Leap Therapeutics (LPTX) Competitors $0.42 +0.03 (+7.95%) As of 04/30/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock LPTX vs. IOBT, ARTV, PMVP, ASRT, ADVM, KRON, IKNA, MDCX, DTIL, and BYSIShould you be buying Leap Therapeutics stock or one of its competitors? The main competitors of Leap Therapeutics include IO Biotech (IOBT), Artiva Biotherapeutics (ARTV), PMV Pharmaceuticals (PMVP), Assertio (ASRT), Adverum Biotechnologies (ADVM), Kronos Bio (KRON), Ikena Oncology (IKNA), Medicus Pharma (MDCX), Precision BioSciences (DTIL), and BeyondSpring (BYSI). These companies are all part of the "pharmaceutical products" industry. Leap Therapeutics vs. IO Biotech Artiva Biotherapeutics PMV Pharmaceuticals Assertio Adverum Biotechnologies Kronos Bio Ikena Oncology Medicus Pharma Precision BioSciences BeyondSpring Leap Therapeutics (NASDAQ:LPTX) and IO Biotech (NASDAQ:IOBT) are both small-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, profitability, risk, media sentiment, community ranking, valuation, earnings, institutional ownership and dividends. Which has more volatility and risk, LPTX or IOBT? Leap Therapeutics has a beta of 0.22, meaning that its stock price is 78% less volatile than the S&P 500. Comparatively, IO Biotech has a beta of 0.08, meaning that its stock price is 92% less volatile than the S&P 500. Does the media refer more to LPTX or IOBT? In the previous week, IO Biotech had 4 more articles in the media than Leap Therapeutics. MarketBeat recorded 6 mentions for IO Biotech and 2 mentions for Leap Therapeutics. Leap Therapeutics' average media sentiment score of 0.93 beat IO Biotech's score of 0.91 indicating that Leap Therapeutics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Leap Therapeutics 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive IO Biotech 1 Very Positive mention(s) 2 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is LPTX or IOBT more profitable? IO Biotech's return on equity of -86.56% beat Leap Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Leap TherapeuticsN/A -116.24% -93.18% IO Biotech N/A -86.56%-75.24% Do institutionals and insiders believe in LPTX or IOBT? 30.5% of Leap Therapeutics shares are held by institutional investors. Comparatively, 54.8% of IO Biotech shares are held by institutional investors. 5.4% of Leap Therapeutics shares are held by insiders. Comparatively, 2.3% of IO Biotech shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth. Do analysts rate LPTX or IOBT? Leap Therapeutics presently has a consensus price target of $4.92, indicating a potential upside of 1,075.95%. IO Biotech has a consensus price target of $9.33, indicating a potential upside of 862.20%. Given Leap Therapeutics' higher probable upside, equities research analysts plainly believe Leap Therapeutics is more favorable than IO Biotech.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Leap Therapeutics 0 Sell rating(s) 3 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 2.25IO Biotech 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 1 Strong Buy rating(s) 3.33 Which has better valuation & earnings, LPTX or IOBT? IO Biotech is trading at a lower price-to-earnings ratio than Leap Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioLeap TherapeuticsN/AN/A-$81.41M-$1.84-0.23IO BiotechN/AN/A-$86.08M-$1.37-0.71 Does the MarketBeat Community believe in LPTX or IOBT? Leap Therapeutics received 269 more outperform votes than IO Biotech when rated by MarketBeat users. However, 92.59% of users gave IO Biotech an outperform vote while only 68.37% of users gave Leap Therapeutics an outperform vote. CompanyUnderperformOutperformLeap TherapeuticsOutperform Votes29468.37% Underperform Votes13631.63% IO BiotechOutperform Votes2592.59% Underperform Votes27.41% SummaryIO Biotech beats Leap Therapeutics on 9 of the 16 factors compared between the two stocks. Get Leap Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for LPTX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart LPTX vs. The Competition Export to ExcelMetricLeap TherapeuticsPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$17.25M$6.90B$5.57B$7.82BDividend YieldN/A3.06%5.11%4.22%P/E Ratio-0.227.4522.4218.48Price / SalesN/A242.72394.10103.91Price / CashN/A65.8538.1834.62Price / Book0.186.516.774.25Net Income-$81.41M$143.21M$3.22B$248.23M7 Day Performance5.85%3.97%3.26%3.29%1 Month Performance32.06%0.37%0.02%2.42%1 Year Performance-86.51%2.60%18.01%5.54% Leap Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)LPTXLeap Therapeutics2.4498 of 5 stars$0.42+8.0%$4.92+1,076.0%-86.5%$17.25MN/A-0.2240Gap UpIOBTIO Biotech3.3543 of 5 stars$0.89+3.4%$9.33+949.4%-33.6%$58.60MN/A-0.6530Gap DownARTVArtiva BiotherapeuticsN/A$2.40+7.1%$20.40+750.0%N/A$58.47M$251,000.000.0081High Trading VolumePMVPPMV Pharmaceuticals2.2647 of 5 stars$1.10+7.8%$5.67+415.2%-45.0%$57.13MN/A-1.1050Upcoming EarningsASRTAssertio1.8953 of 5 stars$0.59-2.6%$2.75+362.6%-26.6%$56.94M$124.96M-0.8120Upcoming EarningsNews CoverageADVMAdverum Biotechnologies4.1005 of 5 stars$2.73-6.8%$25.83+846.3%-66.5%$56.79M$1M-0.46190KRONKronos Bio2.8443 of 5 stars$0.91+1.9%$1.63+79.6%-13.3%$55.18M$9.85M-0.63100Upcoming EarningsPositive NewsIKNAIkena Oncology2.7431 of 5 stars$1.14+2.7%$3.00+163.2%-3.8%$55.01M$659,000.00-0.9370Positive NewsMDCXMedicus PharmaN/A$4.06+1.5%$12.00+195.6%N/A$54.47MN/A0.00N/AAnalyst ForecastNews CoverageGap UpDTILPrecision BioSciences4.2753 of 5 stars$5.13+2.2%$37.67+634.2%-45.8%$54.12M$68.70M85.51200Positive NewsBYSIBeyondSpringN/A$1.34+2.3%N/A-13.4%$54.02M$1.88M0.0080Positive NewsGap Up Related Companies and Tools Related Companies IO Biotech Alternatives Artiva Biotherapeutics Alternatives PMV Pharmaceuticals Alternatives Assertio Alternatives Adverum Biotechnologies Alternatives Kronos Bio Alternatives Ikena Oncology Alternatives Medicus Pharma Alternatives Precision BioSciences Alternatives BeyondSpring Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:LPTX) was last updated on 5/1/2025 by MarketBeat.com Staff From Our PartnersHow to invest in Elon Musk’s Optimus before its launchElon Musk is set to completely take over the AI industry with Optimus… A breakthrough AI-powered robot that El...InvestorPlace | SponsoredIs he more powerful than Trump? 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