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Biofrontera (BFRI) Competitors

Biofrontera logo
$1.21 -0.06 (-4.72%)
As of 04:00 PM Eastern

BFRI vs. ZYBT, DWTX, RYM, SCLX, and SCYX

Should you buy Biofrontera stock or one of its competitors? Biofrontera's main competitors and comparable companies include Zhengye Biotechnology (ZYBT), Dogwood Therapeutics (DWTX), RYTHM (RYM), Scilex (SCLX), and SCYNEXIS (SCYX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "pharmaceuticals" industry.

How does Biofrontera compare to Zhengye Biotechnology?

Zhengye Biotechnology (NASDAQ:ZYBT) and Biofrontera (NASDAQ:BFRI) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, risk, institutional ownership, valuation, media sentiment, analyst recommendations, dividends and profitability.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zhengye Biotechnology
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Biofrontera
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

10.1% of Biofrontera shares are held by institutional investors. 8.1% of Biofrontera shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Zhengye Biotechnology has a beta of -2.74, meaning that its stock price is 374% less volatile than the broader market. Comparatively, Biofrontera has a beta of 0.78, meaning that its stock price is 22% less volatile than the broader market.

In the previous week, Zhengye Biotechnology had 3 more articles in the media than Biofrontera. MarketBeat recorded 5 mentions for Zhengye Biotechnology and 2 mentions for Biofrontera. Biofrontera's average media sentiment score of 1.00 beat Zhengye Biotechnology's score of 0.29 indicating that Biofrontera is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zhengye Biotechnology
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Biofrontera
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Zhengye Biotechnology has a net margin of 0.00% compared to Biofrontera's net margin of -25.66%. Zhengye Biotechnology's return on equity of 0.00% beat Biofrontera's return on equity.

Company Net Margins Return on Equity Return on Assets
Zhengye BiotechnologyN/A N/A N/A
Biofrontera -25.66%-515.34%-53.91%

Zhengye Biotechnology has higher earnings, but lower revenue than Biofrontera.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zhengye Biotechnology$16.64M5.13-$9.98MN/AN/A
Biofrontera$41.71M0.37-$10.54M-$0.97N/A

Summary

Biofrontera beats Zhengye Biotechnology on 7 of the 13 factors compared between the two stocks.

How does Biofrontera compare to Dogwood Therapeutics?

Biofrontera (NASDAQ:BFRI) and Dogwood Therapeutics (NASDAQ:DWTX) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, risk, analyst recommendations, profitability, earnings, media sentiment, institutional ownership and valuation.

In the previous week, Dogwood Therapeutics had 1 more articles in the media than Biofrontera. MarketBeat recorded 3 mentions for Dogwood Therapeutics and 2 mentions for Biofrontera. Biofrontera's average media sentiment score of 1.00 beat Dogwood Therapeutics' score of 0.37 indicating that Biofrontera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biofrontera
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Dogwood Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

10.1% of Biofrontera shares are owned by institutional investors. Comparatively, 9.1% of Dogwood Therapeutics shares are owned by institutional investors. 8.1% of Biofrontera shares are owned by company insiders. Comparatively, 0.3% of Dogwood Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Dogwood Therapeutics has a net margin of 0.00% compared to Biofrontera's net margin of -25.66%. Dogwood Therapeutics' return on equity of -108.57% beat Biofrontera's return on equity.

Company Net Margins Return on Equity Return on Assets
Biofrontera-25.66% -515.34% -53.91%
Dogwood Therapeutics N/A -108.57%-30.28%

Biofrontera has higher revenue and earnings than Dogwood Therapeutics. Biofrontera is trading at a lower price-to-earnings ratio than Dogwood Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biofrontera$41.71M0.37-$10.54M-$0.97N/A
Dogwood TherapeuticsN/AN/A-$34.26M-$10.60N/A

Dogwood Therapeutics has a consensus price target of $12.00, indicating a potential upside of 555.74%. Given Dogwood Therapeutics' higher possible upside, analysts clearly believe Dogwood Therapeutics is more favorable than Biofrontera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biofrontera
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Dogwood Therapeutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Biofrontera has a beta of 0.78, indicating that its share price is 22% less volatile than the broader market. Comparatively, Dogwood Therapeutics has a beta of 1.71, indicating that its share price is 71% more volatile than the broader market.

Summary

Dogwood Therapeutics beats Biofrontera on 7 of the 13 factors compared between the two stocks.

How does Biofrontera compare to RYTHM?

Biofrontera (NASDAQ:BFRI) and RYTHM (NASDAQ:RYM) are both small-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their dividends, institutional ownership, risk, profitability, media sentiment, valuation, analyst recommendations and earnings.

10.1% of Biofrontera shares are owned by institutional investors. Comparatively, 6.0% of RYTHM shares are owned by institutional investors. 8.1% of Biofrontera shares are owned by company insiders. Comparatively, 3.5% of RYTHM shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Biofrontera has a beta of 0.78, meaning that its share price is 22% less volatile than the broader market. Comparatively, RYTHM has a beta of 9.47, meaning that its share price is 847% more volatile than the broader market.

In the previous week, RYTHM had 2 more articles in the media than Biofrontera. MarketBeat recorded 4 mentions for RYTHM and 2 mentions for Biofrontera. Biofrontera's average media sentiment score of 1.00 beat RYTHM's score of 0.75 indicating that Biofrontera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Biofrontera
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
RYTHM
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biofrontera
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
RYTHM
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Biofrontera has higher revenue and earnings than RYTHM. RYTHM is trading at a lower price-to-earnings ratio than Biofrontera, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biofrontera$41.71M0.37-$10.54M-$0.97N/A
RYTHM$17.28M2.82-$33.26M-$10.53N/A

RYTHM has a net margin of -6.20% compared to Biofrontera's net margin of -25.66%. RYTHM's return on equity of -12.57% beat Biofrontera's return on equity.

Company Net Margins Return on Equity Return on Assets
Biofrontera-25.66% -515.34% -53.91%
RYTHM -6.20%-12.57%-2.60%

Summary

Biofrontera beats RYTHM on 9 of the 15 factors compared between the two stocks.

How does Biofrontera compare to Scilex?

Biofrontera (NASDAQ:BFRI) and Scilex (NASDAQ:SCLX) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their dividends, institutional ownership, earnings, valuation, media sentiment, profitability, analyst recommendations and risk.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Biofrontera
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Scilex
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

In the previous week, Biofrontera had 2 more articles in the media than Scilex. MarketBeat recorded 2 mentions for Biofrontera and 0 mentions for Scilex. Biofrontera's average media sentiment score of 1.00 beat Scilex's score of 0.00 indicating that Biofrontera is being referred to more favorably in the media.

Company Overall Sentiment
Biofrontera Positive
Scilex Neutral

Biofrontera has higher revenue and earnings than Scilex. Biofrontera is trading at a lower price-to-earnings ratio than Scilex, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Biofrontera$41.71M0.37-$10.54M-$0.97N/A
Scilex$30.25M1.88-$358.73M-$40.47N/A

Biofrontera has a net margin of -25.66% compared to Scilex's net margin of -1,110.17%. Scilex's return on equity of 0.00% beat Biofrontera's return on equity.

Company Net Margins Return on Equity Return on Assets
Biofrontera-25.66% -515.34% -53.91%
Scilex -1,110.17%N/A -143.55%

10.1% of Biofrontera shares are held by institutional investors. Comparatively, 69.7% of Scilex shares are held by institutional investors. 8.1% of Biofrontera shares are held by insiders. Comparatively, 4.5% of Scilex shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Biofrontera has a beta of 0.78, indicating that its stock price is 22% less volatile than the broader market. Comparatively, Scilex has a beta of 1.67, indicating that its stock price is 67% more volatile than the broader market.

Summary

Biofrontera beats Scilex on 10 of the 15 factors compared between the two stocks.

How does Biofrontera compare to SCYNEXIS?

SCYNEXIS (NASDAQ:SCYX) and Biofrontera (NASDAQ:BFRI) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, dividends, valuation, media sentiment, analyst recommendations, institutional ownership, profitability and earnings.

In the previous week, SCYNEXIS had 5 more articles in the media than Biofrontera. MarketBeat recorded 7 mentions for SCYNEXIS and 2 mentions for Biofrontera. Biofrontera's average media sentiment score of 1.00 beat SCYNEXIS's score of 0.72 indicating that Biofrontera is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
SCYNEXIS
1 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Biofrontera
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Biofrontera has a net margin of -25.66% compared to SCYNEXIS's net margin of -41.79%. SCYNEXIS's return on equity of -57.16% beat Biofrontera's return on equity.

Company Net Margins Return on Equity Return on Assets
SCYNEXIS-41.79% -57.16% -39.48%
Biofrontera -25.66%-515.34%-53.91%

54.4% of SCYNEXIS shares are held by institutional investors. Comparatively, 10.1% of Biofrontera shares are held by institutional investors. 4.1% of SCYNEXIS shares are held by insiders. Comparatively, 8.1% of Biofrontera shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

SCYNEXIS has higher earnings, but lower revenue than Biofrontera. SCYNEXIS is trading at a lower price-to-earnings ratio than Biofrontera, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SCYNEXIS$20.60M2.49-$8.61M-$3.84N/A
Biofrontera$41.71M0.37-$10.54M-$0.97N/A

SCYNEXIS has a beta of 1.09, meaning that its stock price is 9% more volatile than the broader market. Comparatively, Biofrontera has a beta of 0.78, meaning that its stock price is 22% less volatile than the broader market.

SCYNEXIS presently has a consensus price target of $24.00, suggesting a potential upside of 365.12%. Given SCYNEXIS's stronger consensus rating and higher probable upside, equities research analysts clearly believe SCYNEXIS is more favorable than Biofrontera.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SCYNEXIS
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Biofrontera
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

SCYNEXIS beats Biofrontera on 10 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding BFRI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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BFRI vs. The Competition

MetricBiofronteraPharmaceuticals IndustryHealthcare SectorNASDAQ Exchange
Market Cap$16.26M$11.84B$7.02B$12.98B
Dividend YieldN/A2.69%2.58%10.20%
P/E Ratio-1.25788.51269.1924.72
Price / Sales0.37740.84588.7697.77
Price / CashN/A15.1228.8937.42
Price / Book1.3410.3311.276.42
Net Income-$10.54M$2.77B$3.45B$347.03M
7 Day Performance1.68%2.04%3.56%2.49%
1 Month Performance10.00%-1.57%-0.58%-1.04%
1 Year Performance27.84%191.33%77.52%23.22%

Biofrontera Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
BFRI
Biofrontera
1.4322 of 5 stars
$1.21
-4.7%
N/A+34.2%$16.26M$41.71MN/A70
ZYBT
Zhengye Biotechnology
0.5945 of 5 stars
$2.36
+84.4%
N/A-63.7%$60.66M$16.64MN/A278
DWTX
Dogwood Therapeutics
2.9594 of 5 stars
$1.83
+2.2%
$12.00
+555.7%
-62.6%$60.20MN/AN/A5
RYM
RYTHM
1.1133 of 5 stars
$24.99
-1.8%
N/AN/A$55.44M$17.28MN/A140
SCLX
Scilex
0.2662 of 5 stars
$6.52
+0.8%
N/A-55.8%$54.94M$30.25MN/A80

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This page (NASDAQ:BFRI) was last updated on 8/10/2026 by MarketBeat.com Staff.
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