Prothena (PRTA) Competitors $8.21 -0.22 (-2.61%) Closing price 04:00 PM EasternExtended Trading$8.22 +0.01 (+0.12%) As of 04:46 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock PRTA vs. APGE, CDTX, BEAM, BHVN, TWST, IMCR, AUPH, TVTX, ARDX, and WVEShould you be buying Prothena stock or one of its competitors? The main competitors of Prothena include Apogee Therapeutics (APGE), Cidara Therapeutics (CDTX), Beam Therapeutics (BEAM), Biohaven (BHVN), Twist Bioscience (TWST), Immunocore (IMCR), Aurinia Pharmaceuticals (AUPH), Travere Therapeutics (TVTX), Ardelyx (ARDX), and WAVE Life Sciences (WVE). These companies are all part of the "pharmaceutical products" industry. Prothena vs. Its Competitors Apogee Therapeutics Cidara Therapeutics Beam Therapeutics Biohaven Twist Bioscience Immunocore Aurinia Pharmaceuticals Travere Therapeutics Ardelyx WAVE Life Sciences Prothena (NASDAQ:PRTA) and Apogee Therapeutics (NASDAQ:APGE) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, media sentiment, risk, valuation, institutional ownership, profitability, dividends and analyst recommendations. Which has higher valuation & earnings, PRTA or APGE? Prothena has higher revenue and earnings than Apogee Therapeutics. Apogee Therapeutics is trading at a lower price-to-earnings ratio than Prothena, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioProthena$10.34M42.74-$122.31M-$5.64-1.46Apogee TherapeuticsN/AN/A-$182.15M-$4.13-8.93 Which has more risk & volatility, PRTA or APGE? Prothena has a beta of -0.04, indicating that its share price is 104% less volatile than the S&P 500. Comparatively, Apogee Therapeutics has a beta of 1.42, indicating that its share price is 42% more volatile than the S&P 500. Do analysts rate PRTA or APGE? Prothena presently has a consensus price target of $19.75, suggesting a potential upside of 140.56%. Apogee Therapeutics has a consensus price target of $97.29, suggesting a potential upside of 163.79%. Given Apogee Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Apogee Therapeutics is more favorable than Prothena.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Prothena 1 Sell rating(s) 4 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 2.33Apogee Therapeutics 0 Sell rating(s) 1 Hold rating(s) 7 Buy rating(s) 0 Strong Buy rating(s) 2.88 Is PRTA or APGE more profitable? Apogee Therapeutics has a net margin of 0.00% compared to Prothena's net margin of -2,929.30%. Apogee Therapeutics' return on equity of -34.65% beat Prothena's return on equity.Company Net Margins Return on Equity Return on Assets Prothena-2,929.30% -62.17% -54.43% Apogee Therapeutics N/A -34.65%-32.76% Does the media prefer PRTA or APGE? In the previous week, Apogee Therapeutics had 10 more articles in the media than Prothena. MarketBeat recorded 13 mentions for Apogee Therapeutics and 3 mentions for Prothena. Apogee Therapeutics' average media sentiment score of 1.21 beat Prothena's score of 0.90 indicating that Apogee Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Prothena 1 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Apogee Therapeutics 8 Very Positive mention(s) 0 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do institutionals and insiders hold more shares of PRTA or APGE? 97.1% of Prothena shares are held by institutional investors. Comparatively, 79.0% of Apogee Therapeutics shares are held by institutional investors. 9.2% of Prothena shares are held by company insiders. Comparatively, 42.8% of Apogee Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth. SummaryApogee Therapeutics beats Prothena on 11 of the 15 factors compared between the two stocks. Get Prothena News Delivered to You Automatically Sign up to receive the latest news and ratings for PRTA and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding PRTA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PRTA vs. The Competition Export to ExcelMetricProthenaMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$441.94M$3.14B$5.81B$10.16BDividend YieldN/A2.32%5.69%4.60%P/E Ratio-1.4621.3674.6225.97Price / Sales42.74257.18454.4485.61Price / CashN/A45.3337.0859.91Price / Book0.919.6112.156.29Net Income-$122.31M-$53.29M$3.28B$270.77M7 Day Performance-3.98%0.36%0.98%3.32%1 Month Performance8.89%8.98%7.19%6.40%1 Year Performance-60.38%13.18%63.14%28.24% Prothena Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PRTAProthena3.3013 of 5 stars$8.21-2.6%$19.75+140.6%-59.7%$441.94M$10.34M-1.46130News CoverageAPGEApogee Therapeutics2.9176 of 5 stars$36.37-0.7%$97.29+167.5%-26.4%$1.68BN/A-8.8191News CoveragePositive NewsCDTXCidara Therapeutics3.2774 of 5 stars$65.39+0.2%$64.14-1.9%+458.3%$1.66B$1.27M-5.8890Positive NewsBEAMBeam Therapeutics2.861 of 5 stars$16.36-2.9%$48.45+196.2%-10.7%$1.66B$63.52M-3.64510BHVNBiohaven3.2692 of 5 stars$15.35-1.1%$54.23+253.2%-60.4%$1.63BN/A-2.00239Trending NewsGap DownTWSTTwist Bioscience3.987 of 5 stars$26.97+1.4%$49.40+83.2%-42.3%$1.63B$312.97M-18.60990News CoverageIMCRImmunocore1.859 of 5 stars$32.22-0.1%$56.89+76.6%+10.9%$1.62B$310.20M-80.55320AUPHAurinia Pharmaceuticals2.9714 of 5 stars$11.99-0.7%$12.00+0.1%+95.7%$1.58B$235.13M27.88300News CoveragePositive NewsTVTXTravere Therapeutics2.983 of 5 stars$17.50-1.1%$33.43+91.0%+104.2%$1.56B$233.18M-8.58460News CoverageAnalyst ForecastARDXArdelyx4.6258 of 5 stars$6.36-0.3%$11.50+80.8%+12.1%$1.53B$333.61M-27.6590Positive NewsWVEWAVE Life Sciences4.5513 of 5 stars$9.60-3.3%$20.27+111.1%+21.4%$1.53B$108.30M-10.67240Positive News Related Companies and Tools Related Companies Apogee Therapeutics Competitors Cidara Therapeutics Competitors Beam Therapeutics Competitors Biohaven Competitors Twist Bioscience Competitors Immunocore Competitors Aurinia Pharmaceuticals Competitors Travere Therapeutics Competitors Ardelyx Competitors WAVE Life Sciences Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PRTA) was last updated on 9/12/2025 by MarketBeat.com Staff From Our PartnersForget NVDA. 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