Free Trial

Hyperion DeFi (HYPD) Competitors

Hyperion DeFi logo
$2.72 0.00 (0.00%)
Closing price 06/12/2026 04:00 PM Eastern
Extended Trading
$2.77 +0.05 (+1.76%)
As of 06/12/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

HYPD vs. VYGR, WHWK, FHTX, CGEN, and NKTX

Should you buy Hyperion DeFi stock or one of its competitors? MarketBeat compares Hyperion DeFi with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Hyperion DeFi include Voyager Therapeutics (VYGR), Whitehawk Therapeutics (WHWK), Foghorn Therapeutics (FHTX), Compugen (CGEN), and Nkarta (NKTX). These companies are all part of the "pharmaceutical products" industry.

How does Hyperion DeFi compare to Voyager Therapeutics?

Hyperion DeFi (NASDAQ:HYPD) and Voyager Therapeutics (NASDAQ:VYGR) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, valuation, media sentiment, risk, earnings, analyst recommendations, dividends and institutional ownership.

Hyperion DeFi presently has a consensus price target of $5.65, indicating a potential upside of 107.72%. Voyager Therapeutics has a consensus price target of $16.50, indicating a potential upside of 371.43%. Given Voyager Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Voyager Therapeutics is more favorable than Hyperion DeFi.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Hyperion DeFi
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25
Voyager Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

In the previous week, Hyperion DeFi had 1 more articles in the media than Voyager Therapeutics. MarketBeat recorded 6 mentions for Hyperion DeFi and 5 mentions for Voyager Therapeutics. Voyager Therapeutics' average media sentiment score of 0.43 beat Hyperion DeFi's score of 0.41 indicating that Voyager Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Hyperion DeFi
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Voyager Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Hyperion DeFi has a net margin of 0.00% compared to Voyager Therapeutics' net margin of -319.61%. Voyager Therapeutics' return on equity of -55.97% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
Hyperion DeFiN/A -91.59% -73.08%
Voyager Therapeutics -319.61%-55.97%-43.12%

Hyperion DeFi has a beta of 2.48, meaning that its stock price is 148% more volatile than the broader market. Comparatively, Voyager Therapeutics has a beta of 1.25, meaning that its stock price is 25% more volatile than the broader market.

Hyperion DeFi has higher earnings, but lower revenue than Voyager Therapeutics. Voyager Therapeutics is trading at a lower price-to-earnings ratio than Hyperion DeFi, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Hyperion DeFi$810K50.91-$45.31M-$9.95N/A
Voyager Therapeutics$40.37M5.24-$119.72M-$1.97N/A

25.8% of Hyperion DeFi shares are held by institutional investors. Comparatively, 48.0% of Voyager Therapeutics shares are held by institutional investors. 7.5% of Hyperion DeFi shares are held by company insiders. Comparatively, 12.7% of Voyager Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Summary

Voyager Therapeutics beats Hyperion DeFi on 10 of the 16 factors compared between the two stocks.

How does Hyperion DeFi compare to Whitehawk Therapeutics?

Whitehawk Therapeutics (NASDAQ:WHWK) and Hyperion DeFi (NASDAQ:HYPD) are both small-cap pharmaceutical products companies, but which is the superior investment? We will contrast the two businesses based on the strength of their dividends, risk, earnings, institutional ownership, media sentiment, profitability, valuation and analyst recommendations.

52.1% of Whitehawk Therapeutics shares are owned by institutional investors. Comparatively, 25.8% of Hyperion DeFi shares are owned by institutional investors. 49.9% of Whitehawk Therapeutics shares are owned by company insiders. Comparatively, 7.5% of Hyperion DeFi shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Whitehawk Therapeutics' return on equity of -79.63% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
Whitehawk TherapeuticsN/A -79.63% -74.01%
Hyperion DeFi N/A -91.59%-73.08%

Whitehawk Therapeutics currently has a consensus price target of $7.33, suggesting a potential upside of 76.28%. Hyperion DeFi has a consensus price target of $5.65, suggesting a potential upside of 107.72%. Given Hyperion DeFi's higher possible upside, analysts clearly believe Hyperion DeFi is more favorable than Whitehawk Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Whitehawk Therapeutics
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.50
Hyperion DeFi
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25

Whitehawk Therapeutics has a beta of 0.77, indicating that its share price is 23% less volatile than the broader market. Comparatively, Hyperion DeFi has a beta of 2.48, indicating that its share price is 148% more volatile than the broader market.

Whitehawk Therapeutics has higher revenue and earnings than Hyperion DeFi. Whitehawk Therapeutics is trading at a lower price-to-earnings ratio than Hyperion DeFi, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Whitehawk Therapeutics$7.14M28.81-$20.60M-$1.68N/A
Hyperion DeFi$810K50.91-$45.31M-$9.95N/A

In the previous week, Hyperion DeFi had 3 more articles in the media than Whitehawk Therapeutics. MarketBeat recorded 6 mentions for Hyperion DeFi and 3 mentions for Whitehawk Therapeutics. Whitehawk Therapeutics' average media sentiment score of 1.16 beat Hyperion DeFi's score of 0.41 indicating that Whitehawk Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Whitehawk Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Hyperion DeFi
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Whitehawk Therapeutics beats Hyperion DeFi on 9 of the 16 factors compared between the two stocks.

How does Hyperion DeFi compare to Foghorn Therapeutics?

Hyperion DeFi (NASDAQ:HYPD) and Foghorn Therapeutics (NASDAQ:FHTX) are both small-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, media sentiment, valuation, earnings, dividends, risk, analyst recommendations and institutional ownership.

Hyperion DeFi has a net margin of 0.00% compared to Foghorn Therapeutics' net margin of -266.88%. Foghorn Therapeutics' return on equity of 0.00% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
Hyperion DeFiN/A -91.59% -73.08%
Foghorn Therapeutics -266.88%N/A -35.38%

Hyperion DeFi has higher earnings, but lower revenue than Foghorn Therapeutics. Foghorn Therapeutics is trading at a lower price-to-earnings ratio than Hyperion DeFi, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Hyperion DeFi$810K50.91-$45.31M-$9.95N/A
Foghorn Therapeutics$30.91M7.94-$74.28M-$1.16N/A

In the previous week, Hyperion DeFi had 3 more articles in the media than Foghorn Therapeutics. MarketBeat recorded 6 mentions for Hyperion DeFi and 3 mentions for Foghorn Therapeutics. Foghorn Therapeutics' average media sentiment score of 0.62 beat Hyperion DeFi's score of 0.41 indicating that Foghorn Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Hyperion DeFi
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Foghorn Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Hyperion DeFi has a beta of 2.48, suggesting that its stock price is 148% more volatile than the broader market. Comparatively, Foghorn Therapeutics has a beta of 2.89, suggesting that its stock price is 189% more volatile than the broader market.

25.8% of Hyperion DeFi shares are held by institutional investors. Comparatively, 61.6% of Foghorn Therapeutics shares are held by institutional investors. 7.5% of Hyperion DeFi shares are held by insiders. Comparatively, 9.0% of Foghorn Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Hyperion DeFi presently has a consensus target price of $5.65, indicating a potential upside of 107.72%. Foghorn Therapeutics has a consensus target price of $11.43, indicating a potential upside of 173.41%. Given Foghorn Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Foghorn Therapeutics is more favorable than Hyperion DeFi.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Hyperion DeFi
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25
Foghorn Therapeutics
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Summary

Foghorn Therapeutics beats Hyperion DeFi on 11 of the 16 factors compared between the two stocks.

How does Hyperion DeFi compare to Compugen?

Compugen (NASDAQ:CGEN) and Hyperion DeFi (NASDAQ:HYPD) are both small-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, media sentiment, valuation, risk, institutional ownership, profitability, analyst recommendations and dividends.

12.2% of Compugen shares are owned by institutional investors. Comparatively, 25.8% of Hyperion DeFi shares are owned by institutional investors. 9.5% of Compugen shares are owned by insiders. Comparatively, 7.5% of Hyperion DeFi shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Compugen presently has a consensus price target of $5.00, indicating a potential upside of 145.10%. Hyperion DeFi has a consensus price target of $5.65, indicating a potential upside of 107.72%. Given Compugen's stronger consensus rating and higher possible upside, equities research analysts plainly believe Compugen is more favorable than Hyperion DeFi.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Compugen
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.80
Hyperion DeFi
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25

Compugen has higher revenue and earnings than Hyperion DeFi. Hyperion DeFi is trading at a lower price-to-earnings ratio than Compugen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Compugen$72.76M2.65$35.34M$0.375.51
Hyperion DeFi$810K50.91-$45.31M-$9.95N/A

Compugen has a net margin of 47.97% compared to Hyperion DeFi's net margin of 0.00%. Compugen's return on equity of 47.72% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
Compugen47.97% 47.72% 27.51%
Hyperion DeFi N/A -91.59%-73.08%

Compugen has a beta of 2.74, suggesting that its share price is 174% more volatile than the broader market. Comparatively, Hyperion DeFi has a beta of 2.48, suggesting that its share price is 148% more volatile than the broader market.

In the previous week, Hyperion DeFi had 3 more articles in the media than Compugen. MarketBeat recorded 6 mentions for Hyperion DeFi and 3 mentions for Compugen. Compugen's average media sentiment score of 0.62 beat Hyperion DeFi's score of 0.41 indicating that Compugen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Compugen
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Hyperion DeFi
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Compugen beats Hyperion DeFi on 13 of the 16 factors compared between the two stocks.

How does Hyperion DeFi compare to Nkarta?

Hyperion DeFi (NASDAQ:HYPD) and Nkarta (NASDAQ:NKTX) are both small-cap medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, earnings, dividends, institutional ownership, valuation, risk, media sentiment and profitability.

25.8% of Hyperion DeFi shares are owned by institutional investors. Comparatively, 80.5% of Nkarta shares are owned by institutional investors. 7.5% of Hyperion DeFi shares are owned by company insiders. Comparatively, 9.8% of Nkarta shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Hyperion DeFi has higher revenue and earnings than Nkarta. Nkarta is trading at a lower price-to-earnings ratio than Hyperion DeFi, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Hyperion DeFi$810K50.91-$45.31M-$9.95N/A
NkartaN/AN/A-$104.08M-$1.34N/A

In the previous week, Hyperion DeFi had 4 more articles in the media than Nkarta. MarketBeat recorded 6 mentions for Hyperion DeFi and 2 mentions for Nkarta. Nkarta's average media sentiment score of 0.93 beat Hyperion DeFi's score of 0.41 indicating that Nkarta is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Hyperion DeFi
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Nkarta
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Hyperion DeFi has a beta of 2.48, indicating that its share price is 148% more volatile than the broader market. Comparatively, Nkarta has a beta of 0.91, indicating that its share price is 9% less volatile than the broader market.

Hyperion DeFi presently has a consensus price target of $5.65, suggesting a potential upside of 107.72%. Nkarta has a consensus price target of $10.75, suggesting a potential upside of 275.87%. Given Nkarta's stronger consensus rating and higher possible upside, analysts clearly believe Nkarta is more favorable than Hyperion DeFi.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Hyperion DeFi
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25
Nkarta
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.80

Nkarta's return on equity of -30.90% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
Hyperion DeFiN/A -91.59% -73.08%
Nkarta N/A -30.90%-24.20%

Summary

Nkarta beats Hyperion DeFi on 9 of the 14 factors compared between the two stocks.

Get Hyperion DeFi News Delivered to You Automatically

Sign up to receive the latest news and ratings for HYPD and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding HYPD and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

HYPD vs. The Competition

MetricHyperion DeFiBiotechnology IndustryMedical SectorNASDAQ Exchange
Market Cap$41.24M$445.77M$6.52B$12.05B
Dividend YieldN/A3.88%2.67%5.66%
P/E Ratio-0.273.1824.0024.42
Price / Sales50.916,466.56514.65112.54
Price / CashN/A13.1327.4837.92
Price / Book0.5889.4610.696.82
Net Income-$45.31M-$96.07M$3.57B$337.56M
7 Day Performance-7.17%0.12%0.61%1.16%
1 Month Performance-19.05%-0.24%1.56%3.16%
1 Year Performance11.48%56.29%25.44%30.60%

Hyperion DeFi Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
HYPD
Hyperion DeFi
4.1505 of 5 stars
$2.72
flat
$5.65
+107.7%
+11.5%$41.24M$810KN/A40
VYGR
Voyager Therapeutics
3.4827 of 5 stars
$3.75
-3.2%
$16.50
+340.6%
+6.1%$233.83M$36.49MN/A100
WHWK
Whitehawk Therapeutics
3.8893 of 5 stars
$4.21
-10.9%
$7.33
+74.4%
N/A$233.42M$7.14MN/A21
FHTX
Foghorn Therapeutics
2.4749 of 5 stars
$3.77
-12.0%
$11.43
+203.5%
-3.2%$233.39M$28.22MN/A120
CGEN
Compugen
3.9237 of 5 stars
$2.33
-11.6%
$5.00
+115.1%
+24.4%$232.60M$72.66M6.4270

Related Companies and Tools


This page (NASDAQ:HYPD) was last updated on 6/15/2026 by MarketBeat.com Staff.
From Our Partners