insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Innoviva has a net margin of 119.89% compared to Lexicon Pharmaceuticals' net margin of -37.46%. Innoviva's return on equity of 33.33% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Innoviva119.89% 33.33% 22.67%
Lexicon Pharmaceuticals -37.46%-18.64%-11.79%

Innoviva currently has a consensus price target of $36.20, suggesting a potential upside of 72.22%. Lexicon Pharmaceuticals has a consensus price target of $4.55, suggesting a potential upside of 95.70%. Given Lexicon Pharmaceuticals' stronger consensus rating and higher possible upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Innoviva.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Innoviva
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

Innoviva has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Innoviva, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Innoviva$420.69M3.69$271.17M$6.013.50
Lexicon Pharmaceuticals$49.80M20.74-$50.34M-$0.07N/A

Innoviva has a beta of 0.34, suggesting that its stock price is 66% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.05, suggesting that its stock price is 5% more volatile than the broader market.

Summary

Innoviva beats Lexicon Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Novavax?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Novavax (NASDAQ:NVAX) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their dividends, media sentiment, risk, analyst recommendations, institutional ownership, profitability, valuation and earnings.

Lexicon Pharmaceuticals presently has a consensus price target of $4.55, indicating a potential upside of 95.70%. Novavax has a consensus price target of $13.00, indicating a potential upside of 78.25%. Given Lexicon Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Lexicon Pharmaceuticals is more favorable than Novavax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75
Novavax
3 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.40

Lexicon Pharmaceuticals has a beta of 1.05, indicating that its share price is 5% more volatile than the broader market. Comparatively, Novavax has a beta of 2.43, indicating that its share price is 143% more volatile than the broader market.

Novavax has a net margin of -14.73% compared to Lexicon Pharmaceuticals' net margin of -37.46%. Novavax's return on equity of -14.82% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-37.46% -18.64% -11.79%
Novavax -14.73%-14.82%1.23%

Novavax has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Novavax, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M20.74-$50.34M-$0.07N/A
Novavax$1.12B1.07$440.30M-$0.58N/A

74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. Comparatively, 53.0% of Novavax shares are held by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are held by insiders. Comparatively, 1.6% of Novavax shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Lexicon Pharmaceuticals had 1 more articles in the media than Novavax. MarketBeat recorded 7 mentions for Lexicon Pharmaceuticals and 6 mentions for Novavax. Lexicon Pharmaceuticals' average media sentiment score of 0.83 beat Novavax's score of 0.15 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Novavax
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Lexicon Pharmaceuticals and Novavax tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LXRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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LXRX vs. The Competition

MetricLexicon PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.04B$3.65B$6.86B$12.37B
Dividend YieldN/A2.13%2.65%10.11%
P/E Ratio-33.3523.0627.4523.66
Price / Sales20.74212.49495.5278.38
Price / CashN/A165.2551.7458.30
Price / Book7.757.929.915.85
Net Income-$50.34M$23.81M$3.61B$336.64M
7 Day Performance1.53%-1.14%-0.29%0.02%
1 Month Performance-3.12%-7.49%-3.96%-5.24%
1 Year Performance117.29%39.62%22.83%17.56%

Lexicon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LXRX
Lexicon Pharmaceuticals
1.8617 of 5 stars
$2.33
-0.6%
$4.55
+95.7%
+129.4%$1.04B$49.80MN/A140
CLDX
Celldex Therapeutics
2.8668 of 5 stars
$35.42
+0.2%
$53.91
+52.2%
+68.7%$2.77B$1.54MN/A150
BCRX
BioCryst Pharmaceuticals
3.5837 of 5 stars
$9.11
-1.9%
$20.80
+128.3%
+12.4%$2.36B$874.84MN/A530
ZBIO
Zenas BioPharma
3.9237 of 5 stars
$30.70
+4.0%
$44.29
+44.3%
+104.9%$1.86B$10MN/AN/A
INVA
Innoviva
3.1718 of 5 stars
$21.28
-2.0%
$36.20
+70.1%
+15.1%$1.60B$411.33M3.54100

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This page (NASDAQ:LXRX) was last updated on 7/31/2026 by MarketBeat.com Staff.
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