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Pacific Biosciences of California (PACB) Competitors

Pacific Biosciences of California logo
$1.35 -0.02 (-1.46%)
Closing price 06/11/2026 04:00 PM Eastern
Extended Trading
$1.38 +0.03 (+2.22%)
As of 06/11/2026 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PACB vs. TXG, HBIO, LMNX, TMO, and A

Should you buy Pacific Biosciences of California stock or one of its competitors? MarketBeat compares Pacific Biosciences of California with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Pacific Biosciences of California include 10x Genomics (TXG), Harvard Bioscience (HBIO), Defiance Daily Target 2X Long LMND ETF (LMNX), Thermo Fisher Scientific (TMO), and Agilent Technologies (A).

How does Pacific Biosciences of California compare to 10x Genomics?

Pacific Biosciences of California (NASDAQ:PACB) and 10x Genomics (NASDAQ:TXG) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, earnings, analyst recommendations, dividends, valuation, institutional ownership, profitability and risk.

10x Genomics has a net margin of -3.55% compared to Pacific Biosciences of California's net margin of -80.35%. 10x Genomics' return on equity of -2.86% beat Pacific Biosciences of California's return on equity.

Company Net Margins Return on Equity Return on Assets
Pacific Biosciences of California-80.35% -571.06% -18.82%
10x Genomics -3.55%-2.86%-2.23%

10x Genomics has higher revenue and earnings than Pacific Biosciences of California. 10x Genomics is trading at a lower price-to-earnings ratio than Pacific Biosciences of California, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pacific Biosciences of California$160.01M2.62-$546.38M-$0.43N/A
10x Genomics$642.82M5.74-$43.54M-$0.17N/A

Pacific Biosciences of California has a beta of 2.35, meaning that its share price is 135% more volatile than the broader market. Comparatively, 10x Genomics has a beta of 2.12, meaning that its share price is 112% more volatile than the broader market.

In the previous week, 10x Genomics had 8 more articles in the media than Pacific Biosciences of California. MarketBeat recorded 10 mentions for 10x Genomics and 2 mentions for Pacific Biosciences of California. Pacific Biosciences of California's average media sentiment score of 0.93 beat 10x Genomics' score of 0.81 indicating that Pacific Biosciences of California is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pacific Biosciences of California
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
10x Genomics
3 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

84.7% of 10x Genomics shares are held by institutional investors. 3.7% of Pacific Biosciences of California shares are held by company insiders. Comparatively, 8.8% of 10x Genomics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Pacific Biosciences of California currently has a consensus target price of $1.83, indicating a potential upside of 35.80%. 10x Genomics has a consensus target price of $23.17, indicating a potential downside of 20.25%. Given Pacific Biosciences of California's higher probable upside, analysts plainly believe Pacific Biosciences of California is more favorable than 10x Genomics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pacific Biosciences of California
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80
10x Genomics
1 Sell rating(s)
10 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.20

Summary

10x Genomics beats Pacific Biosciences of California on 12 of the 16 factors compared between the two stocks.

How does Pacific Biosciences of California compare to Harvard Bioscience?

Pacific Biosciences of California (NASDAQ:PACB) and Harvard Bioscience (NASDAQ:HBIO) are both small-cap life sciences tools & services companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, earnings, analyst recommendations, dividends, valuation, institutional ownership, profitability and risk.

In the previous week, Pacific Biosciences of California and Pacific Biosciences of California both had 2 articles in the media. Harvard Bioscience's average media sentiment score of 0.94 beat Pacific Biosciences of California's score of 0.93 indicating that Harvard Bioscience is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pacific Biosciences of California
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Harvard Bioscience
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Pacific Biosciences of California has a beta of 2.35, meaning that its share price is 135% more volatile than the broader market. Comparatively, Harvard Bioscience has a beta of 1.53, meaning that its share price is 53% more volatile than the broader market.

Pacific Biosciences of California currently has a consensus target price of $1.83, indicating a potential upside of 35.80%. Harvard Bioscience has a consensus target price of $6.00, indicating a potential downside of 9.64%. Given Pacific Biosciences of California's higher probable upside, analysts plainly believe Pacific Biosciences of California is more favorable than Harvard Bioscience.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pacific Biosciences of California
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80
Harvard Bioscience
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Harvard Bioscience has lower revenue, but higher earnings than Pacific Biosciences of California. Pacific Biosciences of California is trading at a lower price-to-earnings ratio than Harvard Bioscience, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pacific Biosciences of California$160.01M2.62-$546.38M-$0.43N/A
Harvard Bioscience$86.55M0.35-$56.70M-$2.17N/A

80.9% of Harvard Bioscience shares are held by institutional investors. 3.7% of Pacific Biosciences of California shares are held by company insiders. Comparatively, 20.3% of Harvard Bioscience shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Harvard Bioscience has a net margin of -11.44% compared to Pacific Biosciences of California's net margin of -80.35%. Harvard Bioscience's return on equity of -25.78% beat Pacific Biosciences of California's return on equity.

Company Net Margins Return on Equity Return on Assets
Pacific Biosciences of California-80.35% -571.06% -18.82%
Harvard Bioscience -11.44%-25.78%-4.37%

Summary

Harvard Bioscience beats Pacific Biosciences of California on 9 of the 14 factors compared between the two stocks.

How does Pacific Biosciences of California compare to Defiance Daily Target 2X Long LMND ETF?

Defiance Daily Target 2X Long LMND ETF (NASDAQ:LMNX) and Pacific Biosciences of California (NASDAQ:PACB) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their valuation, earnings, institutional ownership, profitability, dividends, risk, analyst recommendations and media sentiment.

Defiance Daily Target 2X Long LMND ETF has a net margin of 5.39% compared to Pacific Biosciences of California's net margin of -80.35%. Defiance Daily Target 2X Long LMND ETF's return on equity of 4.66% beat Pacific Biosciences of California's return on equity.

Company Net Margins Return on Equity Return on Assets
Defiance Daily Target 2X Long LMND ETF5.39% 4.66% 2.91%
Pacific Biosciences of California -80.35%-571.06%-18.82%

87.8% of Defiance Daily Target 2X Long LMND ETF shares are held by institutional investors. 6.6% of Defiance Daily Target 2X Long LMND ETF shares are held by insiders. Comparatively, 3.7% of Pacific Biosciences of California shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Pacific Biosciences of California has a consensus price target of $1.83, suggesting a potential upside of 35.80%. Given Pacific Biosciences of California's stronger consensus rating and higher possible upside, analysts clearly believe Pacific Biosciences of California is more favorable than Defiance Daily Target 2X Long LMND ETF.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Defiance Daily Target 2X Long LMND ETF
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
Pacific Biosciences of California
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80

In the previous week, Pacific Biosciences of California had 1 more articles in the media than Defiance Daily Target 2X Long LMND ETF. MarketBeat recorded 2 mentions for Pacific Biosciences of California and 1 mentions for Defiance Daily Target 2X Long LMND ETF. Defiance Daily Target 2X Long LMND ETF's average media sentiment score of 1.87 beat Pacific Biosciences of California's score of 0.93 indicating that Defiance Daily Target 2X Long LMND ETF is being referred to more favorably in the media.

Company Overall Sentiment
Defiance Daily Target 2X Long LMND ETF Very Positive
Pacific Biosciences of California Positive

Defiance Daily Target 2X Long LMND ETF has a beta of -10.21, meaning that its stock price is 1,121% less volatile than the broader market. Comparatively, Pacific Biosciences of California has a beta of 2.35, meaning that its stock price is 135% more volatile than the broader market.

Defiance Daily Target 2X Long LMND ETF has higher revenue and earnings than Pacific Biosciences of California. Pacific Biosciences of California is trading at a lower price-to-earnings ratio than Defiance Daily Target 2X Long LMND ETF, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Defiance Daily Target 2X Long LMND ETF$437.66M0.01$15.17M$0.5125.63
Pacific Biosciences of California$160.01M2.62-$546.38M-$0.43N/A

Summary

Defiance Daily Target 2X Long LMND ETF beats Pacific Biosciences of California on 10 of the 16 factors compared between the two stocks.

How does Pacific Biosciences of California compare to Thermo Fisher Scientific?

Pacific Biosciences of California (NASDAQ:PACB) and Thermo Fisher Scientific (NYSE:TMO) are both medical companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, valuation, profitability, media sentiment, risk, dividends, earnings and institutional ownership.

Thermo Fisher Scientific has a net margin of 15.15% compared to Pacific Biosciences of California's net margin of -80.35%. Thermo Fisher Scientific's return on equity of 16.86% beat Pacific Biosciences of California's return on equity.

Company Net Margins Return on Equity Return on Assets
Pacific Biosciences of California-80.35% -571.06% -18.82%
Thermo Fisher Scientific 15.15%16.86%8.15%

89.2% of Thermo Fisher Scientific shares are held by institutional investors. 3.7% of Pacific Biosciences of California shares are held by insiders. Comparatively, 0.3% of Thermo Fisher Scientific shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Pacific Biosciences of California has a beta of 2.35, indicating that its share price is 135% more volatile than the broader market. Comparatively, Thermo Fisher Scientific has a beta of 0.88, indicating that its share price is 12% less volatile than the broader market.

In the previous week, Thermo Fisher Scientific had 39 more articles in the media than Pacific Biosciences of California. MarketBeat recorded 41 mentions for Thermo Fisher Scientific and 2 mentions for Pacific Biosciences of California. Thermo Fisher Scientific's average media sentiment score of 1.39 beat Pacific Biosciences of California's score of 0.93 indicating that Thermo Fisher Scientific is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pacific Biosciences of California
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Thermo Fisher Scientific
37 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
1 Very Negative mention(s)
Positive

Thermo Fisher Scientific has higher revenue and earnings than Pacific Biosciences of California. Pacific Biosciences of California is trading at a lower price-to-earnings ratio than Thermo Fisher Scientific, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pacific Biosciences of California$160.01M2.62-$546.38M-$0.43N/A
Thermo Fisher Scientific$44.56B3.96$6.70B$18.1926.12

Pacific Biosciences of California presently has a consensus target price of $1.83, indicating a potential upside of 35.80%. Thermo Fisher Scientific has a consensus target price of $608.95, indicating a potential upside of 28.17%. Given Pacific Biosciences of California's higher probable upside, equities research analysts clearly believe Pacific Biosciences of California is more favorable than Thermo Fisher Scientific.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pacific Biosciences of California
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80
Thermo Fisher Scientific
0 Sell rating(s)
5 Hold rating(s)
18 Buy rating(s)
2 Strong Buy rating(s)
2.88

Summary

Thermo Fisher Scientific beats Pacific Biosciences of California on 14 of the 17 factors compared between the two stocks.

How does Pacific Biosciences of California compare to Agilent Technologies?

Pacific Biosciences of California (NASDAQ:PACB) and Agilent Technologies (NYSE:A) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, media sentiment, dividends, valuation, risk, profitability, earnings and analyst recommendations.

Agilent Technologies has higher revenue and earnings than Pacific Biosciences of California. Pacific Biosciences of California is trading at a lower price-to-earnings ratio than Agilent Technologies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Pacific Biosciences of California$160.01M2.62-$546.38M-$0.43N/A
Agilent Technologies$6.95B5.26$1.30B$4.9825.98

Pacific Biosciences of California has a beta of 2.35, suggesting that its share price is 135% more volatile than the broader market. Comparatively, Agilent Technologies has a beta of 1.26, suggesting that its share price is 26% more volatile than the broader market.

Pacific Biosciences of California presently has a consensus price target of $1.83, suggesting a potential upside of 35.80%. Agilent Technologies has a consensus price target of $160.93, suggesting a potential upside of 24.40%. Given Pacific Biosciences of California's higher probable upside, equities research analysts plainly believe Pacific Biosciences of California is more favorable than Agilent Technologies.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pacific Biosciences of California
2 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.80
Agilent Technologies
0 Sell rating(s)
3 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.88

Agilent Technologies has a net margin of 19.55% compared to Pacific Biosciences of California's net margin of -80.35%. Agilent Technologies' return on equity of 24.33% beat Pacific Biosciences of California's return on equity.

Company Net Margins Return on Equity Return on Assets
Pacific Biosciences of California-80.35% -571.06% -18.82%
Agilent Technologies 19.55%24.33%12.99%

In the previous week, Agilent Technologies had 17 more articles in the media than Pacific Biosciences of California. MarketBeat recorded 19 mentions for Agilent Technologies and 2 mentions for Pacific Biosciences of California. Agilent Technologies' average media sentiment score of 1.10 beat Pacific Biosciences of California's score of 0.93 indicating that Agilent Technologies is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pacific Biosciences of California
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Agilent Technologies
15 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Agilent Technologies beats Pacific Biosciences of California on 13 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PACB and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PACB vs. The Competition

MetricPacific Biosciences of CaliforniaMED INSTRUMENTS IndustryMedical SectorNASDAQ Exchange
Market Cap$425.52M$7.24B$6.47B$11.73B
Dividend YieldN/A1.21%2.67%5.56%
P/E Ratio-3.1448.1324.4324.35
Price / Sales2.6276.75503.66108.32
Price / Cash1.7425.0143.2054.62
Price / Book67.506.9110.506.82
Net Income-$546.38M$159.22M$3.56B$337.41M
7 Day Performance-6.90%-1.01%0.23%2.29%
1 Month Performance5.47%3.89%0.67%3.48%
1 Year Performance14.41%-0.45%22.17%27.16%

Pacific Biosciences of California Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PACB
Pacific Biosciences of California
2.616 of 5 stars
$1.35
-1.5%
$1.83
+35.8%
+16.4%$425.52M$160.01MN/A730
TXG
10x Genomics
1.9308 of 5 stars
$29.18
-6.0%
$23.17
-20.6%
+169.5%$3.94B$642.82MN/A1,240
HBIO
Harvard Bioscience
2.6071 of 5 stars
$6.01
-3.1%
$6.00
-0.2%
+14.8%$27.94M$86.55MN/A490
LMNX
Defiance Daily Target 2X Long LMND ETF
N/A$11.39
+7.8%
N/AN/A$3.76M$437.66M22.331,325
TMO
Thermo Fisher Scientific
4.8905 of 5 stars
$469.41
-0.7%
$613.67
+30.7%
+14.4%$175.70B$44.56B25.81125,000

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This page (NASDAQ:PACB) was last updated on 6/12/2026 by MarketBeat.com Staff.
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