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Lexicon Pharmaceuticals (LXRX) Competitors

Lexicon Pharmaceuticals logo
$2.18 -0.23 (-9.54%)
Closing price 04:00 PM Eastern
Extended Trading
$2.20 +0.02 (+0.92%)
As of 06:27 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

LXRX vs. RLAY, PBLS, VKTX, DNLI, and TNGX

Should you buy Lexicon Pharmaceuticals stock or one of its competitors? Lexicon Pharmaceuticals's main competitors and comparable companies include Relay Therapeutics (RLAY), Parabilis Medicines (PBLS), Viking Therapeutics (VKTX), Denali Therapeutics (DNLI), and Tango Therapeutics (TNGX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Lexicon Pharmaceuticals compare to Relay Therapeutics?

Relay Therapeutics (NASDAQ:RLAY) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, analyst recommendations, profitability, earnings, valuation, dividends, institutional ownership and risk.

In the previous week, Relay Therapeutics had 14 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 16 mentions for Relay Therapeutics and 2 mentions for Lexicon Pharmaceuticals. Relay Therapeutics' average media sentiment score of 0.86 beat Lexicon Pharmaceuticals' score of 0.37 indicating that Relay Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Relay Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
6 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Relay Therapeutics currently has a consensus target price of $25.92, indicating a potential upside of 31.56%. Lexicon Pharmaceuticals has a consensus target price of $4.55, indicating a potential upside of 108.72%. Given Lexicon Pharmaceuticals' higher probable upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Relay Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Relay Therapeutics
2 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
2.86
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Lexicon Pharmaceuticals has higher revenue and earnings than Relay Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Relay Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Relay Therapeutics$15.35M281.24-$276.48M-$1.57N/A
Lexicon Pharmaceuticals$49.80M19.48-$50.34M-$0.15N/A

97.0% of Relay Therapeutics shares are held by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. 5.0% of Relay Therapeutics shares are held by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Relay Therapeutics has a beta of 1.69, suggesting that its share price is 69% more volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, suggesting that its share price is 8% more volatile than the broader market.

Relay Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Lexicon Pharmaceuticals' return on equity of -37.53% beat Relay Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Relay TherapeuticsN/A -42.27% -38.67%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Summary

Relay Therapeutics beats Lexicon Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Parabilis Medicines?

Parabilis Medicines (NASDAQ:PBLS) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, risk, media sentiment, earnings, institutional ownership, valuation, dividends and profitability.

In the previous week, Parabilis Medicines had 2 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 4 mentions for Parabilis Medicines and 2 mentions for Lexicon Pharmaceuticals. Lexicon Pharmaceuticals' average media sentiment score of 0.37 beat Parabilis Medicines' score of 0.01 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Parabilis Medicines
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lexicon Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Parabilis Medicines has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Parabilis Medicines' return on equity of 0.00% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Parabilis MedicinesN/A N/A N/A
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Parabilis Medicines currently has a consensus price target of $41.67, suggesting a potential upside of 5.27%. Lexicon Pharmaceuticals has a consensus price target of $4.55, suggesting a potential upside of 108.72%. Given Lexicon Pharmaceuticals' higher possible upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Parabilis Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Parabilis Medicines
0 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
3.00
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Parabilis Medicines has higher earnings, but lower revenue than Lexicon Pharmaceuticals.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Parabilis MedicinesN/AN/AN/AN/AN/A
Lexicon Pharmaceuticals$49.80M19.48-$50.34M-$0.15N/A

Summary

Parabilis Medicines beats Lexicon Pharmaceuticals on 7 of the 12 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Viking Therapeutics?

Viking Therapeutics (NASDAQ:VKTX) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, media sentiment, analyst recommendations, dividends, profitability, valuation, risk and earnings.

76.0% of Viking Therapeutics shares are held by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. 5.3% of Viking Therapeutics shares are held by company insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

In the previous week, Viking Therapeutics had 7 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 9 mentions for Viking Therapeutics and 2 mentions for Lexicon Pharmaceuticals. Viking Therapeutics' average media sentiment score of 0.90 beat Lexicon Pharmaceuticals' score of 0.37 indicating that Viking Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viking Therapeutics
3 Very Positive mention(s)
3 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lexicon Pharmaceuticals has higher revenue and earnings than Viking Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Viking Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viking TherapeuticsN/AN/A-$359.64M-$4.66N/A
Lexicon Pharmaceuticals$49.80M19.48-$50.34M-$0.15N/A

Viking Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Lexicon Pharmaceuticals' return on equity of -37.53% beat Viking Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viking TherapeuticsN/A -94.56% -82.75%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Viking Therapeutics currently has a consensus price target of $96.63, suggesting a potential upside of 181.21%. Lexicon Pharmaceuticals has a consensus price target of $4.55, suggesting a potential upside of 108.72%. Given Viking Therapeutics' stronger consensus rating and higher possible upside, equities research analysts clearly believe Viking Therapeutics is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viking Therapeutics
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

Viking Therapeutics has a beta of 0.69, meaning that its share price is 31% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, meaning that its share price is 8% more volatile than the broader market.

Summary

Viking Therapeutics beats Lexicon Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Denali Therapeutics?

Denali Therapeutics (NASDAQ:DNLI) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, dividends, analyst recommendations, profitability, risk, media sentiment, earnings and valuation.

Lexicon Pharmaceuticals has lower revenue, but higher earnings than Denali Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M12.07-$512.54M-$2.84N/A
Lexicon Pharmaceuticals$49.80M19.48-$50.34M-$0.15N/A

Denali Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Lexicon Pharmaceuticals' return on equity of -37.53% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -55.27% -44.24%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

92.9% of Denali Therapeutics shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 9.7% of Denali Therapeutics shares are owned by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Denali Therapeutics presently has a consensus target price of $35.92, indicating a potential upside of 43.95%. Lexicon Pharmaceuticals has a consensus target price of $4.55, indicating a potential upside of 108.72%. Given Lexicon Pharmaceuticals' higher possible upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Denali Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

In the previous week, Denali Therapeutics had 4 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 6 mentions for Denali Therapeutics and 2 mentions for Lexicon Pharmaceuticals. Denali Therapeutics' average media sentiment score of 0.94 beat Lexicon Pharmaceuticals' score of 0.37 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Denali Therapeutics has a beta of 1.01, meaning that its stock price is 1% more volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, meaning that its stock price is 8% more volatile than the broader market.

Summary

Denali Therapeutics and Lexicon Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Tango Therapeutics?

Tango Therapeutics (NASDAQ:TNGX) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their media sentiment, profitability, dividends, risk, earnings, institutional ownership, analyst recommendations and valuation.

Tango Therapeutics currently has a consensus target price of $43.46, indicating a potential upside of 84.86%. Lexicon Pharmaceuticals has a consensus target price of $4.55, indicating a potential upside of 108.72%. Given Lexicon Pharmaceuticals' higher probable upside, analysts clearly believe Lexicon Pharmaceuticals is more favorable than Tango Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tango Therapeutics
1 Sell rating(s)
2 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.75
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25

79.0% of Tango Therapeutics shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 6.5% of Tango Therapeutics shares are owned by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

In the previous week, Tango Therapeutics had 17 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 19 mentions for Tango Therapeutics and 2 mentions for Lexicon Pharmaceuticals. Tango Therapeutics' average media sentiment score of 0.93 beat Lexicon Pharmaceuticals' score of 0.37 indicating that Tango Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Tango Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lexicon Pharmaceuticals has lower revenue, but higher earnings than Tango Therapeutics. Tango Therapeutics is trading at a lower price-to-earnings ratio than Lexicon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tango Therapeutics$62.38M63.55-$101.59M-$0.85N/A
Lexicon Pharmaceuticals$49.80M19.48-$50.34M-$0.15N/A

Tango Therapeutics has a beta of 1.16, indicating that its stock price is 16% more volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, indicating that its stock price is 8% more volatile than the broader market.

Tango Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Tango Therapeutics' return on equity of -25.75% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Tango TherapeuticsN/A -25.75% -23.36%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Summary

Tango Therapeutics beats Lexicon Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LXRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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LXRX vs. The Competition

MetricLexicon PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.07B$4.07B$7.37B$12.86B
Dividend YieldN/A3.64%2.53%10.69%
P/E Ratio-14.5311.53268.4324.05
Price / Sales19.481,311.61610.3488.11
Price / CashN/A103.9278.1353.57
Price / Book5.5917.0913.076.15
Net Income-$50.34M-$12.52M$3.46B$347.39M
7 Day Performance-6.84%2.74%1.43%-0.64%
1 Month Performance-6.44%6.15%4.58%2.12%
1 Year Performance92.92%60.36%27.60%20.16%

Lexicon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LXRX
Lexicon Pharmaceuticals
1.4325 of 5 stars
$2.18
-9.5%
$4.55
+108.7%
+107.8%$1.07B$49.80MN/A140
RLAY
Relay Therapeutics
3.3224 of 5 stars
$19.94
+0.9%
$25.58
+28.3%
+510.0%$4.33B$15.35MN/A330
PBLS
Parabilis Medicines
2.1129 of 5 stars
$35.73
+2.1%
$41.67
+16.6%
N/A$4.13BN/AN/AN/A
VKTX
Viking Therapeutics
3.363 of 5 stars
$34.44
+0.5%
$97.88
+184.2%
+47.7%$4.00BN/AN/A20
DNLI
Denali Therapeutics
3.1257 of 5 stars
$25.00
+0.7%
$35.92
+43.7%
+73.5%$3.94B$330.53MN/A430

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This page (NASDAQ:LXRX) was last updated on 8/20/2026 by MarketBeat.com Staff.
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