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Lexicon Pharmaceuticals (LXRX) Competitors

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$1.82 0.00 (0.00%)
Closing price 04:00 PM Eastern
Extended Trading
$1.84 +0.01 (+0.82%)
As of 07:30 PM Eastern
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LXRX vs. ELVN, AMLX, GRAL, LEGN, and VKTX

Should you buy Lexicon Pharmaceuticals stock or one of its competitors? Lexicon Pharmaceuticals's main competitors and comparable companies include Enliven Therapeutics (ELVN), Amylyx Pharmaceuticals (AMLX), GRAIL (GRAL), Legend Biotech (LEGN), and Viking Therapeutics (VKTX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Lexicon Pharmaceuticals compare to Enliven Therapeutics?

Enliven Therapeutics (NASDAQ:ELVN) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, analyst recommendations, institutional ownership, risk, media sentiment, profitability, earnings and valuation.

Enliven Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Enliven Therapeutics' return on equity of -18.55% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Enliven TherapeuticsN/A -18.55% -18.09%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Lexicon Pharmaceuticals has higher revenue and earnings than Enliven Therapeutics. Enliven Therapeutics is trading at a lower price-to-earnings ratio than Lexicon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Enliven TherapeuticsN/AN/A-$103.69M-$1.67N/A
Lexicon Pharmaceuticals$49.80M16.13-$50.34M-$0.15N/A

Enliven Therapeutics currently has a consensus price target of $74.44, indicating a potential upside of 59.41%. Lexicon Pharmaceuticals has a consensus price target of $5.70, indicating a potential upside of 215.79%. Given Lexicon Pharmaceuticals' higher possible upside, analysts clearly believe Lexicon Pharmaceuticals is more favorable than Enliven Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Enliven Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

95.1% of Enliven Therapeutics shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 3.0% of Enliven Therapeutics shares are owned by company insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Lexicon Pharmaceuticals had 15 more articles in the media than Enliven Therapeutics. MarketBeat recorded 19 mentions for Lexicon Pharmaceuticals and 4 mentions for Enliven Therapeutics. Enliven Therapeutics' average media sentiment score of 1.12 beat Lexicon Pharmaceuticals' score of 0.34 indicating that Enliven Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Enliven Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
4 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Enliven Therapeutics has a beta of 0.24, meaning that its share price is 76% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, meaning that its share price is 8% more volatile than the broader market.

Summary

Lexicon Pharmaceuticals beats Enliven Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Amylyx Pharmaceuticals?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Amylyx Pharmaceuticals (NASDAQ:AMLX) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, valuation, dividends, institutional ownership, risk, earnings, analyst recommendations and media sentiment.

74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. Comparatively, 95.8% of Amylyx Pharmaceuticals shares are held by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are held by insiders. Comparatively, 10.9% of Amylyx Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Lexicon Pharmaceuticals' return on equity of -37.53% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-147.38% -37.53% -24.96%
Amylyx Pharmaceuticals N/A -52.92%-48.53%

Lexicon Pharmaceuticals presently has a consensus price target of $5.70, indicating a potential upside of 215.79%. Amylyx Pharmaceuticals has a consensus price target of $38.86, indicating a potential upside of 38.15%. Given Lexicon Pharmaceuticals' higher probable upside, equities analysts clearly believe Lexicon Pharmaceuticals is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
3.00

Lexicon Pharmaceuticals has a beta of 1.08, meaning that its share price is 8% more volatile than the broader market. Comparatively, Amylyx Pharmaceuticals has a beta of -0.1, meaning that its share price is 110% less volatile than the broader market.

Lexicon Pharmaceuticals has higher earnings, but lower revenue than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than Lexicon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M16.13-$50.34M-$0.15N/A
Amylyx Pharmaceuticals$87.37M35.87-$144.74M-$1.43N/A

In the previous week, Lexicon Pharmaceuticals had 15 more articles in the media than Amylyx Pharmaceuticals. MarketBeat recorded 19 mentions for Lexicon Pharmaceuticals and 4 mentions for Amylyx Pharmaceuticals. Amylyx Pharmaceuticals' average media sentiment score of 0.99 beat Lexicon Pharmaceuticals' score of 0.34 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
4 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Amylyx Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Lexicon Pharmaceuticals beats Amylyx Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to GRAIL?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and GRAIL (NASDAQ:GRAL) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, analyst recommendations, risk, earnings, profitability, institutional ownership, media sentiment and valuation.

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Comparatively, 1.8% of GRAIL shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Lexicon Pharmaceuticals has a net margin of -147.38% compared to GRAIL's net margin of -236.95%. GRAIL's return on equity of -15.88% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-147.38% -37.53% -24.96%
GRAIL -236.95%-15.88%-14.02%

Lexicon Pharmaceuticals has a beta of 1.08, suggesting that its share price is 8% more volatile than the broader market. Comparatively, GRAIL has a beta of 2.81, suggesting that its share price is 181% more volatile than the broader market.

Lexicon Pharmaceuticals presently has a consensus price target of $5.70, indicating a potential upside of 215.79%. GRAIL has a consensus price target of $93.60, indicating a potential downside of 32.71%. Given Lexicon Pharmaceuticals' stronger consensus rating and higher possible upside, research analysts plainly believe Lexicon Pharmaceuticals is more favorable than GRAIL.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
GRAIL
1 Sell rating(s)
6 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.33

Lexicon Pharmaceuticals has higher earnings, but lower revenue than GRAIL. GRAIL is trading at a lower price-to-earnings ratio than Lexicon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M16.13-$50.34M-$0.15N/A
GRAIL$147.17M42.22-$408.35M-$9.75N/A

In the previous week, Lexicon Pharmaceuticals had 9 more articles in the media than GRAIL. MarketBeat recorded 19 mentions for Lexicon Pharmaceuticals and 10 mentions for GRAIL. GRAIL's average media sentiment score of 0.60 beat Lexicon Pharmaceuticals' score of 0.34 indicating that GRAIL is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
4 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
GRAIL
3 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Lexicon Pharmaceuticals beats GRAIL on 9 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Legend Biotech?

Legend Biotech (NASDAQ:LEGN) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, dividends, valuation, profitability, earnings, institutional ownership and media sentiment.

Legend Biotech currently has a consensus price target of $55.79, indicating a potential upside of 196.91%. Lexicon Pharmaceuticals has a consensus price target of $5.70, indicating a potential upside of 215.79%. Given Lexicon Pharmaceuticals' higher probable upside, analysts clearly believe Lexicon Pharmaceuticals is more favorable than Legend Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Legend Biotech
1 Sell rating(s)
5 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.53
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

70.9% of Legend Biotech shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 0.0% of Legend Biotech shares are owned by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Legend Biotech has a beta of 0.57, suggesting that its stock price is 43% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, suggesting that its stock price is 8% more volatile than the broader market.

Lexicon Pharmaceuticals has lower revenue, but higher earnings than Legend Biotech. Legend Biotech is trading at a lower price-to-earnings ratio than Lexicon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Legend Biotech$1.03B3.54-$296.80M-$0.25N/A
Lexicon Pharmaceuticals$49.80M16.13-$50.34M-$0.15N/A

Legend Biotech has a net margin of -7.21% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Legend Biotech's return on equity of -8.71% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Legend Biotech-7.21% -8.71% -5.40%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

In the previous week, Lexicon Pharmaceuticals had 12 more articles in the media than Legend Biotech. MarketBeat recorded 19 mentions for Lexicon Pharmaceuticals and 7 mentions for Legend Biotech. Lexicon Pharmaceuticals' average media sentiment score of 0.34 beat Legend Biotech's score of 0.33 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Legend Biotech
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lexicon Pharmaceuticals
4 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Lexicon Pharmaceuticals beats Legend Biotech on 10 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Viking Therapeutics?

Viking Therapeutics (NASDAQ:VKTX) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their earnings, risk, valuation, profitability, dividends, analyst recommendations, media sentiment and institutional ownership.

In the previous week, Viking Therapeutics had 2 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 21 mentions for Viking Therapeutics and 19 mentions for Lexicon Pharmaceuticals. Viking Therapeutics' average media sentiment score of 0.60 beat Lexicon Pharmaceuticals' score of 0.34 indicating that Viking Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viking Therapeutics
10 Very Positive mention(s)
2 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Lexicon Pharmaceuticals
4 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

76.0% of Viking Therapeutics shares are owned by institutional investors. Comparatively, 74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 5.3% of Viking Therapeutics shares are owned by company insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Lexicon Pharmaceuticals has higher revenue and earnings than Viking Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Viking Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viking TherapeuticsN/AN/A-$359.64M-$4.66N/A
Lexicon Pharmaceuticals$49.80M16.13-$50.34M-$0.15N/A

Viking Therapeutics has a beta of 0.66, suggesting that its share price is 34% less volatile than the broader market. Comparatively, Lexicon Pharmaceuticals has a beta of 1.08, suggesting that its share price is 8% more volatile than the broader market.

Viking Therapeutics currently has a consensus target price of $99.67, suggesting a potential upside of 230.57%. Lexicon Pharmaceuticals has a consensus target price of $5.70, suggesting a potential upside of 215.79%. Given Viking Therapeutics' stronger consensus rating and higher possible upside, research analysts clearly believe Viking Therapeutics is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viking Therapeutics
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75
Lexicon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Viking Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -147.38%. Lexicon Pharmaceuticals' return on equity of -37.53% beat Viking Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viking TherapeuticsN/A -94.56% -82.75%
Lexicon Pharmaceuticals -147.38%-37.53%-24.96%

Summary

Viking Therapeutics beats Lexicon Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LXRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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LXRX vs. The Competition

MetricLexicon PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$809.82M$3.87B$7.14B$13.10B
Dividend YieldN/A3.65%2.54%16.76%
P/E Ratio-12.137.65214.4921.54
Price / Sales16.261,292.25607.7591.81
Price / CashN/A122.6077.6051.75
Price / Book6.0716.6310.926.30
Net Income-$50.34M-$22.67M$3.50B$361.43M
7 Day Performance1.39%-3.05%-2.11%-1.67%
1 Month Performance-18.75%-10.75%-6.34%-3.94%
1 Year Performance31.88%21.11%8.81%2.77%

Lexicon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LXRX
Lexicon Pharmaceuticals
1.9258 of 5 stars
$1.82
flat
$5.70
+213.2%
+29.1%$809.82M$49.80MN/A81
ELVN
Enliven Therapeutics
2.873 of 5 stars
$48.87
-1.2%
$75.00
+53.5%
+133.0%$3.62BN/AN/A67
AMLX
Amylyx Pharmaceuticals
3.5892 of 5 stars
$32.39
-0.1%
$38.86
+20.0%
+100.6%$3.61B$87.37MN/A136
GRAL
GRAIL
1.0473 of 5 stars
$107.97
+33.7%
$70.30
-34.9%
+113.6%$3.61B$147.17MN/A910
LEGN
Legend Biotech
3.5538 of 5 stars
$18.53
+5.2%
$53.14
+186.8%
-40.8%$3.41B$1.03BN/A2,965

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This page (NASDAQ:LXRX) was last updated on 10/2/2026 by MarketBeat.com Staff.
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