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Ironwood Pharmaceuticals (IRWD) Competitors

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$4.13 -0.16 (-3.73%)
Closing price 08/24/2026 04:00 PM Eastern
Extended Trading
$4.16 +0.04 (+0.85%)
As of 08/24/2026 06:42 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

IRWD vs. ABBV, ZLAB, NRIX, BEAM, and SLS

Should you buy Ironwood Pharmaceuticals stock or one of its competitors? Ironwood Pharmaceuticals's main competitors and comparable companies include AbbVie (ABBV), Zai Lab (ZLAB), Nurix Therapeutics (NRIX), Beam Therapeutics (BEAM), and SELLAS Life Sciences Group (SLS). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Ironwood Pharmaceuticals compare to AbbVie?

Ironwood Pharmaceuticals (NASDAQ:IRWD) and AbbVie (NYSE:ABBV) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their risk, analyst recommendations, media sentiment, earnings, profitability, institutional ownership, dividends and valuation.

Ironwood Pharmaceuticals has a beta of 0.2, indicating that its share price is 80% less volatile than the broader market. Comparatively, AbbVie has a beta of 0.3, indicating that its share price is 70% less volatile than the broader market.

70.2% of AbbVie shares are owned by institutional investors. 9.3% of Ironwood Pharmaceuticals shares are owned by insiders. Comparatively, 0.1% of AbbVie shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

AbbVie has higher revenue and earnings than Ironwood Pharmaceuticals. Ironwood Pharmaceuticals is trading at a lower price-to-earnings ratio than AbbVie, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ironwood Pharmaceuticals$296.15M2.30$24.02M$0.775.36
AbbVie$61.16B7.64$4.23B$3.5474.75

Ironwood Pharmaceuticals currently has a consensus price target of $6.23, indicating a potential upside of 50.93%. AbbVie has a consensus price target of $275.95, indicating a potential upside of 4.29%. Given Ironwood Pharmaceuticals' higher probable upside, research analysts clearly believe Ironwood Pharmaceuticals is more favorable than AbbVie.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ironwood Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.57
AbbVie
0 Sell rating(s)
5 Hold rating(s)
19 Buy rating(s)
2 Strong Buy rating(s)
2.88

Ironwood Pharmaceuticals has a net margin of 33.36% compared to AbbVie's net margin of 9.80%. Ironwood Pharmaceuticals' return on equity of -58.38% beat AbbVie's return on equity.

Company Net Margins Return on Equity Return on Assets
Ironwood Pharmaceuticals33.36% -58.38% 34.93%
AbbVie 9.80%-422.07%14.34%

In the previous week, AbbVie had 51 more articles in the media than Ironwood Pharmaceuticals. MarketBeat recorded 54 mentions for AbbVie and 3 mentions for Ironwood Pharmaceuticals. AbbVie's average media sentiment score of 1.08 beat Ironwood Pharmaceuticals' score of 0.54 indicating that AbbVie is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ironwood Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
AbbVie
35 Very Positive mention(s)
4 Positive mention(s)
10 Neutral mention(s)
0 Negative mention(s)
4 Very Negative mention(s)
Positive

Summary

AbbVie beats Ironwood Pharmaceuticals on 12 of the 17 factors compared between the two stocks.

How does Ironwood Pharmaceuticals compare to Zai Lab?

Ironwood Pharmaceuticals (NASDAQ:IRWD) and Zai Lab (NASDAQ:ZLAB) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, profitability, earnings, institutional ownership, media sentiment, valuation and risk.

Ironwood Pharmaceuticals presently has a consensus target price of $6.23, indicating a potential upside of 50.93%. Zai Lab has a consensus target price of $37.25, indicating a potential upside of 45.28%. Given Ironwood Pharmaceuticals' higher probable upside, equities research analysts plainly believe Ironwood Pharmaceuticals is more favorable than Zai Lab.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ironwood Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.57
Zai Lab
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.71

Ironwood Pharmaceuticals has a beta of 0.2, suggesting that its share price is 80% less volatile than the broader market. Comparatively, Zai Lab has a beta of 0.78, suggesting that its share price is 22% less volatile than the broader market.

Ironwood Pharmaceuticals has higher earnings, but lower revenue than Zai Lab. Zai Lab is trading at a lower price-to-earnings ratio than Ironwood Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ironwood Pharmaceuticals$296.15M2.30$24.02M$0.775.36
Zai Lab$460.16M6.34-$175.54M-$1.71N/A

41.7% of Zai Lab shares are held by institutional investors. 9.3% of Ironwood Pharmaceuticals shares are held by insiders. Comparatively, 4.9% of Zai Lab shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Ironwood Pharmaceuticals had 1 more articles in the media than Zai Lab. MarketBeat recorded 3 mentions for Ironwood Pharmaceuticals and 2 mentions for Zai Lab. Zai Lab's average media sentiment score of 0.74 beat Ironwood Pharmaceuticals' score of 0.54 indicating that Zai Lab is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ironwood Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zai Lab
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ironwood Pharmaceuticals has a net margin of 33.36% compared to Zai Lab's net margin of -41.86%. Zai Lab's return on equity of -27.43% beat Ironwood Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ironwood Pharmaceuticals33.36% -58.38% 34.93%
Zai Lab -41.86%-27.43%-16.72%

Summary

Ironwood Pharmaceuticals and Zai Lab tied by winning 8 of the 16 factors compared between the two stocks.

How does Ironwood Pharmaceuticals compare to Nurix Therapeutics?

Nurix Therapeutics (NASDAQ:NRIX) and Ironwood Pharmaceuticals (NASDAQ:IRWD) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their profitability, valuation, analyst recommendations, dividends, media sentiment, institutional ownership, risk and earnings.

Nurix Therapeutics presently has a consensus price target of $34.21, suggesting a potential upside of 30.24%. Ironwood Pharmaceuticals has a consensus price target of $6.23, suggesting a potential upside of 50.93%. Given Ironwood Pharmaceuticals' higher probable upside, analysts clearly believe Ironwood Pharmaceuticals is more favorable than Nurix Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Nurix Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.80
Ironwood Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.57

Nurix Therapeutics has a beta of 1.79, indicating that its stock price is 79% more volatile than the broader market. Comparatively, Ironwood Pharmaceuticals has a beta of 0.2, indicating that its stock price is 80% less volatile than the broader market.

In the previous week, Nurix Therapeutics had 3 more articles in the media than Ironwood Pharmaceuticals. MarketBeat recorded 6 mentions for Nurix Therapeutics and 3 mentions for Ironwood Pharmaceuticals. Nurix Therapeutics' average media sentiment score of 1.11 beat Ironwood Pharmaceuticals' score of 0.54 indicating that Nurix Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Nurix Therapeutics
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ironwood Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ironwood Pharmaceuticals has a net margin of 33.36% compared to Nurix Therapeutics' net margin of -928.44%. Ironwood Pharmaceuticals' return on equity of -58.38% beat Nurix Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Nurix Therapeutics-928.44% -76.09% -57.31%
Ironwood Pharmaceuticals 33.36%-58.38%34.93%

Ironwood Pharmaceuticals has higher revenue and earnings than Nurix Therapeutics. Nurix Therapeutics is trading at a lower price-to-earnings ratio than Ironwood Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Nurix Therapeutics$83.98M32.46-$264.46M-$3.45N/A
Ironwood Pharmaceuticals$296.15M2.30$24.02M$0.775.36

Summary

Ironwood Pharmaceuticals beats Nurix Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Ironwood Pharmaceuticals compare to Beam Therapeutics?

Ironwood Pharmaceuticals (NASDAQ:IRWD) and Beam Therapeutics (NASDAQ:BEAM) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their dividends, valuation, profitability, earnings, institutional ownership, analyst recommendations, risk and media sentiment.

Ironwood Pharmaceuticals has a beta of 0.2, suggesting that its share price is 80% less volatile than the broader market. Comparatively, Beam Therapeutics has a beta of 2.23, suggesting that its share price is 123% more volatile than the broader market.

Ironwood Pharmaceuticals has higher revenue and earnings than Beam Therapeutics. Beam Therapeutics is trading at a lower price-to-earnings ratio than Ironwood Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ironwood Pharmaceuticals$296.15M2.30$24.02M$0.775.36
Beam Therapeutics$139.74M20.94-$79.99M-$0.86N/A

99.7% of Beam Therapeutics shares are owned by institutional investors. 9.3% of Ironwood Pharmaceuticals shares are owned by company insiders. Comparatively, 3.8% of Beam Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Ironwood Pharmaceuticals has a net margin of 33.36% compared to Beam Therapeutics' net margin of -54.75%. Beam Therapeutics' return on equity of -30.71% beat Ironwood Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ironwood Pharmaceuticals33.36% -58.38% 34.93%
Beam Therapeutics -54.75%-30.71%-24.07%

Ironwood Pharmaceuticals presently has a consensus price target of $6.23, indicating a potential upside of 50.93%. Beam Therapeutics has a consensus price target of $49.00, indicating a potential upside of 72.96%. Given Beam Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Beam Therapeutics is more favorable than Ironwood Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ironwood Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.57
Beam Therapeutics
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69

In the previous week, Beam Therapeutics had 1 more articles in the media than Ironwood Pharmaceuticals. MarketBeat recorded 4 mentions for Beam Therapeutics and 3 mentions for Ironwood Pharmaceuticals. Beam Therapeutics' average media sentiment score of 1.16 beat Ironwood Pharmaceuticals' score of 0.54 indicating that Beam Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ironwood Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Beam Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Beam Therapeutics beats Ironwood Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Ironwood Pharmaceuticals compare to SELLAS Life Sciences Group?

SELLAS Life Sciences Group (NASDAQ:SLS) and Ironwood Pharmaceuticals (NASDAQ:IRWD) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their dividends, media sentiment, institutional ownership, profitability, earnings, analyst recommendations, valuation and risk.

SELLAS Life Sciences Group has a beta of 2.48, indicating that its stock price is 148% more volatile than the broader market. Comparatively, Ironwood Pharmaceuticals has a beta of 0.2, indicating that its stock price is 80% less volatile than the broader market.

SELLAS Life Sciences Group currently has a consensus target price of $10.00, suggesting a potential downside of 30.17%. Ironwood Pharmaceuticals has a consensus target price of $6.23, suggesting a potential upside of 50.93%. Given Ironwood Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Ironwood Pharmaceuticals is more favorable than SELLAS Life Sciences Group.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SELLAS Life Sciences Group
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Ironwood Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.57

Ironwood Pharmaceuticals has higher revenue and earnings than SELLAS Life Sciences Group. SELLAS Life Sciences Group is trading at a lower price-to-earnings ratio than Ironwood Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SELLAS Life Sciences GroupN/AN/A-$26.86M-$0.21N/A
Ironwood Pharmaceuticals$296.15M2.30$24.02M$0.775.36

In the previous week, SELLAS Life Sciences Group had 7 more articles in the media than Ironwood Pharmaceuticals. MarketBeat recorded 10 mentions for SELLAS Life Sciences Group and 3 mentions for Ironwood Pharmaceuticals. SELLAS Life Sciences Group's average media sentiment score of 0.60 beat Ironwood Pharmaceuticals' score of 0.54 indicating that SELLAS Life Sciences Group is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SELLAS Life Sciences Group
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Ironwood Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

17.4% of SELLAS Life Sciences Group shares are owned by institutional investors. 1.3% of SELLAS Life Sciences Group shares are owned by insiders. Comparatively, 9.3% of Ironwood Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Ironwood Pharmaceuticals has a net margin of 33.36% compared to SELLAS Life Sciences Group's net margin of 0.00%. SELLAS Life Sciences Group's return on equity of -35.91% beat Ironwood Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
SELLAS Life Sciences GroupN/A -35.91% -33.34%
Ironwood Pharmaceuticals 33.36%-58.38%34.93%

Summary

Ironwood Pharmaceuticals beats SELLAS Life Sciences Group on 10 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding IRWD and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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IRWD vs. The Competition

MetricIronwood PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$708.88M$4.01B$7.36B$12.81B
Dividend YieldN/A3.64%2.54%10.78%
P/E Ratio5.3611.69270.5624.05
Price / Sales2.301,415.32639.68105.23
Price / Cash16.6744.9429.0336.89
Price / Book-2.5717.2611.186.40
Net Income$24.02M-$22.72M$3.46B$347.95M
7 Day Performance-4.18%2.51%1.73%1.49%
1 Month Performance11.32%9.80%7.33%5.15%
1 Year Performance225.20%57.43%26.11%17.01%

Ironwood Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
IRWD
Ironwood Pharmaceuticals
2.6917 of 5 stars
$4.13
-3.7%
$6.23
+50.9%
+225.2%$708.88M$296.15M5.36220
ABBV
AbbVie
4.6539 of 5 stars
$256.18
+2.3%
$275.73
+7.6%
+25.8%$450.22B$61.16B71.9857,000
ZLAB
Zai Lab
2.3963 of 5 stars
$25.19
-1.8%
$40.20
+59.6%
-26.8%$2.84B$460.16MN/A1,784
NRIX
Nurix Therapeutics
3.1193 of 5 stars
$26.93
-0.9%
$34.21
+27.0%
+159.1%$2.80B$36.77MN/A300
BEAM
Beam Therapeutics
2.1458 of 5 stars
$26.64
-1.7%
$49.00
+83.9%
+70.3%$2.74B$156.04MN/A510

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This page (NASDAQ:IRWD) was last updated on 8/25/2026 by MarketBeat.com Staff.
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