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PainReform (PRFX) Competitors

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$1.35 +0.08 (+6.30%)
Closing price 10/15/2025 04:00 PM Eastern
Extended Trading
$1.34 -0.02 (-1.11%)
As of 05:44 AM Eastern
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PRFX vs. HOOK, AEON, SNPX, IMCC, PHXM, BFRI, VYNE, ADXN, ERNA, and RNAZ

Should you be buying PainReform stock or one of its competitors? The main competitors of PainReform include HOOKIPA Pharma (HOOK), AEON Biopharma (AEON), Synaptogenix (SNPX), IM Cannabis (IMCC), PHAXIAM Therapeutics (PHXM), Biofrontera (BFRI), VYNE Therapeutics (VYNE), Addex Therapeutics (ADXN), Ernexa Therapeutics (ERNA), and TransCode Therapeutics (RNAZ). These companies are all part of the "pharmaceutical products" industry.

PainReform vs. Its Competitors

HOOKIPA Pharma (NASDAQ:HOOK) and PainReform (NASDAQ:PRFX) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their earnings, analyst recommendations, risk, institutional ownership, media sentiment, valuation, dividends and profitability.

In the previous week, PainReform had 2 more articles in the media than HOOKIPA Pharma. MarketBeat recorded 2 mentions for PainReform and 0 mentions for HOOKIPA Pharma. PainReform's average media sentiment score of 0.95 beat HOOKIPA Pharma's score of 0.00 indicating that PainReform is being referred to more favorably in the news media.

Company Overall Sentiment
HOOKIPA Pharma Neutral
PainReform Positive

63.9% of HOOKIPA Pharma shares are held by institutional investors. Comparatively, 37.3% of PainReform shares are held by institutional investors. 3.3% of HOOKIPA Pharma shares are held by insiders. Comparatively, 34.4% of PainReform shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

PainReform has lower revenue, but higher earnings than HOOKIPA Pharma. HOOKIPA Pharma is trading at a lower price-to-earnings ratio than PainReform, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
HOOKIPA Pharma$9.35M1.16-$43.50M-$4.73-0.19
PainReformN/AN/A-$14.59M-$147.33-0.01

HOOKIPA Pharma has a beta of 1.04, meaning that its stock price is 4% more volatile than the S&P 500. Comparatively, PainReform has a beta of 0.58, meaning that its stock price is 42% less volatile than the S&P 500.

HOOKIPA Pharma presently has a consensus price target of $4.50, suggesting a potential upside of 405.62%. Given HOOKIPA Pharma's stronger consensus rating and higher possible upside, equities analysts clearly believe HOOKIPA Pharma is more favorable than PainReform.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
HOOKIPA Pharma
0 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.33
PainReform
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

PainReform has a net margin of 0.00% compared to HOOKIPA Pharma's net margin of -785.66%. PainReform's return on equity of 0.00% beat HOOKIPA Pharma's return on equity.

Company Net Margins Return on Equity Return on Assets
HOOKIPA Pharma-785.66% -120.09% -77.14%
PainReform N/A N/A N/A

Summary

PainReform beats HOOKIPA Pharma on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRFX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRFX vs. The Competition

MetricPainReformMED IndustryMedical SectorNASDAQ Exchange
Market Cap$2.56M$2.96B$6.11B$10.45B
Dividend YieldN/A57.77%5.73%4.77%
P/E Ratio-0.0122.7985.3627.36
Price / SalesN/A783.65596.99137.58
Price / CashN/A172.6337.4661.86
Price / Book0.655.5112.286.81
Net Income-$14.59M$33.06M$3.32B$276.80M
7 Day Performance-5.59%0.23%0.59%0.42%
1 Month Performance-2.17%14.73%10.54%7.86%
1 Year Performance-51.79%-1.42%70.62%41.24%

PainReform Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRFX
PainReform
1.5454 of 5 stars
$1.35
+6.3%
N/A-40.8%$2.56MN/A-0.014
HOOK
HOOKIPA Pharma
2.892 of 5 stars
$0.90
-0.4%
$4.50
+401.7%
-75.6%$10.93M$9.35M-0.15160Gap Up
AEON
AEON Biopharma
0.9387 of 5 stars
$0.94
+10.0%
N/A-98.5%$10.89MN/A5.205Gap Up
SNPX
Synaptogenix
N/A$7.71
+20.3%
N/A+220.0%$10.72MN/A-0.764Gap Down
IMCC
IM Cannabis
0.6664 of 5 stars
$2.02
-2.4%
N/A-8.0%$10.61M$39.44M-3.74340
PHXM
PHAXIAM Therapeutics
N/A$3.10
flat
N/AN/A$10.58MN/A0.0049
BFRI
Biofrontera
2.2443 of 5 stars
$1.03
-3.3%
$2.75
+168.3%
+27.3%$10.39M$37.32M-0.4570
VYNE
VYNE Therapeutics
3.2398 of 5 stars
$0.41
+12.7%
$6.25
+1,439.4%
-81.1%$10.34M$476K-0.4530High Trading Volume
ADXN
Addex Therapeutics
0.4688 of 5 stars
$9.51
+5.4%
N/A-13.9%$10.08M$55.35K-27.9730News Coverage
Analyst Forecast
Gap Down
ERNA
Ernexa Therapeutics
0.8891 of 5 stars
$1.31
-3.7%
N/A-92.1%$10.05M$580K-0.1610Gap Up
RNAZ
TransCode Therapeutics
2.1871 of 5 stars
$11.94
+1.2%
$280.00
+2,245.3%
-99.9%$9.91MN/A0.009

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This page (NASDAQ:PRFX) was last updated on 10/16/2025 by MarketBeat.com Staff
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