Leap Therapeutics (LPTX) Competitors $0.34 +0.02 (+4.82%) Closing price 08/13/2025 04:00 PM EasternExtended Trading$0.33 -0.01 (-2.95%) As of 04:35 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock LPTX vs. DTIL, UNCY, PDSB, ELYM, KLRS, ANVS, PYRGF, PRLD, CVM, and INKTShould you be buying Leap Therapeutics stock or one of its competitors? The main competitors of Leap Therapeutics include Precision BioSciences (DTIL), Unicycive Therapeutics (UNCY), PDS Biotechnology (PDSB), Eliem Therapeutics (ELYM), Kalaris Therapeutics (KLRS), Annovis Bio (ANVS), PyroGenesis Canada (PYRGF), Prelude Therapeutics (PRLD), CEL-SCI (CVM), and MiNK Therapeutics (INKT). These companies are all part of the "pharmaceutical products" industry. Leap Therapeutics vs. Its Competitors Precision BioSciences Unicycive Therapeutics PDS Biotechnology Eliem Therapeutics Kalaris Therapeutics Annovis Bio PyroGenesis Canada Prelude Therapeutics CEL-SCI MiNK Therapeutics Precision BioSciences (NASDAQ:DTIL) and Leap Therapeutics (NASDAQ:LPTX) are both small-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, analyst recommendations, media sentiment, risk, earnings, valuation, institutional ownership and dividends. Which has more risk & volatility, DTIL or LPTX? Precision BioSciences has a beta of 1.52, suggesting that its stock price is 52% more volatile than the S&P 500. Comparatively, Leap Therapeutics has a beta of -0.27, suggesting that its stock price is 127% less volatile than the S&P 500. Which has stronger valuation & earnings, DTIL or LPTX? Precision BioSciences has higher revenue and earnings than Leap Therapeutics. Precision BioSciences is trading at a lower price-to-earnings ratio than Leap Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioPrecision BioSciences$68.70M0.80$7.17M-$8.81-0.53Leap TherapeuticsN/AN/A-$67.56M-$1.70-0.20 Do analysts rate DTIL or LPTX? Precision BioSciences currently has a consensus price target of $47.00, indicating a potential upside of 902.13%. Leap Therapeutics has a consensus price target of $3.38, indicating a potential upside of 895.58%. Given Precision BioSciences' stronger consensus rating and higher possible upside, equities analysts plainly believe Precision BioSciences is more favorable than Leap Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Precision BioSciences 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 3.00Leap Therapeutics 0 Sell rating(s) 3 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 2.00 Does the media prefer DTIL or LPTX? In the previous week, Precision BioSciences had 3 more articles in the media than Leap Therapeutics. MarketBeat recorded 5 mentions for Precision BioSciences and 2 mentions for Leap Therapeutics. Leap Therapeutics' average media sentiment score of 0.93 beat Precision BioSciences' score of -0.09 indicating that Leap Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Precision BioSciences 0 Very Positive mention(s) 2 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Leap Therapeutics 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do institutionals & insiders believe in DTIL or LPTX? 38.0% of Precision BioSciences shares are held by institutional investors. Comparatively, 30.5% of Leap Therapeutics shares are held by institutional investors. 4.5% of Precision BioSciences shares are held by insiders. Comparatively, 7.5% of Leap Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term. Is DTIL or LPTX more profitable? Leap Therapeutics has a net margin of 0.00% compared to Precision BioSciences' net margin of -6,205.79%. Leap Therapeutics' return on equity of -162.15% beat Precision BioSciences' return on equity.Company Net Margins Return on Equity Return on Assets Precision BioSciences-6,205.79% -176.47% -69.05% Leap Therapeutics N/A -162.15%-120.05% SummaryPrecision BioSciences beats Leap Therapeutics on 9 of the 15 factors compared between the two stocks. Get Leap Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for LPTX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding LPTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart LPTX vs. The Competition Export to ExcelMetricLeap TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$13.40M$3.03B$5.54B$9.82BDividend YieldN/A2.27%4.62%4.11%P/E Ratio-0.2020.6730.1526.03Price / SalesN/A363.56461.34104.73Price / CashN/A42.0537.7558.93Price / Book0.377.638.496.06Net Income-$67.56M-$54.65M$3.26B$265.11M7 Day Performance7.35%5.41%4.19%3.38%1 Month Performance2.70%7.14%4.64%2.28%1 Year Performance-86.22%31.27%35.15%29.67% Leap Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)LPTXLeap Therapeutics2.553 of 5 stars$0.34+4.8%$3.38+895.6%-86.9%$13.40MN/A-0.2040DTILPrecision BioSciences4.2662 of 5 stars$4.35-0.7%$47.00+980.5%-47.6%$51.63M$68.70M-0.49200Earnings ReportUNCYUnicycive Therapeutics2.6064 of 5 stars$4.01-2.0%$60.00+1,396.3%+86.9%$51.70M$680K-0.799PDSBPDS Biotechnology2.0137 of 5 stars$1.08-2.7%$9.00+733.3%-62.0%$50.74MN/A-1.1520News CoverageGap UpELYMEliem TherapeuticsN/A$1.70+1.2%N/A-74.1%$50.58MN/A-3.219KLRSKalaris Therapeutics2.0751 of 5 stars$2.66-0.4%$3.00+12.8%N/A$49.94MN/A0.00110News CoverageEarnings ReportANVSAnnovis Bio1.8741 of 5 stars$2.82+10.6%$18.00+538.3%-66.1%$49.69MN/A-1.313Earnings ReportGap UpPYRGFPyroGenesis CanadaN/A$0.26-5.4%N/A-53.6%$49.68M$9.14M-4.4290Gap DownPRLDPrelude Therapeutics3.3548 of 5 stars$0.83-3.6%$4.50+444.1%-85.4%$48.42M$7M-0.49120Gap DownCVMCEL-SCI0.2535 of 5 stars$7.03-5.5%N/A-76.3%$48.38MN/A-14.6543News CoverageINKTMiNK Therapeutics2.1761 of 5 stars$12.22+1.3%$37.50+206.9%+106.2%$48.07MN/A-4.8530 Related Companies and Tools Related Companies Precision BioSciences Alternatives Unicycive Therapeutics Alternatives PDS Biotechnology Alternatives Eliem Therapeutics Alternatives Kalaris Therapeutics Alternatives Annovis Bio Alternatives PyroGenesis Canada Alternatives Prelude Therapeutics Alternatives CEL-SCI Alternatives MiNK Therapeutics Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:LPTX) was last updated on 8/14/2025 by MarketBeat.com Staff From Our PartnersHIDDEN IN THE BOOK OF GENESIS…“This land I will give to you…” — a 4,000-year-old line from Genesis may hold the key to unlocking a $150 tril...Paradigm Press | SponsoredGet This Stock NowThis company is the lifeblood of AI data centers, yet almost no one has caught up with the story. 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