Scilex (SCLX) Competitors $6.00 -0.24 (-3.85%) Closing price 03:44 PM EasternExtended Trading$6.23 +0.23 (+3.83%) As of 04:26 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock SCLX vs. ACTU, ALEC, LYEL, LXEO, FATE, BDTX, VXRT, NKTX, IKT, and RAPTShould you be buying Scilex stock or one of its competitors? The main competitors of Scilex include Actuate Therapeutics (ACTU), Alector (ALEC), Lyell Immunopharma (LYEL), Lexeo Therapeutics (LXEO), Fate Therapeutics (FATE), Black Diamond Therapeutics (BDTX), Vaxart (VXRT), Nkarta (NKTX), Inhibikase Therapeutics (IKT), and Rapt Therapeutics (RAPT). These companies are all part of the "pharmaceutical products" industry. Scilex vs. Its Competitors Actuate Therapeutics Alector Lyell Immunopharma Lexeo Therapeutics Fate Therapeutics Black Diamond Therapeutics Vaxart Nkarta Inhibikase Therapeutics Rapt Therapeutics Scilex (NASDAQ:SCLX) and Actuate Therapeutics (NASDAQ:ACTU) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their dividends, valuation, risk, institutional ownership, analyst recommendations, media sentiment, earnings and profitability. Does the media favor SCLX or ACTU? In the previous week, Actuate Therapeutics had 7 more articles in the media than Scilex. MarketBeat recorded 8 mentions for Actuate Therapeutics and 1 mentions for Scilex. Actuate Therapeutics' average media sentiment score of 1.34 beat Scilex's score of 0.00 indicating that Actuate Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Scilex 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Actuate Therapeutics 4 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is SCLX or ACTU more profitable? Actuate Therapeutics has a net margin of 0.00% compared to Scilex's net margin of -146.93%. Company Net Margins Return on Equity Return on Assets Scilex-146.93% N/A -82.65% Actuate Therapeutics N/A N/A -339.73% Do analysts recommend SCLX or ACTU? Scilex currently has a consensus target price of $455.00, indicating a potential upside of 7,483.33%. Actuate Therapeutics has a consensus target price of $20.50, indicating a potential upside of 214.18%. Given Scilex's higher possible upside, equities research analysts plainly believe Scilex is more favorable than Actuate Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Scilex 0 Sell rating(s) 2 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 2.50Actuate Therapeutics 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 3.00 Do institutionals and insiders believe in SCLX or ACTU? 69.7% of Scilex shares are held by institutional investors. 7.9% of Scilex shares are held by company insiders. Comparatively, 69.3% of Actuate Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term. Which has preferable valuation & earnings, SCLX or ACTU? Actuate Therapeutics has lower revenue, but higher earnings than Scilex. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioScilex$56.59M0.74-$72.81M-$29.02-0.21Actuate TherapeuticsN/AN/A-$27.28MN/AN/A SummaryActuate Therapeutics beats Scilex on 6 of the 10 factors compared between the two stocks. Get Scilex News Delivered to You Automatically Sign up to receive the latest news and ratings for SCLX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SCLX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SCLX vs. The Competition Export to ExcelMetricScilexMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$43.38M$2.91B$5.54B$8.95BDividend YieldN/A2.42%5.38%4.08%P/E Ratio-0.2121.5627.4020.04Price / Sales0.74281.10419.46118.60Price / CashN/A41.9536.6357.47Price / Book-0.227.518.085.67Net Income-$72.81M-$55.05M$3.16B$248.47M7 Day Performance13.21%3.16%2.12%2.90%1 Month Performance9.69%5.92%4.43%5.75%1 Year Performance-90.48%5.82%35.62%21.36% Scilex Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SCLXScilex1.7509 of 5 stars$6.00-3.8%$455.00+7,483.3%-90.8%$43.38M$56.59M-0.2180ACTUActuate Therapeutics2.9689 of 5 stars$7.05-5.6%$20.50+190.8%N/A$138.32MN/A0.0010Insider TradeALECAlector3.6477 of 5 stars$1.38-6.5%$4.00+190.9%-65.4%$137.49M$100.56M-1.09270LYELLyell Immunopharma2.7754 of 5 stars$8.99+3.5%$20.00+122.5%-68.8%$133.14M$60K-0.36270LXEOLexeo Therapeutics1.752 of 5 stars$3.96+1.3%$16.60+319.2%-68.8%$131.46M$650K-1.2058News CoverageFATEFate Therapeutics4.0575 of 5 stars$1.14-4.2%$3.83+236.3%-65.2%$130.64M$13.63M-0.77550News CoverageGap UpBDTXBlack Diamond Therapeutics3.2879 of 5 stars$2.27-2.6%$14.60+543.2%-38.2%$129.08M$70M37.8390Positive NewsAnalyst UpgradeVXRTVaxart2.2846 of 5 stars$0.56-3.4%$3.00+435.3%-35.4%$127.95M$47.40M-2.08120NKTXNkarta2.2595 of 5 stars$1.75-1.4%$14.33+721.4%-66.9%$123.82MN/A-1.16140News CoverageIKTInhibikase Therapeutics1.4003 of 5 stars$1.66flat$6.50+291.6%+52.9%$123.41M$260K-0.626News CoverageRAPTRapt Therapeutics4.3505 of 5 stars$7.44+0.1%$24.00+222.6%-64.1%$123.03M$1.53M-0.3980 Related Companies and Tools Related Companies ACTU Alternatives ALEC Alternatives LYEL Alternatives LXEO Alternatives FATE Alternatives BDTX Alternatives VXRT Alternatives NKTX Alternatives IKT Alternatives RAPT Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SCLX) was last updated on 7/3/2025 by MarketBeat.com Staff From Our PartnersTrump’s New Order Could Boost Social Security Benefits by 400%If you collect—or plan to collect—Social Security, you need to see this. 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