NASDAQ:OPK OPKO Health (OPK) Stock Price, News & Analysis $1.61 +0.04 (+2.55%) Closing price 09/16/2026 04:00 PM EasternExtended Trading$1.63 +0.02 (+1.24%) As of 08:33 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About OPKO Health Stock (NASDAQ:OPK) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get OPKO Health alerts:Sign Up Key Stats Today's Range$1.58▼$1.6550-Day Range$1.17▼$1.6952-Week Range$0.98▼$1.73Volume2.29 million shsAverage Volume2.87 million shsMarket Capitalization$1.20 billionP/E RatioN/ADividend YieldN/APrice Target$1.55Consensus RatingHold Company Overview OPKO Health, Inc. is a healthcare company focused on diagnostics and pharmaceuticals. Its diagnostics business includes BioReference Laboratories, which provides clinical laboratory testing and specialty diagnostic services in the United States, and the 4Kscore test, a blood-based test designed to help assess the risk of aggressive prostate cancer. OPKO’s pharmaceutical activities include products and development programs in areas such as endocrinology, nephrology, and other specialty-care markets. Its marketed products include Rayaldee, an extended-release calcifediol formulation used to treat secondary hyperparathyroidism in adults with chronic kidney disease and vitamin D insufficiency. The company has also developed long-acting growth-hormone technologies and works with commercial partners to advance and distribute certain products internationally. Founded in 1991, OPKO Health is headquartered in Miami, Florida. The company serves patients and healthcare providers primarily in the United States, with additional international reach through subsidiaries, licensing arrangements, and other strategic partnerships. Phillip Frost has served as the company’s chairman and chief executive officer.AI Generated. May Contain Errors. Read More OPKO Health Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks16th Percentile Overall ScoreOPK MarketRank™: OPKO Health scored higher than 16% of companies evaluated by MarketBeat, and ranked 851st out of 903 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion1.4 / 5Analyst RatingHold Consensus RatingOPKO Health has received a consensus rating of Hold. The company's average rating score is 2.00, and is based on no strong buy ratings, 1 buy rating, 3 hold ratings, and 1 sell rating.Upside/DownsideThe consensus price target for OPKO Health is close to its current price, suggesting limited near-term upside or downside.Amount of Analyst CoverageOPKO Health has only been the subject of 2 research reports in the past 90 days.Read more about OPKO Health's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for OPKO Health are expected to decrease in the coming year, from ($0.23) to ($0.28) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of OPKO Health is -17.89, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of OPKO Health is -17.89, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioOPKO Health has a P/B Ratio of 0.96. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about OPKO Health's valuation and earnings. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted8.38% of the float of OPKO Health has been sold short.Short Interest Ratio / Days to CoverOPKO Health has a short interest ratio ("days to cover") of 13.77, which indicates bearish sentiment.Change versus previous monthShort interest in OPKO Health has recently increased by 2.70%, indicating that investor sentiment is decreasing. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldOPKO Health does not currently pay a dividend.Dividend GrowthOPKO Health does not have a long track record of dividend growth. News and Social Media3.7 / 5News Sentiment0.97 News SentimentOPKO Health has a news sentiment score of 0.97. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.79 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 6 news articles for OPKO Health this week, compared to 4 articles on an average week.Search InterestOnly 6 people have searched for OPK on MarketBeat in the last 30 days. This is a decrease of -14% compared to the previous 30 days.MarketBeat Follows4 people have added OPKO Health to their MarketBeat watchlist in the last 30 days. This is an increase of 100% compared to the previous 30 days. Company Ownership1.4 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, OPKO Health insiders have not sold or bought any company stock.Percentage Held by Insiders44.72% of the stock of OPKO Health is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions64.63% of the stock of OPKO Health is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about OPKO Health's insider trading history. Receive OPK Stock News and Ratings via Email Sign-up to receive the latest news and ratings for OPKO Health and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. OPK Stock News HeadlinesThe Bull Case For OPKO Health (OPK) Could Change Following New Mazdutide Royalty-Backed Financing StrategySeptember 15 at 11:55 PM | finance.yahoo.comOPKO Health (OPK) Cashes In A Future Royalty Stream EarlySeptember 13, 2026 | finance.yahoo.comThe REAL Reason Trump is Invading IranFor a moment… Forget about Trump’s ties to Israel. Forget about reports of Iran’s nuclear program. Because my research has led me to believe we’re risking World War 3 with Iran for a completely different reason.September 17 at 1:00 AM | Banyan Hill Publishing (Ad)OPKO Health (OPK) Cashes In A Future Royalty Stream EarlySeptember 13, 2026 | insidermonkey.comOPKO Health op Wells Fargo-conferentie: cashrijke verschuiving naar therapeuticaSeptember 10, 2026 | nl.investing.comOPKO Health, Inc. (OPK)September 9, 2026 | finance.yahoo.comOPKO Health to Participate in the Wells Fargo 21st Annual Healthcare ConferenceSeptember 8, 2026 | finance.yahoo.comOPKO Health to Participate in the Wells Fargo 21st Annual Healthcare ConferenceSeptember 8, 2026 | globenewswire.comSee More Headlines OPK Stock Analysis - Frequently Asked Questions How have OPK shares performed this year? OPKO Health's stock was trading at $1.26 at the beginning of 2026. Since then, OPK stock has increased by 27.8% and is now trading at $1.61. How were OPKO Health's earnings last quarter? OPKO Health, Inc. (NASDAQ:OPK) posted its quarterly earnings results on Monday, July, 27th. The biotechnology company reported ($0.01) earnings per share for the quarter, beating analysts' consensus estimates of ($0.08) by $0.07. OPKO Health's revenue for the quarter was up 4.3% compared to the same quarter last year. Read the conference call transcript. Who are OPKO Health's major shareholders? OPKO Health's top institutional investors include BlackRock Inc. (4.95%), AWM Investment Company Inc. (0.28%), Bank of New York Mellon Corp (0.18%) and California State Teachers Retirement System (0.13%). Insiders that own company stock include Phillip Md Et Al Frost, Jane Ph D Hsiao, Steven D Rubin, Opko Health, Inc, John A Paganelli, Gary J Nabel, Richard C Pfenniger Jr and Richard M Krasno. View institutional ownership trends. How do I buy shares of OPKO Health? Shares of OPK stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of OPKO Health own? Based on aggregate information from My MarketBeat watchlists, some other companies that OPKO Health investors own include Humana (HUM), Voyager Therapeutics (VYGR), American Water Works (AWK), Waste Connections (WCN), DiamondRock Hospitality (DRH) and AUO (AUOTY). Company Calendar Last Earnings7/27/2026Today9/17/2026Next Earnings (Estimated)11/04/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (1m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 OPK's financial health is in the Green zone, according to TradeSmith. OPK has been in this zone for over one month. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Healthcare Providers & Services Sub-IndustryHealthcare Services Current SymbolNASDAQ:OPK CIK944809 Webwww.opko.com Phone(305) 575-4100Fax305-575-6015Employees1,373Year Founded2007Price Target and Rating Average Price Target for OPKO Health$1.55 High Price Target$1.60 Low Price Target$1.50 Potential Upside/Downside-3.7%Consensus RatingHold Rating Score (0-4)2.00 Research Coverage5 Analysts Profitability EPS (Trailing Twelve Months)($0.09) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$225.68 million Net Margins-12.40% Pretax Margin-13.58% Return on Equity-5.88% Return on Assets-3.83% Debt Debt-to-Equity Ratio0.28 Current Ratio3.35 Quick Ratio2.93 Sales & Book Value Annual Sales$606.90 million Price / Sales1.98 Cash FlowN/A Price / Cash FlowN/A Book Value$1.67 per share Price / Book0.96Miscellaneous Outstanding Shares746,330,000Free Float412,570,000Market Cap$1.20 billion OptionableOptionable Beta1.50 Social Links The Best Nuclear Energy Stocks to BuyNuclear energy is entering a new growth cycle as rising power demand, expanding data centers, and renewed policy support bring the sector back into focus. 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