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Vanda Pharmaceuticals (VNDA) Competitors

Vanda Pharmaceuticals logo
$6.00 -0.24 (-3.85%)
Closing price 07/13/2026 04:00 PM Eastern
Extended Trading
$6.06 +0.07 (+1.08%)
As of 04:30 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

VNDA vs. MNKD, OPK, LXRX, GERN, and RIGL

Should you buy Vanda Pharmaceuticals stock or one of its competitors? MarketBeat compares Vanda Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Vanda Pharmaceuticals include MannKind (MNKD), OPKO Health (OPK), Lexicon Pharmaceuticals (LXRX), Geron (GERN), and Rigel Pharmaceuticals (RIGL). These companies are all part of the "biotechnology" industry.

How does Vanda Pharmaceuticals compare to MannKind?

MannKind (NASDAQ:MNKD) and Vanda Pharmaceuticals (NASDAQ:VNDA) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their dividends, profitability, institutional ownership, earnings, media sentiment, valuation, risk and analyst recommendations.

MannKind has a net margin of -6.63% compared to Vanda Pharmaceuticals' net margin of -109.99%. MannKind's return on equity of -11.21% beat Vanda Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
MannKind-6.63% -11.21% -3.92%
Vanda Pharmaceuticals -109.99%-32.26%-23.43%

MannKind has higher revenue and earnings than Vanda Pharmaceuticals. MannKind is trading at a lower price-to-earnings ratio than Vanda Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
MannKind$348.97M3.58$5.86M-$0.07N/A
Vanda Pharmaceuticals$216.10M1.67-$220.47M-$4.05N/A

MannKind has a beta of 1.09, indicating that its share price is 9% more volatile than the broader market. Comparatively, Vanda Pharmaceuticals has a beta of 0.6, indicating that its share price is 40% less volatile than the broader market.

MannKind currently has a consensus price target of $8.97, suggesting a potential upside of 122.00%. Vanda Pharmaceuticals has a consensus price target of $14.30, suggesting a potential upside of 138.33%. Given Vanda Pharmaceuticals' higher possible upside, analysts clearly believe Vanda Pharmaceuticals is more favorable than MannKind.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MannKind
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.50
Vanda Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

49.6% of MannKind shares are held by institutional investors. Comparatively, 88.1% of Vanda Pharmaceuticals shares are held by institutional investors. 2.6% of MannKind shares are held by insiders. Comparatively, 10.7% of Vanda Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

In the previous week, Vanda Pharmaceuticals had 1 more articles in the media than MannKind. MarketBeat recorded 6 mentions for Vanda Pharmaceuticals and 5 mentions for MannKind. Vanda Pharmaceuticals' average media sentiment score of 0.74 beat MannKind's score of 0.55 indicating that Vanda Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
MannKind
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vanda Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

MannKind beats Vanda Pharmaceuticals on 9 of the 15 factors compared between the two stocks.

How does Vanda Pharmaceuticals compare to OPKO Health?

OPKO Health (NASDAQ:OPK) and Vanda Pharmaceuticals (NASDAQ:VNDA) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, dividends, risk, institutional ownership, valuation, profitability, media sentiment and analyst recommendations.

In the previous week, Vanda Pharmaceuticals had 1 more articles in the media than OPKO Health. MarketBeat recorded 6 mentions for Vanda Pharmaceuticals and 5 mentions for OPKO Health. Vanda Pharmaceuticals' average media sentiment score of 0.74 beat OPKO Health's score of -0.03 indicating that Vanda Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
OPKO Health
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Vanda Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

OPKO Health has a beta of 1.48, suggesting that its stock price is 48% more volatile than the broader market. Comparatively, Vanda Pharmaceuticals has a beta of 0.6, suggesting that its stock price is 40% less volatile than the broader market.

Vanda Pharmaceuticals has lower revenue, but higher earnings than OPKO Health. OPKO Health is trading at a lower price-to-earnings ratio than Vanda Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
OPKO Health$606.90M1.53-$225.68M-$0.27N/A
Vanda Pharmaceuticals$216.10M1.67-$220.47M-$4.05N/A

OPKO Health has a net margin of -36.63% compared to Vanda Pharmaceuticals' net margin of -109.99%. OPKO Health's return on equity of -16.78% beat Vanda Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
OPKO Health-36.63% -16.78% -10.98%
Vanda Pharmaceuticals -109.99%-32.26%-23.43%

OPKO Health currently has a consensus target price of $1.55, suggesting a potential upside of 26.02%. Vanda Pharmaceuticals has a consensus target price of $14.30, suggesting a potential upside of 138.33%. Given Vanda Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Vanda Pharmaceuticals is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.80
Vanda Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

64.6% of OPKO Health shares are owned by institutional investors. Comparatively, 88.1% of Vanda Pharmaceuticals shares are owned by institutional investors. 44.7% of OPKO Health shares are owned by company insiders. Comparatively, 10.7% of Vanda Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Summary

Vanda Pharmaceuticals beats OPKO Health on 9 of the 16 factors compared between the two stocks.

How does Vanda Pharmaceuticals compare to Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Vanda Pharmaceuticals (NASDAQ:VNDA) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, media sentiment, risk, institutional ownership, profitability, analyst recommendations, valuation and dividends.

Lexicon Pharmaceuticals has a beta of 1.05, suggesting that its stock price is 5% more volatile than the broader market. Comparatively, Vanda Pharmaceuticals has a beta of 0.6, suggesting that its stock price is 40% less volatile than the broader market.

Lexicon Pharmaceuticals has a net margin of -37.46% compared to Vanda Pharmaceuticals' net margin of -109.99%. Lexicon Pharmaceuticals' return on equity of -18.64% beat Vanda Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-37.46% -18.64% -11.79%
Vanda Pharmaceuticals -109.99%-32.26%-23.43%

Lexicon Pharmaceuticals has higher earnings, but lower revenue than Vanda Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Vanda Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M19.36-$50.34M-$0.07N/A
Vanda Pharmaceuticals$216.10M1.67-$220.47M-$4.05N/A

In the previous week, Vanda Pharmaceuticals had 4 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 6 mentions for Vanda Pharmaceuticals and 2 mentions for Lexicon Pharmaceuticals. Lexicon Pharmaceuticals' average media sentiment score of 1.28 beat Vanda Pharmaceuticals' score of 0.74 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vanda Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. Comparatively, 88.1% of Vanda Pharmaceuticals shares are owned by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Comparatively, 10.7% of Vanda Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Lexicon Pharmaceuticals currently has a consensus price target of $4.55, suggesting a potential upside of 109.68%. Vanda Pharmaceuticals has a consensus price target of $14.30, suggesting a potential upside of 138.33%. Given Vanda Pharmaceuticals' higher probable upside, analysts plainly believe Vanda Pharmaceuticals is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75
Vanda Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

Summary

Lexicon Pharmaceuticals beats Vanda Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Vanda Pharmaceuticals compare to Geron?

Geron (NASDAQ:GERN) and Vanda Pharmaceuticals (NASDAQ:VNDA) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, valuation, profitability, dividends, earnings, media sentiment and risk.

In the previous week, Vanda Pharmaceuticals had 1 more articles in the media than Geron. MarketBeat recorded 6 mentions for Vanda Pharmaceuticals and 5 mentions for Geron. Geron's average media sentiment score of 0.75 beat Vanda Pharmaceuticals' score of 0.74 indicating that Geron is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Geron
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vanda Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Geron has a beta of 0.6, meaning that its stock price is 40% less volatile than the broader market. Comparatively, Vanda Pharmaceuticals has a beta of 0.6, meaning that its stock price is 40% less volatile than the broader market.

Geron has higher earnings, but lower revenue than Vanda Pharmaceuticals. Geron is trading at a lower price-to-earnings ratio than Vanda Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Geron$196.12M4.65-$83.50M-$0.11N/A
Vanda Pharmaceuticals$216.10M1.67-$220.47M-$4.05N/A

Geron has a net margin of -35.48% compared to Vanda Pharmaceuticals' net margin of -109.99%. Geron's return on equity of -23.31% beat Vanda Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Geron-35.48% -23.31% -10.08%
Vanda Pharmaceuticals -109.99%-32.26%-23.43%

Geron presently has a consensus target price of $4.00, suggesting a potential upside of 181.69%. Vanda Pharmaceuticals has a consensus target price of $14.30, suggesting a potential upside of 138.33%. Given Geron's higher possible upside, equities analysts plainly believe Geron is more favorable than Vanda Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Geron
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.20
Vanda Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

73.7% of Geron shares are held by institutional investors. Comparatively, 88.1% of Vanda Pharmaceuticals shares are held by institutional investors. 1.7% of Geron shares are held by company insiders. Comparatively, 10.7% of Vanda Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Summary

Geron beats Vanda Pharmaceuticals on 8 of the 15 factors compared between the two stocks.

How does Vanda Pharmaceuticals compare to Rigel Pharmaceuticals?

Rigel Pharmaceuticals (NASDAQ:RIGL) and Vanda Pharmaceuticals (NASDAQ:VNDA) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, risk, dividends, profitability, media sentiment and analyst recommendations.

Rigel Pharmaceuticals has a beta of 1.14, indicating that its share price is 14% more volatile than the broader market. Comparatively, Vanda Pharmaceuticals has a beta of 0.6, indicating that its share price is 40% less volatile than the broader market.

In the previous week, Vanda Pharmaceuticals had 3 more articles in the media than Rigel Pharmaceuticals. MarketBeat recorded 6 mentions for Vanda Pharmaceuticals and 3 mentions for Rigel Pharmaceuticals. Vanda Pharmaceuticals' average media sentiment score of 0.74 beat Rigel Pharmaceuticals' score of 0.62 indicating that Vanda Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rigel Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vanda Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

66.2% of Rigel Pharmaceuticals shares are owned by institutional investors. Comparatively, 88.1% of Vanda Pharmaceuticals shares are owned by institutional investors. 10.5% of Rigel Pharmaceuticals shares are owned by company insiders. Comparatively, 10.7% of Vanda Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Rigel Pharmaceuticals presently has a consensus price target of $54.50, suggesting a potential upside of 31.96%. Vanda Pharmaceuticals has a consensus price target of $14.30, suggesting a potential upside of 138.33%. Given Vanda Pharmaceuticals' stronger consensus rating and higher possible upside, analysts plainly believe Vanda Pharmaceuticals is more favorable than Rigel Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rigel Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Vanda Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

Rigel Pharmaceuticals has higher revenue and earnings than Vanda Pharmaceuticals. Vanda Pharmaceuticals is trading at a lower price-to-earnings ratio than Rigel Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rigel Pharmaceuticals$294.28M2.60$367.02M$18.722.21
Vanda Pharmaceuticals$216.10M1.67-$220.47M-$4.05N/A

Rigel Pharmaceuticals has a net margin of 121.50% compared to Vanda Pharmaceuticals' net margin of -109.99%. Rigel Pharmaceuticals' return on equity of 47.99% beat Vanda Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rigel Pharmaceuticals121.50% 47.99% 32.40%
Vanda Pharmaceuticals -109.99%-32.26%-23.43%

Summary

Rigel Pharmaceuticals beats Vanda Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding VNDA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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VNDA vs. The Competition

MetricVanda PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$375.24M$3.71B$7.05B$12.61B
Dividend YieldN/A2.20%2.68%8.00%
P/E Ratio-1.4820.8527.1124.26
Price / Sales1.67314.01589.14117.88
Price / CashN/A61.9829.2249.36
Price / Book1.088.4910.756.29
Net Income-$220.47M$23.83M$3.58B$330.66M
7 Day Performance-6.10%-3.56%-2.10%-1.35%
1 Month Performance2.21%6.31%3.29%-0.64%
1 Year Performance20.72%48.30%26.32%19.08%

Vanda Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
VNDA
Vanda Pharmaceuticals
2.3647 of 5 stars
$6.00
-3.8%
$14.30
+138.3%
+26.6%$375.24M$216.10MN/A290
MNKD
MannKind
3.5999 of 5 stars
$4.27
-5.5%
$8.97
+110.0%
+7.2%$1.32B$348.97MN/A400
OPK
OPKO Health
2.1042 of 5 stars
$1.50
-1.3%
$1.55
+3.3%
-8.9%$1.13B$606.90MN/A1,373
LXRX
Lexicon Pharmaceuticals
2.2265 of 5 stars
$2.32
flat
$4.55
+96.1%
+100.9%$1.03B$69.64MN/A140
GERN
Geron
1.8249 of 5 stars
$1.44
+5.9%
$2.50
+73.6%
+7.6%$923.79M$183.88MN/A70

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This page (NASDAQ:VNDA) was last updated on 7/14/2026 by MarketBeat.com Staff.
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